AR059054A1 - Variante d3n de glicosilacion fsh novedosa - Google Patents
Variante d3n de glicosilacion fsh novedosaInfo
- Publication number
- AR059054A1 AR059054A1 ARP070100200A ARP070100200A AR059054A1 AR 059054 A1 AR059054 A1 AR 059054A1 AR P070100200 A ARP070100200 A AR P070100200A AR P070100200 A ARP070100200 A AR P070100200A AR 059054 A1 AR059054 A1 AR 059054A1
- Authority
- AR
- Argentina
- Prior art keywords
- novedosa
- glycosilation
- variante
- fsh mutant
- folliclegenesis
- Prior art date
Links
- 230000013595 glycosylation Effects 0.000 abstract 1
- 238000006206 glycosylation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/24—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
- Pregnancy & Childbirth (AREA)
- Physics & Mathematics (AREA)
- Gynecology & Obstetrics (AREA)
- Microbiology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Se describe el mutante de la FSH con glicosilacion aumentada y vida media más larga. También se describe el uso de este mutante de la FSH para inducir la folículo-génesis en pacientes humanos.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75948606P | 2006-01-17 | 2006-01-17 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR059054A1 true AR059054A1 (es) | 2008-03-12 |
Family
ID=38163618
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP070100200A AR059054A1 (es) | 2006-01-17 | 2007-01-17 | Variante d3n de glicosilacion fsh novedosa |
Country Status (22)
Country | Link |
---|---|
US (1) | US7956034B2 (es) |
EP (1) | EP1981908B1 (es) |
JP (1) | JP2009523445A (es) |
KR (1) | KR20080094697A (es) |
CN (1) | CN101370825B (es) |
AR (1) | AR059054A1 (es) |
AT (1) | ATE487738T1 (es) |
AU (1) | AU2007207697B2 (es) |
BR (1) | BRPI0706628A2 (es) |
CA (1) | CA2633844A1 (es) |
CY (1) | CY1110953T1 (es) |
DE (1) | DE602007010425D1 (es) |
DK (1) | DK1981908T3 (es) |
EA (1) | EA013974B1 (es) |
HR (1) | HRP20100610T1 (es) |
IL (1) | IL192547A (es) |
PL (1) | PL1981908T3 (es) |
PT (1) | PT1981908E (es) |
RS (1) | RS51792B (es) |
SI (1) | SI1981908T1 (es) |
WO (1) | WO2007084441A2 (es) |
ZA (1) | ZA200805194B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA015901B1 (ru) | 2005-08-26 | 2011-12-30 | Арес Трейдинг С.А. | Способ получения гликозилированного интерферона бета |
US8604175B2 (en) * | 2005-12-09 | 2013-12-10 | Ares Trading S.A. | Method for purifying FSH or a FSH mutant |
JP5249044B2 (ja) | 2005-12-22 | 2013-07-31 | メルク セローノ ソシエテ アノニム | Fsh突然変異体 |
JP2011500757A (ja) * | 2007-10-22 | 2011-01-06 | メルク セローノ ソシエテ アノニム | Fc含有タンパク質の精製方法 |
EP2203474A1 (en) * | 2007-10-22 | 2010-07-07 | Merck Serono S.A. | Method for purifying fc-fusion proteins |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3950484B2 (ja) * | 1997-06-25 | 2007-08-01 | アプライド・リサーチ・システムズ・エイアールエス・ホールディング・ナムローゼ・フェンノートシャップ | ジスルフィド架橋結合した糖タンパク質ホルモン類似体類およびそれらの調製および使用 |
WO2001058493A1 (en) * | 2000-02-11 | 2001-08-16 | Maxygen Aps | Conjugates of follicle stimulating hormones |
IL161541A0 (en) * | 2001-10-22 | 2004-09-27 | Applied Research Systems | Mutant glycoproteins |
UA88879C2 (en) * | 2003-09-02 | 2009-12-10 | Эплайд Рисерч Системз Эрс Холдинг Н.В. | Fsh glycosylation mutant |
US8604175B2 (en) * | 2005-12-09 | 2013-12-10 | Ares Trading S.A. | Method for purifying FSH or a FSH mutant |
-
2007
- 2007-01-16 AT AT07716617T patent/ATE487738T1/de active
- 2007-01-16 CN CN2007800030734A patent/CN101370825B/zh not_active Expired - Fee Related
- 2007-01-16 AU AU2007207697A patent/AU2007207697B2/en not_active Ceased
- 2007-01-16 JP JP2008551305A patent/JP2009523445A/ja active Pending
- 2007-01-16 EA EA200870177A patent/EA013974B1/ru not_active IP Right Cessation
- 2007-01-16 DK DK07716617.1T patent/DK1981908T3/da active
- 2007-01-16 DE DE602007010425T patent/DE602007010425D1/de active Active
- 2007-01-16 US US12/158,539 patent/US7956034B2/en not_active Expired - Fee Related
- 2007-01-16 PT PT07716617T patent/PT1981908E/pt unknown
- 2007-01-16 BR BRPI0706628-7A patent/BRPI0706628A2/pt not_active IP Right Cessation
- 2007-01-16 EP EP07716617A patent/EP1981908B1/en active Active
- 2007-01-16 RS RS20100568A patent/RS51792B/en unknown
- 2007-01-16 KR KR1020087020053A patent/KR20080094697A/ko not_active Application Discontinuation
- 2007-01-16 SI SI200730438T patent/SI1981908T1/sl unknown
- 2007-01-16 CA CA002633844A patent/CA2633844A1/en not_active Abandoned
- 2007-01-16 ZA ZA200805194A patent/ZA200805194B/xx unknown
- 2007-01-16 WO PCT/US2007/001004 patent/WO2007084441A2/en active Application Filing
- 2007-01-16 PL PL07716617T patent/PL1981908T3/pl unknown
- 2007-01-17 AR ARP070100200A patent/AR059054A1/es not_active Application Discontinuation
-
2008
- 2008-06-30 IL IL192547A patent/IL192547A/en not_active IP Right Cessation
-
2010
- 2010-11-11 HR HR20100610T patent/HRP20100610T1/hr unknown
- 2010-11-25 CY CY20101101080T patent/CY1110953T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
EA200870177A1 (ru) | 2009-02-27 |
RS51792B (en) | 2011-12-31 |
EP1981908A2 (en) | 2008-10-22 |
PT1981908E (pt) | 2010-11-23 |
CN101370825A (zh) | 2009-02-18 |
PL1981908T3 (pl) | 2011-04-29 |
CN101370825B (zh) | 2012-10-10 |
ATE487738T1 (de) | 2010-11-15 |
SI1981908T1 (sl) | 2011-01-31 |
AU2007207697A1 (en) | 2007-07-26 |
WO2007084441A2 (en) | 2007-07-26 |
WO2007084441A3 (en) | 2007-09-07 |
EP1981908B1 (en) | 2010-11-10 |
ZA200805194B (en) | 2009-10-28 |
BRPI0706628A2 (pt) | 2011-04-05 |
US20080280832A1 (en) | 2008-11-13 |
EA013974B1 (ru) | 2010-08-30 |
IL192547A0 (en) | 2009-02-11 |
JP2009523445A (ja) | 2009-06-25 |
KR20080094697A (ko) | 2008-10-23 |
IL192547A (en) | 2012-04-30 |
DK1981908T3 (da) | 2010-12-13 |
AU2007207697B2 (en) | 2012-01-19 |
AU2007207697A2 (en) | 2008-07-31 |
DE602007010425D1 (de) | 2010-12-23 |
US7956034B2 (en) | 2011-06-07 |
CY1110953T1 (el) | 2015-06-11 |
HRP20100610T1 (hr) | 2010-12-31 |
CA2633844A1 (en) | 2007-07-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |