PL1981908T3 - Nowe D3N warianty glikolizacji FSH - Google Patents

Nowe D3N warianty glikolizacji FSH

Info

Publication number
PL1981908T3
PL1981908T3 PL07716617T PL07716617T PL1981908T3 PL 1981908 T3 PL1981908 T3 PL 1981908T3 PL 07716617 T PL07716617 T PL 07716617T PL 07716617 T PL07716617 T PL 07716617T PL 1981908 T3 PL1981908 T3 PL 1981908T3
Authority
PL
Poland
Prior art keywords
glycosylation variant
novel
fsh glycosylation
novel fsh
variant
Prior art date
Application number
PL07716617T
Other languages
English (en)
Inventor
Marco Muda
Xuliang Jiang
Sean D Mckenna
Original Assignee
Merck Serono Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Serono Sa filed Critical Merck Serono Sa
Publication of PL1981908T3 publication Critical patent/PL1981908T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/59Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/24Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL07716617T 2006-01-17 2007-01-16 Nowe D3N warianty glikolizacji FSH PL1981908T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US75948606P 2006-01-17 2006-01-17
PCT/US2007/001004 WO2007084441A2 (en) 2006-01-17 2007-01-16 Novel fsh glycosylation variant d3n
EP07716617A EP1981908B1 (en) 2006-01-17 2007-01-16 Novel fsh glycosylation variant d3n

Publications (1)

Publication Number Publication Date
PL1981908T3 true PL1981908T3 (pl) 2011-04-29

Family

ID=38163618

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07716617T PL1981908T3 (pl) 2006-01-17 2007-01-16 Nowe D3N warianty glikolizacji FSH

Country Status (22)

Country Link
US (1) US7956034B2 (pl)
EP (1) EP1981908B1 (pl)
JP (1) JP2009523445A (pl)
KR (1) KR20080094697A (pl)
CN (1) CN101370825B (pl)
AR (1) AR059054A1 (pl)
AT (1) ATE487738T1 (pl)
AU (1) AU2007207697B2 (pl)
BR (1) BRPI0706628A2 (pl)
CA (1) CA2633844A1 (pl)
CY (1) CY1110953T1 (pl)
DE (1) DE602007010425D1 (pl)
DK (1) DK1981908T3 (pl)
EA (1) EA013974B1 (pl)
HR (1) HRP20100610T1 (pl)
IL (1) IL192547A (pl)
PL (1) PL1981908T3 (pl)
PT (1) PT1981908E (pl)
RS (1) RS51792B (pl)
SI (1) SI1981908T1 (pl)
WO (1) WO2007084441A2 (pl)
ZA (1) ZA200805194B (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LT1917276T (lt) * 2005-08-26 2018-05-25 Ares Trading S.A. Glikozilinto interferono beta gavimo būdas
WO2007065918A2 (en) 2005-12-09 2007-06-14 Ares Trading S.A. Method for purifying fsh or a fsh mutant
EA013975B1 (ru) * 2005-12-22 2010-08-30 Мерк Сероно С.А. Мутантный fsh и способы его применения
US20100249381A1 (en) * 2007-10-22 2010-09-30 David Delvaille Method for Purifying FC-Fusion Proteins
AU2008314689A1 (en) * 2007-10-22 2009-04-30 Merck Serono S.A. Method for purifying an Fc-containing protein

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL133686A0 (en) * 1997-06-25 2001-04-30 Applied Research Systems Glycoprotein hormone analogs, their preparation and use
WO2001058493A1 (en) * 2000-02-11 2001-08-16 Maxygen Aps Conjugates of follicle stimulating hormones
WO2004050679A2 (en) 2001-10-22 2004-06-17 Applied Research Systems Ars Holding N.V. Mutant glycoproteins
UA88879C2 (en) * 2003-09-02 2009-12-10 Эплайд Рисерч Системз Эрс Холдинг Н.В. Fsh glycosylation mutant
WO2007065918A2 (en) * 2005-12-09 2007-06-14 Ares Trading S.A. Method for purifying fsh or a fsh mutant

Also Published As

Publication number Publication date
EP1981908B1 (en) 2010-11-10
IL192547A (en) 2012-04-30
JP2009523445A (ja) 2009-06-25
US7956034B2 (en) 2011-06-07
RS51792B (en) 2011-12-31
CN101370825A (zh) 2009-02-18
CY1110953T1 (el) 2015-06-11
IL192547A0 (en) 2009-02-11
WO2007084441A3 (en) 2007-09-07
AU2007207697A1 (en) 2007-07-26
AU2007207697B2 (en) 2012-01-19
EP1981908A2 (en) 2008-10-22
HRP20100610T1 (hr) 2010-12-31
CN101370825B (zh) 2012-10-10
SI1981908T1 (sl) 2011-01-31
BRPI0706628A2 (pt) 2011-04-05
DE602007010425D1 (de) 2010-12-23
US20080280832A1 (en) 2008-11-13
KR20080094697A (ko) 2008-10-23
EA200870177A1 (ru) 2009-02-27
AU2007207697A2 (en) 2008-07-31
ATE487738T1 (de) 2010-11-15
PT1981908E (pt) 2010-11-23
DK1981908T3 (da) 2010-12-13
WO2007084441A2 (en) 2007-07-26
CA2633844A1 (en) 2007-07-26
ZA200805194B (en) 2009-10-28
EA013974B1 (ru) 2010-08-30
AR059054A1 (es) 2008-03-12

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