DK1981908T3 - Ny FSH-glykosyleringsvariant D3N - Google Patents

Ny FSH-glykosyleringsvariant D3N

Info

Publication number
DK1981908T3
DK1981908T3 DK07716617.1T DK07716617T DK1981908T3 DK 1981908 T3 DK1981908 T3 DK 1981908T3 DK 07716617 T DK07716617 T DK 07716617T DK 1981908 T3 DK1981908 T3 DK 1981908T3
Authority
DK
Denmark
Prior art keywords
glycosylation variant
new
fsh glycosylation
new fsh
variant
Prior art date
Application number
DK07716617.1T
Other languages
English (en)
Inventor
Marco Muda
Xuliang Jiang
Sean D Mckenna
Original Assignee
Merck Serono Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Serono Sa filed Critical Merck Serono Sa
Application granted granted Critical
Publication of DK1981908T3 publication Critical patent/DK1981908T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/59Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/24Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK07716617.1T 2006-01-17 2007-01-16 Ny FSH-glykosyleringsvariant D3N DK1981908T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75948606P 2006-01-17 2006-01-17
PCT/US2007/001004 WO2007084441A2 (en) 2006-01-17 2007-01-16 Novel fsh glycosylation variant d3n

Publications (1)

Publication Number Publication Date
DK1981908T3 true DK1981908T3 (da) 2010-12-13

Family

ID=38163618

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07716617.1T DK1981908T3 (da) 2006-01-17 2007-01-16 Ny FSH-glykosyleringsvariant D3N

Country Status (22)

Country Link
US (1) US7956034B2 (da)
EP (1) EP1981908B1 (da)
JP (1) JP2009523445A (da)
KR (1) KR20080094697A (da)
CN (1) CN101370825B (da)
AR (1) AR059054A1 (da)
AT (1) ATE487738T1 (da)
AU (1) AU2007207697B2 (da)
BR (1) BRPI0706628A2 (da)
CA (1) CA2633844A1 (da)
CY (1) CY1110953T1 (da)
DE (1) DE602007010425D1 (da)
DK (1) DK1981908T3 (da)
EA (1) EA013974B1 (da)
HR (1) HRP20100610T1 (da)
IL (1) IL192547A (da)
PL (1) PL1981908T3 (da)
PT (1) PT1981908E (da)
RS (1) RS51792B (da)
SI (1) SI1981908T1 (da)
WO (1) WO2007084441A2 (da)
ZA (1) ZA200805194B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS57549B1 (sr) 2005-08-26 2018-10-31 Ares Trading Sa Proces za pripremu glikoziliranog interferona beta
EP1960419B1 (en) * 2005-12-09 2016-03-16 Ares Trading S.A. Method for purifying fsh or a fsh mutant
JP5249044B2 (ja) 2005-12-22 2013-07-31 メルク セローノ ソシエテ アノニム Fsh突然変異体
WO2009053358A1 (en) * 2007-10-22 2009-04-30 Merck Serono S.A. Method for purifying fc-fusion proteins
US20100256337A1 (en) * 2007-10-22 2010-10-07 Merck Serono Sa Method for purifying an fc-containing protein

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2268781T3 (es) * 1997-06-25 2007-03-16 Applied Research Systems Ars Holding N.V. Analogos de hormonas glicoproteinicas reticuladas con disulfuro, su preparacion y uso.
AU2001231531A1 (en) 2000-02-11 2001-08-20 Maxygen Aps Follicle stimulating hormones
ES2389835T3 (es) * 2001-10-22 2012-11-02 Merck Serono Sa Glicoproteínas mutantes
UA88879C2 (en) * 2003-09-02 2009-12-10 Эплайд Рисерч Системз Эрс Холдинг Н.В. Fsh glycosylation mutant
EP1960419B1 (en) * 2005-12-09 2016-03-16 Ares Trading S.A. Method for purifying fsh or a fsh mutant

Also Published As

Publication number Publication date
AU2007207697A1 (en) 2007-07-26
BRPI0706628A2 (pt) 2011-04-05
US7956034B2 (en) 2011-06-07
CA2633844A1 (en) 2007-07-26
IL192547A0 (en) 2009-02-11
KR20080094697A (ko) 2008-10-23
EP1981908A2 (en) 2008-10-22
AU2007207697A2 (en) 2008-07-31
WO2007084441A2 (en) 2007-07-26
AR059054A1 (es) 2008-03-12
IL192547A (en) 2012-04-30
AU2007207697B2 (en) 2012-01-19
PL1981908T3 (pl) 2011-04-29
RS51792B (sr) 2011-12-31
CN101370825B (zh) 2012-10-10
WO2007084441A3 (en) 2007-09-07
SI1981908T1 (sl) 2011-01-31
JP2009523445A (ja) 2009-06-25
EA200870177A1 (ru) 2009-02-27
ZA200805194B (en) 2009-10-28
CN101370825A (zh) 2009-02-18
US20080280832A1 (en) 2008-11-13
EA013974B1 (ru) 2010-08-30
HRP20100610T1 (hr) 2010-12-31
EP1981908B1 (en) 2010-11-10
ATE487738T1 (de) 2010-11-15
CY1110953T1 (el) 2015-06-11
PT1981908E (pt) 2010-11-23
DE602007010425D1 (de) 2010-12-23

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