ATE535603T1 - Mutante reverse transkriptase und verwendungsverfahren - Google Patents
Mutante reverse transkriptase und verwendungsverfahrenInfo
- Publication number
- ATE535603T1 ATE535603T1 AT06801382T AT06801382T ATE535603T1 AT E535603 T1 ATE535603 T1 AT E535603T1 AT 06801382 T AT06801382 T AT 06801382T AT 06801382 T AT06801382 T AT 06801382T AT E535603 T1 ATE535603 T1 AT E535603T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- transcriptasis
- mutant reverse
- reverse transcriptase
- mmlv reverse
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
- C12Y207/07049—RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1276—RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Enzymes And Modification Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70701905P | 2005-08-10 | 2005-08-10 | |
PCT/US2006/031567 WO2007022045A2 (en) | 2005-08-10 | 2006-08-10 | Mutant reverse transcriptase and methods of use |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE535603T1 true ATE535603T1 (de) | 2011-12-15 |
Family
ID=37758252
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06801382T ATE535603T1 (de) | 2005-08-10 | 2006-08-10 | Mutante reverse transkriptase und verwendungsverfahren |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1931772B1 (de) |
JP (1) | JP5203200B2 (de) |
AT (1) | ATE535603T1 (de) |
CA (1) | CA2617790A1 (de) |
WO (1) | WO2007022045A2 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0806562D0 (en) * | 2008-04-10 | 2008-05-14 | Fermentas Uab | Production of nucleic acid |
EP2604688B1 (de) * | 2010-08-13 | 2018-01-10 | Kyoto University | Variante reverse transkriptase |
KR101818126B1 (ko) * | 2011-02-09 | 2018-01-15 | (주)바이오니아 | 열안정성이 증가된 역전사효소 |
ES2525135B1 (es) * | 2013-05-17 | 2015-09-29 | Consejo Superior De Investigaciones Científicas (Csic) | Retrotranscriptasas del vih tipo 1 grupo o, activas a temperaturas elevadas |
WO2015112767A2 (en) * | 2014-01-22 | 2015-07-30 | Life Technologies Corporation | Novel reverse transcriptases for use in high temperature nucleic acid synthesis |
CN106414704B (zh) | 2014-03-14 | 2020-11-03 | 生命技术公司 | 用于核酸扩增和检测的集成系统 |
US11046940B2 (en) | 2016-04-12 | 2021-06-29 | Solis Biodyne Ou | Synthetic reverse transcriptases and uses thereof |
WO2018110595A1 (ja) | 2016-12-14 | 2018-06-21 | タカラバイオ株式会社 | 耐熱性の逆転写酵素変異体 |
CN110637084A (zh) * | 2017-04-26 | 2019-12-31 | 10X基因组学有限公司 | Mmlv逆转录酶变体 |
US20180312822A1 (en) * | 2017-04-26 | 2018-11-01 | 10X Genomics, Inc. | Mmlv reverse transcriptase variants |
WO2020132966A1 (zh) * | 2018-12-26 | 2020-07-02 | 深圳华大生命科学研究院 | 酶活性提高的逆转录酶及其应用 |
CN112795551B (zh) * | 2019-11-13 | 2024-01-30 | 广州达安基因股份有限公司 | 一种耐高温逆转录酶突变体及其应用 |
CN112795550B (zh) * | 2019-11-13 | 2024-05-31 | 广州达安基因股份有限公司 | 耐高温逆转录酶突变体 |
WO2021119320A2 (en) | 2019-12-11 | 2021-06-17 | 10X Genomics, Inc. | Reverse transcriptase variants |
WO2022265965A1 (en) * | 2021-06-14 | 2022-12-22 | 10X Genomics, Inc. | Reverse transcriptase variants for improved performance |
WO2023114473A2 (en) * | 2021-12-16 | 2023-06-22 | 10X Genomics, Inc. | Recombinant reverse transcriptase variants for improved performance |
CN114317485B (zh) * | 2021-12-30 | 2023-04-11 | 南京巨匠生物科技有限公司 | 重组鼠白血病病毒逆转录酶突变体、制备方法及应用 |
WO2023164726A2 (en) * | 2022-02-28 | 2023-08-31 | Integrated Dna Technologies, Inc. | C-terminal peptide extensions with increased activity |
CN115261352B (zh) * | 2022-06-08 | 2024-03-29 | 厦门通灵生物医药科技有限公司 | 一种耐高温的突变型逆转录酶及其制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4193079B2 (ja) * | 1998-11-10 | 2008-12-10 | 東洋紡績株式会社 | 変異型逆転写酵素 |
AU2001247413B2 (en) * | 2000-03-15 | 2005-08-25 | Invitrogen Corporation | High fidelity reverse transcriptases and uses thereof |
WO2001092500A1 (en) * | 2000-05-26 | 2001-12-06 | Invitrogen Corporation | Thermostable reverse transcriptases and uses thereof |
US20040209276A1 (en) * | 2002-09-13 | 2004-10-21 | Smith Michael D. | Thermostable reverse transcriptases and uses thereof |
CN100537756C (zh) * | 2004-01-13 | 2009-09-09 | 中国科学院生物物理研究所 | 重组小鼠白血病病毒逆转录酶及其编码基因与表达方法 |
-
2006
- 2006-08-10 AT AT06801382T patent/ATE535603T1/de active
- 2006-08-10 EP EP06801382A patent/EP1931772B1/de active Active
- 2006-08-10 WO PCT/US2006/031567 patent/WO2007022045A2/en active Application Filing
- 2006-08-10 CA CA002617790A patent/CA2617790A1/en not_active Abandoned
- 2006-08-10 JP JP2008526271A patent/JP5203200B2/ja active Active
Also Published As
Publication number | Publication date |
---|---|
JP5203200B2 (ja) | 2013-06-05 |
WO2007022045A3 (en) | 2009-05-22 |
WO2007022045A2 (en) | 2007-02-22 |
CA2617790A1 (en) | 2007-02-22 |
EP1931772A2 (de) | 2008-06-18 |
EP1931772A4 (de) | 2009-12-30 |
EP1931772B1 (de) | 2011-11-30 |
JP2009504162A (ja) | 2009-02-05 |
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