HRP20100159T1 - Upotreba hidrofilnog matriksa koji se sastoji od derivata poliakrilne kiseline, celuloznog etera i sredstva za raspadanje u proizvodnji medikamenta za liječenje ženskih genitalnih poremećaja - Google Patents
Upotreba hidrofilnog matriksa koji se sastoji od derivata poliakrilne kiseline, celuloznog etera i sredstva za raspadanje u proizvodnji medikamenta za liječenje ženskih genitalnih poremećaja Download PDFInfo
- Publication number
- HRP20100159T1 HRP20100159T1 HR20100159T HRP20100159T HRP20100159T1 HR P20100159 T1 HRP20100159 T1 HR P20100159T1 HR 20100159 T HR20100159 T HR 20100159T HR P20100159 T HRP20100159 T HR P20100159T HR P20100159 T1 HRP20100159 T1 HR P20100159T1
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- Prior art keywords
- use according
- polyacrylic acid
- starches
- matrix
- disintegrant
- Prior art date
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- 239000011159 matrix material Substances 0.000 title claims abstract 11
- 229920002125 Sokalan® Polymers 0.000 title claims abstract 10
- 239000004584 polyacrylic acid Substances 0.000 title claims abstract 9
- 229920003086 cellulose ether Polymers 0.000 title claims abstract 6
- 239000007884 disintegrant Substances 0.000 title claims abstract 6
- 208000017443 reproductive system disease Diseases 0.000 title claims abstract 4
- 238000004519 manufacturing process Methods 0.000 title claims abstract 3
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- 238000009472 formulation Methods 0.000 claims abstract 8
- 239000000203 mixture Substances 0.000 claims abstract 8
- 235000019698 starch Nutrition 0.000 claims abstract 8
- 210000004392 genitalia Anatomy 0.000 claims abstract 5
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- 239000000661 sodium alginate Substances 0.000 claims abstract 2
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- RJKFOVLPORLFTN-LEKSSAKUSA-N Progesterone Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H](C(=O)C)[C@@]1(C)CC2 RJKFOVLPORLFTN-LEKSSAKUSA-N 0.000 claims 2
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- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical group OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims 1
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- SRQKTCXJCCHINN-NYYWCZLTSA-N nifuratel Chemical compound O=C1OC(CSC)CN1\N=C\C1=CC=C([N+]([O-])=O)O1 SRQKTCXJCCHINN-NYYWCZLTSA-N 0.000 claims 1
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Classifications
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Inorganic Chemistry (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06116269A EP1872775A1 (en) | 2006-06-29 | 2006-06-29 | Use of a hydrophilic matrix comprising a polyacrylic acid derivative, a cellulose ether and a disintegrant for the manufacture of a medicament for treating female genital disorders |
| PCT/EP2007/056185 WO2008000683A1 (en) | 2006-06-29 | 2007-06-21 | Use of a hydrophilic matrix comprising a polyacrylic acid derivative, a cellulose ether and a disintegrant for the manufacture of a medicament for treating female genital disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20100159T1 true HRP20100159T1 (hr) | 2010-05-31 |
Family
ID=37433668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20100159T HRP20100159T1 (hr) | 2006-06-29 | 2010-03-18 | Upotreba hidrofilnog matriksa koji se sastoji od derivata poliakrilne kiseline, celuloznog etera i sredstva za raspadanje u proizvodnji medikamenta za liječenje ženskih genitalnih poremećaja |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US8865201B2 (ru) |
| EP (2) | EP1872775A1 (ru) |
| JP (1) | JP5205374B2 (ru) |
| KR (1) | KR101443149B1 (ru) |
| CN (2) | CN101478951A (ru) |
| AR (1) | AR061771A1 (ru) |
| AT (1) | ATE455534T1 (ru) |
| BR (1) | BRPI0713298A2 (ru) |
| CA (1) | CA2652226C (ru) |
| CO (1) | CO6140022A2 (ru) |
| CY (1) | CY1109910T1 (ru) |
| DE (1) | DE602007004486D1 (ru) |
| DK (1) | DK2032123T3 (ru) |
| EA (1) | EA018257B1 (ru) |
| ES (1) | ES2339069T3 (ru) |
| HK (1) | HK1128587A1 (ru) |
| HR (1) | HRP20100159T1 (ru) |
| MA (1) | MA30597B1 (ru) |
| MX (1) | MX2008016508A (ru) |
| NO (1) | NO20090095L (ru) |
| PL (1) | PL2032123T3 (ru) |
| PT (1) | PT2032123E (ru) |
| RS (1) | RS51279B (ru) |
| SI (1) | SI2032123T1 (ru) |
| WO (1) | WO2008000683A1 (ru) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2344673B1 (es) | 2008-08-07 | 2011-05-03 | Italfarmaco, S.A. | Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral. |
| EP2163240A1 (en) * | 2008-09-12 | 2010-03-17 | Universita' Degli Studi Di Genova | A method for the production of bioadhesive compact matrices |
| CN102202648B (zh) * | 2008-10-23 | 2014-07-23 | 汉高公司 | 包含脱支淀粉的阴道小丸 |
| ES2344675B1 (es) * | 2008-12-19 | 2011-04-28 | Italfarmaco, S.A. | Uso de estriol en la preparacion de una formulacion farrmaceutica para el tratamiento de atrofia vaginal en mujeres con riesgo de patologiacardiovascular. |
| EP2243482A1 (en) * | 2009-04-20 | 2010-10-27 | Polichem SA | Use of nifuratel to treat infections caused by atopobium species |
| LT2782584T (lt) | 2011-11-23 | 2021-09-10 | Therapeuticsmd, Inc. | Natūralios kombinuotos pakaitinės hormonų terapijos kompozicijos ir gydymas |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| AU2014349132A1 (en) * | 2013-10-22 | 2016-04-14 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositons and methods |
| AU2015264003A1 (en) | 2014-05-22 | 2016-11-17 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| CN105796520A (zh) * | 2014-12-29 | 2016-07-27 | 四川滇虹医药开发有限公司 | 一种缓释型硝酸布康唑直压片剂及其制备方法 |
| CN107735083B (zh) | 2015-01-23 | 2021-06-29 | 拜奥斯迪姆知识产权控股公司 | 抗菌组合物 |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| WO2017173071A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| MX2019004238A (es) * | 2016-10-13 | 2019-11-08 | Catalent Uk Swindon Zydis Ltd | Composiciones farmaceuticas liofilizadas para suministro vaginal. |
| GB201808567D0 (en) * | 2018-05-24 | 2018-07-11 | Douglas Pharmaceuticals Ltd | Pharmaceutical compositions |
| CN109010320B (zh) * | 2018-09-18 | 2021-09-14 | 浙江汇能生物股份有限公司 | 一种双释型聚卡波非钙颗粒剂及制备方法和畜禽中的应用 |
| CN114129530A (zh) * | 2021-12-08 | 2022-03-04 | 南京康川济医药科技有限公司 | 一种黄体酮缓释组合物及其制备方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2096744A (en) | 1932-10-27 | 1937-10-26 | Schering Corp | Hydrogenation products of follicle hormones and method of producing same |
| US2232438A (en) | 1934-08-04 | 1941-02-18 | Schering Corp | Unsaturated pregnanolones and pregnandiones and a method of producing the same |
| US2243887A (en) | 1935-11-09 | 1941-06-03 | Schering Corp | Tertiary carbinols of the cyclopentano-polyhydrophenanthrene series and a method of producing the same |
| US2251939A (en) | 1935-11-22 | 1941-08-12 | Schering Corp | Tertiary alcohols of the cyclopentano polyhydro phenanthrene series and a method of producing the same |
| US2379832A (en) | 1936-06-02 | 1945-07-03 | Schering Corp | Process for the manufacture of unsaturated ketones of the cyclopentano polyhydro phenanthrene series |
| CH202847A (de) | 1937-06-26 | 1939-02-15 | Chem Ind Basel | Verfahren zur Darstellung von Acetylen-Derivaten der Cyclopentanopolyhydrophenanthren-Reihe. |
| US2265976A (en) | 1937-10-25 | 1941-12-09 | Schering Corp | Tertiary alcohols of the estrane series and their derivatives and a process for their manufacture |
| US2314185A (en) | 1939-09-01 | 1943-03-16 | Zondek Bernhard | Process for the manufacture of progesterone |
| BE665514A (ru) | 1964-06-16 | |||
| NL146838B (nl) | 1966-06-24 | 1975-08-15 | Organon Nv | Werkwijze voor het bereiden van (delta)5(10)-3- keto-19-norsteroiden. |
| JPS5562012A (en) * | 1978-11-06 | 1980-05-10 | Teijin Ltd | Slow-releasing preparation |
| US6416779B1 (en) * | 1997-06-11 | 2002-07-09 | Umd, Inc. | Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections |
| US7744916B2 (en) * | 1997-06-11 | 2010-06-29 | Umd, Inc. | Coated vaginal device for delivery of anti-migraine and anti-nausea drugs |
| US6248358B1 (en) | 1998-08-25 | 2001-06-19 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets and methods of making and using the same |
| UA74168C2 (ru) | 1999-10-05 | 2005-11-15 | Коламбіа Леборетеріс (Бермуда) Лімітед | Лечение эндометриоза, лечение бесплодия или повышение фертильности при применении лекарственного средства на основе бета-адренэргического агониста |
| JP2004501190A (ja) * | 2000-06-23 | 2004-01-15 | テバ ファーマシューティカル インダストリーズ リミティド | 治療薬の胃部保留および制御された放出のための急速膨張する組成物とその組成物を含む剤形 |
| FR2813865B1 (fr) | 2000-09-08 | 2002-12-20 | Rexam Sofab | Dispositif a buse unique pour la distribution selective de deux produits |
| EP1318790A4 (en) * | 2000-09-19 | 2006-02-01 | Cima Labs Inc | PHARMACEUTICAL COMPOSITIONS FOR RECTAL AND VAGINAL ADMINISTRATION |
| CN1536986B (zh) * | 2001-03-27 | 2012-07-04 | 沃纳奇尔科特(爱尔兰)有限公司 | 用于抗微生物剂给药的阴道内药物递送装置 |
| US6899890B2 (en) * | 2002-03-20 | 2005-05-31 | Kv Pharmaceutical Company | Bioadhesive drug delivery system |
| CN1302764C (zh) | 2005-01-10 | 2007-03-07 | 凌沛学 | 一种妇科用药阴道凝胶片 |
-
2006
- 2006-06-29 EP EP06116269A patent/EP1872775A1/en not_active Withdrawn
-
2007
- 2007-06-21 AT AT07730288T patent/ATE455534T1/de active
- 2007-06-21 CN CNA2007800239858A patent/CN101478951A/zh active Pending
- 2007-06-21 DE DE602007004486T patent/DE602007004486D1/de active Active
- 2007-06-21 US US12/308,786 patent/US8865201B2/en not_active Expired - Fee Related
- 2007-06-21 JP JP2009517127A patent/JP5205374B2/ja not_active Expired - Fee Related
- 2007-06-21 RS RSP-2010/0045A patent/RS51279B/sr unknown
- 2007-06-21 BR BRPI0713298-0A patent/BRPI0713298A2/pt not_active IP Right Cessation
- 2007-06-21 CA CA2652226A patent/CA2652226C/en not_active Expired - Fee Related
- 2007-06-21 ES ES07730288T patent/ES2339069T3/es active Active
- 2007-06-21 EA EA200900087A patent/EA018257B1/ru not_active IP Right Cessation
- 2007-06-21 SI SI200730193T patent/SI2032123T1/sl unknown
- 2007-06-21 CN CN2013100083584A patent/CN103071157A/zh active Pending
- 2007-06-21 MX MX2008016508A patent/MX2008016508A/es active IP Right Grant
- 2007-06-21 WO PCT/EP2007/056185 patent/WO2008000683A1/en active Application Filing
- 2007-06-21 PL PL07730288T patent/PL2032123T3/pl unknown
- 2007-06-21 PT PT07730288T patent/PT2032123E/pt unknown
- 2007-06-21 KR KR1020087032076A patent/KR101443149B1/ko not_active IP Right Cessation
- 2007-06-21 EP EP07730288A patent/EP2032123B1/en active Active
- 2007-06-21 DK DK07730288.3T patent/DK2032123T3/da active
- 2007-06-29 AR ARP070102948A patent/AR061771A1/es unknown
-
2008
- 2008-12-24 CO CO08136879A patent/CO6140022A2/es unknown
-
2009
- 2009-01-07 NO NO20090095A patent/NO20090095L/no not_active Application Discontinuation
- 2009-01-22 MA MA31583A patent/MA30597B1/fr unknown
- 2009-05-05 HK HK09104134.0A patent/HK1128587A1/xx not_active IP Right Cessation
-
2010
- 2010-03-18 HR HR20100159T patent/HRP20100159T1/hr unknown
- 2010-03-19 CY CY20101100256T patent/CY1109910T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK2032123T3 (da) | 2010-03-08 |
| PT2032123E (pt) | 2010-04-07 |
| KR20090033341A (ko) | 2009-04-02 |
| EA018257B1 (ru) | 2013-06-28 |
| DE602007004486D1 (de) | 2010-03-11 |
| JP5205374B2 (ja) | 2013-06-05 |
| CN101478951A (zh) | 2009-07-08 |
| MX2008016508A (es) | 2009-04-22 |
| KR101443149B1 (ko) | 2014-09-23 |
| CA2652226A1 (en) | 2008-01-03 |
| EP2032123B1 (en) | 2010-01-20 |
| JP2009541419A (ja) | 2009-11-26 |
| AR061771A1 (es) | 2008-09-17 |
| EP1872775A1 (en) | 2008-01-02 |
| CA2652226C (en) | 2014-08-12 |
| US8865201B2 (en) | 2014-10-21 |
| ES2339069T3 (es) | 2010-05-14 |
| CN103071157A (zh) | 2013-05-01 |
| EA200900087A1 (ru) | 2009-06-30 |
| US20110091555A1 (en) | 2011-04-21 |
| EP2032123A1 (en) | 2009-03-11 |
| NO20090095L (no) | 2009-01-07 |
| WO2008000683A1 (en) | 2008-01-03 |
| PL2032123T3 (pl) | 2010-06-30 |
| SI2032123T1 (sl) | 2010-04-30 |
| CY1109910T1 (el) | 2014-09-10 |
| HK1128587A1 (en) | 2009-10-30 |
| RS51279B (sr) | 2010-12-31 |
| CO6140022A2 (es) | 2010-03-19 |
| MA30597B1 (fr) | 2009-07-01 |
| BRPI0713298A2 (pt) | 2012-04-17 |
| ATE455534T1 (de) | 2010-02-15 |
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