MX2008016508A - Uso de una matriz hidrofilica que contiene un derivado de acido poliacrilico, un eter de celulosa y un desintegrante para la elaboracion de un medicamento para tratar trastornos genitales femeninos. - Google Patents
Uso de una matriz hidrofilica que contiene un derivado de acido poliacrilico, un eter de celulosa y un desintegrante para la elaboracion de un medicamento para tratar trastornos genitales femeninos.Info
- Publication number
- MX2008016508A MX2008016508A MX2008016508A MX2008016508A MX2008016508A MX 2008016508 A MX2008016508 A MX 2008016508A MX 2008016508 A MX2008016508 A MX 2008016508A MX 2008016508 A MX2008016508 A MX 2008016508A MX 2008016508 A MX2008016508 A MX 2008016508A
- Authority
- MX
- Mexico
- Prior art keywords
- disintegrant
- acid derivative
- polyacrylic acid
- cellulose ether
- matrix
- Prior art date
Links
- 239000011159 matrix material Substances 0.000 title abstract 5
- 229920002125 Sokalan® Polymers 0.000 title abstract 2
- 229920003086 cellulose ether Polymers 0.000 title abstract 2
- 239000007884 disintegrant Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000004584 polyacrylic acid Substances 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 208000017443 reproductive system disease Diseases 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 239000007787 solid Substances 0.000 abstract 2
- 208000004926 Bacterial Vaginosis Diseases 0.000 abstract 1
- 208000005448 Trichomonas Infections Diseases 0.000 abstract 1
- 206010044620 Trichomoniasis Diseases 0.000 abstract 1
- 208000037009 Vaginitis bacterial Diseases 0.000 abstract 1
- 201000007096 Vulvovaginal Candidiasis Diseases 0.000 abstract 1
- 239000000227 bioadhesive Substances 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 208000013464 vaginal disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/02—Local antiseptics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Gynecology & Obstetrics (AREA)
- Urology & Nephrology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Una matriz hidrofilica es mostrada, la cual comprende: a) al menos un derivado de ácido poliacrilico en cantidades preferidas de 0.5-40%, b) al menos un éter celulosa en cantidades preferidas de 30-90% y c) al menos un desintegrante en cantidades preferidas de 2-50%, con relación al peso de la matriz. La matriz es utilizada en combinación con al menos un principio activo farmacéuticamente aceptable para elaboración de formulaciones de liberación controlada de bioadhesivo sólido para el tratamiento de disfunciones vaginales, tales como candidiasis vulvovaginal, vaginosis bacterial o tricomoniasis. La matriz es utilizada en formulaciones sólidas en cantidades de aproximadamente 5-60%, preferiblemente 20-40%, y el principio activo en cantidades de aproximadamente 2-70%, preferiblemente 5-50% con relación al peso de la formulación.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06116269A EP1872775A1 (en) | 2006-06-29 | 2006-06-29 | Use of a hydrophilic matrix comprising a polyacrylic acid derivative, a cellulose ether and a disintegrant for the manufacture of a medicament for treating female genital disorders |
| PCT/EP2007/056185 WO2008000683A1 (en) | 2006-06-29 | 2007-06-21 | Use of a hydrophilic matrix comprising a polyacrylic acid derivative, a cellulose ether and a disintegrant for the manufacture of a medicament for treating female genital disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2008016508A true MX2008016508A (es) | 2009-04-22 |
Family
ID=37433668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2008016508A MX2008016508A (es) | 2006-06-29 | 2007-06-21 | Uso de una matriz hidrofilica que contiene un derivado de acido poliacrilico, un eter de celulosa y un desintegrante para la elaboracion de un medicamento para tratar trastornos genitales femeninos. |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US8865201B2 (es) |
| EP (2) | EP1872775A1 (es) |
| JP (1) | JP5205374B2 (es) |
| KR (1) | KR101443149B1 (es) |
| CN (2) | CN101478951A (es) |
| AR (1) | AR061771A1 (es) |
| AT (1) | ATE455534T1 (es) |
| BR (1) | BRPI0713298A2 (es) |
| CA (1) | CA2652226C (es) |
| CO (1) | CO6140022A2 (es) |
| CY (1) | CY1109910T1 (es) |
| DE (1) | DE602007004486D1 (es) |
| DK (1) | DK2032123T3 (es) |
| EA (1) | EA018257B1 (es) |
| ES (1) | ES2339069T3 (es) |
| HK (1) | HK1128587A1 (es) |
| HR (1) | HRP20100159T1 (es) |
| MA (1) | MA30597B1 (es) |
| MX (1) | MX2008016508A (es) |
| NO (1) | NO20090095L (es) |
| PL (1) | PL2032123T3 (es) |
| PT (1) | PT2032123E (es) |
| RS (1) | RS51279B (es) |
| SI (1) | SI2032123T1 (es) |
| WO (1) | WO2008000683A1 (es) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2344673B1 (es) | 2008-08-07 | 2011-05-03 | Italfarmaco, S.A. | Uso de estriol en la preparacion de una formulacion farmaceutica parael tratamiento de atrofia vaginal en mujeres con riesgo de potologiatumoral. |
| EP2163240A1 (en) * | 2008-09-12 | 2010-03-17 | Universita' Degli Studi Di Genova | A method for the production of bioadhesive compact matrices |
| RU2519715C2 (ru) * | 2008-10-23 | 2014-06-20 | Хенкель Корпорейшн | Фармацевтические гранулы, содержащие модифицированный крахмал, и их терапевтические применения |
| ES2344675B1 (es) * | 2008-12-19 | 2011-04-28 | Italfarmaco, S.A. | Uso de estriol en la preparacion de una formulacion farrmaceutica para el tratamiento de atrofia vaginal en mujeres con riesgo de patologiacardiovascular. |
| EP2243482A1 (en) * | 2009-04-20 | 2010-10-27 | Polichem SA | Use of nifuratel to treat infections caused by atopobium species |
| PT2782584T (pt) | 2011-11-23 | 2021-09-02 | Therapeuticsmd Inc | Preparações e terapias de substituição para hormonoterapias naturais combinadas |
| US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
| US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
| US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
| US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
| US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
| AU2014349132A1 (en) * | 2013-10-22 | 2016-04-14 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositons and methods |
| RU2016143081A (ru) | 2014-05-22 | 2018-06-26 | Терапьютиксмд, Инк. | Натуральные комбинированные гормонозаместительные составы и терапии |
| CN105796520A (zh) * | 2014-12-29 | 2016-07-27 | 四川滇虹医药开发有限公司 | 一种缓释型硝酸布康唑直压片剂及其制备方法 |
| CA3012227C (en) | 2015-01-23 | 2023-05-23 | Biocidium Biopharmaceuticals Inc. | Anti-bacterial compositions |
| US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
| US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
| CA3020153A1 (en) | 2016-04-01 | 2017-10-05 | Therapeuticsmd, Inc. | Steroid hormone pharmaceutical composition |
| MX2019004238A (es) * | 2016-10-13 | 2019-11-08 | Catalent Uk Swindon Zydis Ltd | Composiciones farmaceuticas liofilizadas para suministro vaginal. |
| GB201808567D0 (en) * | 2018-05-24 | 2018-07-11 | Douglas Pharmaceuticals Ltd | Pharmaceutical compositions |
| CN109010320B (zh) * | 2018-09-18 | 2021-09-14 | 浙江汇能生物股份有限公司 | 一种双释型聚卡波非钙颗粒剂及制备方法和畜禽中的应用 |
| CN114129530A (zh) * | 2021-12-08 | 2022-03-04 | 南京康川济医药科技有限公司 | 一种黄体酮缓释组合物及其制备方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2096744A (en) | 1932-10-27 | 1937-10-26 | Schering Corp | Hydrogenation products of follicle hormones and method of producing same |
| US2232438A (en) | 1934-08-04 | 1941-02-18 | Schering Corp | Unsaturated pregnanolones and pregnandiones and a method of producing the same |
| US2243887A (en) | 1935-11-09 | 1941-06-03 | Schering Corp | Tertiary carbinols of the cyclopentano-polyhydrophenanthrene series and a method of producing the same |
| US2251939A (en) | 1935-11-22 | 1941-08-12 | Schering Corp | Tertiary alcohols of the cyclopentano polyhydro phenanthrene series and a method of producing the same |
| US2379832A (en) | 1936-06-02 | 1945-07-03 | Schering Corp | Process for the manufacture of unsaturated ketones of the cyclopentano polyhydro phenanthrene series |
| CH202847A (de) | 1937-06-26 | 1939-02-15 | Chem Ind Basel | Verfahren zur Darstellung von Acetylen-Derivaten der Cyclopentanopolyhydrophenanthren-Reihe. |
| US2265976A (en) | 1937-10-25 | 1941-12-09 | Schering Corp | Tertiary alcohols of the estrane series and their derivatives and a process for their manufacture |
| US2314185A (en) | 1939-09-01 | 1943-03-16 | Zondek Bernhard | Process for the manufacture of progesterone |
| BE665514A (es) | 1964-06-16 | |||
| NL146838B (nl) | 1966-06-24 | 1975-08-15 | Organon Nv | Werkwijze voor het bereiden van (delta)5(10)-3- keto-19-norsteroiden. |
| JPS5562012A (en) * | 1978-11-06 | 1980-05-10 | Teijin Ltd | Slow-releasing preparation |
| US7744916B2 (en) * | 1997-06-11 | 2010-06-29 | Umd, Inc. | Coated vaginal device for delivery of anti-migraine and anti-nausea drugs |
| US6416779B1 (en) * | 1997-06-11 | 2002-07-09 | Umd, Inc. | Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections |
| US6248358B1 (en) | 1998-08-25 | 2001-06-19 | Columbia Laboratories, Inc. | Bioadhesive progressive hydration tablets and methods of making and using the same |
| UA74168C2 (uk) | 1999-10-05 | 2005-11-15 | Коламбіа Леборетеріс (Бермуда) Лімітед | Лікування ендометріозу або безпліддя, або покращення плідності та застосування бета-адренергічного агоніста для виробництва лікарського засобу |
| EA200300046A1 (ru) | 2000-06-23 | 2003-10-30 | Тева Фармасьютикал Индастриес Лтд. | Быстро увеличивающаяся в объеме композиция для удерживания и контролированного выделения терапевтических агентов в желудке и лекарственные формы, включающие композицию |
| FR2813865B1 (fr) | 2000-09-08 | 2002-12-20 | Rexam Sofab | Dispositif a buse unique pour la distribution selective de deux produits |
| WO2002024170A1 (en) | 2000-09-19 | 2002-03-28 | Cima Labs Inc. | Pharmaceutical compositions for rectal and vaginal administration |
| JP4959907B2 (ja) * | 2001-03-27 | 2012-06-27 | ワーナー チルコット（アイルランド）リミティド | 抗菌剤投与のための膣内用ドラッグデリバリーデバイス |
| US6899890B2 (en) * | 2002-03-20 | 2005-05-31 | Kv Pharmaceutical Company | Bioadhesive drug delivery system |
| CN1302764C (zh) * | 2005-01-10 | 2007-03-07 | 凌沛学 | 一种妇科用药阴道凝胶片 |
-
2006
- 2006-06-29 EP EP06116269A patent/EP1872775A1/en not_active Withdrawn
-
2007
- 2007-06-21 ES ES07730288T patent/ES2339069T3/es active Active
- 2007-06-21 CN CNA2007800239858A patent/CN101478951A/zh active Pending
- 2007-06-21 WO PCT/EP2007/056185 patent/WO2008000683A1/en active Application Filing
- 2007-06-21 PT PT07730288T patent/PT2032123E/pt unknown
- 2007-06-21 KR KR1020087032076A patent/KR101443149B1/ko not_active IP Right Cessation
- 2007-06-21 AT AT07730288T patent/ATE455534T1/de active
- 2007-06-21 EP EP07730288A patent/EP2032123B1/en active Active
- 2007-06-21 PL PL07730288T patent/PL2032123T3/pl unknown
- 2007-06-21 SI SI200730193T patent/SI2032123T1/sl unknown
- 2007-06-21 MX MX2008016508A patent/MX2008016508A/es active IP Right Grant
- 2007-06-21 RS RSP-2010/0045A patent/RS51279B/sr unknown
- 2007-06-21 US US12/308,786 patent/US8865201B2/en not_active Expired - Fee Related
- 2007-06-21 JP JP2009517127A patent/JP5205374B2/ja not_active Expired - Fee Related
- 2007-06-21 DE DE602007004486T patent/DE602007004486D1/de active Active
- 2007-06-21 CA CA2652226A patent/CA2652226C/en not_active Expired - Fee Related
- 2007-06-21 EA EA200900087A patent/EA018257B1/ru not_active IP Right Cessation
- 2007-06-21 BR BRPI0713298-0A patent/BRPI0713298A2/pt not_active IP Right Cessation
- 2007-06-21 CN CN2013100083584A patent/CN103071157A/zh active Pending
- 2007-06-21 DK DK07730288.3T patent/DK2032123T3/da active
- 2007-06-29 AR ARP070102948A patent/AR061771A1/es unknown
-
2008
- 2008-12-24 CO CO08136879A patent/CO6140022A2/es unknown
-
2009
- 2009-01-07 NO NO20090095A patent/NO20090095L/no not_active Application Discontinuation
- 2009-01-22 MA MA31583A patent/MA30597B1/fr unknown
- 2009-05-05 HK HK09104134.0A patent/HK1128587A1/xx not_active IP Right Cessation
-
2010
- 2010-03-18 HR HR20100159T patent/HRP20100159T1/hr unknown
- 2010-03-19 CY CY20101100256T patent/CY1109910T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2652226A1 (en) | 2008-01-03 |
| KR101443149B1 (ko) | 2014-09-23 |
| SI2032123T1 (sl) | 2010-04-30 |
| CA2652226C (en) | 2014-08-12 |
| CN101478951A (zh) | 2009-07-08 |
| US8865201B2 (en) | 2014-10-21 |
| NO20090095L (no) | 2009-01-07 |
| JP5205374B2 (ja) | 2013-06-05 |
| DK2032123T3 (da) | 2010-03-08 |
| BRPI0713298A2 (pt) | 2012-04-17 |
| HRP20100159T1 (hr) | 2010-05-31 |
| CY1109910T1 (el) | 2014-09-10 |
| MA30597B1 (fr) | 2009-07-01 |
| PL2032123T3 (pl) | 2010-06-30 |
| CN103071157A (zh) | 2013-05-01 |
| ATE455534T1 (de) | 2010-02-15 |
| EP2032123B1 (en) | 2010-01-20 |
| DE602007004486D1 (de) | 2010-03-11 |
| CO6140022A2 (es) | 2010-03-19 |
| EA018257B1 (ru) | 2013-06-28 |
| AR061771A1 (es) | 2008-09-17 |
| ES2339069T3 (es) | 2010-05-14 |
| EA200900087A1 (ru) | 2009-06-30 |
| HK1128587A1 (en) | 2009-10-30 |
| US20110091555A1 (en) | 2011-04-21 |
| EP2032123A1 (en) | 2009-03-11 |
| EP1872775A1 (en) | 2008-01-02 |
| WO2008000683A1 (en) | 2008-01-03 |
| JP2009541419A (ja) | 2009-11-26 |
| RS51279B (sr) | 2010-12-31 |
| PT2032123E (pt) | 2010-04-07 |
| KR20090033341A (ko) | 2009-04-02 |
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