HRP20100007T1 - Upotreba benzo-spojenih heterocikličkih derivata sulfamida za liječenje boli - Google Patents
Upotreba benzo-spojenih heterocikličkih derivata sulfamida za liječenje boli Download PDFInfo
- Publication number
- HRP20100007T1 HRP20100007T1 HR20100007T HRP20100007T HRP20100007T1 HR P20100007 T1 HRP20100007 T1 HR P20100007T1 HR 20100007 T HR20100007 T HR 20100007T HR P20100007 T HRP20100007 T HR P20100007T HR P20100007 T1 HRP20100007 T1 HR P20100007T1
- Authority
- HR
- Croatia
- Prior art keywords
- benzo
- dihydro
- image
- group
- pain
- Prior art date
Links
- 208000002193 Pain Diseases 0.000 title claims abstract 19
- -1 heterocycle sulfamide derivatives Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 claims abstract 15
- 150000001875 compounds Chemical class 0.000 claims abstract 13
- 229910052739 hydrogen Inorganic materials 0.000 claims abstract 12
- 239000001257 hydrogen Substances 0.000 claims abstract 12
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims abstract 11
- 150000003839 salts Chemical class 0.000 claims abstract 9
- 229910052736 halogen Inorganic materials 0.000 claims abstract 4
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims abstract 4
- 125000004432 carbon atom Chemical group C* 0.000 claims abstract 2
- 125000001183 hydrocarbyl group Chemical group 0.000 claims abstract 2
- 150000002367 halogens Chemical class 0.000 claims 3
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 3
- 208000004296 neuralgia Diseases 0.000 claims 3
- 208000021722 neuropathic pain Diseases 0.000 claims 3
- KXSAIQPPGSSNKX-ZETCQYMHSA-N (2s)-6-chloro-2-[(sulfamoylamino)methyl]-2,3-dihydro-1,4-benzodioxine Chemical compound ClC1=CC=C2O[C@@H](CNS(=O)(=O)N)COC2=C1 KXSAIQPPGSSNKX-ZETCQYMHSA-N 0.000 claims 2
- 208000000094 Chronic Pain Diseases 0.000 claims 2
- 206010065390 Inflammatory pain Diseases 0.000 claims 2
- 208000005298 acute pain Diseases 0.000 claims 2
- 208000032131 Diabetic Neuropathies Diseases 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
- C07D321/02—Seven-membered rings
- C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75168605P | 2005-12-19 | 2005-12-19 | |
| US77381206P | 2006-02-15 | 2006-02-15 | |
| US11/612,071 US8716231B2 (en) | 2005-12-19 | 2006-12-18 | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain |
| PCT/US2006/048539 WO2007075752A1 (en) | 2005-12-19 | 2006-12-19 | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20100007T1 true HRP20100007T1 (hr) | 2010-02-28 |
Family
ID=38007332
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20100007T HRP20100007T1 (hr) | 2005-12-19 | 2010-01-07 | Upotreba benzo-spojenih heterocikličkih derivata sulfamida za liječenje boli |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US8716231B2 (es) |
| EP (1) | EP1973540B1 (es) |
| JP (1) | JP5190377B2 (es) |
| KR (1) | KR20080077025A (es) |
| CN (1) | CN101378746B (es) |
| AT (1) | ATE447948T1 (es) |
| AU (1) | AU2006331734B2 (es) |
| BR (1) | BRPI0620018A2 (es) |
| CA (1) | CA2634115C (es) |
| CR (1) | CR10167A (es) |
| CY (1) | CY1109732T1 (es) |
| DE (1) | DE602006010442D1 (es) |
| DK (1) | DK1973540T3 (es) |
| EA (1) | EA016302B1 (es) |
| ES (1) | ES2335699T3 (es) |
| HK (1) | HK1125039A1 (es) |
| HR (1) | HRP20100007T1 (es) |
| IL (1) | IL192100A0 (es) |
| MY (1) | MY150903A (es) |
| NI (1) | NI200800169A (es) |
| NO (1) | NO20083005L (es) |
| NZ (1) | NZ569040A (es) |
| PL (1) | PL1973540T3 (es) |
| PT (1) | PT1973540E (es) |
| RS (1) | RS51249B (es) |
| SI (1) | SI1973540T1 (es) |
| WO (1) | WO2007075752A1 (es) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY147767A (en) | 2004-06-16 | 2013-01-31 | Janssen Pharmaceutica Nv | Novel sulfamate and sulfamide derivatives useful for the treatment of epilepsy and related disorders |
| AU2006249577A1 (en) * | 2005-05-20 | 2006-11-30 | Janssen Pharmaceutica N.V. | Process for preparation of sulfamide derivatives |
| US8497298B2 (en) | 2005-12-19 | 2013-07-30 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels |
| US8937096B2 (en) | 2005-12-19 | 2015-01-20 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder |
| US20070155827A1 (en) * | 2005-12-19 | 2007-07-05 | Smith-Swintosky Virginia L | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression |
| US8691867B2 (en) | 2005-12-19 | 2014-04-08 | Janssen Pharmaceutica Nv | Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction |
| TW200812573A (en) | 2006-05-19 | 2008-03-16 | Janssen Pharmaceutica Nv | Co-therapy for the treatment of epilepsy and related disorders |
| US20090247616A1 (en) * | 2008-03-26 | 2009-10-01 | Smith-Swintosky Virginia L | Use of benzo-fused heterocyle sulfamide derivatives for the treatment of anxiety |
| US20090247617A1 (en) * | 2008-03-26 | 2009-10-01 | Abdel-Magid Ahmed F | Process for the preparation of benzo-fused heteroaryl sulfamates |
| NZ588209A (en) * | 2008-04-29 | 2012-08-31 | Nsab Af Neurosearch Sweden Ab | 1-(2,3-dihydro-1,4-benzodioxin-2-yl)-methanamine derivatives for the modulation of dopaminergic function in the central nervous system |
| WO2009133110A1 (en) * | 2008-04-29 | 2009-11-05 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Modulators of dopamine neurotransmission |
| WO2009133109A1 (en) * | 2008-04-29 | 2009-11-05 | Nsab, Filial Af Neurosearch Sweden Ab, Sverige | Modulators of dopamine neurotransmission |
| BRPI0915890A2 (pt) | 2008-06-23 | 2015-11-03 | Janssen Pharmaceutica Nv | forma cristalina de (2s)-(-)-n-(6-cloro-2,3-di-hidro-benzo[1,4]dioxin-2-ilmetil)-sulfamida |
| US8815939B2 (en) * | 2008-07-22 | 2014-08-26 | Janssen Pharmaceutica Nv | Substituted sulfamide derivatives |
| AU2012316279A1 (en) | 2011-09-29 | 2014-04-17 | Janssen Pharmaceutica Nv | Process for the preparation of sulfamide derivatives |
| EP2760852A1 (en) | 2011-09-29 | 2014-08-06 | Janssen Pharmaceutica, N.V. | Improved process for the preparation of sulfamide derivatives |
| ES2673876T3 (es) | 2013-12-19 | 2018-06-26 | Eisai R&D Management Co., Ltd. | Agente terapéutico y/o preventivo que comprende un derivado de 1-indansulfamida para el dolor |
| MA53565A (fr) | 2018-09-04 | 2021-07-14 | Minerva Neurosciences Inc | Procédés d'utilisation d'un composé phénoxypropylamine pour le traitement de la douleur |
| RU2712918C1 (ru) * | 2019-08-01 | 2020-02-03 | Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации | Способ предотвращения острой боли при выполнении химического плевродеза после радикальных торакопластических операций онкологического характера |
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-
2006
- 2006-12-18 US US11/612,071 patent/US8716231B2/en not_active Expired - Fee Related
- 2006-12-19 AU AU2006331734A patent/AU2006331734B2/en not_active Ceased
- 2006-12-19 CA CA2634115A patent/CA2634115C/en not_active Expired - Fee Related
- 2006-12-19 MY MYPI20082183 patent/MY150903A/en unknown
- 2006-12-19 ES ES06847800T patent/ES2335699T3/es active Active
- 2006-12-19 PL PL06847800T patent/PL1973540T3/pl unknown
- 2006-12-19 EP EP06847800A patent/EP1973540B1/en active Active
- 2006-12-19 CN CN2006800530302A patent/CN101378746B/zh not_active Expired - Fee Related
- 2006-12-19 BR BRPI0620018-4A patent/BRPI0620018A2/pt not_active IP Right Cessation
- 2006-12-19 RS RSP-2010/0047A patent/RS51249B/sr unknown
- 2006-12-19 DE DE602006010442T patent/DE602006010442D1/de active Active
- 2006-12-19 WO PCT/US2006/048539 patent/WO2007075752A1/en active Application Filing
- 2006-12-19 DK DK06847800.7T patent/DK1973540T3/da active
- 2006-12-19 JP JP2008547472A patent/JP5190377B2/ja not_active Expired - Fee Related
- 2006-12-19 PT PT06847800T patent/PT1973540E/pt unknown
- 2006-12-19 SI SI200630556T patent/SI1973540T1/sl unknown
- 2006-12-19 EA EA200870091A patent/EA016302B1/ru not_active IP Right Cessation
- 2006-12-19 KR KR1020087017495A patent/KR20080077025A/ko active IP Right Grant
- 2006-12-19 NZ NZ569040A patent/NZ569040A/en not_active IP Right Cessation
- 2006-12-19 AT AT06847800T patent/ATE447948T1/de active
-
2008
- 2008-06-12 IL IL192100A patent/IL192100A0/en unknown
- 2008-06-18 NI NI200800169A patent/NI200800169A/es unknown
- 2008-07-03 NO NO20083005A patent/NO20083005L/no not_active Application Discontinuation
- 2008-07-21 CR CR10167A patent/CR10167A/es not_active Application Discontinuation
-
2009
- 2009-03-24 HK HK09102820.3A patent/HK1125039A1/xx not_active IP Right Cessation
-
2010
- 2010-01-07 HR HR20100007T patent/HRP20100007T1/hr unknown
- 2010-01-15 CY CY20101100044T patent/CY1109732T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006331734B2 (en) | 2012-12-20 |
| EP1973540B1 (en) | 2009-11-11 |
| HK1125039A1 (en) | 2009-07-31 |
| CA2634115A1 (en) | 2007-07-05 |
| US8716231B2 (en) | 2014-05-06 |
| US20070155822A1 (en) | 2007-07-05 |
| BRPI0620018A2 (pt) | 2011-10-25 |
| EA200870091A1 (ru) | 2009-12-30 |
| ATE447948T1 (de) | 2009-11-15 |
| AU2006331734A1 (en) | 2007-07-05 |
| PL1973540T3 (pl) | 2010-04-30 |
| KR20080077025A (ko) | 2008-08-20 |
| RS51249B (sr) | 2010-12-31 |
| DK1973540T3 (da) | 2010-02-01 |
| DE602006010442D1 (de) | 2009-12-24 |
| NI200800169A (es) | 2012-05-28 |
| CA2634115C (en) | 2014-11-18 |
| MY150903A (en) | 2014-03-14 |
| CN101378746B (zh) | 2013-07-17 |
| WO2007075752A1 (en) | 2007-07-05 |
| NZ569040A (en) | 2011-04-29 |
| PT1973540E (pt) | 2010-01-28 |
| CR10167A (es) | 2009-01-16 |
| EP1973540A1 (en) | 2008-10-01 |
| SI1973540T1 (sl) | 2010-03-31 |
| EA016302B1 (ru) | 2012-04-30 |
| CY1109732T1 (el) | 2014-09-10 |
| JP5190377B2 (ja) | 2013-04-24 |
| IL192100A0 (en) | 2009-08-03 |
| ES2335699T3 (es) | 2010-03-31 |
| CN101378746A (zh) | 2009-03-04 |
| NO20083005L (no) | 2008-09-16 |
| JP2009520035A (ja) | 2009-05-21 |
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