HRP20050354B1 - - Google Patents

Info

Publication number
HRP20050354B1
HRP20050354B1 HR20050354A HRP20050354A HRP20050354B1 HR P20050354 B1 HRP20050354 B1 HR P20050354B1 HR 20050354 A HR20050354 A HR 20050354A HR P20050354 A HRP20050354 A HR P20050354A HR P20050354 B1 HRP20050354 B1 HR P20050354B1
Authority
HR
Croatia
Prior art keywords
photoprotein
protein
region
replacing
cells
Prior art date
Application number
HR20050354A
Other languages
English (en)
Croatian (hr)
Inventor
Foti Maria
Lohmer Stefan
Original Assignee
Axxam S.R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axxam S.R.L. filed Critical Axxam S.R.L.
Publication of HRP20050354A2 publication Critical patent/HRP20050354A2/xx
Publication of HRP20050354B1 publication Critical patent/HRP20050354B1/xx

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Dental Preparations (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
HR20050354A 2002-10-21 2003-10-21 Photoprotein with improved bioluminescence HRP20050354A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02023452A EP1413584B1 (en) 2002-10-21 2002-10-21 Photoprotein with improved bioluminescence
PCT/EP2003/011626 WO2004035620A1 (en) 2002-10-21 2003-10-21 Photoprotein with improved bioluminescence

Publications (2)

Publication Number Publication Date
HRP20050354A2 HRP20050354A2 (en) 2005-08-31
HRP20050354B1 true HRP20050354B1 (enExample) 2007-01-31

Family

ID=32049982

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20050354A HRP20050354A2 (en) 2002-10-21 2003-10-21 Photoprotein with improved bioluminescence

Country Status (21)

Country Link
US (1) US7601805B2 (enExample)
EP (1) EP1413584B1 (enExample)
JP (1) JP4459058B2 (enExample)
KR (1) KR20050053783A (enExample)
CN (1) CN1317299C (enExample)
AT (1) ATE290016T1 (enExample)
AU (1) AU2003287962B2 (enExample)
BR (1) BR0306589A (enExample)
CA (1) CA2503145A1 (enExample)
DE (1) DE60203123T2 (enExample)
DK (1) DK1413584T3 (enExample)
ES (1) ES2237643T3 (enExample)
HR (1) HRP20050354A2 (enExample)
IL (1) IL168158A (enExample)
MX (1) MXPA05004148A (enExample)
NO (1) NO20051921L (enExample)
PL (1) PL376323A1 (enExample)
RS (1) RS54004A (enExample)
RU (1) RU2340629C2 (enExample)
WO (1) WO2004035620A1 (enExample)
ZA (1) ZA200503197B (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10342670A1 (de) * 2003-09-16 2005-04-21 Bayer Healthcare Ag Isoliertes Photoprotein mtClytin, sowie dessen Verwendung
EP1700865A1 (en) * 2005-03-11 2006-09-13 AXXAM S.r.l. Photoproteins with enhanced bioluminescence and their use as intracellular calcium indicators
EP1973937B1 (en) * 2006-01-11 2011-05-25 Axxam S.P.A. Luminescent transgenic non human animals, progeny, cell derivatives and uses thereof
EP1808441A1 (en) * 2006-01-11 2007-07-18 AXXAM S.p.A. Luminescent stem cells, transgenic mammals and uses thereof
EP2489745B1 (en) 2006-06-05 2017-01-11 California Institute Of Technology Real time micro arrays
US11001881B2 (en) 2006-08-24 2021-05-11 California Institute Of Technology Methods for detecting analytes
US8637436B2 (en) 2006-08-24 2014-01-28 California Institute Of Technology Integrated semiconductor bioarray
JP5374840B2 (ja) 2006-07-20 2013-12-25 Jnc株式会社 カルシウム結合発光蛋白質、それをコードする遺伝子およびその用途
US8048626B2 (en) 2006-07-28 2011-11-01 California Institute Of Technology Multiplex Q-PCR arrays
US11525156B2 (en) 2006-07-28 2022-12-13 California Institute Of Technology Multiplex Q-PCR arrays
US11560588B2 (en) 2006-08-24 2023-01-24 California Institute Of Technology Multiplex Q-PCR arrays
GB0625678D0 (en) * 2006-12-21 2007-01-31 Lux Biotechnology Ltd Composition and method for detection of demineralisation
US8431698B2 (en) * 2007-08-29 2013-04-30 Biolume Inc. Bioluminescent endoscopy methods and compounds
JP5304275B2 (ja) * 2009-01-29 2013-10-02 Jnc株式会社 アポクライティン−iiをコードするコドン最適化核酸およびその使用方法
KR101834574B1 (ko) * 2009-01-29 2018-03-05 커먼웰쓰 사이언티픽 앤드 인더스트리얼 리서치 오가니제이션 G 단백질 커플링 수용체 활성화 측정
AU2011323418B2 (en) * 2010-11-02 2017-07-27 Promega Corporation Novel coelenterazine substrates and methods of use
EP2635583B1 (en) * 2010-11-02 2015-06-03 Promega Corporation Coelenterazine derivatives and methods of using same
CN103261415B (zh) * 2010-12-24 2016-08-10 大塚制药株式会社 检测生理活性物质的生物测定法
AU2013204332B2 (en) 2012-04-16 2015-07-16 Commonwealth Scientific And Industrial Research Organisation Methods and systems for detecting an analyte or classifying a sample
US9927430B2 (en) 2014-01-29 2018-03-27 Promega Corporation Pro-substrates for live cell applications
JP6703484B2 (ja) 2014-01-29 2020-06-03 プロメガ コーポレイションPromega Corporation 細胞による取り込み測定のための、標識用試薬としての、キノンでマスクされたプローブ
US9708647B2 (en) 2015-03-23 2017-07-18 Insilixa, Inc. Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays
US9499861B1 (en) 2015-09-10 2016-11-22 Insilixa, Inc. Methods and systems for multiplex quantitative nucleic acid amplification
WO2017155858A1 (en) 2016-03-07 2017-09-14 Insilixa, Inc. Nucleic acid sequence identification using solid-phase cyclic single base extension
PL3538665T3 (pl) 2016-11-14 2024-05-06 PPB Technology Pty Ltd Cząsteczki czujnika proteazy
GB201700317D0 (en) 2017-01-09 2017-02-22 Calcivis Ltd Detection device
SG11202001121WA (en) 2017-08-08 2020-03-30 Commw Scient Ind Res Org Carbohydrate sensors
US11013411B1 (en) 2018-06-13 2021-05-25 The Research Foundation For The State University Of New York Chromatic bioluminescence as a cellular level readout system of neural activity
CN119510370A (zh) 2019-03-14 2025-02-25 因斯利克萨公司 基于时间门控的荧光检测的方法和系统
USD1042180S1 (en) 2020-05-28 2024-09-17 Calcivis Limited Dental detection device
RU2770490C1 (ru) * 2021-07-14 2022-04-18 Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр "Красноярский научный центр Сибирского отделения Российской академии наук" Рекомбинантная плазмидная ДНК pET19b-Surv-OL, обеспечивающая синтез гибридного белка сурвивин-обелин (Surv-OL) и гибридный белок, связываемый анти-сурвивин антителами и обладающий биолюминесцентной активностью

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2114175C1 (ru) * 1993-09-14 1998-06-27 Институт белка РАН Способ клонирования нуклеиновых кислот

Also Published As

Publication number Publication date
US7601805B2 (en) 2009-10-13
BR0306589A (pt) 2004-11-30
US20070065818A1 (en) 2007-03-22
KR20050053783A (ko) 2005-06-08
AU2003287962B2 (en) 2010-06-17
WO2004035620A1 (en) 2004-04-29
CA2503145A1 (en) 2004-04-29
RS54004A (sr) 2006-10-27
EP1413584B1 (en) 2005-03-02
RU2340629C2 (ru) 2008-12-10
ZA200503197B (en) 2006-06-28
DE60203123D1 (de) 2005-04-07
DE60203123T2 (de) 2005-07-21
ES2237643T3 (es) 2005-08-01
CN1705680A (zh) 2005-12-07
CN1317299C (zh) 2007-05-23
ATE290016T1 (de) 2005-03-15
JP2006517784A (ja) 2006-08-03
DK1413584T3 (da) 2005-07-04
IL168158A (en) 2010-06-16
JP4459058B2 (ja) 2010-04-28
HRP20050354A2 (en) 2005-08-31
NO20051921L (no) 2005-05-23
AU2003287962A1 (en) 2004-05-04
RU2005111772A (ru) 2005-09-10
PL376323A1 (en) 2005-12-27
EP1413584A1 (en) 2004-04-28
MXPA05004148A (es) 2005-08-03

Similar Documents

Publication Publication Date Title
HRP20050354B1 (enExample)
ATE393169T1 (de) Il-7-fusionsproteine mit antikörperportionen, deren herstellung und deren verwendung
NO20052309D0 (no) Nutrasoytisk mangostanblanding.
GEP20105118B (en) Anti-vegf antibodies
ATE445386T1 (de) Polymerische parfümpartikel
DE60138927D1 (de) Menschlicher rezeptor für tumor necrosis factor
ATE473011T1 (de) Modifizierte transferrin-fusionsproteine mit doppelten transferrin-amino- oder carboxy- terminalen domänen
DK1553975T3 (da) Optimerede Fc-varianter og fremgangsmåder til generering heraf.
CR9599A (es) Proteinas de union a il-12/p40
ATE485359T1 (de) Verwendung von grenzflächenaktiven, nicht- enzymatischen proteinen für die textilwäsche
EA200300464A1 (ru) ГУМАНИЗИРОВАННОЕ АНТИТЕЛО ПРОТИВ РЕЦЕПТОРА ЛИМФОТОКСИНА-β (ВАРИАНТЫ), КОМПОЗИЦИЯ, СПОСОБ ЛЕЧЕНИЯ ИЛИ СНИЖЕНИЯ РИСКА РАЗВИТИЯ, ТЯЖЕСТИ ИЛИ ПОСЛЕДСТВИЙ НЕОПЛАЗИИ У ЧЕЛОВЕКА, ВЫДЕЛЕННАЯ НУКЛЕИНОВАЯ КИСЛОТА (ВАРИАНТЫ), КЛЕТКА КЛЕТОЧНОЙ ЛИНИИ
ATE272114T1 (de) Rezeptoren für il-18
WO2006071377A3 (en) Auxiliary eyewear assembly with micromagnetic attachment
DE60217702D1 (de) Behälter mit wiederverschliessbarer, durch einen klebstoff am behälter geklebter abdeckung
SG158141A1 (en) Pancreatic polypeptide family motifs, polypeptides and methods comprising the same
DOP2001000219A (es) Applicator
DK1645626T3 (da) Cellelinie
DE602006018856D1 (de) Neue nutrazeutika-zusammensetzungen
EA200401621A1 (ru) Модуляторы сск-1 рецепторов
BR0015872A (pt) Agentes antitrombóticos
ATE382778T1 (de) Pumpenkombination
ATE452646T1 (de) Zusammensetzungen mit epigallocatechingallat und proteinhydrolysat
EA200500878A1 (ru) Кальцилитические соединения
ATE550345T1 (de) Sfrp, mit sfrp-interagierende peptidmotive sowie verwendungsverfahren
GB0205910D0 (en) Arrays and methods

Legal Events

Date Code Title Description
A1OB Publication of a patent application
ARAI Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
B1PR Patent granted
ODRP Renewal fee for the maintenance of a patent

Payment date: 20091015

Year of fee payment: 7

PBON Lapse due to non-payment of renewal fee

Effective date: 20101022