DK1413584T3 - Fotoprotein med forbedret bioluminescens - Google Patents

Fotoprotein med forbedret bioluminescens

Info

Publication number
DK1413584T3
DK1413584T3 DK02023452T DK02023452T DK1413584T3 DK 1413584 T3 DK1413584 T3 DK 1413584T3 DK 02023452 T DK02023452 T DK 02023452T DK 02023452 T DK02023452 T DK 02023452T DK 1413584 T3 DK1413584 T3 DK 1413584T3
Authority
DK
Denmark
Prior art keywords
photoprotein
iii
chosen
sequence
region
Prior art date
Application number
DK02023452T
Other languages
Danish (da)
English (en)
Inventor
Maria Foti
Stefan Lohmer
Original Assignee
Axxam S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axxam S R L filed Critical Axxam S R L
Application granted granted Critical
Publication of DK1413584T3 publication Critical patent/DK1413584T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Dental Preparations (AREA)
DK02023452T 2002-10-21 2002-10-21 Fotoprotein med forbedret bioluminescens DK1413584T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02023452A EP1413584B1 (en) 2002-10-21 2002-10-21 Photoprotein with improved bioluminescence

Publications (1)

Publication Number Publication Date
DK1413584T3 true DK1413584T3 (da) 2005-07-04

Family

ID=32049982

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02023452T DK1413584T3 (da) 2002-10-21 2002-10-21 Fotoprotein med forbedret bioluminescens

Country Status (21)

Country Link
US (1) US7601805B2 (enExample)
EP (1) EP1413584B1 (enExample)
JP (1) JP4459058B2 (enExample)
KR (1) KR20050053783A (enExample)
CN (1) CN1317299C (enExample)
AT (1) ATE290016T1 (enExample)
AU (1) AU2003287962B2 (enExample)
BR (1) BR0306589A (enExample)
CA (1) CA2503145A1 (enExample)
DE (1) DE60203123T2 (enExample)
DK (1) DK1413584T3 (enExample)
ES (1) ES2237643T3 (enExample)
HR (1) HRP20050354A2 (enExample)
IL (1) IL168158A (enExample)
MX (1) MXPA05004148A (enExample)
NO (1) NO20051921L (enExample)
PL (1) PL376323A1 (enExample)
RS (1) RS54004A (enExample)
RU (1) RU2340629C2 (enExample)
WO (1) WO2004035620A1 (enExample)
ZA (1) ZA200503197B (enExample)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10342670A1 (de) * 2003-09-16 2005-04-21 Bayer Healthcare Ag Isoliertes Photoprotein mtClytin, sowie dessen Verwendung
EP1700865A1 (en) * 2005-03-11 2006-09-13 AXXAM S.r.l. Photoproteins with enhanced bioluminescence and their use as intracellular calcium indicators
EP1808441A1 (en) * 2006-01-11 2007-07-18 AXXAM S.p.A. Luminescent stem cells, transgenic mammals and uses thereof
EP1973938B1 (en) * 2006-01-11 2011-04-06 Axxam S.P.A. Luminescent stem cells and uses thereof
US11001881B2 (en) 2006-08-24 2021-05-11 California Institute Of Technology Methods for detecting analytes
US8637436B2 (en) 2006-08-24 2014-01-28 California Institute Of Technology Integrated semiconductor bioarray
EP2489745B1 (en) 2006-06-05 2017-01-11 California Institute Of Technology Real time micro arrays
JP5374840B2 (ja) 2006-07-20 2013-12-25 Jnc株式会社 カルシウム結合発光蛋白質、それをコードする遺伝子およびその用途
WO2008014485A2 (en) 2006-07-28 2008-01-31 California Institute Of Technology Multiplex q-pcr arrays
US11525156B2 (en) 2006-07-28 2022-12-13 California Institute Of Technology Multiplex Q-PCR arrays
US11560588B2 (en) 2006-08-24 2023-01-24 California Institute Of Technology Multiplex Q-PCR arrays
GB0625678D0 (en) * 2006-12-21 2007-01-31 Lux Biotechnology Ltd Composition and method for detection of demineralisation
US8431698B2 (en) * 2007-08-29 2013-04-30 Biolume Inc. Bioluminescent endoscopy methods and compounds
EP2382470B1 (en) * 2009-01-29 2014-12-10 Commonwealth Scientific and Industrial Research Organisation Measuring g protein coupled receptor activation
JP5304275B2 (ja) * 2009-01-29 2013-10-02 Jnc株式会社 アポクライティン−iiをコードするコドン最適化核酸およびその使用方法
BR112013010855A2 (pt) 2010-11-02 2017-06-27 Promega Corp luciferases derivadas de oplophorus, novos substratos de coelenterazina e métodos de uso
SG189494A1 (en) * 2010-11-02 2013-05-31 Promega Corp Coelenterazine derivatives and methods of using same
EP2657336B1 (en) 2010-12-24 2018-07-04 Otsuka Pharmaceutical Co., Ltd. Bioassay method for detecting physiologically active substance
AU2013204332B2 (en) * 2012-04-16 2015-07-16 Commonwealth Scientific And Industrial Research Organisation Methods and systems for detecting an analyte or classifying a sample
EP3099683B1 (en) 2014-01-29 2020-08-05 Promega Corporation Quinone-masked probes as labeling reagents for cell uptake measurements
EP3099691B1 (en) 2014-01-29 2019-11-20 Promega Corporation Pro-substrates for live cell applications
US9708647B2 (en) 2015-03-23 2017-07-18 Insilixa, Inc. Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays
US9499861B1 (en) 2015-09-10 2016-11-22 Insilixa, Inc. Methods and systems for multiplex quantitative nucleic acid amplification
WO2017155858A1 (en) 2016-03-07 2017-09-14 Insilixa, Inc. Nucleic acid sequence identification using solid-phase cyclic single base extension
JP2020510406A (ja) 2016-11-14 2020-04-09 コモンウェルス サイエンティフィック アンド インダストリアル リサーチ オーガナイゼーション プロテアーゼセンサー分子
GB201700317D0 (en) 2017-01-09 2017-02-22 Calcivis Ltd Detection device
PL3665481T3 (pl) 2017-08-08 2024-02-05 PPB Technology Pty Ltd Czujniki węglowodanów
WO2019241318A1 (en) * 2018-06-13 2019-12-19 Cornell University Bioluminescent markers of neural activity
JP7687957B2 (ja) 2019-03-14 2025-06-03 インシリクサ, インコーポレイテッド 時間ゲート蛍光ベースの検出のための方法およびシステム
USD1042180S1 (en) 2020-05-28 2024-09-17 Calcivis Limited Dental detection device
RU2770490C1 (ru) * 2021-07-14 2022-04-18 Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр "Красноярский научный центр Сибирского отделения Российской академии наук" Рекомбинантная плазмидная ДНК pET19b-Surv-OL, обеспечивающая синтез гибридного белка сурвивин-обелин (Surv-OL) и гибридный белок, связываемый анти-сурвивин антителами и обладающий биолюминесцентной активностью

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2114175C1 (ru) * 1993-09-14 1998-06-27 Институт белка РАН Способ клонирования нуклеиновых кислот

Also Published As

Publication number Publication date
RU2005111772A (ru) 2005-09-10
NO20051921L (no) 2005-05-23
AU2003287962B2 (en) 2010-06-17
AU2003287962A1 (en) 2004-05-04
PL376323A1 (en) 2005-12-27
HRP20050354B1 (enExample) 2007-01-31
ZA200503197B (en) 2006-06-28
JP4459058B2 (ja) 2010-04-28
EP1413584B1 (en) 2005-03-02
DE60203123D1 (de) 2005-04-07
CA2503145A1 (en) 2004-04-29
RU2340629C2 (ru) 2008-12-10
ES2237643T3 (es) 2005-08-01
IL168158A (en) 2010-06-16
MXPA05004148A (es) 2005-08-03
RS54004A (sr) 2006-10-27
KR20050053783A (ko) 2005-06-08
BR0306589A (pt) 2004-11-30
ATE290016T1 (de) 2005-03-15
WO2004035620A1 (en) 2004-04-29
CN1317299C (zh) 2007-05-23
HRP20050354A2 (en) 2005-08-31
EP1413584A1 (en) 2004-04-28
CN1705680A (zh) 2005-12-07
US7601805B2 (en) 2009-10-13
US20070065818A1 (en) 2007-03-22
DE60203123T2 (de) 2005-07-21
JP2006517784A (ja) 2006-08-03

Similar Documents

Publication Publication Date Title
DK1413584T3 (da) Fotoprotein med forbedret bioluminescens
DE69833784D1 (de) Polypeptide mit aminopeptidaseaktivität und für diese kodierende nukleinsäuren
DE69841102D1 (de) Monoklonaler antikörper gegen ein prion protein und dessen verwendung zum nachweis von prionen
DE60033138D1 (de) Polypeptide mit galaktoseoxidaseaktivität und dafür kodierende nukleisäuren
CY1109725T1 (el) Ειδικες δεσμευομενες πρωτεϊνες και χρησεις αυτων
DE69131580D1 (de) GDF-1 und UOG1 Proteine
ATE414775T1 (de) Polypeptide mit prolyldipeptidylaminopeptidase- aktivität und dafür kodierende nukleinsäuren
DE69930955D1 (de) Polypeptide mit lysophospholipaseaktivität und nukleinesäuren die sie kodieren
ATE450603T1 (de) Polypeptide mit verzweigungsenzym-aktivität und für diese kodierende nukleinsäuren
ATE135371T1 (de) Mit akuter pankreatitis assoziiertes protein, mittel zur diagnose von akuter pankreatitis
WO2002018443A3 (en) A recombinant monoclonal antibody to phosphotyrosine-containing proteins
ATE424457T1 (de) Menschliche stra6 polypeptide
DE69837475D1 (de) Polypeptide mit aminopeptidaseaktivität und dafür kodierende nukleinsäuren
AU1959001A (en) Histone deacetylase-8 proteins, nucleic acids, and methods of use
WO2002046409A3 (en) Proteins and nucleic acids encoding same
DE602004032144D1 (de) Für fructooligosaccharid-nutzende verbindungen codierende nukleinsäuren aus lactobacillus acidophilus und verwendungen davon
AU2001238064A1 (en) 18477, a human protein kinase and uses therefor
WO2001064913A3 (en) Cell cycle proteins associated with rad9, compositions and methods of use
DE69828902D1 (de) Polypeptide mit 5-aminolevulinsäure synthaseaktivität und deren nukleinsäuren
DE60026049D1 (de) POLYPEPTIDE MIT GLUCANOTRANSFERASE AKTIVITÄT UND DAFüR KODIERENDE NUKLEINSÄUREN
WO2000043419A3 (en) Exocytosis pathway proteins and methods of use
WO2001036476A3 (en) Ing2, an iaps associated cell cycle protein, compositions and methods of use
WO2003076569A3 (en) Novel polypeptides having sequence similarity to gdnfr and nucleic acids encoding the same
WO2000055192A3 (de) Hämocyanin und dafür kodierende nukleinsäuresequenz
WO1999042586A3 (en) Exo1 and exo2, exocytotic proteins