RU2340629C2 - Фотобелок с повышенной биолюминесценцией - Google Patents

Фотобелок с повышенной биолюминесценцией Download PDF

Info

Publication number
RU2340629C2
RU2340629C2 RU2005111772/13A RU2005111772A RU2340629C2 RU 2340629 C2 RU2340629 C2 RU 2340629C2 RU 2005111772/13 A RU2005111772/13 A RU 2005111772/13A RU 2005111772 A RU2005111772 A RU 2005111772A RU 2340629 C2 RU2340629 C2 RU 2340629C2
Authority
RU
Russia
Prior art keywords
protein
chimeric
acid sequence
amino acid
obelin
Prior art date
Application number
RU2005111772/13A
Other languages
English (en)
Russian (ru)
Other versions
RU2005111772A (ru
Inventor
Мари ФОТИ (IT)
Мария ФОТИ
Штефан ЛОМЕР (IT)
Штефан ЛОМЕР
Original Assignee
Аксам С.Р.Л.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Аксам С.Р.Л. filed Critical Аксам С.Р.Л.
Publication of RU2005111772A publication Critical patent/RU2005111772A/ru
Application granted granted Critical
Publication of RU2340629C2 publication Critical patent/RU2340629C2/ru

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Dental Preparations (AREA)
RU2005111772/13A 2002-10-21 2003-10-21 Фотобелок с повышенной биолюминесценцией RU2340629C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02023452.2 2002-10-21
EP02023452A EP1413584B1 (en) 2002-10-21 2002-10-21 Photoprotein with improved bioluminescence

Publications (2)

Publication Number Publication Date
RU2005111772A RU2005111772A (ru) 2005-09-10
RU2340629C2 true RU2340629C2 (ru) 2008-12-10

Family

ID=32049982

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2005111772/13A RU2340629C2 (ru) 2002-10-21 2003-10-21 Фотобелок с повышенной биолюминесценцией

Country Status (21)

Country Link
US (1) US7601805B2 (enExample)
EP (1) EP1413584B1 (enExample)
JP (1) JP4459058B2 (enExample)
KR (1) KR20050053783A (enExample)
CN (1) CN1317299C (enExample)
AT (1) ATE290016T1 (enExample)
AU (1) AU2003287962B2 (enExample)
BR (1) BR0306589A (enExample)
CA (1) CA2503145A1 (enExample)
DE (1) DE60203123T2 (enExample)
DK (1) DK1413584T3 (enExample)
ES (1) ES2237643T3 (enExample)
HR (1) HRP20050354A2 (enExample)
IL (1) IL168158A (enExample)
MX (1) MXPA05004148A (enExample)
NO (1) NO20051921L (enExample)
PL (1) PL376323A1 (enExample)
RS (1) RS54004A (enExample)
RU (1) RU2340629C2 (enExample)
WO (1) WO2004035620A1 (enExample)
ZA (1) ZA200503197B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2407750C2 (ru) * 2005-03-11 2010-12-27 Аксам Спа Фотобелки с усиленной биолюминесценцией и их использование в качестве внутриклеточных индикаторов кальция
RU2770490C1 (ru) * 2021-07-14 2022-04-18 Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр "Красноярский научный центр Сибирского отделения Российской академии наук" Рекомбинантная плазмидная ДНК pET19b-Surv-OL, обеспечивающая синтез гибридного белка сурвивин-обелин (Surv-OL) и гибридный белок, связываемый анти-сурвивин антителами и обладающий биолюминесцентной активностью

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10342670A1 (de) * 2003-09-16 2005-04-21 Bayer Healthcare Ag Isoliertes Photoprotein mtClytin, sowie dessen Verwendung
EP1808441A1 (en) * 2006-01-11 2007-07-18 AXXAM S.p.A. Luminescent stem cells, transgenic mammals and uses thereof
KR20080100420A (ko) * 2006-01-11 2008-11-18 악삼 에스피에이 발광성 줄기 세포들 및 이들의 용도
US11001881B2 (en) 2006-08-24 2021-05-11 California Institute Of Technology Methods for detecting analytes
WO2007143669A2 (en) 2006-06-05 2007-12-13 California Institute Of Technology Real time micro arrays
US8637436B2 (en) 2006-08-24 2014-01-28 California Institute Of Technology Integrated semiconductor bioarray
JP5374840B2 (ja) 2006-07-20 2013-12-25 Ｊｎｃ株式会社 カルシウム結合発光蛋白質、それをコードする遺伝子およびその用途
US11525156B2 (en) 2006-07-28 2022-12-13 California Institute Of Technology Multiplex Q-PCR arrays
WO2008014485A2 (en) 2006-07-28 2008-01-31 California Institute Of Technology Multiplex q-pcr arrays
US11560588B2 (en) 2006-08-24 2023-01-24 California Institute Of Technology Multiplex Q-PCR arrays
GB0625678D0 (en) * 2006-12-21 2007-01-31 Lux Biotechnology Ltd Composition and method for detection of demineralisation
WO2009032218A1 (en) * 2007-08-29 2009-03-12 Biolume Inc. Bioluminescent endoscopy methods and compounds
CA2748500C (en) * 2009-01-29 2017-10-17 Commonwealth Scientific And Industrial Research Organisation Measuring g protein coupled receptor activation
JP5304275B2 (ja) * 2009-01-29 2013-10-02 Ｊｎｃ株式会社 アポクライティン−ｉｉをコードするコドン最適化核酸およびその使用方法
DK2635583T3 (en) * 2010-11-02 2015-08-03 Promega Corp Coelenterazinderivater and methods of use thereof
SG10202103336SA (en) 2010-11-02 2021-04-29 Promega Corp Novel coelenterazine substrates and methods of use
BR112013015605A2 (pt) * 2010-12-24 2016-10-11 Otsuka Pharma Co Ltd método de bioanálise para detecção de substância fisiologicamente ativa
AU2013204332B2 (en) 2012-04-16 2015-07-16 Commonwealth Scientific And Industrial Research Organisation Methods and systems for detecting an analyte or classifying a sample
JP6588917B2 (ja) 2014-01-29 2019-10-09 プロメガ コーポレイションＰｒｏｍｅｇａ Ｃｏｒｐｏｒａｔｉｏｎ 生細胞への適用のためのプロ基質
WO2015116867A1 (en) 2014-01-29 2015-08-06 Promega Corporation Quinone-masked probes as labeling reagents for cell uptake measurements
US9708647B2 (en) 2015-03-23 2017-07-18 Insilixa, Inc. Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays
US9499861B1 (en) 2015-09-10 2016-11-22 Insilixa, Inc. Methods and systems for multiplex quantitative nucleic acid amplification
WO2017155858A1 (en) 2016-03-07 2017-09-14 Insilixa, Inc. Nucleic acid sequence identification using solid-phase cyclic single base extension
EP3538665B1 (en) 2016-11-14 2024-01-03 PPB Technology Pty Ltd Protease sensor molecules
GB201700317D0 (en) 2017-01-09 2017-02-22 Calcivis Ltd Detection device
PL3665481T3 (pl) 2017-08-08 2024-02-05 PPB Technology Pty Ltd Czujniki węglowodanów
WO2019241318A1 (en) * 2018-06-13 2019-12-19 Cornell University Bioluminescent markers of neural activity
EP3937780A4 (en) 2019-03-14 2022-12-07 InSilixa, Inc. METHODS AND SYSTEMS FOR TIMED FLUORESCENCE-BASED DETECTION
USD1042180S1 (en) 2020-05-28 2024-09-17 Calcivis Limited Dental detection device

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2114175C1 (ru) * 1993-09-14 1998-06-27 Институт белка РАН Способ клонирования нуклеиновых кислот

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2114175C1 (ru) * 1993-09-14 1998-06-27 Институт белка РАН Способ клонирования нуклеиновых кислот

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ILLARIONOV В. ЕТ AL, Gene, 1995, 153(2), 273-274. MARKOVA S. ЕТ AL., Biochemistry, 2002, 41(7), 2227-2236 INOUYE S. and TSUJI F., FEBS Lett., 1993, 315(3), 343-346. *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2407750C2 (ru) * 2005-03-11 2010-12-27 Аксам Спа Фотобелки с усиленной биолюминесценцией и их использование в качестве внутриклеточных индикаторов кальция
RU2770490C1 (ru) * 2021-07-14 2022-04-18 Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр "Красноярский научный центр Сибирского отделения Российской академии наук" Рекомбинантная плазмидная ДНК pET19b-Surv-OL, обеспечивающая синтез гибридного белка сурвивин-обелин (Surv-OL) и гибридный белок, связываемый анти-сурвивин антителами и обладающий биолюминесцентной активностью

Also Published As

Publication number Publication date
EP1413584A1 (en) 2004-04-28
CN1705680A (zh) 2005-12-07
ATE290016T1 (de) 2005-03-15
DE60203123D1 (de) 2005-04-07
HRP20050354A2 (en) 2005-08-31
JP2006517784A (ja) 2006-08-03
HRP20050354B1 (enExample) 2007-01-31
MXPA05004148A (es) 2005-08-03
NO20051921L (no) 2005-05-23
RS54004A (sr) 2006-10-27
US7601805B2 (en) 2009-10-13
RU2005111772A (ru) 2005-09-10
DE60203123T2 (de) 2005-07-21
WO2004035620A1 (en) 2004-04-29
AU2003287962A1 (en) 2004-05-04
CA2503145A1 (en) 2004-04-29
ES2237643T3 (es) 2005-08-01
BR0306589A (pt) 2004-11-30
ZA200503197B (en) 2006-06-28
KR20050053783A (ko) 2005-06-08
JP4459058B2 (ja) 2010-04-28
CN1317299C (zh) 2007-05-23
DK1413584T3 (da) 2005-07-04
AU2003287962B2 (en) 2010-06-17
EP1413584B1 (en) 2005-03-02
PL376323A1 (en) 2005-12-27
US20070065818A1 (en) 2007-03-22
IL168158A (en) 2010-06-16

Similar Documents

Publication Publication Date Title
RU2340629C2 (ru) Фотобелок с повышенной биолюминесценцией
IL185857A (en) Clytin proteins with enhanced bioluminescence and their use as intracellular calcium indicators
JP4480674B2 (ja) コペポーダ種由来の蛍光たんぱく質および該たんぱく質の使用方法
EP1997885A1 (en) Fluorescent proteins and methods of use thereof
EP1339853A1 (de) Isolierte luziferasen sowie deren verwendung
EP1908775A1 (en) Fluorescent proteins from the Ctenophora phylum and methods of use thereof

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20101022