BR0306589A - Fotoproteìna com aperfeiçoada bioluminescência - Google Patents

Fotoproteìna com aperfeiçoada bioluminescência

Info

Publication number
BR0306589A
BR0306589A BR0306589-8A BR0306589A BR0306589A BR 0306589 A BR0306589 A BR 0306589A BR 0306589 A BR0306589 A BR 0306589A BR 0306589 A BR0306589 A BR 0306589A
Authority
BR
Brazil
Prior art keywords
photoprotein
bioluminescence
improved
improved bioluminescence
calcium
Prior art date
Application number
BR0306589-8A
Other languages
English (en)
Portuguese (pt)
Inventor
Maria Foti
Stefan Lohmer
Original Assignee
Axxam S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Axxam S R L filed Critical Axxam S R L
Publication of BR0306589A publication Critical patent/BR0306589A/pt

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/10Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Dental Preparations (AREA)
BR0306589-8A 2002-10-21 2003-10-21 Fotoproteìna com aperfeiçoada bioluminescência BR0306589A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02023452A EP1413584B1 (en) 2002-10-21 2002-10-21 Photoprotein with improved bioluminescence
PCT/EP2003/011626 WO2004035620A1 (en) 2002-10-21 2003-10-21 Photoprotein with improved bioluminescence

Publications (1)

Publication Number Publication Date
BR0306589A true BR0306589A (pt) 2004-11-30

Family

ID=32049982

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0306589-8A BR0306589A (pt) 2002-10-21 2003-10-21 Fotoproteìna com aperfeiçoada bioluminescência

Country Status (21)

Country Link
US (1) US7601805B2 (enExample)
EP (1) EP1413584B1 (enExample)
JP (1) JP4459058B2 (enExample)
KR (1) KR20050053783A (enExample)
CN (1) CN1317299C (enExample)
AT (1) ATE290016T1 (enExample)
AU (1) AU2003287962B2 (enExample)
BR (1) BR0306589A (enExample)
CA (1) CA2503145A1 (enExample)
DE (1) DE60203123T2 (enExample)
DK (1) DK1413584T3 (enExample)
ES (1) ES2237643T3 (enExample)
HR (1) HRP20050354A2 (enExample)
IL (1) IL168158A (enExample)
MX (1) MXPA05004148A (enExample)
NO (1) NO20051921L (enExample)
PL (1) PL376323A1 (enExample)
RS (1) RS54004A (enExample)
RU (1) RU2340629C2 (enExample)
WO (1) WO2004035620A1 (enExample)
ZA (1) ZA200503197B (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10342670A1 (de) * 2003-09-16 2005-04-21 Bayer Healthcare Ag Isoliertes Photoprotein mtClytin, sowie dessen Verwendung
EP1700865A1 (en) * 2005-03-11 2006-09-13 AXXAM S.r.l. Photoproteins with enhanced bioluminescence and their use as intracellular calcium indicators
WO2007080621A1 (en) * 2006-01-11 2007-07-19 Axxam S.P.A. Luminescent transgenic non human animals, progeny, cell derivatives and uses thereof
EP1808441A1 (en) * 2006-01-11 2007-07-18 AXXAM S.p.A. Luminescent stem cells, transgenic mammals and uses thereof
WO2007143669A2 (en) 2006-06-05 2007-12-13 California Institute Of Technology Real time micro arrays
US8637436B2 (en) 2006-08-24 2014-01-28 California Institute Of Technology Integrated semiconductor bioarray
US11001881B2 (en) 2006-08-24 2021-05-11 California Institute Of Technology Methods for detecting analytes
JP5374840B2 (ja) 2006-07-20 2013-12-25 Jnc株式会社 カルシウム結合発光蛋白質、それをコードする遺伝子およびその用途
US8048626B2 (en) 2006-07-28 2011-11-01 California Institute Of Technology Multiplex Q-PCR arrays
US11525156B2 (en) 2006-07-28 2022-12-13 California Institute Of Technology Multiplex Q-PCR arrays
US11560588B2 (en) 2006-08-24 2023-01-24 California Institute Of Technology Multiplex Q-PCR arrays
GB0625678D0 (en) * 2006-12-21 2007-01-31 Lux Biotechnology Ltd Composition and method for detection of demineralisation
WO2009032218A1 (en) * 2007-08-29 2009-03-12 Biolume Inc. Bioluminescent endoscopy methods and compounds
EP2324127B1 (en) 2008-08-10 2015-01-21 Kuakini Medical Center Method of using foxo3a polymorphisms and haplotypes to predict and promote healthy aging and longevity
SG172321A1 (en) * 2009-01-29 2011-07-28 Commw Scient Ind Res Org Measuring g protein coupled receptor activation
JP5304275B2 (ja) * 2009-01-29 2013-10-02 Jnc株式会社 アポクライティン−iiをコードするコドン最適化核酸およびその使用方法
AU2011323455B2 (en) * 2010-11-02 2017-07-27 Promega Corporation Coelenterazine derivatives and methods of using same
SG10202103336SA (en) * 2010-11-02 2021-04-29 Promega Corp Novel coelenterazine substrates and methods of use
KR20140094442A (ko) 2010-12-24 2014-07-30 오츠카 세이야쿠 가부시키가이샤 생리 활성 물질을 검출하는 바이오어세이법
AU2013204332B2 (en) 2012-04-16 2015-07-16 Commonwealth Scientific And Industrial Research Organisation Methods and systems for detecting an analyte or classifying a sample
JP6588917B2 (ja) 2014-01-29 2019-10-09 プロメガ コーポレイションPromega Corporation 生細胞への適用のためのプロ基質
EP3099683B1 (en) 2014-01-29 2020-08-05 Promega Corporation Quinone-masked probes as labeling reagents for cell uptake measurements
US9708647B2 (en) 2015-03-23 2017-07-18 Insilixa, Inc. Multiplexed analysis of nucleic acid hybridization thermodynamics using integrated arrays
US9499861B1 (en) 2015-09-10 2016-11-22 Insilixa, Inc. Methods and systems for multiplex quantitative nucleic acid amplification
WO2017155858A1 (en) 2016-03-07 2017-09-14 Insilixa, Inc. Nucleic acid sequence identification using solid-phase cyclic single base extension
CN110494569B (zh) 2016-11-14 2024-08-02 联邦科学技术研究组织 蛋白酶传感器分子
GB201700317D0 (en) 2017-01-09 2017-02-22 Calcivis Ltd Detection device
EP3665481B1 (en) 2017-08-08 2023-10-11 PPB Technology Pty Ltd Carbohydrate sensors
US20210155958A1 (en) * 2018-06-13 2021-05-27 Cornell University Bioluminescent markers of neural activity
CN119510370A (zh) 2019-03-14 2025-02-25 因斯利克萨公司 基于时间门控的荧光检测的方法和系统
USD1042180S1 (en) 2020-05-28 2024-09-17 Calcivis Limited Dental detection device
RU2770490C1 (ru) * 2021-07-14 2022-04-18 Федеральное государственное бюджетное научное учреждение "Федеральный исследовательский центр "Красноярский научный центр Сибирского отделения Российской академии наук" Рекомбинантная плазмидная ДНК pET19b-Surv-OL, обеспечивающая синтез гибридного белка сурвивин-обелин (Surv-OL) и гибридный белок, связываемый анти-сурвивин антителами и обладающий биолюминесцентной активностью

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2114175C1 (ru) * 1993-09-14 1998-06-27 Институт белка РАН Способ клонирования нуклеиновых кислот

Also Published As

Publication number Publication date
CN1705680A (zh) 2005-12-07
RU2005111772A (ru) 2005-09-10
DE60203123T2 (de) 2005-07-21
IL168158A (en) 2010-06-16
DE60203123D1 (de) 2005-04-07
WO2004035620A1 (en) 2004-04-29
AU2003287962B2 (en) 2010-06-17
ZA200503197B (en) 2006-06-28
PL376323A1 (en) 2005-12-27
CA2503145A1 (en) 2004-04-29
AU2003287962A1 (en) 2004-05-04
KR20050053783A (ko) 2005-06-08
DK1413584T3 (da) 2005-07-04
US20070065818A1 (en) 2007-03-22
MXPA05004148A (es) 2005-08-03
ATE290016T1 (de) 2005-03-15
JP2006517784A (ja) 2006-08-03
HRP20050354B1 (enExample) 2007-01-31
ES2237643T3 (es) 2005-08-01
EP1413584A1 (en) 2004-04-28
RU2340629C2 (ru) 2008-12-10
CN1317299C (zh) 2007-05-23
NO20051921L (no) 2005-05-23
EP1413584B1 (en) 2005-03-02
HRP20050354A2 (en) 2005-08-31
RS54004A (sr) 2006-10-27
US7601805B2 (en) 2009-10-13
JP4459058B2 (ja) 2010-04-28

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 8A.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2125 DE 27/09/2011.