HRP20040551A2 - Insulin molecule having protracted time action - Google Patents

Insulin molecule having protracted time action Download PDF

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Publication number
HRP20040551A2
HRP20040551A2 HR20040551A HRP20040551A HRP20040551A2 HR P20040551 A2 HRP20040551 A2 HR P20040551A2 HR 20040551 A HR20040551 A HR 20040551A HR P20040551 A HRP20040551 A HR P20040551A HR P20040551 A2 HRP20040551 A2 HR P20040551A2
Authority
HR
Croatia
Prior art keywords
insulin
lys
arg
xaa
homoarginine
Prior art date
Application number
HR20040551A
Other languages
English (en)
Croatian (hr)
Inventor
John Michael Beals
Michael Rosario Defelippis
Richard Dennis Dimarchi
Wayne David Kohn
Radmila Micanovic
Sharon Ruth Myers
Kongman Ng
Lianshan Zhang
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HRP20040551A2 publication Critical patent/HRP20040551A2/hr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Obesity (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
HR20040551A 2001-12-20 2002-12-12 Insulin molecule having protracted time action HRP20040551A2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US34431001P 2001-12-20 2001-12-20
US41460402P 2002-09-27 2002-09-27
PCT/US2002/037601 WO2003053339A2 (en) 2001-12-20 2002-12-12 Insulin molecule having protracted time action

Publications (1)

Publication Number Publication Date
HRP20040551A2 true HRP20040551A2 (en) 2004-10-31

Family

ID=26993857

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20040551A HRP20040551A2 (en) 2001-12-20 2002-12-12 Insulin molecule having protracted time action

Country Status (17)

Country Link
US (1) US20050014679A1 (enExample)
EP (1) EP1545460A4 (enExample)
JP (1) JP2005519041A (enExample)
KR (1) KR20040070237A (enExample)
AU (1) AU2002346490A1 (enExample)
BR (1) BR0215029A (enExample)
CA (1) CA2468100A1 (enExample)
CO (1) CO5590884A2 (enExample)
CZ (1) CZ2004710A3 (enExample)
HR (1) HRP20040551A2 (enExample)
HU (1) HUP0700126A2 (enExample)
IL (1) IL161848A0 (enExample)
MX (1) MXPA04006084A (enExample)
NO (1) NO20042172L (enExample)
PL (1) PL374949A1 (enExample)
SK (1) SK2432004A3 (enExample)
WO (1) WO2003053339A2 (enExample)

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WO2019110625A1 (fr) 2017-12-06 2019-06-13 Adocia Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes
WO2019110773A1 (fr) 2017-12-07 2019-06-13 Adocia Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes
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FR3084585B1 (fr) 2018-08-03 2020-11-06 Adocia Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5 et un compose amphiphile porteur de radicaux hydrophobes
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US20200179489A1 (en) 2018-12-07 2020-06-11 Adocia Injectable solution at ph 7 comprising at least one basal insulin which pi is from 5.8 to 8.5 and a co-polyamino-acid bearing carboxylate charges and hydrophobic radicals and a limited amount of m-cresol
WO2020245470A1 (fr) 2019-06-07 2020-12-10 Adocia Solution injectable a ph 7 comprenant au moins une insuline basale dont le pi est compris entre 5,8 et 8,5, du liraglutide et un co-polyaminoacide porteur de charges carboxylates et de radicaux hydrophobes
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NO20042172L (no) 2004-09-17
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BR0215029A (pt) 2005-12-20
US20050014679A1 (en) 2005-01-20
EP1545460A2 (en) 2005-06-29
KR20040070237A (ko) 2004-08-06
PL374949A1 (en) 2005-11-14
EP1545460A4 (en) 2005-11-16
SK2432004A3 (sk) 2005-04-01
CA2468100A1 (en) 2003-07-03
HUP0700126A2 (en) 2007-06-28
CZ2004710A3 (cs) 2005-02-16
IL161848A0 (en) 2005-11-20
JP2005519041A (ja) 2005-06-30
WO2003053339A2 (en) 2003-07-03
AU2002346490A1 (en) 2003-07-09
WO2003053339A3 (en) 2005-04-14

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