HRP20020231A2 - ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A - Google Patents
ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A Download PDFInfo
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- HRP20020231A2 HRP20020231A2 HR20020231A HRP20020231A HRP20020231A2 HR P20020231 A2 HRP20020231 A2 HR P20020231A2 HR 20020231 A HR20020231 A HR 20020231A HR P20020231 A HRP20020231 A HR P20020231A HR P20020231 A2 HRP20020231 A2 HR P20020231A2
- Authority
- HR
- Croatia
- Prior art keywords
- deoxo
- aza
- homoerythromycin
- methyl
- general formula
- Prior art date
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- MQTOSJVFKKJCRP-BICOPXKESA-N azithromycin Chemical compound O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 MQTOSJVFKKJCRP-BICOPXKESA-N 0.000 title claims abstract description 220
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- 238000000034 method Methods 0.000 claims description 119
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 108
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- 238000002360 preparation method Methods 0.000 claims description 72
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 56
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 52
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- -1 for example Substances 0.000 claims description 33
- SRMPHJKQVUDLQE-KUJJYQHYSA-N azithromycin dihydrate Chemical compound O.O.O([C@@H]1[C@@H](C)C(=O)O[C@@H]([C@@]([C@H](O)[C@@H](C)N(C)C[C@H](C)C[C@@](C)(O)[C@H](O[C@H]2[C@@H]([C@H](C[C@@H](C)O2)N(C)C)O)[C@H]1C)(C)O)CC)[C@H]1C[C@@](C)(OC)[C@@H](O)[C@H](C)O1 SRMPHJKQVUDLQE-KUJJYQHYSA-N 0.000 claims description 31
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- GETQZCLCWQTVFV-UHFFFAOYSA-N trimethylamine Chemical compound CN(C)C GETQZCLCWQTVFV-UHFFFAOYSA-N 0.000 claims description 4
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- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 claims description 3
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Thermal Transfer Or Thermal Recording In General (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
- Finger-Pressure Massage (AREA)
- Instructional Devices (AREA)
Priority Applications (28)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HR20020231A HRP20020231A2 (en) | 2002-03-18 | 2002-03-18 | ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A |
| US10/390,573 US7569549B2 (en) | 2002-03-18 | 2003-03-17 | Isostructural pseudopolymorphs of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin A |
| ARP030100921 AR044525A1 (es) | 2002-03-18 | 2003-03-17 | Seudopolimorfos isoestructurales de 9-deoxo-9a-aza-9a-metil-9a-homoeritromicina "a" |
| HR20040858A HRP20040858A2 (en) | 2002-03-18 | 2003-03-18 | Isostructural pseudopolymorphs of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycina |
| NZ535477A NZ535477A (en) | 2002-03-18 | 2003-03-18 | Isostructural pseudopolymorphs of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin A |
| EP05023731A EP1627883A1 (en) | 2002-03-18 | 2003-03-18 | 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin A derivatives |
| ES03744475T ES2331733T3 (es) | 2002-03-18 | 2003-03-18 | Derivados de 9-desoxo-9a-aza-9a-metil-9a-homoeritromicina a. |
| DE60328872T DE60328872D1 (en) | 2002-03-18 | 2003-03-18 | 9-dexo-9a-aza-9a-methyl-9a-homoerythromycin a derivaten |
| CNA038063263A CN1642966A (zh) | 2002-03-18 | 2003-03-18 | 9－脱氧－9a－氮杂－9a－甲基－9a－高红霉素A的同构假多晶型物 |
| BR0308644-5A BR0308644A (pt) | 2002-03-18 | 2003-03-18 | Pseudopolimorfos isoestruturais de 9-deoxo-9a -aza-9a-metil-homoeritrotromicina a e seus usos |
| AU2003215779A AU2003215779A1 (en) | 2002-03-18 | 2003-03-18 | 9-dexo-9a-aza-9a-methyl-9a-homoerythromycin a derivatives |
| AT03744475T ATE440104T1 (de) | 2002-03-18 | 2003-03-18 | 9-dexo-9a-aza-9a-methyl-9a-homoerythromycin a derivaten |
| EA200401217A EA200401217A1 (ru) | 2002-03-18 | 2003-03-18 | ИЗОСТРУКТУРНЫЕ ПСЕВДОПОЛИМОРФЫ 9-ДЕЗОКСО-9a-АЗА-9a-МЕТИЛ-9a-ГОМОЭРИТРОМИЦИНА A |
| PCT/IB2003/000987 WO2003077830A2 (en) | 2002-03-18 | 2003-03-18 | 9-dexo-9a-aza-9a-methyl-9a-homoerythromycin a derivatives |
| CA002479211A CA2479211A1 (en) | 2002-03-18 | 2003-03-18 | 9-dexo-9a-aza-9a-methyl-9a-homoerythromycin a derivatives |
| YU82504A RS82504A (sr) | 2002-03-18 | 2003-03-18 | Izostrukturni pseudopolimorfi 9-deokso-9a-aza-9a-metil-9a-homoeritromicin a |
| EP03744475A EP1485393B1 (en) | 2002-03-18 | 2003-03-18 | 9-dexo-9a-aza-9a-methyl-9a-homoerythromycin a derivatives |
| JP2003575884A JP2005529082A (ja) | 2002-03-18 | 2003-03-18 | ９−デオキソ−９ａ−アザ−９ａ−メチル−９ａ−ホモエリスロマイシンＡ等構造擬似多形 |
| KR10-2004-7014757A KR20050002872A (ko) | 2002-03-18 | 2003-03-18 | 9-데옥소-9ａ-아자-9ａ-메틸-9ａ-호모에리트로마이신 ａ의동종 구조의 유사 다형질체 |
| PL03372468A PL372468A1 (en) | 2002-03-18 | 2003-03-18 | Isostructural pseudopolymorphs of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a |
| MXPA04009009A MXPA04009009A (es) | 2002-03-18 | 2003-03-18 | Pseudopolimorfos isoestructurales de 9-desoxo-9a-aza-9a-metil-9a-homoeritromicina a. |
| IL16383603A IL163836A0 (en) | 2002-03-18 | 2003-03-18 | Isostructural pseudopolymorphs of 9-deoxo-9A-aza-9-a-methyl-9A-homoerythromycin a |
| DE20321227U DE20321227U1 (de) | 1987-12-29 | 2003-03-18 | Isostrukturelle Pseudopolymorphe von 9-Deoxo-9a-Aza-9a-Methyl-9a-Homoerythromycin A |
| ZA200406971A ZA200406971B (en) | 2002-03-18 | 2004-09-01 | 9-dexo-9a-aza-9a-methyl-9a-homoerythromycin a derivatives. |
| TNP2004000166A TNSN04166A1 (en) | 2002-03-18 | 2004-09-03 | Isostructural pseudopolymorphs of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a |
| BG108874A BG108874A (en) | 2002-03-18 | 2004-09-14 | Isostructural pseudo-polymorphs of 9-deoxo-9a-aza-methyl-9a-homoerythromycin |
| IS7449A IS7449A (is) | 2002-03-18 | 2004-09-16 | Afleiður 9-dexó-9a-asa-9a-metýl-9a-hómóerýþrómýsíns A |
| NO20044341A NO20044341L (no) | 2002-03-18 | 2004-10-13 | Isostrukturelle pseudopolymorfer av 9-deokso-9a-aza-9a-metyl-9a-homoerytromycin |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HR20020231A HRP20020231A2 (en) | 2002-03-18 | 2002-03-18 | ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A |
| US39361202P | 2002-07-03 | 2002-07-03 | |
| US39470502P | 2002-07-08 | 2002-07-08 |
Publications (1)
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|---|---|
| HRP20020231A2 true HRP20020231A2 (en) | 2003-12-31 |
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Family Applications (2)
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| HR20020231A HRP20020231A2 (en) | 1987-12-29 | 2002-03-18 | ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A |
| HR20040858A HRP20040858A2 (en) | 2002-03-18 | 2003-03-18 | Isostructural pseudopolymorphs of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycina |
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| HR20040858A HRP20040858A2 (en) | 2002-03-18 | 2003-03-18 | Isostructural pseudopolymorphs of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycina |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7569549B2 (enExample) |
| EP (2) | EP1485393B1 (enExample) |
| JP (1) | JP2005529082A (enExample) |
| KR (1) | KR20050002872A (enExample) |
| CN (1) | CN1642966A (enExample) |
| AT (1) | ATE440104T1 (enExample) |
| AU (1) | AU2003215779A1 (enExample) |
| BG (1) | BG108874A (enExample) |
| BR (1) | BR0308644A (enExample) |
| CA (1) | CA2479211A1 (enExample) |
| DE (1) | DE60328872D1 (enExample) |
| EA (1) | EA200401217A1 (enExample) |
| ES (1) | ES2331733T3 (enExample) |
| HR (2) | HRP20020231A2 (enExample) |
| IL (1) | IL163836A0 (enExample) |
| IS (1) | IS7449A (enExample) |
| MX (1) | MXPA04009009A (enExample) |
| NO (1) | NO20044341L (enExample) |
| NZ (1) | NZ535477A (enExample) |
| PL (1) | PL372468A1 (enExample) |
| RS (1) | RS82504A (enExample) |
| TN (1) | TNSN04166A1 (enExample) |
| WO (1) | WO2003077830A2 (enExample) |
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| HRP20020231A2 (en) | 2002-03-18 | 2003-12-31 | Pliva D D | ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A |
| HRP20020614A2 (en) | 2002-07-22 | 2004-06-30 | PLIVA-ISTRAŽIVAČKI INSTITUT d.o.o. | Rhombic pseudopolymorph of 9-deoxo-9a-aza-9a-methyl-9a-homoerythromycin a |
| EP1878432A1 (en) * | 2003-07-24 | 2008-01-16 | Pliva - Research and Development Ltd. | Single dose fast dissolving azithromycin |
| DE602004019288D1 (de) * | 2003-07-24 | 2009-03-19 | Pliva Hrvatska D O O | Schnellösliches azithromycin in einzeldosisform |
| WO2005053652A1 (en) | 2003-12-04 | 2005-06-16 | Pfizer Products Inc. | Multiparticulate crystalline drug compositions containing a poloxamer and a glyceride |
| ATE399536T1 (de) * | 2003-12-04 | 2008-07-15 | Pfizer Prod Inc | Verfahren zur herstellung von pharmazeutischen multiteilchenförmigen produkten |
| US6984403B2 (en) * | 2003-12-04 | 2006-01-10 | Pfizer Inc. | Azithromycin dosage forms with reduced side effects |
| AU2004294818A1 (en) * | 2003-12-04 | 2005-06-16 | Pfizer Products Inc. | Azithromycin multiparticulate dosage forms by liquid-based processes |
| EP1689368B1 (en) * | 2003-12-04 | 2016-09-28 | Bend Research, Inc | Spray-congeal process using an extruder for preparing multiparticulate crystalline drug compositions |
| EP1691786A1 (en) | 2003-12-04 | 2006-08-23 | Pfizer Products Inc. | Multiparticulate compositions with improved stability |
| US20060116336A1 (en) * | 2004-03-17 | 2006-06-01 | American Pharmaceutical Partners, Inc. | Lyophilized azithromycin formulation |
| US7468428B2 (en) * | 2004-03-17 | 2008-12-23 | App Pharmaceuticals, Llc | Lyophilized azithromycin formulation |
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| YU43006B (en) | 1981-03-06 | 1989-02-28 | Pliva Pharm & Chem Works | Process for preparing n-methyl-11-aza-10-deoxo-10-dihydro erythromycin and derivatives thereof |
| RU2066324C1 (ru) * | 1987-07-09 | 1996-09-10 | Пфайзер Инк. | Кристаллический дигидрат азитромицина и способ его получения |
| HRP20020231A2 (en) | 2002-03-18 | 2003-12-31 | Pliva D D | ISOSTRUCTURAL PSEUDOPOLYMORPHS OF 9-DEOXO-9a-AZA-9a-METHYL-9a-HOMOERYTHROMYCIN A |
| ATE154806T1 (de) | 1993-05-19 | 1997-07-15 | Pfizer | Zwischenprodukt für azithromycin |
| HRP940251B1 (en) | 1994-04-15 | 1998-12-31 | Stjepan Mutak | Process for the preparation of azithromycin dihydrochloride |
| ES2122905B1 (es) * | 1996-07-11 | 1999-11-16 | Astur Pharma Sa | Sintesis de 11,12-hidrogenoortoborato de 9-desoxo-9a-aza-11,12-desoxi-9a-metil-9a-homoeritromicina a. un procedimiento para la preparacion de 9-desoxo-9a-aza-9a-metil-9a-homoeritromicina a dihidrato (azitromicina dihidrato). |
| PT102130A (pt) | 1998-03-13 | 1999-09-30 | Hovione Sociedade Quimica S A | Processo de preparacao de dihidrato de azitromicina |
| TW546302B (en) * | 1998-05-08 | 2003-08-11 | Biochemie Sa | Improvements in macrolide production |
| CN1205338A (zh) | 1998-05-08 | 1999-01-20 | 刘万忠 | 阿奇霉素水溶性盐的合成新方法及其在医药上的用途 |
| CA2245398C (en) | 1998-08-21 | 2002-01-29 | Apotex Inc. | Azithromycin monohydrate isopropanol clathrate and methods for the manufacture thereof |
| CN100339384C (zh) * | 1998-11-30 | 2007-09-26 | 特瓦制药工业有限公司 | 阿齐霉素的乙醇化物，制备方法以及医药组合物 |
| DE20023815U1 (de) * | 1999-06-29 | 2006-06-08 | Sandoz Ag | Azithromycin enthaltende Zusammensetzungen |
| ES2177373B1 (es) * | 1999-11-26 | 2003-11-01 | Astur Pharma Sa | Preparacion de azitromicina en su forma no cristalina |
| DE60133083D1 (de) | 2000-01-04 | 2008-04-17 | Teva Pharma | Verfahren zur herstellung von azithromycin-dihydrat |
| ES2162764B1 (es) * | 2000-05-17 | 2003-04-01 | Ercros Ind Sa | Forma polimorfica del dihidrato de azitromicina, y su procedimiento deobtencion. |
| CA2417353C (en) | 2000-07-25 | 2009-09-01 | Laboratorio Silanes,S.A. De C.V. | Single-step process for preparing 7,16-deoxy-2-aza-10-o-cladinosil-12-o-desosaminil-4,5-dihydroxi-6-ethyl-3,5,9,11,13,15-hexamethylbicycle (11.2.1)hexadeca-1(2)-en-8-one, and obtaining a new form of 9-deoxo-9a-methyl-9a-aza-9a-homoerythromycin a |
| WO2002015842A2 (en) | 2000-08-23 | 2002-02-28 | Wockhardt Limited | Process for preparation of anhydrous azithromycin |
| HU229488B1 (hu) * | 2000-11-27 | 2014-01-28 | Sandoz Ag | Eljárás makrolid hidrátok elõállítására |
| KR100491183B1 (ko) | 2001-03-21 | 2005-05-25 | 한미약품 주식회사 | 아지트로마이신의 제조방법 및 이 방법에 사용되는9-데옥소-9에이-아자-9에이-호모에리트로마이신 에이의결정성 수화물 |
| KR100431431B1 (ko) | 2001-04-25 | 2004-05-14 | 한미약품 주식회사 | 아지트로마이신 수화물의 1,2-프로필렌글리콜 내포화합물,그의 제조방법 및 그의 약학적 조성물 |
| HRP20010301A2 (en) | 2001-04-27 | 2001-12-31 | Pliva D D | New therapeutic indication for azithromycin in the treatment of non-infective inflammatory diseases |
| US6861413B2 (en) | 2001-05-22 | 2005-03-01 | Pfizer Inc. | Stable non-dihydrate azithromycin oral suspensions |
| GEP20084399B (en) | 2001-05-22 | 2008-06-10 | Pfizer Prod Inc | Crystal forms of azithromycin |
| AU2002353316A1 (en) | 2001-12-21 | 2003-07-09 | Pfizer Products Inc. | Methods for wet granulating azithromycin |
| WO2003053416A1 (en) | 2001-12-21 | 2003-07-03 | Pfizer Products Inc. | Directly compressible formulations of azithromycin |
| RU2283092C2 (ru) | 2002-02-01 | 2006-09-10 | Пфайзер Продактс Инк. | Сухие гранулированные композиции азитромицина |
| ITMI20021209A1 (it) | 2002-06-04 | 2003-12-04 | Chemi Spa | Processo di preparazione di azitromicina ad elevata purezza |
-
2002
- 2002-03-18 HR HR20020231A patent/HRP20020231A2/hr not_active Application Discontinuation
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2003
- 2003-03-17 US US10/390,573 patent/US7569549B2/en not_active Expired - Lifetime
- 2003-03-18 BR BR0308644-5A patent/BR0308644A/pt not_active Application Discontinuation
- 2003-03-18 EP EP03744475A patent/EP1485393B1/en not_active Expired - Lifetime
- 2003-03-18 DE DE60328872T patent/DE60328872D1/de not_active Expired - Fee Related
- 2003-03-18 AT AT03744475T patent/ATE440104T1/de not_active IP Right Cessation
- 2003-03-18 IL IL16383603A patent/IL163836A0/xx unknown
- 2003-03-18 MX MXPA04009009A patent/MXPA04009009A/es not_active Application Discontinuation
- 2003-03-18 HR HR20040858A patent/HRP20040858A2/xx not_active Application Discontinuation
- 2003-03-18 CN CNA038063263A patent/CN1642966A/zh active Pending
- 2003-03-18 EA EA200401217A patent/EA200401217A1/ru unknown
- 2003-03-18 EP EP05023731A patent/EP1627883A1/en not_active Withdrawn
- 2003-03-18 RS YU82504A patent/RS82504A/sr unknown
- 2003-03-18 JP JP2003575884A patent/JP2005529082A/ja not_active Abandoned
- 2003-03-18 WO PCT/IB2003/000987 patent/WO2003077830A2/en not_active Ceased
- 2003-03-18 NZ NZ535477A patent/NZ535477A/en unknown
- 2003-03-18 PL PL03372468A patent/PL372468A1/xx unknown
- 2003-03-18 ES ES03744475T patent/ES2331733T3/es not_active Expired - Lifetime
- 2003-03-18 AU AU2003215779A patent/AU2003215779A1/en not_active Abandoned
- 2003-03-18 CA CA002479211A patent/CA2479211A1/en not_active Abandoned
- 2003-03-18 KR KR10-2004-7014757A patent/KR20050002872A/ko not_active Withdrawn
-
2004
- 2004-09-03 TN TNP2004000166A patent/TNSN04166A1/en unknown
- 2004-09-14 BG BG108874A patent/BG108874A/xx unknown
- 2004-09-16 IS IS7449A patent/IS7449A/is unknown
- 2004-10-13 NO NO20044341A patent/NO20044341L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2005529082A (ja) | 2005-09-29 |
| ES2331733T3 (es) | 2010-01-14 |
| EP1485393B1 (en) | 2009-08-19 |
| IS7449A (is) | 2004-09-16 |
| ATE440104T1 (de) | 2009-09-15 |
| CN1642966A (zh) | 2005-07-20 |
| BR0308644A (pt) | 2005-01-25 |
| US7569549B2 (en) | 2009-08-04 |
| CA2479211A1 (en) | 2003-09-25 |
| MXPA04009009A (es) | 2005-06-17 |
| EP1627883A1 (en) | 2006-02-22 |
| EP1485393A2 (en) | 2004-12-15 |
| NO20044341L (no) | 2004-11-23 |
| AU2003215779A1 (en) | 2003-09-29 |
| IL163836A0 (en) | 2005-12-18 |
| US20040014951A1 (en) | 2004-01-22 |
| WO2003077830A3 (en) | 2004-05-13 |
| TNSN04166A1 (en) | 2007-03-12 |
| RS82504A (sr) | 2006-12-15 |
| KR20050002872A (ko) | 2005-01-10 |
| NZ535477A (en) | 2006-11-30 |
| DE60328872D1 (en) | 2009-10-01 |
| EA200401217A1 (ru) | 2005-02-24 |
| PL372468A1 (en) | 2005-07-25 |
| HRP20040858A2 (en) | 2005-06-30 |
| WO2003077830A2 (en) | 2003-09-25 |
| BG108874A (en) | 2005-12-30 |
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