HN2006014095A - Forma cristalina ortorrombica del maleato de asenapina - Google Patents

Forma cristalina ortorrombica del maleato de asenapina

Info

Publication number
HN2006014095A
HN2006014095A HN2006014095A HN2006014095A HN2006014095A HN 2006014095 A HN2006014095 A HN 2006014095A HN 2006014095 A HN2006014095 A HN 2006014095A HN 2006014095 A HN2006014095 A HN 2006014095A HN 2006014095 A HN2006014095 A HN 2006014095A
Authority
HN
Honduras
Prior art keywords
orthromby
crystal form
asenapine maleate
asenapine
maleate
Prior art date
Application number
HN2006014095A
Other languages
English (en)
Inventor
Johannes Heeres Gerardus
Original Assignee
Organon Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36617328&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HN2006014095(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Organon Nv filed Critical Organon Nv
Publication of HN2006014095A publication Critical patent/HN2006014095A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

La invencion se refiere a una nueva forma cristalina de asenapina, a metodos para su preparacion y a composiciones farmaceuticas que comprenden dicha forma cristalina.
HN2006014095A 2005-04-07 2006-04-06 Forma cristalina ortorrombica del maleato de asenapina HN2006014095A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP05102742 2005-04-07
EP05102969 2005-04-14

Publications (1)

Publication Number Publication Date
HN2006014095A true HN2006014095A (es) 2010-08-19

Family

ID=36617328

Family Applications (1)

Application Number Title Priority Date Filing Date
HN2006014095A HN2006014095A (es) 2005-04-07 2006-04-06 Forma cristalina ortorrombica del maleato de asenapina

Country Status (31)

Country Link
EP (2) EP1710245B1 (es)
JP (1) JP5058151B2 (es)
KR (1) KR101422843B1 (es)
AR (1) AR056306A1 (es)
AT (2) ATE370954T1 (es)
AU (1) AU2006231617B2 (es)
BR (1) BRPI0609741A8 (es)
CA (1) CA2603509C (es)
CY (2) CY1106902T1 (es)
DE (2) DE602006004463D1 (es)
DK (2) DK1917267T3 (es)
DO (1) DOP2006000082A (es)
ES (2) ES2318742T3 (es)
GT (1) GT200600135A (es)
HN (1) HN2006014095A (es)
HR (1) HRP20070429T3 (es)
IL (1) IL186355A (es)
MX (1) MX2007012445A (es)
MY (1) MY137969A (es)
NO (1) NO340520B1 (es)
NZ (1) NZ562124A (es)
PE (1) PE20061311A1 (es)
PL (2) PL1917267T3 (es)
PT (2) PT1917267E (es)
RS (1) RS50532B (es)
RU (1) RU2405786C2 (es)
SI (2) SI1710245T1 (es)
SV (1) SV2006002473A (es)
TW (1) TWI364423B (es)
UY (1) UY29459A1 (es)
WO (1) WO2006106135A1 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2007002891A1 (es) * 2006-10-06 2008-04-18 Organon Nv Trans-5-cloro-2-metil-2,3,3a,12b-tetrahidro-1h-dibenz-[2,3:6,7]oxepino[4,5-c]pirrol 50% amorfo en base al peso total del compuesto; procedimiento de preparacion; composicion farmaceutica; y uso para el tratamiento de un trastorno seleccionado entre e
AR077225A1 (es) * 2009-06-24 2011-08-10 Organon Nv Formulaciones inyectables que contienen asenapina y metodo de tratamiento que las utiliza
WO2011159903A2 (en) * 2010-06-18 2011-12-22 Dr. Reddy's Laboratories Ltd. Asenapine maleate
WO2012066565A2 (en) * 2010-11-16 2012-05-24 Cadila Healthcare Limited Asenapine maleate amorphous and crystalline form and process for preparation thereof
EP2468750A1 (en) 2010-12-13 2012-06-27 Chemo Ibérica, S.A. Polymorphic forms of asenapine maleate and processes for their preparation
WO2012123325A1 (en) 2011-03-11 2012-09-20 Medichem S.A. NEW CRYSTAL FORMS OF THE SALT OF TRANS-5-CHLORO-2-METHYL-2,3,3A,12b-TETRAHYDRO-1H-DIBENZO[2,3:6,7]OXEPINO[4,5-c]PYRROLE WITH MALEIC ACID
ITMI20110734A1 (it) * 2011-05-02 2012-11-03 Olon Spa Sali cristallini di asenapina
EP2524919A1 (en) 2011-05-17 2012-11-21 Sandoz AG Novel crystalline salts of Asenapine with organic Di-acids and Tri-acids
EP2524920A1 (en) 2011-05-17 2012-11-21 Sandoz AG Novel Crystalline Asenapine Hydrochloride Salt Forms
EP2524921A1 (en) 2011-05-17 2012-11-21 Sandoz AG Novel Crystalline Salts of Asenapine
EP2709616B1 (en) * 2011-05-18 2018-01-24 Laboratorios Lesvi, S.L. Synthesis of a stable micronised monoclinic form of asenapine maleate
US9533994B2 (en) 2011-05-18 2017-01-03 Laboratorios Lesvi S.L. Monoclinic crystalline form of asenapine maleate with a specific particle size distribution
WO2013041604A1 (en) 2011-09-21 2013-03-28 Sandoz Ag Crystal form of asenapine maleate
EP2572703A1 (en) 2011-09-21 2013-03-27 Hexal AG Compressed oral dosage form for asenapine maleate
CN104507472B (zh) * 2012-07-26 2016-10-05 久光制药株式会社 贴附剂
ITMI20121810A1 (it) 2012-10-24 2014-04-25 Chemo Iberica Sa Poliformi di maleato di asenapina e processo per la loro preparazione
WO2014090386A1 (en) 2012-12-11 2014-06-19 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Orally disintegrating tablet containing asenapine
WO2014127786A1 (en) 2013-02-22 2014-08-28 Zentiva, K.S. Orally disintegrating pharmaceutical composition comprising asenapine
EP3350194A4 (en) 2015-09-02 2019-04-24 Eloxx Pharmaceuticals Ltd. AMINO-LIKES DERIVATIVES AND USES THEREOF FOR THE TREATMENT OF GENETIC DISEASES
AU2017384392B2 (en) 2016-12-20 2023-05-25 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing asenapine and polysiloxane or polyisobutylene
JP7236389B2 (ja) 2016-12-20 2023-03-09 エルテーエス ローマン テラピー－ジステーメ アーゲー アセナピンを含有する経皮治療システム
EP3644973B1 (en) 2017-06-26 2021-03-24 LTS LOHMANN Therapie-Systeme AG Transdermal therapeutic system containing asenapine and silicone acrylic hybrid polymer
BR112020026099A2 (pt) 2018-06-20 2021-03-23 Lts Lohmann Therapie-Systeme Ag sistema terapêutico transdérmico que contém asenapina

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7605526A (nl) * 1976-05-24 1977-11-28 Akzo Nv Nieuwe tetracyclische derivaten.
HU225051B1 (en) * 1994-03-02 2006-05-29 Organon Ireland Ltd Sublingual or buccal pharmaceutical compositions containing trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1h-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole
WO1999032108A1 (en) * 1997-12-19 1999-07-01 Akzo Nobel N.V. Org-5222 in the treatment of depression
TWI327915B (en) * 2003-06-12 2010-08-01 Organon Nv Pharmaceutical composition comprising antipsychotic agent and use of the antipsychotic agent for treating patients with overweight

Also Published As

Publication number Publication date
SV2006002473A (es) 2009-11-24
IL186355A0 (en) 2008-01-20
RU2405786C2 (ru) 2010-12-10
DE602006004463D1 (de) 2009-02-05
EP1917267A1 (en) 2008-05-07
CA2603509A1 (en) 2006-10-12
BRPI0609741A2 (pt) 2010-04-27
TW200722428A (en) 2007-06-16
PL1710245T3 (pl) 2008-01-31
PL1917267T3 (pl) 2009-06-30
BRPI0609741A8 (pt) 2018-03-13
CA2603509C (en) 2013-12-03
HRP20070429T3 (en) 2007-11-30
EP1710245B1 (en) 2007-08-22
RS50532B (sr) 2010-05-07
JP2008534656A (ja) 2008-08-28
EP1710245A1 (en) 2006-10-11
NZ562124A (en) 2010-07-30
ES2293626T3 (es) 2008-03-16
MY137969A (en) 2009-04-30
EP1917267B1 (en) 2008-12-24
JP5058151B2 (ja) 2012-10-24
MX2007012445A (es) 2007-11-07
DOP2006000082A (es) 2006-11-30
ES2318742T3 (es) 2009-05-01
AR056306A1 (es) 2007-10-03
AU2006231617A1 (en) 2006-10-12
NO340520B1 (no) 2017-05-02
SI1710245T1 (sl) 2007-12-31
DK1917267T3 (da) 2009-04-14
PT1917267E (pt) 2009-02-04
CY1106902T1 (el) 2012-09-26
ATE418556T1 (de) 2009-01-15
DE602006000080T2 (de) 2008-05-15
KR20080005253A (ko) 2008-01-10
GT200600135A (es) 2006-11-07
RU2007141198A (ru) 2009-05-20
CY1108742T1 (el) 2014-04-09
DK1710245T3 (da) 2007-12-03
PT1710245E (pt) 2007-10-03
UY29459A1 (es) 2006-11-30
TWI364423B (en) 2012-05-21
WO2006106135A1 (en) 2006-10-12
ATE370954T1 (de) 2007-09-15
PE20061311A1 (es) 2007-02-09
SI1917267T1 (sl) 2009-04-30
IL186355A (en) 2016-05-31
DE602006000080D1 (de) 2007-10-04
NO20075142L (no) 2007-11-05
AU2006231617B2 (en) 2010-06-03
KR101422843B1 (ko) 2014-07-24

Similar Documents

Publication Publication Date Title
HN2006014095A (es) Forma cristalina ortorrombica del maleato de asenapina
NO20091395L (no) Nye tiofenderivater
NO20082793L (no) Nye tiofenderivater
NI201100170A (es) Inhibidores de epoxicetonas proteasa de tripéptidos cristalinos
HN2008001393A (es) Derivados de 1,2,4,5- tetrahidro -3h- benzazepinas, su procedimiento de preparacion y las composiciones farmaceuticas que las contienen
EA201200506A1 (ru) СПОСОБ ПОЛУЧЕНИЯ КРИСТАЛЛИЧЕСКОЙ ФОРМЫ 1-ХЛОР-4-(β-D-ГЛЮКОПИРАНОЗ-1-ИЛ)-2-(4-((S)-ТЕТРАГИДРОФУРАН-3-ИЛОКСИ)БЕНЗИЛ)БЕНЗОЛА
PA8657801A1 (es) Aminalcoholes triciclicos, procedimientos para su preparacion
HN2008001191A (es) Compuestos de biciclolactama sustituida
ECSP10010295A (es) Formulacion de anticuerpo
UY31484A1 (es) Piperidinas heteroaril-sustituidas
MA32369B1 (fr) Composes de benzene sulfonamide thiazole et oxazole
PA8660301A1 (es) Pirazolo piridinas sustituidas, composiciones que las contienen, procedimiento de fabricacion y utilizacion
DOP2012000150A (es) Triazolopiridinas
SV2009002858A (es) Nueva forma polimorfica y la forma amorfa de 5- cloro-n-([(5s)-2-oxo-3-[4-(3-oxo-4-morfolinil)-fenil]-1,3-oxazolidin-5-il]-metil)-2-tiofenocarboxamida
BRPI0514833A (pt) fenilaminotiazóis substituìdos e seu uso
CR9723A (es) Nueva forma cristalina de un derivado de piridazino[4,5-b] indol
DOP2005000025A (es) Compuestos de heteroaril- y fenilsulfamoilo sustituidos
AR051043A1 (es) Forma cristalina de clorhidrato de (3-cian-1h-indol-7il)-[4-(4-fluorofenetil)-piperazin-1-il]-metanona
CR11423A (es) NUEVOS INHIBIDORES DE sEH Y SU USO
EA201401193A1 (ru) Триарильные соединения и композиции, их содержащие
GT200500130A (es) Forma cristalina alfa del ranelato de estroncio, procedimiento para su preparacion y composiciones farmaceuticas que la contienen
CL2008000585A1 (es) Compuestos derivados de nicotinamida; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar una enfermedad mediada por prostaglandina d2 producida por h-pgds.
EA201101116A1 (ru) Фармацевтические композиции, включающие производные 2-оксо-1-пирролидина
EA201101118A1 (ru) Фармацевтические композиции, включающие производные 2-оксо-1-пирролидина
HN2010001537A (es) Nuevos derivados dihidroindolonas, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen