PL1710245T3 - Postać krystaliczna maleinianu asenapiny - Google Patents

Postać krystaliczna maleinianu asenapiny

Info

Publication number
PL1710245T3
PL1710245T3 PL06112332T PL06112332T PL1710245T3 PL 1710245 T3 PL1710245 T3 PL 1710245T3 PL 06112332 T PL06112332 T PL 06112332T PL 06112332 T PL06112332 T PL 06112332T PL 1710245 T3 PL1710245 T3 PL 1710245T3
Authority
PL
Poland
Prior art keywords
crystal form
asenapine maleate
asenapine
maleate
crystal
Prior art date
Application number
PL06112332T
Other languages
English (en)
Inventor
Gerhardus Johannes Heeres
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36617328&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1710245(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of PL1710245T3 publication Critical patent/PL1710245T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
PL06112332T 2005-04-07 2006-04-06 Postać krystaliczna maleinianu asenapiny PL1710245T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05102742 2005-04-07
EP05102969 2005-04-14
EP06112332A EP1710245B1 (en) 2005-04-07 2006-04-06 Crystal form of asenapine maleate

Publications (1)

Publication Number Publication Date
PL1710245T3 true PL1710245T3 (pl) 2008-01-31

Family

ID=36617328

Family Applications (2)

Application Number Title Priority Date Filing Date
PL06725622T PL1917267T3 (pl) 2005-04-07 2006-04-06 Postać krystaliczna maleinianu asenapiny
PL06112332T PL1710245T3 (pl) 2005-04-07 2006-04-06 Postać krystaliczna maleinianu asenapiny

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL06725622T PL1917267T3 (pl) 2005-04-07 2006-04-06 Postać krystaliczna maleinianu asenapiny

Country Status (31)

Country Link
EP (2) EP1710245B1 (pl)
JP (1) JP5058151B2 (pl)
KR (1) KR101422843B1 (pl)
AR (1) AR056306A1 (pl)
AT (2) ATE370954T1 (pl)
AU (1) AU2006231617B2 (pl)
BR (1) BRPI0609741A8 (pl)
CA (1) CA2603509C (pl)
CY (2) CY1106902T1 (pl)
DE (2) DE602006004463D1 (pl)
DK (2) DK1917267T3 (pl)
DO (1) DOP2006000082A (pl)
ES (2) ES2318742T3 (pl)
GT (1) GT200600135A (pl)
HN (1) HN2006014095A (pl)
HR (1) HRP20070429T3 (pl)
IL (1) IL186355A (pl)
MX (1) MX2007012445A (pl)
MY (1) MY137969A (pl)
NO (1) NO340520B1 (pl)
NZ (1) NZ562124A (pl)
PE (1) PE20061311A1 (pl)
PL (2) PL1917267T3 (pl)
PT (2) PT1917267E (pl)
RS (1) RS50532B (pl)
RU (1) RU2405786C2 (pl)
SI (2) SI1710245T1 (pl)
SV (1) SV2006002473A (pl)
TW (1) TWI364423B (pl)
UY (1) UY29459A1 (pl)
WO (1) WO2006106135A1 (pl)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CL2007002891A1 (es) * 2006-10-06 2008-04-18 Organon Nv Trans-5-cloro-2-metil-2,3,3a,12b-tetrahidro-1h-dibenz-[2,3:6,7]oxepino[4,5-c]pirrol 50% amorfo en base al peso total del compuesto; procedimiento de preparacion; composicion farmaceutica; y uso para el tratamiento de un trastorno seleccionado entre e
AR077225A1 (es) * 2009-06-24 2011-08-10 Organon Nv Formulaciones inyectables que contienen asenapina y metodo de tratamiento que las utiliza
WO2011159903A2 (en) * 2010-06-18 2011-12-22 Dr. Reddy's Laboratories Ltd. Asenapine maleate
WO2012066565A2 (en) * 2010-11-16 2012-05-24 Cadila Healthcare Limited Asenapine maleate amorphous and crystalline form and process for preparation thereof
EP2468750A1 (en) 2010-12-13 2012-06-27 Chemo Ibérica, S.A. Polymorphic forms of asenapine maleate and processes for their preparation
WO2012123325A1 (en) 2011-03-11 2012-09-20 Medichem S.A. NEW CRYSTAL FORMS OF THE SALT OF TRANS-5-CHLORO-2-METHYL-2,3,3A,12b-TETRAHYDRO-1H-DIBENZO[2,3:6,7]OXEPINO[4,5-c]PYRROLE WITH MALEIC ACID
ITMI20110734A1 (it) * 2011-05-02 2012-11-03 Olon Spa Sali cristallini di asenapina
EP2524919A1 (en) 2011-05-17 2012-11-21 Sandoz AG Novel crystalline salts of Asenapine with organic Di-acids and Tri-acids
EP2524920A1 (en) 2011-05-17 2012-11-21 Sandoz AG Novel Crystalline Asenapine Hydrochloride Salt Forms
EP2524921A1 (en) 2011-05-17 2012-11-21 Sandoz AG Novel Crystalline Salts of Asenapine
EP2709616B1 (en) * 2011-05-18 2018-01-24 Laboratorios Lesvi, S.L. Synthesis of a stable micronised monoclinic form of asenapine maleate
US9533994B2 (en) 2011-05-18 2017-01-03 Laboratorios Lesvi S.L. Monoclinic crystalline form of asenapine maleate with a specific particle size distribution
WO2013041604A1 (en) 2011-09-21 2013-03-28 Sandoz Ag Crystal form of asenapine maleate
EP2572703A1 (en) 2011-09-21 2013-03-27 Hexal AG Compressed oral dosage form for asenapine maleate
CN104507472B (zh) * 2012-07-26 2016-10-05 久光制药株式会社 贴附剂
ITMI20121810A1 (it) 2012-10-24 2014-04-25 Chemo Iberica Sa Poliformi di maleato di asenapina e processo per la loro preparazione
WO2014090386A1 (en) 2012-12-11 2014-06-19 Alfred E. Tiefenbacher (Gmbh & Co. Kg) Orally disintegrating tablet containing asenapine
WO2014127786A1 (en) 2013-02-22 2014-08-28 Zentiva, K.S. Orally disintegrating pharmaceutical composition comprising asenapine
EP3350194A4 (en) 2015-09-02 2019-04-24 Eloxx Pharmaceuticals Ltd. AMINO-LIKES DERIVATIVES AND USES THEREOF FOR THE TREATMENT OF GENETIC DISEASES
AU2017384392B2 (en) 2016-12-20 2023-05-25 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing asenapine and polysiloxane or polyisobutylene
JP7236389B2 (ja) 2016-12-20 2023-03-09 エルテーエス ローマン テラピー-ジステーメ アーゲー アセナピンを含有する経皮治療システム
EP3644973B1 (en) 2017-06-26 2021-03-24 LTS LOHMANN Therapie-Systeme AG Transdermal therapeutic system containing asenapine and silicone acrylic hybrid polymer
BR112020026099A2 (pt) 2018-06-20 2021-03-23 Lts Lohmann Therapie-Systeme Ag sistema terapêutico transdérmico que contém asenapina

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7605526A (nl) * 1976-05-24 1977-11-28 Akzo Nv Nieuwe tetracyclische derivaten.
HU225051B1 (en) * 1994-03-02 2006-05-29 Organon Ireland Ltd Sublingual or buccal pharmaceutical compositions containing trans-5-chloro-2-methyl-2,3,3a,12b-tetrahydro-1h-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole
WO1999032108A1 (en) * 1997-12-19 1999-07-01 Akzo Nobel N.V. Org-5222 in the treatment of depression
TWI327915B (en) * 2003-06-12 2010-08-01 Organon Nv Pharmaceutical composition comprising antipsychotic agent and use of the antipsychotic agent for treating patients with overweight

Also Published As

Publication number Publication date
SV2006002473A (es) 2009-11-24
IL186355A0 (en) 2008-01-20
HN2006014095A (es) 2010-08-19
RU2405786C2 (ru) 2010-12-10
DE602006004463D1 (de) 2009-02-05
EP1917267A1 (en) 2008-05-07
CA2603509A1 (en) 2006-10-12
BRPI0609741A2 (pt) 2010-04-27
TW200722428A (en) 2007-06-16
PL1917267T3 (pl) 2009-06-30
BRPI0609741A8 (pt) 2018-03-13
CA2603509C (en) 2013-12-03
HRP20070429T3 (en) 2007-11-30
EP1710245B1 (en) 2007-08-22
RS50532B (sr) 2010-05-07
JP2008534656A (ja) 2008-08-28
EP1710245A1 (en) 2006-10-11
NZ562124A (en) 2010-07-30
ES2293626T3 (es) 2008-03-16
MY137969A (en) 2009-04-30
EP1917267B1 (en) 2008-12-24
JP5058151B2 (ja) 2012-10-24
MX2007012445A (es) 2007-11-07
DOP2006000082A (es) 2006-11-30
ES2318742T3 (es) 2009-05-01
AR056306A1 (es) 2007-10-03
AU2006231617A1 (en) 2006-10-12
NO340520B1 (no) 2017-05-02
SI1710245T1 (sl) 2007-12-31
DK1917267T3 (da) 2009-04-14
PT1917267E (pt) 2009-02-04
CY1106902T1 (el) 2012-09-26
ATE418556T1 (de) 2009-01-15
DE602006000080T2 (de) 2008-05-15
KR20080005253A (ko) 2008-01-10
GT200600135A (es) 2006-11-07
RU2007141198A (ru) 2009-05-20
CY1108742T1 (el) 2014-04-09
DK1710245T3 (da) 2007-12-03
PT1710245E (pt) 2007-10-03
UY29459A1 (es) 2006-11-30
TWI364423B (en) 2012-05-21
WO2006106135A1 (en) 2006-10-12
ATE370954T1 (de) 2007-09-15
PE20061311A1 (es) 2007-02-09
SI1917267T1 (sl) 2009-04-30
IL186355A (en) 2016-05-31
DE602006000080D1 (de) 2007-10-04
NO20075142L (no) 2007-11-05
AU2006231617B2 (en) 2010-06-03
KR101422843B1 (ko) 2014-07-24

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