HK886A - PROCESS FOR THE RESOLUTION OF d,l 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID; A MIXTURE OF THE SALTS OF THESE d AND l ACIDS; A PHARMACEUTICAL COMPOSITION CONTAINING A SALT OF THE d ACID; A SALT OF THE d ACID - Google Patents

PROCESS FOR THE RESOLUTION OF d,l 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID; A MIXTURE OF THE SALTS OF THESE d AND l ACIDS; A PHARMACEUTICAL COMPOSITION CONTAINING A SALT OF THE d ACID; A SALT OF THE d ACID

Info

Publication number
HK886A
HK886A HK8/86A HK886A HK886A HK 886 A HK886 A HK 886A HK 8/86 A HK8/86 A HK 8/86A HK 886 A HK886 A HK 886A HK 886 A HK886 A HK 886A
Authority
HK
Hong Kong
Prior art keywords
methoxy
naphthyl
propionic acid
glucamine
salt
Prior art date
Application number
HK8/86A
Other languages
German (de)
English (en)
French (fr)
Inventor
Percy George Holton
Original Assignee
Syntex Pharmaceuticals International Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26734026&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK886(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/097,118 external-priority patent/US4246193A/en
Application filed by Syntex Pharmaceuticals International Limited filed Critical Syntex Pharmaceuticals International Limited
Publication of HK886A publication Critical patent/HK886A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/50—Use of additives, e.g. for stabilisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C07C57/40—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic containing condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK8/86A 1979-07-06 1986-01-02 PROCESS FOR THE RESOLUTION OF d,l 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID; A MIXTURE OF THE SALTS OF THESE d AND l ACIDS; A PHARMACEUTICAL COMPOSITION CONTAINING A SALT OF THE d ACID; A SALT OF THE d ACID HK886A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5525879A 1979-07-06 1979-07-06
US06/097,118 US4246193A (en) 1979-11-26 1979-11-26 Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid

Publications (1)

Publication Number Publication Date
HK886A true HK886A (en) 1986-01-10

Family

ID=26734026

Family Applications (1)

Application Number Title Priority Date Filing Date
HK8/86A HK886A (en) 1979-07-06 1986-01-02 PROCESS FOR THE RESOLUTION OF d,l 2-(6-METHOXY-2-NAPHTHYL)PROPIONIC ACID; A MIXTURE OF THE SALTS OF THESE d AND l ACIDS; A PHARMACEUTICAL COMPOSITION CONTAINING A SALT OF THE d ACID; A SALT OF THE d ACID

Country Status (27)

Country Link
EP (1) EP0022529B1 (enrdf_load_stackoverflow)
JP (2) JPS63313749A (enrdf_load_stackoverflow)
KR (1) KR830000769B1 (enrdf_load_stackoverflow)
AR (1) AR225927A1 (enrdf_load_stackoverflow)
AU (1) AU544963B2 (enrdf_load_stackoverflow)
CA (1) CA1135717A (enrdf_load_stackoverflow)
CZ (1) CZ277725B6 (enrdf_load_stackoverflow)
DD (1) DD153367A5 (enrdf_load_stackoverflow)
DE (3) DE3063969D1 (enrdf_load_stackoverflow)
DK (2) DK156051C (enrdf_load_stackoverflow)
ES (1) ES8105691A1 (enrdf_load_stackoverflow)
FR (2) FR2472557A1 (enrdf_load_stackoverflow)
GB (1) GB2054579B (enrdf_load_stackoverflow)
GR (1) GR68796B (enrdf_load_stackoverflow)
HK (1) HK886A (enrdf_load_stackoverflow)
IE (1) IE50000B1 (enrdf_load_stackoverflow)
IL (1) IL60498A (enrdf_load_stackoverflow)
IN (1) IN152737B (enrdf_load_stackoverflow)
IT (1) IT1130490B (enrdf_load_stackoverflow)
MY (1) MY8600452A (enrdf_load_stackoverflow)
NZ (1) NZ194237A (enrdf_load_stackoverflow)
PH (4) PH15674A (enrdf_load_stackoverflow)
PL (1) PL133439B1 (enrdf_load_stackoverflow)
PT (1) PT71486A (enrdf_load_stackoverflow)
RO (1) RO80655B (enrdf_load_stackoverflow)
SK (1) SK278340B6 (enrdf_load_stackoverflow)
YU (1) YU42673B (enrdf_load_stackoverflow)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1168387B (it) * 1981-04-01 1987-05-20 Alfa Farmaceutici Spa Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico
ZA828453B (en) * 1981-12-08 1983-12-28 Boots Co Plc Therapeutic agents
IT1196197B (it) * 1984-07-23 1988-11-10 Ravizza Spa Procedimento per la risoluzione dell'acido (+)(-) 2-(2'-(p-fluorofenil)--5'-benzossazolil)-propionico
GB9121279D0 (en) * 1991-10-08 1991-11-20 Cerestar Holding Bv Process for the production of aminopolyols
US5574183A (en) * 1995-01-24 1996-11-12 Albemarle Corporation Preparation of optically active aliphatic carboxylic acids
KR100678287B1 (ko) * 2005-06-23 2007-02-02 한미약품 주식회사 클로피도그렐의 제조방법 및 이에 사용되는 중간체
KR101170537B1 (ko) * 2010-01-11 2012-08-01 김창운 해수의 자연순환이 가능한 내륙 내 바다양식 수조

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid
DE1668654B2 (de) * 1967-01-13 1976-11-04 Syntex Corp., Panama 2-(6'-substituierte-2'-naphthyl)- propionsaeuren und -derivate, ihre herstellung und sie enthaltende arzneimittel
ZA70809B (en) * 1969-03-24 1971-09-29 Syntex Corp Amine salts of 2-(6'-methoxy-2'-naphthyl)propionic acids and processes for the preparation thereof
US3686183A (en) * 1969-03-24 1972-08-22 Syntex Corp Preparation of optical isomers of arylalkylacetic acids
US3904683A (en) * 1972-08-10 1975-09-09 Syntex Corp Process for the resolution of d- and 1-2-(6-methoxy-2-naphthyl) propionic acid
GR64816B (en) * 1977-03-08 1980-06-03 Boots Co Ltd Resolution of flurbiprofen ii/iii
CH641432A5 (de) * 1978-07-19 1984-02-29 Syntex Pharma Int Verfahren zur aufspaltung von racemischer 6-methoxy-alpha-methyl-2-naphthalinessigsaeure in die optischen antipoden.

Also Published As

Publication number Publication date
AR225927A1 (es) 1982-05-14
DK156051B (da) 1989-06-19
PH16432A (en) 1983-10-03
CA1135717A (en) 1982-11-16
FR2470108A1 (fr) 1981-05-29
GR68796B (enrdf_load_stackoverflow) 1982-02-18
YU174380A (en) 1984-04-30
IT1130490B (it) 1986-06-11
IL60498A (en) 1984-06-29
ES493126A0 (es) 1981-06-16
RO80655B (ro) 1983-04-30
KR830000769B1 (ko) 1983-04-11
RO80655A (ro) 1983-04-29
PH16431A (en) 1983-10-03
DK156051C (da) 1989-11-06
NZ194237A (en) 1984-05-31
DE3051036C2 (enrdf_load_stackoverflow) 1988-03-31
AU544963B2 (en) 1985-06-27
PH15674A (en) 1983-03-11
GB2054579B (en) 1983-06-22
IT8068053A0 (it) 1980-07-03
PH16328A (en) 1983-09-05
JPH0249749A (ja) 1990-02-20
DE3063969D1 (en) 1983-08-04
MY8600452A (en) 1986-12-31
EP0022529A1 (en) 1981-01-21
DD153367A5 (de) 1982-01-06
PT71486A (en) 1980-08-01
FR2472557B1 (enrdf_load_stackoverflow) 1984-04-20
DK289080A (da) 1981-01-07
AU6012180A (en) 1981-01-15
ES8105691A1 (es) 1981-06-16
SK278340B6 (en) 1996-12-04
DK239988D0 (da) 1988-05-03
GB2054579A (en) 1981-02-18
PL225474A1 (enrdf_load_stackoverflow) 1981-03-27
IE50000B1 (en) 1986-01-22
JPH0321535B2 (enrdf_load_stackoverflow) 1991-03-22
IL60498A0 (en) 1980-09-16
EP0022529B1 (en) 1983-06-29
IN152737B (enrdf_load_stackoverflow) 1984-03-24
DE3025448C2 (enrdf_load_stackoverflow) 1987-05-21
IE801396L (en) 1981-01-06
DE3025448A1 (de) 1981-01-15
JPH0454B2 (enrdf_load_stackoverflow) 1992-01-06
YU42673B (en) 1988-10-31
DK239988A (da) 1988-05-03
PL133439B1 (en) 1985-06-29
CZ277725B6 (en) 1993-04-14
FR2472557A1 (fr) 1981-07-03
CS477480A3 (en) 1992-11-18
FR2470108B1 (enrdf_load_stackoverflow) 1984-04-20
JPS63313749A (ja) 1988-12-21

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