DK239988A - Anvendelse af en blanding af d,1-2-(6-methoxy-2-naphthyl) propionsyre med en optisk aktiv base til fremstilling af d-2-(6-methoxy-2-naphtyl)-propionsyre - Google Patents

Anvendelse af en blanding af d,1-2-(6-methoxy-2-naphthyl) propionsyre med en optisk aktiv base til fremstilling af d-2-(6-methoxy-2-naphtyl)-propionsyre

Info

Publication number
DK239988A
DK239988A DK239988A DK239988A DK239988A DK 239988 A DK239988 A DK 239988A DK 239988 A DK239988 A DK 239988A DK 239988 A DK239988 A DK 239988A DK 239988 A DK239988 A DK 239988A
Authority
DK
Denmark
Prior art keywords
methoxy
propionic acid
naphtyl
naphthyl
mixture
Prior art date
Application number
DK239988A
Other languages
English (en)
Other versions
DK239988D0 (da
Inventor
Percy G Holton
Original Assignee
Syntex Pharma Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26734026&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK239988(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/097,118 external-priority patent/US4246193A/en
Application filed by Syntex Pharma Int filed Critical Syntex Pharma Int
Publication of DK239988D0 publication Critical patent/DK239988D0/da
Publication of DK239988A publication Critical patent/DK239988A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/50Use of additives, e.g. for stabilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/487Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C07C57/40Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic containing condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK239988A 1979-07-06 1988-05-03 Anvendelse af en blanding af d,1-2-(6-methoxy-2-naphthyl) propionsyre med en optisk aktiv base til fremstilling af d-2-(6-methoxy-2-naphtyl)-propionsyre DK239988A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5525879A 1979-07-06 1979-07-06
US06/097,118 US4246193A (en) 1979-11-26 1979-11-26 Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid

Publications (2)

Publication Number Publication Date
DK239988D0 DK239988D0 (da) 1988-05-03
DK239988A true DK239988A (da) 1988-05-03

Family

ID=26734026

Family Applications (2)

Application Number Title Priority Date Filing Date
DK289080A DK156051C (da) 1979-07-06 1980-07-04 Fremgangsmaade til separering af d-2-(6-methoxy-2-naphthyl)-propionsyre fra en blanding af d- og 1-2-(6-methoxy-2-naphthyl)-propionsyre
DK239988A DK239988A (da) 1979-07-06 1988-05-03 Anvendelse af en blanding af d,1-2-(6-methoxy-2-naphthyl) propionsyre med en optisk aktiv base til fremstilling af d-2-(6-methoxy-2-naphtyl)-propionsyre

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK289080A DK156051C (da) 1979-07-06 1980-07-04 Fremgangsmaade til separering af d-2-(6-methoxy-2-naphthyl)-propionsyre fra en blanding af d- og 1-2-(6-methoxy-2-naphthyl)-propionsyre

Country Status (27)

Country Link
EP (1) EP0022529B1 (da)
JP (2) JPS63313749A (da)
KR (1) KR830000769B1 (da)
AR (1) AR225927A1 (da)
AU (1) AU544963B2 (da)
CA (1) CA1135717A (da)
CZ (1) CZ277725B6 (da)
DD (1) DD153367A5 (da)
DE (3) DE3063969D1 (da)
DK (2) DK156051C (da)
ES (1) ES493126A0 (da)
FR (2) FR2472557A1 (da)
GB (1) GB2054579B (da)
GR (1) GR68796B (da)
HK (1) HK886A (da)
IE (1) IE50000B1 (da)
IL (1) IL60498A (da)
IN (1) IN152737B (da)
IT (1) IT1130490B (da)
MY (1) MY8600452A (da)
NZ (1) NZ194237A (da)
PH (4) PH15674A (da)
PL (1) PL133439B1 (da)
PT (1) PT71486A (da)
RO (1) RO80655B (da)
SK (1) SK278340B6 (da)
YU (1) YU42673B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1168387B (it) * 1981-04-01 1987-05-20 Alfa Farmaceutici Spa Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico
ZA828453B (en) * 1981-12-08 1983-12-28 Boots Co Plc Therapeutic agents
IT1196197B (it) * 1984-07-23 1988-11-10 Ravizza Spa Procedimento per la risoluzione dell'acido (+)(-) 2-(2'-(p-fluorofenil)--5'-benzossazolil)-propionico
GB9121279D0 (en) * 1991-10-08 1991-11-20 Cerestar Holding Bv Process for the production of aminopolyols
US5574183A (en) * 1995-01-24 1996-11-12 Albemarle Corporation Preparation of optically active aliphatic carboxylic acids
KR100678287B1 (ko) * 2005-06-23 2007-02-02 한미약품 주식회사 클로피도그렐의 제조방법 및 이에 사용되는 중간체
KR101170537B1 (ko) * 2010-01-11 2012-08-01 김창운 해수의 자연순환이 가능한 내륙 내 바다양식 수조

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid
DE1668654B2 (de) * 1967-01-13 1976-11-04 Syntex Corp., Panama 2-(6'-substituierte-2'-naphthyl)- propionsaeuren und -derivate, ihre herstellung und sie enthaltende arzneimittel
ZA70809B (en) * 1969-03-24 1971-09-29 Syntex Corp Amine salts of 2-(6'-methoxy-2'-naphthyl)propionic acids and processes for the preparation thereof
US3686183A (en) * 1969-03-24 1972-08-22 Syntex Corp Preparation of optical isomers of arylalkylacetic acids
US3904683A (en) * 1972-08-10 1975-09-09 Syntex Corp Process for the resolution of d- and 1-2-(6-methoxy-2-naphthyl) propionic acid
CS222255B2 (en) * 1977-03-08 1983-06-24 Boots Co Ltd Method of increasing the portion of the deisred anantiometer in the acid component of the 2-arylpropion acid
CH641432A5 (de) * 1978-07-19 1984-02-29 Syntex Pharma Int Verfahren zur aufspaltung von racemischer 6-methoxy-alpha-methyl-2-naphthalinessigsaeure in die optischen antipoden.

Also Published As

Publication number Publication date
DE3051036C2 (da) 1988-03-31
AU6012180A (en) 1981-01-15
GR68796B (da) 1982-02-18
CZ277725B6 (en) 1993-04-14
RO80655A (ro) 1983-04-29
IT8068053A0 (it) 1980-07-03
EP0022529A1 (en) 1981-01-21
CS477480A3 (en) 1992-11-18
ES8105691A1 (es) 1981-06-16
MY8600452A (en) 1986-12-31
JPS63313749A (ja) 1988-12-21
HK886A (en) 1986-01-10
FR2470108B1 (da) 1984-04-20
DK239988D0 (da) 1988-05-03
NZ194237A (en) 1984-05-31
JPH0249749A (ja) 1990-02-20
PH16432A (en) 1983-10-03
IL60498A (en) 1984-06-29
DE3025448A1 (de) 1981-01-15
FR2472557A1 (fr) 1981-07-03
YU174380A (en) 1984-04-30
PT71486A (en) 1980-08-01
RO80655B (ro) 1983-04-30
DK156051C (da) 1989-11-06
DE3025448C2 (da) 1987-05-21
JPH0454B2 (da) 1992-01-06
DD153367A5 (de) 1982-01-06
AU544963B2 (en) 1985-06-27
GB2054579A (en) 1981-02-18
PH16431A (en) 1983-10-03
IT1130490B (it) 1986-06-11
EP0022529B1 (en) 1983-06-29
PH16328A (en) 1983-09-05
FR2472557B1 (da) 1984-04-20
SK278340B6 (en) 1996-12-04
DK156051B (da) 1989-06-19
PL225474A1 (da) 1981-03-27
CA1135717A (en) 1982-11-16
DE3063969D1 (en) 1983-08-04
IN152737B (da) 1984-03-24
GB2054579B (en) 1983-06-22
IE50000B1 (en) 1986-01-22
YU42673B (en) 1988-10-31
PH15674A (en) 1983-03-11
JPH0321535B2 (da) 1991-03-22
FR2470108A1 (fr) 1981-05-29
PL133439B1 (en) 1985-06-29
DK289080A (da) 1981-01-07
IL60498A0 (en) 1980-09-16
AR225927A1 (es) 1982-05-14
IE801396L (en) 1981-01-06
ES493126A0 (es) 1981-06-16
KR830000769B1 (ko) 1983-04-11

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