PH15674A - Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid - Google Patents

Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid

Info

Publication number
PH15674A
PH15674A PH24217A PH24217A PH15674A PH 15674 A PH15674 A PH 15674A PH 24217 A PH24217 A PH 24217A PH 24217 A PH24217 A PH 24217A PH 15674 A PH15674 A PH 15674A
Authority
PH
Philippines
Prior art keywords
naphthyl
methoxy
resolution
propionic acid
propionic
Prior art date
Application number
PH24217A
Other languages
English (en)
Inventor
Percy George Holton
Original Assignee
Syntex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26734026&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PH15674(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/097,118 external-priority patent/US4246193A/en
Application filed by Syntex Corp filed Critical Syntex Corp
Publication of PH15674A publication Critical patent/PH15674A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/50Use of additives, e.g. for stabilisation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42Separation; Purification; Stabilisation; Use of additives
    • C07C51/487Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C07C57/40Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic containing condensed ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PH24217A 1979-07-06 1980-07-01 Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid PH15674A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5525879A 1979-07-06 1979-07-06
US06/097,118 US4246193A (en) 1979-11-26 1979-11-26 Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid

Publications (1)

Publication Number Publication Date
PH15674A true PH15674A (en) 1983-03-11

Family

ID=26734026

Family Applications (4)

Application Number Title Priority Date Filing Date
PH24217A PH15674A (en) 1979-07-06 1980-07-01 Process for the resolution of d,1 2-(6-methoxy-2-naphthyl)propionic acid
PH25636A PH16432A (en) 1979-07-06 1981-05-15 Pharmaceutical composition containing a salt of d-2-(6-methoxy-2-naphthyl)propionic acid and use thereof
PH25633A PH16431A (en) 1979-07-06 1981-05-15 Mixture of the n-r-d-glucamine salts of d and 1 2-(6-methoxy-2-naphthyl)propionic acid
PH25634A PH16328A (en) 1979-07-06 1981-05-15 Pharmaceutical composition containing a salt of d-2-(6-methoxy-2-naphthyl)propionic acid and use thereof

Family Applications After (3)

Application Number Title Priority Date Filing Date
PH25636A PH16432A (en) 1979-07-06 1981-05-15 Pharmaceutical composition containing a salt of d-2-(6-methoxy-2-naphthyl)propionic acid and use thereof
PH25633A PH16431A (en) 1979-07-06 1981-05-15 Mixture of the n-r-d-glucamine salts of d and 1 2-(6-methoxy-2-naphthyl)propionic acid
PH25634A PH16328A (en) 1979-07-06 1981-05-15 Pharmaceutical composition containing a salt of d-2-(6-methoxy-2-naphthyl)propionic acid and use thereof

Country Status (27)

Country Link
EP (1) EP0022529B1 (da)
JP (2) JPS63313749A (da)
KR (1) KR830000769B1 (da)
AR (1) AR225927A1 (da)
AU (1) AU544963B2 (da)
CA (1) CA1135717A (da)
CZ (1) CZ277725B6 (da)
DD (1) DD153367A5 (da)
DE (3) DE3063969D1 (da)
DK (2) DK156051C (da)
ES (1) ES8105691A1 (da)
FR (2) FR2472557A1 (da)
GB (1) GB2054579B (da)
GR (1) GR68796B (da)
HK (1) HK886A (da)
IE (1) IE50000B1 (da)
IL (1) IL60498A (da)
IN (1) IN152737B (da)
IT (1) IT1130490B (da)
MY (1) MY8600452A (da)
NZ (1) NZ194237A (da)
PH (4) PH15674A (da)
PL (1) PL133439B1 (da)
PT (1) PT71486A (da)
RO (1) RO80655B (da)
SK (1) SK278340B6 (da)
YU (1) YU42673B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1168387B (it) * 1981-04-01 1987-05-20 Alfa Farmaceutici Spa Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico
ZA828453B (en) * 1981-12-08 1983-12-28 Boots Co Plc Therapeutic agents
IT1196197B (it) * 1984-07-23 1988-11-10 Ravizza Spa Procedimento per la risoluzione dell'acido (+)(-) 2-(2'-(p-fluorofenil)--5'-benzossazolil)-propionico
GB9121279D0 (en) * 1991-10-08 1991-11-20 Cerestar Holding Bv Process for the production of aminopolyols
US5574183A (en) * 1995-01-24 1996-11-12 Albemarle Corporation Preparation of optically active aliphatic carboxylic acids
KR100678287B1 (ko) * 2005-06-23 2007-02-02 한미약품 주식회사 클로피도그렐의 제조방법 및 이에 사용되는 중간체
KR101170537B1 (ko) * 2010-01-11 2012-08-01 김창운 해수의 자연순환이 가능한 내륙 내 바다양식 수조

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1668654B2 (de) * 1967-01-13 1976-11-04 Syntex Corp., Panama 2-(6'-substituierte-2'-naphthyl)- propionsaeuren und -derivate, ihre herstellung und sie enthaltende arzneimittel
US3904682A (en) * 1967-01-13 1975-09-09 Syntex Corp 2-(6{40 -Methoxy-2{40 -naphthyl)acetic acid
US3686183A (en) * 1969-03-24 1972-08-22 Syntex Corp Preparation of optical isomers of arylalkylacetic acids
ZA70809B (en) * 1969-03-24 1971-09-29 Syntex Corp Amine salts of 2-(6'-methoxy-2'-naphthyl)propionic acids and processes for the preparation thereof
US3904683A (en) * 1972-08-10 1975-09-09 Syntex Corp Process for the resolution of d- and 1-2-(6-methoxy-2-naphthyl) propionic acid
CS222255B2 (en) * 1977-03-08 1983-06-24 Boots Co Ltd Method of increasing the portion of the deisred anantiometer in the acid component of the 2-arylpropion acid
CH641432A5 (de) * 1978-07-19 1984-02-29 Syntex Pharma Int Verfahren zur aufspaltung von racemischer 6-methoxy-alpha-methyl-2-naphthalinessigsaeure in die optischen antipoden.

Also Published As

Publication number Publication date
DE3025448A1 (de) 1981-01-15
PT71486A (en) 1980-08-01
ES493126A0 (es) 1981-06-16
JPH0454B2 (da) 1992-01-06
DE3063969D1 (en) 1983-08-04
DK156051C (da) 1989-11-06
GB2054579B (en) 1983-06-22
AU6012180A (en) 1981-01-15
FR2470108B1 (da) 1984-04-20
RO80655B (ro) 1983-04-30
JPS63313749A (ja) 1988-12-21
GB2054579A (en) 1981-02-18
CZ277725B6 (en) 1993-04-14
IL60498A (en) 1984-06-29
DD153367A5 (de) 1982-01-06
ES8105691A1 (es) 1981-06-16
EP0022529B1 (en) 1983-06-29
RO80655A (ro) 1983-04-29
CA1135717A (en) 1982-11-16
DE3051036C2 (da) 1988-03-31
FR2470108A1 (fr) 1981-05-29
EP0022529A1 (en) 1981-01-21
DK289080A (da) 1981-01-07
IL60498A0 (en) 1980-09-16
KR830000769B1 (ko) 1983-04-11
PH16432A (en) 1983-10-03
PH16328A (en) 1983-09-05
PL225474A1 (da) 1981-03-27
YU42673B (en) 1988-10-31
CS477480A3 (en) 1992-11-18
IE50000B1 (en) 1986-01-22
IT8068053A0 (it) 1980-07-03
AU544963B2 (en) 1985-06-27
PL133439B1 (en) 1985-06-29
NZ194237A (en) 1984-05-31
HK886A (en) 1986-01-10
IT1130490B (it) 1986-06-11
GR68796B (da) 1982-02-18
DE3025448C2 (da) 1987-05-21
SK278340B6 (en) 1996-12-04
DK156051B (da) 1989-06-19
PH16431A (en) 1983-10-03
DK239988A (da) 1988-05-03
MY8600452A (en) 1986-12-31
AR225927A1 (es) 1982-05-14
JPH0321535B2 (da) 1991-03-22
DK239988D0 (da) 1988-05-03
FR2472557A1 (fr) 1981-07-03
IN152737B (da) 1984-03-24
YU174380A (en) 1984-04-30
FR2472557B1 (da) 1984-04-20
JPH0249749A (ja) 1990-02-20
IE801396L (en) 1981-01-06

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