HK78696A - Cyclosporins - Google Patents

Cyclosporins

Info

Publication number
HK78696A
HK78696A HK78696A HK78696A HK78696A HK 78696 A HK78696 A HK 78696A HK 78696 A HK78696 A HK 78696A HK 78696 A HK78696 A HK 78696A HK 78696 A HK78696 A HK 78696A
Authority
HK
Hong Kong
Prior art keywords
cyclosporins
cyclosporine
succinimidooxysuccinyl
conjugates
cyclosporin
Prior art date
Application number
HK78696A
Other languages
English (en)
Inventor
Joachim Rosenthaler
Roland Wenger
Philipp E Ball
Max H Schreier
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848425040A external-priority patent/GB8425040D0/en
Priority claimed from GB858515673A external-priority patent/GB8515673D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of HK78696A publication Critical patent/HK78696A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
HK78696A 1984-10-04 1996-05-02 Cyclosporins HK78696A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848425040A GB8425040D0 (en) 1984-10-04 1984-10-04 Organic compounds
GB858515673A GB8515673D0 (en) 1985-06-20 1985-06-20 Organic compounds

Publications (1)

Publication Number Publication Date
HK78696A true HK78696A (en) 1996-05-10

Family

ID=26288301

Family Applications (2)

Application Number Title Priority Date Filing Date
HK78696A HK78696A (en) 1984-10-04 1996-05-02 Cyclosporins
HK124696A HK124696A (en) 1984-10-04 1996-07-11 Monoclonal antibodies to cyclosporings

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK124696A HK124696A (en) 1984-10-04 1996-07-11 Monoclonal antibodies to cyclosporings

Country Status (15)

Country Link
EP (4) EP0314862A1 (xx)
JP (1) JPH074269B2 (xx)
KR (1) KR910002691B1 (xx)
AT (1) ATE92501T1 (xx)
AU (4) AU589917B2 (xx)
CA (1) CA1309671C (xx)
CY (2) CY1915A (xx)
DE (2) DE3587342T2 (xx)
DK (1) DK172037B1 (xx)
ES (1) ES8702949A1 (xx)
FI (1) FI93965C (xx)
HK (2) HK78696A (xx)
NO (1) NO173557C (xx)
NZ (1) NZ213680A (xx)
WO (1) WO1986002080A1 (xx)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5239057A (en) * 1987-03-27 1993-08-24 Abbott Laboratories Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies
US5427960A (en) * 1987-03-27 1995-06-27 Abbott Laboratories Fluorescence polarization assay for cyclosporin A and metabolites and related immunogens and antibodies
EP0283801A3 (en) * 1987-03-27 1990-05-30 Abbott Laboratories Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies
US5698448A (en) * 1988-12-02 1997-12-16 Soldin; Steven J. Immunosuppressive drug binding proteins and use
JPH04502328A (ja) * 1988-12-05 1992-04-23 ザ・トラステイーズ・オブ・コロンビア・ユニヴアーシテイ・イン・ザ・シテイ・オブ・ニユー・ヨーク シクロスポリンａの新規誘導体、それに対する抗体及びその使用
GB8916901D0 (en) 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds
ES2084069T3 (es) * 1990-08-15 1996-05-01 Abbott Lab Reactivos de inmunoensayo y metodo para la determinacion de ciclosporina.
CA2048302A1 (en) * 1990-08-15 1992-02-16 Victoria P. Meucci Solubilization reagent for biological test samples
DE69133095T2 (de) 1990-11-20 2003-03-27 Dade Behring Marburg Gmbh Cyclosporin-Immunoassay
GB9307491D0 (en) 1993-04-08 1993-06-02 Sandoz Ltd Organic compounds
USRE40596E1 (en) * 1993-04-08 2008-12-02 Novartis Ag Rapamycin assay
AU9203898A (en) * 1997-08-26 1999-03-16 Wisconsin Alumni Research Foundation Cyclosporin a conjugates and uses therefor
US6270957B1 (en) 1997-08-26 2001-08-07 Wisconsin Alumni Research Foundation Non-Imuunosuppressive cyclosporins and their use in the prevention and treatment of HIV infection
US5990274A (en) * 1997-11-25 1999-11-23 Dade Behring Inc. Cyclosporine derivatives and uses thereof
JP4350898B2 (ja) 1998-07-01 2009-10-21 デビオファーム・ソシエテ・アノニム 活性の特徴が改善された新規のシクロスポリン
US6686454B1 (en) 1998-10-09 2004-02-03 Isotechnika, Inc. Antibodies to specific regions of cyclosporine related compounds
AU763822B2 (en) 1998-10-09 2003-07-31 Isotechnika, Inc. Methods for the production of antibodies to specific regions of cyclosporine and cyclosporine metabolites
PL210795B1 (pl) 2001-10-19 2012-03-30 Isotechnika Inc Sposób wytwarzania mieszaniny ISATX247 wzbogaconej w izomer (E), sposób wytwarzania mieszaniny ISATX247 wzbogaconej w izomer (Z), sposób stereoselektywnej syntezy izomeru (E) ISATX247, sposób stereoselektywnej syntezy izomeru (Z) ISATX247 i sposób wytwarzania mieszaniny izomerów ISATX247
JP5174898B2 (ja) 2007-05-24 2013-04-03 アボット・ラボラトリーズ 疎水性薬物検体代謝産物との交差反応性が低下している免疫アッセイ
TW200932240A (en) 2007-10-25 2009-08-01 Astellas Pharma Inc Pharmaceutical composition containing lipophilic substance which inhibits IL-2 production
CA2910133C (en) * 2008-05-23 2018-02-27 The University Of British Columbia Modified drugs for use in liposomal nanoparticles
WO2010088573A1 (en) 2009-01-30 2010-08-05 Enanta Pharmaceuticals, Inc. Cyclosporin analogues for preventing or treating hepatitis c infection
US8481483B2 (en) 2009-02-19 2013-07-09 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8367053B2 (en) 2009-07-09 2013-02-05 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8349312B2 (en) 2009-07-09 2013-01-08 Enanta Pharmaceuticals, Inc. Proline substituted cyclosporin analogues
US8685917B2 (en) 2009-07-09 2014-04-01 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8623814B2 (en) 2010-02-23 2014-01-07 Enanta Pharmaceuticals, Inc. Antiviral agents
US9428845B1 (en) 2010-12-28 2016-08-30 Warp Drive Bio, Inc. Identifying new therapeutic agents
WO2012145427A1 (en) 2011-04-18 2012-10-26 The Trustees Of Columbia University In The City Of New York Methods to treat cancer using cyclosporine and cyclosporine derivatives
US8906853B2 (en) 2012-11-28 2014-12-09 Enanta Pharmaceuticals, Inc. [N-Me-4-hydroxyleucine]-9-cyclosporin analogues for treatment and prevention of hepatitis C infection
AU2014311346A1 (en) 2013-08-26 2016-03-17 Enanta Pharmaceuticals, Inc. Cyclosporin analogues for preventing or treating hepatitis C
WO2016073480A1 (en) 2014-11-03 2016-05-12 Enanta Pharmaceuticals, Inc. Novel cyclosporin analogues for preventing or treating hepatitis c infection
EP4289950A3 (en) 2015-01-09 2024-01-24 Revolution Medicines, Inc. Macrocyclic compounds that participate in cooperative binding and medical uses thereof
US9989535B2 (en) * 2015-10-01 2018-06-05 Warp Drive Bio, Inc. Methods and reagents for analyzing protein-protein interfaces
MA44680A (fr) 2016-04-12 2019-02-20 Warp Drive Bio Inc Compositions et procédés pour la production de composés
WO2018081592A2 (en) 2016-10-28 2018-05-03 Warp Drive Bio, Inc. Compositions and methods for the production of compounds
MX2022005360A (es) 2019-11-04 2022-06-02 Revolution Medicines Inc Inhibidores de ras.
CR20220240A (es) 2019-11-04 2022-08-03 Revolution Medicines Inc Inhibidores de ras
JP2022553858A (ja) 2019-11-04 2022-12-26 レボリューション メディシンズ インコーポレイテッド Ｒａｓ阻害剤
JP2023541916A (ja) 2020-09-15 2023-10-04 レボリューション メディシンズ インコーポレイテッド がんの治療における、ｒａｓ阻害剤としてのインドール誘導体

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB211526A (en) 1922-09-22 1924-02-22 John Fletcher Holliday Improvements in and relating to chain grate stokers
CH614931A5 (xx) 1975-11-04 1979-12-28 Sandoz Ag
US4210581A (en) 1975-11-04 1980-07-01 Sandoz Ltd. Organic compounds
DE2819094A1 (de) 1977-05-10 1978-11-23 Sandoz Ag Cyclosporin-derivate, ihre verwendung und herstellung
EP0034567B1 (en) * 1980-02-14 1984-11-07 Sandoz Ag A method for the total synthesis of cyclosporins and novel cyclosporins
IL62965A0 (en) 1980-07-17 1981-07-31 Scripps Miles Lab Inc Monoclonal antibodies to drugs and theri production
EP0056782B1 (en) 1981-01-09 1984-08-01 Sandoz Ag Novel cyclosporins
GB8407618D0 (en) 1984-03-23 1984-05-02 Sandoz Ltd Organic compounds
CH667274A5 (de) 1984-03-23 1988-09-30 Sandoz Ag Cyclosporine, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen.

Also Published As

Publication number Publication date
AU3914389A (en) 1989-11-16
EP0198026A1 (en) 1986-10-22
CY1927A (en) 1997-05-16
NO173557C (no) 1993-12-29
JPS62500383A (ja) 1987-02-19
CY1915A (en) 1985-09-27
KR870700637A (ko) 1987-12-30
KR910002691B1 (ko) 1991-05-03
DK261386A (da) 1986-06-03
HK124696A (en) 1996-07-19
NZ213680A (en) 1990-05-28
FI93965C (fi) 1995-06-26
EP0314861A1 (en) 1989-05-10
DK172037B1 (da) 1997-09-22
AU589917B2 (en) 1989-10-26
EP0314862A1 (en) 1989-05-10
CA1309671C (en) 1992-11-03
DK261386D0 (da) 1986-06-03
FI93965B (fi) 1995-03-15
ES8702949A1 (es) 1987-01-16
NO173557B (no) 1993-09-20
EP0290762B1 (en) 1993-05-12
DE3587505D1 (de) 1993-09-09
DE3587342D1 (en) 1993-06-17
DE3587505T2 (de) 1994-01-05
NO862177L (no) 1986-08-04
AU4967185A (en) 1986-04-17
ATE92501T1 (de) 1993-08-15
EP0198026B1 (en) 1993-08-04
EP0290762A1 (en) 1988-11-17
JPH074269B2 (ja) 1995-01-25
ES547495A0 (es) 1987-01-16
DE3587342T2 (de) 1993-12-02
AU3914189A (en) 1989-11-16
WO1986002080A1 (en) 1986-04-10
AU3914289A (en) 1989-10-26
NO862177D0 (no) 1986-06-02
FI862370A (fi) 1986-06-03
FI862370A0 (fi) 1986-06-03

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Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20050926