ES547495A0 - Procedimiento para la produccion de anticuerpos monoclonales a ciclosporinas. - Google Patents

Procedimiento para la produccion de anticuerpos monoclonales a ciclosporinas.

Info

Publication number
ES547495A0
ES547495A0 ES547495A ES547495A ES547495A0 ES 547495 A0 ES547495 A0 ES 547495A0 ES 547495 A ES547495 A ES 547495A ES 547495 A ES547495 A ES 547495A ES 547495 A0 ES547495 A0 ES 547495A0
Authority
ES
Spain
Prior art keywords
cyclosporins
monoclonal antibodies
procedure
production
cyclosporine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES547495A
Other languages
English (en)
Other versions
ES8702949A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB848425040A external-priority patent/GB8425040D0/en
Priority claimed from GB858515673A external-priority patent/GB8515673D0/en
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES547495A0 publication Critical patent/ES547495A0/es
Publication of ES8702949A1 publication Critical patent/ES8702949A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicinal Preparation (AREA)
ES547495A 1984-10-04 1985-10-02 Procedimiento para la produccion de anticuerpos monoclonales a ciclosporinas. Expired ES8702949A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB848425040A GB8425040D0 (en) 1984-10-04 1984-10-04 Organic compounds
GB858515673A GB8515673D0 (en) 1985-06-20 1985-06-20 Organic compounds

Publications (2)

Publication Number Publication Date
ES547495A0 true ES547495A0 (es) 1987-01-16
ES8702949A1 ES8702949A1 (es) 1987-01-16

Family

ID=26288301

Family Applications (1)

Application Number Title Priority Date Filing Date
ES547495A Expired ES8702949A1 (es) 1984-10-04 1985-10-02 Procedimiento para la produccion de anticuerpos monoclonales a ciclosporinas.

Country Status (15)

Country Link
EP (4) EP0314861A1 (es)
JP (1) JPH074269B2 (es)
KR (1) KR910002691B1 (es)
AT (1) ATE92501T1 (es)
AU (4) AU589917B2 (es)
CA (1) CA1309671C (es)
CY (2) CY1915A (es)
DE (2) DE3587342T2 (es)
DK (1) DK172037B1 (es)
ES (1) ES8702949A1 (es)
FI (1) FI93965C (es)
HK (2) HK78696A (es)
NO (1) NO173557C (es)
NZ (1) NZ213680A (es)
WO (1) WO1986002080A1 (es)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5239057A (en) * 1987-03-27 1993-08-24 Abbott Laboratories Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies
EP0283801A3 (en) * 1987-03-27 1990-05-30 Abbott Laboratories Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies
US5427960A (en) * 1987-03-27 1995-06-27 Abbott Laboratories Fluorescence polarization assay for cyclosporin A and metabolites and related immunogens and antibodies
US5698448A (en) * 1988-12-02 1997-12-16 Soldin; Steven J. Immunosuppressive drug binding proteins and use
WO1990006763A1 (en) * 1988-12-05 1990-06-28 The Trustees Of Columbia University In The City Of New York Novel derivatives of cyclosporine a, antibodies directed thereto and uses thereof
GB8916901D0 (en) 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds
ES2084069T3 (es) * 1990-08-15 1996-05-01 Abbott Lab Reactivos de inmunoensayo y metodo para la determinacion de ciclosporina.
CA2048302A1 (en) * 1990-08-15 1992-02-16 Victoria P. Meucci Solubilization reagent for biological test samples
DE69121844T2 (de) 1990-11-20 1997-01-23 Behringwerke Ag Immunotest für Cyclosporin
GB9307491D0 (en) 1993-04-08 1993-06-02 Sandoz Ltd Organic compounds
USRE40596E1 (en) * 1993-04-08 2008-12-02 Novartis Ag Rapamycin assay
US6270957B1 (en) 1997-08-26 2001-08-07 Wisconsin Alumni Research Foundation Non-Imuunosuppressive cyclosporins and their use in the prevention and treatment of HIV infection
US6316405B1 (en) 1997-08-26 2001-11-13 Wisconsin Alumni Research Foundation Cyclosporin a conjugates and uses therefor
US5990274A (en) 1997-11-25 1999-11-23 Dade Behring Inc. Cyclosporine derivatives and uses thereof
DK1091975T3 (da) 1998-07-01 2006-04-18 Debiopharm Sa Ny cyclosporin med forbedret aktivitetsprofil
CN1319105A (zh) 1998-10-09 2001-10-24 伊索技术公司 制备针对环孢菌素及其代谢物特异性区域的抗体的方法
US6686454B1 (en) 1998-10-09 2004-02-03 Isotechnika, Inc. Antibodies to specific regions of cyclosporine related compounds
PT1436321E (pt) 2001-10-19 2006-10-31 Isotechnika Inc Sintese de analogos de ciclosporina
ATE535813T1 (de) 2007-05-24 2011-12-15 Abbott Lab Reduzierte kreuzreaktivität mit hydrophoben arzneistoffanalyt-stoffwechselprodukten zeigende immuntestverfahren
TW200932240A (en) 2007-10-25 2009-08-01 Astellas Pharma Inc Pharmaceutical composition containing lipophilic substance which inhibits IL-2 production
CN104622809B (zh) * 2008-05-23 2019-04-19 英属哥伦比亚大学 用于脂质体纳米颗粒的修饰的药物
EP2391376A4 (en) 2009-01-30 2012-08-01 Enanta Pharm Inc ANALOGUES OF CYCLOSPORIN FOR PREVENTING OR TREATING HEPATITIS C INFECTION
US8481483B2 (en) 2009-02-19 2013-07-09 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8367053B2 (en) 2009-07-09 2013-02-05 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8685917B2 (en) 2009-07-09 2014-04-01 Enanta Pharmaceuticals, Inc. Cyclosporin analogues
US8349312B2 (en) 2009-07-09 2013-01-08 Enanta Pharmaceuticals, Inc. Proline substituted cyclosporin analogues
US8623814B2 (en) 2010-02-23 2014-01-07 Enanta Pharmaceuticals, Inc. Antiviral agents
US9428845B1 (en) 2010-12-28 2016-08-30 Warp Drive Bio, Inc. Identifying new therapeutic agents
WO2012145427A1 (en) 2011-04-18 2012-10-26 The Trustees Of Columbia University In The City Of New York Methods to treat cancer using cyclosporine and cyclosporine derivatives
WO2014085623A1 (en) 2012-11-28 2014-06-05 Enanta Pharmaceuticals, Inc. Novel [n-me-4-hydroxyleucine]-9-cyclosporin analogues
JP2016538317A (ja) 2013-08-26 2016-12-08 エナンタ ファーマシューティカルズ インコーポレイテッド Ｃ型肝炎を防止または治療するための新規シクロスポリン類似体
US9669095B2 (en) 2014-11-03 2017-06-06 Enanta Pharmaceuticals, Inc. Cyclosporin analogues for preventing or treating hepatitis C infection
US10533016B2 (en) 2015-01-09 2020-01-14 Revolution Medicines, Inc. Compounds that participate in cooperative binding and uses thereof
EP4242304A3 (en) * 2015-10-01 2024-02-07 Revolution Medicines, Inc. Methods and reagents for analyzing protein-protein interfaces
US10907188B2 (en) 2016-04-12 2021-02-02 Ginkgo Bioworks, Inc. Compositions and methods for the production of compounds
CA3042231A1 (en) 2016-10-28 2018-05-03 Ginkgo Bioworks, Inc. Compositions and methods for the production of compounds
JP2022553859A (ja) 2019-11-04 2022-12-26 レボリューション メディシンズ インコーポレイテッド Ｒａｓ阻害剤
TW202132315A (zh) 2019-11-04 2021-09-01 美商銳新醫藥公司 Ras 抑制劑
BR112022008565A2 (pt) 2019-11-04 2022-08-09 Revolution Medicines Inc Composto, composição farmacêutica, conjugado, métodos para tratar câncer e um distúrbio relativo à proteína ras
EP4214209A1 (en) 2020-09-15 2023-07-26 Revolution Medicines, Inc. Indole derivatives as ras inhibitors in the treatment of cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB211526A (en) 1922-09-22 1924-02-22 John Fletcher Holliday Improvements in and relating to chain grate stokers
CH614931A5 (es) * 1975-11-04 1979-12-28 Sandoz Ag
US4210581A (en) 1975-11-04 1980-07-01 Sandoz Ltd. Organic compounds
DE2819094A1 (de) 1977-05-10 1978-11-23 Sandoz Ag Cyclosporin-derivate, ihre verwendung und herstellung
EP0034567B1 (en) 1980-02-14 1984-11-07 Sandoz Ag A method for the total synthesis of cyclosporins and novel cyclosporins
IL62965A0 (en) 1980-07-17 1981-07-31 Scripps Miles Lab Inc Monoclonal antibodies to drugs and theri production
US4384996A (en) * 1981-01-09 1983-05-24 Sandoz Ltd. Novel cyclosporins
GB8407618D0 (en) 1984-03-23 1984-05-02 Sandoz Ltd Organic compounds
CH667274A5 (de) 1984-03-23 1988-09-30 Sandoz Ag Cyclosporine, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen.

Also Published As

Publication number Publication date
DK261386D0 (da) 1986-06-03
EP0290762A1 (en) 1988-11-17
JPS62500383A (ja) 1987-02-19
NO173557B (no) 1993-09-20
CA1309671C (en) 1992-11-03
EP0198026A1 (en) 1986-10-22
CY1915A (en) 1985-09-27
CY1927A (en) 1997-05-16
EP0314862A1 (en) 1989-05-10
JPH074269B2 (ja) 1995-01-25
DE3587505T2 (de) 1994-01-05
KR870700637A (ko) 1987-12-30
ATE92501T1 (de) 1993-08-15
DE3587342D1 (en) 1993-06-17
EP0314861A1 (en) 1989-05-10
EP0198026B1 (en) 1993-08-04
EP0290762B1 (en) 1993-05-12
AU3914289A (en) 1989-10-26
AU4967185A (en) 1986-04-17
AU3914389A (en) 1989-11-16
KR910002691B1 (ko) 1991-05-03
FI93965C (fi) 1995-06-26
AU3914189A (en) 1989-11-16
AU589917B2 (en) 1989-10-26
HK78696A (en) 1996-05-10
DK172037B1 (da) 1997-09-22
ES8702949A1 (es) 1987-01-16
DE3587505D1 (de) 1993-09-09
WO1986002080A1 (en) 1986-04-10
FI862370A0 (fi) 1986-06-03
NO862177L (no) 1986-08-04
NO173557C (no) 1993-12-29
DE3587342T2 (de) 1993-12-02
HK124696A (en) 1996-07-19
NZ213680A (en) 1990-05-28
DK261386A (da) 1986-06-03
FI93965B (fi) 1995-03-15
NO862177D0 (no) 1986-06-02
FI862370A (fi) 1986-06-03

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Legal Events

Date Code Title Description
PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20061120