DE69116034T2 - Immunotestreagenzien und Verfahren zur Bestimmung von Cyclosporin - Google Patents

Immunotestreagenzien und Verfahren zur Bestimmung von Cyclosporin

Info

Publication number
DE69116034T2
DE69116034T2 DE69116034T DE69116034T DE69116034T2 DE 69116034 T2 DE69116034 T2 DE 69116034T2 DE 69116034 T DE69116034 T DE 69116034T DE 69116034 T DE69116034 T DE 69116034T DE 69116034 T2 DE69116034 T2 DE 69116034T2
Authority
DE
Germany
Prior art keywords
cyclosporine
determination
amino acid
disclosed
immunotestreagents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69116034T
Other languages
English (en)
Other versions
DE69116034D1 (de
Inventor
Marjorie A Morrison
Victoria P Meucci
Steven E Lunetta
Mariola B Zajac
Elizabeth A Simpson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE69116034D1 publication Critical patent/DE69116034D1/de
Publication of DE69116034T2 publication Critical patent/DE69116034T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • C07K7/645—Cyclosporins; Related peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69116034T 1990-08-15 1991-08-08 Immunotestreagenzien und Verfahren zur Bestimmung von Cyclosporin Expired - Fee Related DE69116034T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56784290A 1990-08-15 1990-08-15

Publications (2)

Publication Number Publication Date
DE69116034D1 DE69116034D1 (de) 1996-02-15
DE69116034T2 true DE69116034T2 (de) 1996-06-20

Family

ID=24268868

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69116034T Expired - Fee Related DE69116034T2 (de) 1990-08-15 1991-08-08 Immunotestreagenzien und Verfahren zur Bestimmung von Cyclosporin

Country Status (10)

Country Link
US (2) US5489668A (de)
EP (1) EP0473961B1 (de)
JP (1) JP3171460B2 (de)
AT (1) ATE132504T1 (de)
AU (1) AU642035B2 (de)
CA (1) CA2049089C (de)
DE (1) DE69116034T2 (de)
DK (1) DK0473961T3 (de)
ES (1) ES2084069T3 (de)
GR (1) GR3019512T3 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0674178B1 (de) * 1990-11-20 2002-08-28 Dade Behring Marburg GmbH Cyclosporin-Immunoassay
US5352803A (en) * 1992-03-30 1994-10-04 Abbott Laboratories 5(6)-methyl substituted fluorescein derivatives
CA2131727A1 (en) * 1992-03-30 1993-10-14 Diana E. Clarisse Reagents and methods for the detection and quantification of thyroxine in fluid samples
USRE40596E1 (en) * 1993-04-08 2008-12-02 Novartis Ag Rapamycin assay
GB9307491D0 (en) * 1993-04-08 1993-06-02 Sandoz Ltd Organic compounds
US5504091A (en) * 1993-04-23 1996-04-02 American Home Products Corporation Biotin esters of rapamycin
AU686629B2 (en) 1993-04-23 1998-02-12 Wyeth Rapamycin Conjugates and Antibodies
US7279561B1 (en) 1993-04-23 2007-10-09 Wyeth Anti-rapamycin monoclonal antibodies
US5393891A (en) * 1993-06-08 1995-02-28 The Du Pont Merck Pharmaceutical Company Immunoassay reagents and methods for detecting brequinar and analogs
US5650288A (en) * 1995-07-14 1997-07-22 Macfarlane; Gordon D. Immunophilin-bound immunosuppressant assay
US20030220234A1 (en) * 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
JP4261049B2 (ja) 1997-10-08 2009-04-30 アイソテクニカ インコーポレイテッド 重水素化シクロスポリンアナログおよび免疫調節剤としてのそれらの使用
US5990274A (en) 1997-11-25 1999-11-23 Dade Behring Inc. Cyclosporine derivatives and uses thereof
US8569516B2 (en) 2001-09-07 2013-10-29 Elitech Holding B.V. Compounds and methods for fluorescent labeling
US6972339B2 (en) 2001-09-07 2005-12-06 Epoch Biosciences, Inc. Compounds and methods for fluorescent labeling
PL210795B1 (pl) 2001-10-19 2012-03-30 Isotechnika Inc Sposób wytwarzania mieszaniny ISATX247 wzbogaconej w izomer (E), sposób wytwarzania mieszaniny ISATX247 wzbogaconej w izomer (Z), sposób stereoselektywnej syntezy izomeru (E) ISATX247, sposób stereoselektywnej syntezy izomeru (Z) ISATX247 i sposób wytwarzania mieszaniny izomerów ISATX247
KR100444698B1 (ko) * 2001-11-08 2004-08-21 한국과학기술연구원 면역복합체 단일검출시약, 그의 제조방법 및 그를 이용한농약의 검출방법
US8022188B2 (en) * 2006-04-24 2011-09-20 Abbott Laboratories Immunosuppressant binding antibodies and methods of obtaining and using same
US7883855B2 (en) * 2006-07-21 2011-02-08 Abbott Laboratories Immunosuppressant drug extraction reagent for immunoassays
WO2008069917A2 (en) 2006-11-20 2008-06-12 Scynexis, Inc. Novel cyclic peptides
US7914999B2 (en) * 2006-12-29 2011-03-29 Abbott Laboratories Non-denaturing lysis reagent
WO2008082984A2 (en) * 2006-12-29 2008-07-10 Abbott Laboratories Non-denaturing lysis reagent for use with capture-in-solution immunoassay
ES2393135T3 (es) 2006-12-29 2012-12-18 Abbott Laboratories Ensayo mejorado para fármacos inmunosupresores
ES2405364T3 (es) * 2006-12-29 2013-05-30 Abbott Laboratories Ensayo diagnóstico para la detección de una molécula o fármaco en sangre entera
ES2377167T3 (es) 2007-05-24 2012-03-23 Abbott Laboratories Inmunoensayos que muestran reactividad cruzada reducida con metabolitos de analito de fármacos hidrófobos
CA2709272C (en) * 2007-12-19 2015-03-10 Abbott Laboratories Immunosuppressant drug extraction reagent for immunoassays
US20090170218A1 (en) * 2008-01-02 2009-07-02 Dade Behring Inc. Methods for detection of cyclosporin a
CN110320364B (zh) * 2018-03-30 2023-03-31 洛阳普泰生物技术有限公司 一种双抗夹心胶体金检测试剂盒、及其制备方法与应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1023287A (en) * 1972-12-08 1977-12-27 Boehringer Mannheim G.M.B.H. Process for the preparation of carrier-bound proteins
US4117118A (en) * 1976-04-09 1978-09-26 Sandoz Ltd. Organic compounds
DE2819094A1 (de) * 1977-05-10 1978-11-23 Sandoz Ag Cyclosporin-derivate, ihre verwendung und herstellung
US5169773A (en) * 1984-10-04 1992-12-08 Sandoz Ltd. Monoclonal antibodies to cyclosporins
EP0198026B1 (de) * 1984-10-04 1993-08-04 Sandoz Ag Monoklonale antikörper gegen zyklosporine
US4727035A (en) * 1984-11-14 1988-02-23 Mahoney Walter C Immunoassay for cyclosporin
US5124457A (en) * 1986-05-21 1992-06-23 Abbott Laboratories Phencyclidine and phencyclidine metabolites assay, tracers, immunogens and antibodies
US4939264A (en) * 1986-07-14 1990-07-03 Abbott Laboratories Immunoassay for opiate alkaloids and their metabolites; tracers, immunogens and antibodies
EP0283801A3 (de) * 1987-03-27 1990-05-30 Abbott Laboratories Fluoreszenz-Polarisations-Test für Cyclosporin A und Metaboliten und verwandte Immunogene und Antikörper
US5427960A (en) * 1987-03-27 1995-06-27 Abbott Laboratories Fluorescence polarization assay for cyclosporin A and metabolites and related immunogens and antibodies
US5239057A (en) * 1987-03-27 1993-08-24 Abbott Laboratories Fluorescence polarization assay for cyclosporin a and metabolites and related immunogens and antibodies
EP0329184A3 (de) * 1988-02-19 1990-05-23 Neorx Corporation Antimere und antimere Konjugation

Also Published As

Publication number Publication date
EP0473961B1 (de) 1996-01-03
JP3171460B2 (ja) 2001-05-28
DK0473961T3 (da) 1996-07-01
CA2049089C (en) 2002-09-03
AU642035B2 (en) 1993-10-07
ES2084069T3 (es) 1996-05-01
US5750413A (en) 1998-05-12
ATE132504T1 (de) 1996-01-15
AU8247191A (en) 1992-02-20
CA2049089A1 (en) 1992-02-16
GR3019512T3 (en) 1996-07-31
EP0473961A3 (en) 1993-04-14
EP0473961A2 (de) 1992-03-11
DE69116034D1 (de) 1996-02-15
JPH04253999A (ja) 1992-09-09
US5489668A (en) 1996-02-06

Similar Documents

Publication Publication Date Title
DE69116034T2 (de) Immunotestreagenzien und Verfahren zur Bestimmung von Cyclosporin
DK261386A (da) Monoklonale antistoffer
ES2091301T3 (es) Inmunoensayo de ciclosporina.
EP0284587A3 (de) Synthetische Peptid-Antigene für den Nachweis von HIV-1-Infektionen
Elphick et al. Isolation of the neuropeptide SALMFamide-1 from starfish using a new antiserum
ES2123677T3 (es) Ligadores de maleinimida trifuncionales homobidentados y su uso en conjugados inmunologicamente activos.
EP0869177A3 (de) Menschliche Typ-A und Typ-B Blutplättchen abstammenden Wachstumfaktor Rezeptoren
WO1995020764A1 (de) Spezifische bindungssubstanzen für antikörper und deren verwendung für immunoassays oder vakzine
ATE116660T1 (de) Künstliche peptid-zusammensetzungen mit immunoreaktiven antikörpern von htlv-1.
PT85881A (de) Analoga von gonadoliberin mit verbesserter loslichkeit verfahren zu deren herstellung diese enthaltende mittel und ihre verwendung
IE893110L (en) Peptides having t cell suppressor activity
IE872802L (en) New pep£tides and applications thereof
DE69111149D1 (de) Enzymatisches Verfahren zur Bestimmung von beta-Laktam-Antibiotika.
SLAUGHTER et al. BBA 31240

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee