HK61486A - 4-aroylimidazol-2-ones - Google Patents

4-aroylimidazol-2-ones

Info

Publication number
HK61486A
HK61486A HK614/86A HK61486A HK61486A HK 61486 A HK61486 A HK 61486A HK 614/86 A HK614/86 A HK 614/86A HK 61486 A HK61486 A HK 61486A HK 61486 A HK61486 A HK 61486A
Authority
HK
Hong Kong
Prior art keywords
alkyl
phenyl
hydrogen
alkoxy
hydroxy
Prior art date
Application number
HK614/86A
Other languages
English (en)
Inventor
C. Dage Richard
Martin Grisar J.
A. Schnettler Richard
Original Assignee
Richardson-Merrell Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26727558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK61486(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Richardson-Merrell Inc. filed Critical Richardson-Merrell Inc.
Publication of HK61486A publication Critical patent/HK61486A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK614/86A 1979-06-18 1986-08-21 4-aroylimidazol-2-ones HK61486A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4980879A 1979-06-18 1979-06-18
US11920780A 1980-02-07 1980-02-07

Publications (1)

Publication Number Publication Date
HK61486A true HK61486A (en) 1986-08-29

Family

ID=26727558

Family Applications (1)

Application Number Title Priority Date Filing Date
HK614/86A HK61486A (en) 1979-06-18 1986-08-21 4-aroylimidazol-2-ones

Country Status (20)

Country Link
AT (1) AT375349B (cg-RX-API-DMAC7.html)
AU (1) AU532783B2 (cg-RX-API-DMAC7.html)
CA (1) CA1132554A (cg-RX-API-DMAC7.html)
CH (1) CH646155A5 (cg-RX-API-DMAC7.html)
DE (1) DE3021792A1 (cg-RX-API-DMAC7.html)
DK (1) DK160269C (cg-RX-API-DMAC7.html)
ES (1) ES8105299A1 (cg-RX-API-DMAC7.html)
FR (1) FR2459233A1 (cg-RX-API-DMAC7.html)
GB (1) GB2055364B (cg-RX-API-DMAC7.html)
HK (1) HK61486A (cg-RX-API-DMAC7.html)
HU (1) HU186736B (cg-RX-API-DMAC7.html)
IE (1) IE50646B1 (cg-RX-API-DMAC7.html)
IL (1) IL60243A (cg-RX-API-DMAC7.html)
IT (1) IT1143922B (cg-RX-API-DMAC7.html)
MY (1) MY8600709A (cg-RX-API-DMAC7.html)
NL (2) NL193752C (cg-RX-API-DMAC7.html)
NO (1) NO152841C (cg-RX-API-DMAC7.html)
NZ (1) NZ193935A (cg-RX-API-DMAC7.html)
PH (1) PH18683A (cg-RX-API-DMAC7.html)
SE (2) SE447107B (cg-RX-API-DMAC7.html)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH18106A (en) * 1981-02-18 1985-03-21 Merrell Dow Pharma Novel-4-aroylimidazol-2-ones
US4405628A (en) * 1981-03-05 1983-09-20 Merrell Dow Pharmaceuticals Inc. 4-Pyridylimidazolones and method of use
US4371737A (en) * 1981-05-04 1983-02-01 Merrell Dow Pharmaceuticals Inc. 5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4329471A (en) * 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4526981A (en) * 1981-05-04 1985-07-02 Merrell Dow Pharmaceuticals Inc. [1,2-Dihydro-4(5)-acyl-2-oxo-2H-imidazol-4(5)-yl] methyl nitrates
ZA822990B (en) * 1981-05-04 1983-03-30 Merrell Dow Pharma 4-oxymethyl-5-acyl-1,3-dihydro-2h-imidazol-2-ones
US4329470A (en) 1981-05-04 1982-05-11 Merrell Dow Pharmaceuticals Inc. 5-(4-Phenyl 1-piperidinyl)methyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives
US4381393A (en) * 1981-05-04 1983-04-26 Merrell Dow Pharmaceuticals Inc. 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones
US4367236A (en) * 1981-11-04 1983-01-04 Merrell Dow Pharmaceuticals Inc. Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US4410540A (en) * 1981-11-04 1983-10-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic 4-aroylimidazolidin-2-ones
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
JP2007530566A (ja) * 2004-03-22 2007-11-01 ミオゲン インコーポレイティッド （ｒ）−エノキシモンスルホキシドおよびｐｄｅ−ｉｉｉ媒介疾患の治療におけるその使用
JP2007530563A (ja) * 2004-03-22 2007-11-01 ミオゲン インコーポレイティッド （ｓ）−エノキシモンスルホキシドおよびｐｄｅ−ｉｉｉ媒介疾患の治療におけるその使用
TWI435729B (zh) 2005-11-09 2014-05-01 Combinatorx Inc 治療病症之方法，組合物及套組
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2930674A1 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011528375A (ja) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
KR102034748B1 (ko) 2011-03-01 2019-10-21 시너지 파마슈티컬즈 인코포레이티드 구아닐레이트 사이클라제 c 작용제의 제조 방법
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
EP3718557A3 (en) 2013-02-25 2020-10-21 Bausch Health Ireland Limited Guanylate cyclase receptor agonist sp-333 for use in colonic cleansing
US9708367B2 (en) 2013-03-15 2017-07-18 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
EP4424697A3 (en) 2013-06-05 2024-12-25 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase c, method of making and using same
CA2920856A1 (en) 2013-08-09 2015-02-12 Ardelyx, Inc. Ph modulating compounds for inhibiting gastrointestinal phosphate uptake
CN114340631A (zh) 2019-05-21 2022-04-12 阿德利克斯股份有限公司 用于降低患者的血清磷酸盐的组合
CN114539157B (zh) * 2022-03-03 2023-12-22 曲靖师范学院 一种碘促进氧化法制备4-碘代n-芳基吡唑类化合物的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2441933A (en) * 1945-07-30 1948-05-18 Hoffmann La Roche Substituted imidazolones and process of making them

Also Published As

Publication number Publication date
ATA314280A (de) 1983-12-15
DE3021792A1 (de) 1981-01-22
CA1132554A (en) 1982-09-28
DE3021792C2 (cg-RX-API-DMAC7.html) 1989-08-10
SE8004253L (sv) 1980-12-19
PH18683A (en) 1985-08-29
SE447107B (sv) 1986-10-27
NO152841C (no) 1985-11-27
IT8048997A0 (it) 1980-06-17
DK160269C (da) 1991-07-22
NL8003498A (nl) 1980-12-22
IL60243A (en) 1987-01-30
AU532783B2 (en) 1983-10-13
AT375349B (de) 1984-07-25
NL300015I1 (nl) 2000-11-01
FR2459233B1 (cg-RX-API-DMAC7.html) 1983-09-23
NO801796L (no) 1980-12-19
HU186736B (en) 1985-09-30
CH646155A5 (de) 1984-11-15
NZ193935A (en) 1985-05-31
DK259080A (da) 1980-12-19
IE801162L (en) 1980-12-18
MY8600709A (en) 1986-12-31
ES492255A0 (es) 1981-06-01
IE50646B1 (en) 1986-06-11
IL60243A0 (en) 1980-09-16
NL193752C (nl) 2000-09-04
FR2459233A1 (fr) 1981-01-09
SE8501452D0 (sv) 1985-03-25
GB2055364A (en) 1981-03-04
ES8105299A1 (es) 1981-06-01
SE464559B (sv) 1991-05-13
DK160269B (da) 1991-02-18
NL193752B (nl) 2000-05-01
IT1143922B (it) 1986-10-29
NO152841B (no) 1985-08-19
GB2055364B (en) 1983-06-08
SE8501452L (sv) 1985-03-25
NL300015I2 (nl) 2000-10-02
AU5911880A (en) 1981-01-08

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Legal Events

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PE Patent expired