HK1258050A1 - 用於治療劑緩釋的胃駐留系統及其使用方法 - Google Patents

用於治療劑緩釋的胃駐留系統及其使用方法

Info

Publication number
HK1258050A1
HK1258050A1 HK19100427.2A HK19100427A HK1258050A1 HK 1258050 A1 HK1258050 A1 HK 1258050A1 HK 19100427 A HK19100427 A HK 19100427A HK 1258050 A1 HK1258050 A1 HK 1258050A1
Authority
HK
Hong Kong
Prior art keywords
methods
therapeutic agents
sustained release
gastric residence
residence systems
Prior art date
Application number
HK19100427.2A
Other languages
English (en)
Inventor
Rosemary Kanasty
Andrew Bellinger
Colin Gardner
Tyler Grant
Saumya Singh
Original Assignee
Lyndra Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lyndra Inc filed Critical Lyndra Inc
Publication of HK1258050A1 publication Critical patent/HK1258050A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK19100427.2A 2015-10-23 2019-01-11 用於治療劑緩釋的胃駐留系統及其使用方法 HK1258050A1 (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562245797P 2015-10-23 2015-10-23
US201562245789P 2015-10-23 2015-10-23
US201562264799P 2015-12-08 2015-12-08
US201562264806P 2015-12-08 2015-12-08
US201562264795P 2015-12-08 2015-12-08
US201662402947P 2016-09-30 2016-09-30
PCT/US2016/058309 WO2017070612A1 (en) 2015-10-23 2016-10-21 Gastric residence systems for sustained release of therapeutic agents and methods of use thereof

Publications (1)

Publication Number Publication Date
HK1258050A1 true HK1258050A1 (zh) 2019-11-01

Family

ID=58558169

Family Applications (1)

Application Number Title Priority Date Filing Date
HK19100427.2A HK1258050A1 (zh) 2015-10-23 2019-01-11 用於治療劑緩釋的胃駐留系統及其使用方法

Country Status (8)

Country Link
US (1) US11576859B2 (zh)
EP (1) EP3364946A4 (zh)
JP (2) JP7085473B2 (zh)
CN (1) CN108472249A (zh)
AU (1) AU2016342374B2 (zh)
CA (1) CA3002916A1 (zh)
HK (1) HK1258050A1 (zh)
WO (1) WO2017070612A1 (zh)

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US20170266112A1 (en) 2014-06-11 2017-09-21 Massachusetts Institute Of Technology Residence structures and related methods
NZ727659A (en) 2014-06-11 2021-12-24 Massachusetts Inst Technology Residence structures and related methods
CN108472249A (zh) 2015-10-23 2018-08-31 林德拉有限公司 用于治疗剂缓释的胃驻留系统及其使用方法
CA3025650A1 (en) * 2016-05-27 2017-11-30 Lyndra, Inc. Materials architecture for gastric residence systems
CN110022861A (zh) 2016-09-30 2019-07-16 林德拉有限公司 用于金刚烷类药物缓释的胃驻留系统
US11541015B2 (en) 2017-05-17 2023-01-03 Massachusetts Institute Of Technology Self-righting systems, methods, and related components
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CN110996906A (zh) * 2017-06-09 2020-04-10 林德拉有限公司 具有调节释放速度的膜的胃驻留系统
KR102046395B1 (ko) * 2017-12-12 2019-11-19 동아에스티 주식회사 베포타스틴 또는 이의 약제학적으로 허용 가능한 염을 포함하는 서방성 제제
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IL308210A (en) * 2021-05-05 2024-01-01 Lyndra Therapeutics Inc Gastric retention systems including buprenorphine and naloxone
EP4333824A1 (en) * 2021-05-05 2024-03-13 Lyndra Therapeutics, Inc. Gastric residence systems comprising methadone
AU2022320730A1 (en) 2021-07-30 2024-03-14 Evecxia Therapeutics, Inc. 5-hydroxytryptophan gastroretentive dosage forms
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WO2023141524A2 (en) * 2022-01-19 2023-07-27 Lyndra Therapeutics, Inc. Dosage forms for gastric retention

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