HK1255500A1 - 氧固醇及其使用方法 - Google Patents

氧固醇及其使用方法 Download PDF

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Publication number
HK1255500A1
HK1255500A1 HK18114684.2A HK18114684A HK1255500A1 HK 1255500 A1 HK1255500 A1 HK 1255500A1 HK 18114684 A HK18114684 A HK 18114684A HK 1255500 A1 HK1255500 A1 HK 1255500A1
Authority
HK
Hong Kong
Prior art keywords
sup
oxysterols
methods
compounds
prevention
Prior art date
Application number
HK18114684.2A
Other languages
English (en)
Chinese (zh)
Inventor
Francesco G. Salituro
Albert Jean Robichaud
Gabriel Martinez Botella
Original Assignee
Sage Therapeutics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sage Therapeutics, Inc. filed Critical Sage Therapeutics, Inc.
Publication of HK1255500A1 publication Critical patent/HK1255500A1/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK18114684.2A 2015-07-06 2016-07-06 氧固醇及其使用方法 HK1255500A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562189065P 2015-07-06 2015-07-06
US201562189065P 2015-07-06
PCT/US2016/041160 WO2017007832A1 (en) 2015-07-06 2016-07-06 Oxysterols and methods of use thereof

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
HK42024094996.6A Division HK40107350A (en) 2015-07-06 2018-11-16 Oxysterols and methods of use thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
HK42024094996.6A Addition HK40107350A (en) 2015-07-06 2018-11-16 Oxysterols and methods of use thereof

Publications (1)

Publication Number Publication Date
HK1255500A1 true HK1255500A1 (zh) 2019-08-16

Family

ID=57686058

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18114684.2A HK1255500A1 (zh) 2015-07-06 2016-07-06 氧固醇及其使用方法

Country Status (8)

Country Link
US (4) US10696712B2 (enExample)
EP (2) EP3319610A4 (enExample)
JP (3) JP6882996B2 (enExample)
AU (2) AU2016289965B2 (enExample)
CA (1) CA2991311C (enExample)
HK (1) HK1255500A1 (enExample)
MA (1) MA42409A (enExample)
WO (1) WO2017007832A1 (enExample)

Families Citing this family (17)

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CN107936076B (zh) 2011-09-08 2021-10-15 萨奇治疗股份有限公司 神经活性类固醇、组合物、及其用途
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EP3828194B1 (en) 2015-07-06 2025-04-16 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
PL3319612T3 (pl) * 2015-07-06 2021-12-20 Sage Therapeutics, Inc. Oksysterole i sposoby ich stosowania
HK1255500A1 (zh) 2015-07-06 2019-08-16 Sage Therapeutics, Inc. 氧固醇及其使用方法
US20190330259A1 (en) 2016-04-01 2019-10-31 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
US10752653B2 (en) 2016-05-06 2020-08-25 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
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CN121085986A (zh) 2016-09-30 2025-12-09 萨奇治疗股份有限公司 C7取代的氧固醇及其作为nmda调节剂的方法
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Also Published As

Publication number Publication date
EP3319610A1 (en) 2018-05-16
JP2021063118A (ja) 2021-04-22
AU2021218227A1 (en) 2021-09-09
JP7410062B2 (ja) 2024-01-09
US20230047157A1 (en) 2023-02-16
AU2016289965A1 (en) 2018-01-18
US20210101925A1 (en) 2021-04-08
NZ738582A (en) 2024-10-25
AU2016289965B2 (en) 2021-09-09
JP2018519329A (ja) 2018-07-19
US20250154192A1 (en) 2025-05-15
JP6882996B2 (ja) 2021-06-02
WO2017007832A1 (en) 2017-01-12
JP2022130668A (ja) 2022-09-06
JP7478190B2 (ja) 2024-05-02
AU2021218227B2 (en) 2023-08-03
CA2991311A1 (en) 2017-01-12
US10696712B2 (en) 2020-06-30
EP4316591A3 (en) 2024-04-24
EP4316591A2 (en) 2024-02-07
EP3319610A4 (en) 2019-03-06
CA2991311C (en) 2025-05-06
MA42409A (fr) 2018-05-16
US20180201643A1 (en) 2018-07-19

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