HK1248548A1 - 用於將治療劑和診斷劑遞送到細胞中的方法、組合物和系統 - Google Patents

用於將治療劑和診斷劑遞送到細胞中的方法、組合物和系統

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Publication number
HK1248548A1
HK1248548A1 HK18108250.8A HK18108250A HK1248548A1 HK 1248548 A1 HK1248548 A1 HK 1248548A1 HK 18108250 A HK18108250 A HK 18108250A HK 1248548 A1 HK1248548 A1 HK 1248548A1
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Hong Kong
Prior art keywords
compositions
cells
systems
methods
diagnostic agents
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HK18108250.8A
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English (en)
Inventor
M‧G‧普瑞夫
M‧E‧小豪斯頓
P‧哈維
S‧D‧莫納漢
Original Assignee
菲澤爾克斯公司
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Application filed by 菲澤爾克斯公司 filed Critical 菲澤爾克斯公司
Publication of HK1248548A1 publication Critical patent/HK1248548A1/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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    • A61K48/0041—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid the non-active part being polymeric
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    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
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HK18108250.8A 2015-01-21 2018-06-27 用於將治療劑和診斷劑遞送到細胞中的方法、組合物和系統 HK1248548A1 (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201562106024P 2015-01-21 2015-01-21
US201562173847P 2015-06-10 2015-06-10
US201562233568P 2015-09-28 2015-09-28
PCT/US2016/014232 WO2016118697A1 (en) 2015-01-21 2016-01-21 Methods, compositions, and systems for delivering therapeutic and diagnostic agents into cells

Publications (1)

Publication Number Publication Date
HK1248548A1 true HK1248548A1 (zh) 2018-10-19

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HK18108250.8A HK1248548A1 (zh) 2015-01-21 2018-06-27 用於將治療劑和診斷劑遞送到細胞中的方法、組合物和系統

Country Status (8)

Country Link
US (2) US11219634B2 (zh)
EP (1) EP3247328A1 (zh)
JP (2) JP2018509387A (zh)
CN (2) CN107530436B (zh)
AU (1) AU2016209295B2 (zh)
CA (1) CA2974503A1 (zh)
HK (1) HK1248548A1 (zh)
WO (1) WO2016118697A1 (zh)

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