US9266960B2
(en)
*
|
2011-04-08 |
2016-02-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-epidermal growth factor receptor variant III chimeric antigen receptors and use of same for the treatment of cancer
|
CA2868121C
(en)
|
2012-03-23 |
2021-06-01 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Anti-mesothelin chimeric antigen receptors
|
WO2014039044A1
(en)
|
2012-09-06 |
2014-03-13 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of producing t memory stem cell populations
|
AU2013204922B2
(en)
|
2012-12-20 |
2015-05-14 |
Celgene Corporation |
Chimeric antigen receptors
|
CN111139256A
(zh)
*
|
2013-02-20 |
2020-05-12 |
诺华股份有限公司 |
使用人源化抗EGFRvIII嵌合抗原受体治疗癌症
|
UY35340A
(es)
|
2013-02-20 |
2014-09-30 |
Novartis Ag |
Marcaje efectivo de leucemia humana usando células diseñadas con un receptor quimérico de antígeno anti-cd123
|
US10238690B2
(en)
|
2013-03-15 |
2019-03-26 |
Celgene Corporation |
Modified T lymphocytes comprising an inducible caspase and methods of apoptosis
|
UY35468A
(es)
|
2013-03-16 |
2014-10-31 |
Novartis Ag |
Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
|
US10208125B2
(en)
|
2013-07-15 |
2019-02-19 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Anti-mucin 1 binding agents and uses thereof
|
WO2015090230A1
(en)
|
2013-12-19 |
2015-06-25 |
Novartis Ag |
Human mesothelin chimeric antigen receptors and uses thereof
|
US11028143B2
(en)
|
2014-01-21 |
2021-06-08 |
Novartis Ag |
Enhanced antigen presenting ability of RNA CAR T cells by co-introduction of costimulatory molecules
|
EP4215603A1
(en)
*
|
2014-02-04 |
2023-07-26 |
Kite Pharma, Inc. |
Methods for producing autologous t cells useful to treat b cell malignancies and other cancers and compositions thereof
|
EP3593812A3
(en)
|
2014-03-15 |
2020-05-27 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor
|
IL293603B2
(en)
|
2014-04-07 |
2024-03-01 |
Novartis Ag |
Cancer treatment using chimeric antigen receptor (CAR) against CD19
|
KR20200000495A
(ko)
*
|
2014-05-14 |
2020-01-02 |
카르스젠 테라퓨틱스 리미티드 |
키메라 항원 수용체 단백질을 코딩하는 핵산 및 키메라 항원 수용체 단백질을 발현하는 t 림프구
|
WO2015187528A1
(en)
*
|
2014-06-02 |
2015-12-10 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Chimeric antigen receptors targeting cd-19
|
TWI718992B
(zh)
|
2014-07-21 |
2021-02-21 |
瑞士商諾華公司 |
使用cll-1嵌合抗原受體治療癌症
|
US9777061B2
(en)
|
2014-07-21 |
2017-10-03 |
Novartis Ag |
Treatment of cancer using a CD33 chimeric antigen receptor
|
US10174095B2
(en)
|
2014-07-21 |
2019-01-08 |
Novartis Ag |
Nucleic acid encoding a humanized anti-BCMA chimeric antigen receptor
|
JP2017528433A
(ja)
|
2014-07-21 |
2017-09-28 |
ノバルティス アーゲー |
低い免疫増強用量のmTOR阻害剤とCARの組み合わせ
|
RU2017102769A
(ru)
*
|
2014-07-29 |
2018-08-28 |
Пфайзер Инк. |
EGFRvIII СПЕЦИФИЧЕСКИЕ ХИМЕРНЫЕ АНТИГЕННЫЕ РЕЦЕПТОРЫ ДЛЯ ИММУНОТЕРАПИИ РАКА
|
AU2015301460B2
(en)
|
2014-08-14 |
2021-04-08 |
Novartis Ag |
Treatment of cancer using GFR alpha-4 chimeric antigen receptor
|
CA2961636A1
(en)
|
2014-09-17 |
2016-03-24 |
Boris ENGELS |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
CA2963935A1
(en)
|
2014-10-08 |
2016-04-14 |
Novartis Ag |
Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
|
PL3597742T3
(pl)
|
2014-10-09 |
2022-11-14 |
Yamaguchi University |
Wektor ekspresyjny CAR oraz komórki T wykazujące ekspresję CAR
|
US20180334490A1
(en)
|
2014-12-03 |
2018-11-22 |
Qilong H. Wu |
Methods for b cell preconditioning in car therapy
|
JP6724009B2
(ja)
*
|
2014-12-08 |
2020-07-15 |
アメリカ合衆国 |
抗cd70キメラ抗原受容体
|
US10273300B2
(en)
|
2014-12-29 |
2019-04-30 |
The Trustees Of The University Of Pennsylvania |
Methods of making chimeric antigen receptor-expressing cells
|
BR112017015453A2
(pt)
|
2015-01-26 |
2018-01-23 |
Cellectis |
células imunes modificadas knockout para receptor de células t, dotadas de receptores quiméricos de antígeno, de ligação a cd123 para o tratamento de linfoma mieloide agudo recorrente/refratário ou neoplasia blástica de células dendríticas plasmacitoides
|
WO2016126608A1
(en)
|
2015-02-02 |
2016-08-11 |
Novartis Ag |
Car-expressing cells against multiple tumor antigens and uses thereof
|
AU2016219785B2
(en)
|
2015-02-20 |
2021-10-28 |
Ohio State Innovation Foundation |
Bivalent antibody directed against NKG2D and tumor associated antigens
|
EP3262063B1
(en)
*
|
2015-02-26 |
2021-09-22 |
Var2 Pharmaceuticals ApS |
Immunotherapeutic targeting of placental-like chondroitin sulfate using chimeric antigen receptors (cars) and immunotherapeutic targeting of cancer using cars with split-protein binding systems
|
CN106146666B
(zh)
*
|
2015-03-26 |
2019-09-06 |
科济生物医药(上海)有限公司 |
靶向cldn6的免疫效应细胞及其制备方法和应用
|
CN108367057B
(zh)
*
|
2015-04-06 |
2022-11-22 |
赛通免疫股份有限公司 |
用于胶质母细胞瘤的egfr导向的car疗法
|
WO2016164580A1
(en)
|
2015-04-07 |
2016-10-13 |
Novartis Ag |
Combination of chimeric antigen receptor therapy and amino pyrimidine derivatives
|
RU2021121771A
(ru)
|
2015-04-08 |
2022-01-12 |
Новартис Аг |
Cd20 терапия, cd22 терапия и комбинированная терапия клетками, экспрессирующими химерный антигенный рецептор (car) к cd19
|
WO2016168595A1
(en)
|
2015-04-17 |
2016-10-20 |
Barrett David Maxwell |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
US10738290B2
(en)
|
2015-04-21 |
2020-08-11 |
Novartis Ag |
RNA-guided gene editing system and uses thereof
|
WO2016172583A1
(en)
|
2015-04-23 |
2016-10-27 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
PL3298033T5
(pl)
|
2015-05-18 |
2023-10-30 |
TCR2 Therapeutics Inc. |
Kompozycje i zastosowania medyczne do reprogramowania TCR z zastosowaniem białek fuzyjnych
|
ES2889906T3
(es)
|
2015-05-21 |
2022-01-14 |
Harpoon Therapeutics Inc |
Proteínas de unión triespecíficas y usos médicos
|
EP4349854A2
(en)
|
2015-06-19 |
2024-04-10 |
Kobold, Sebastian |
Pd1-cd28 fusion proteins and their use in medicine
|
AU2016297014B2
(en)
|
2015-07-21 |
2021-06-17 |
Novartis Ag |
Methods for improving the efficacy and expansion of immune cells
|
EP3331913A1
(en)
|
2015-08-07 |
2018-06-13 |
Novartis AG |
Treatment of cancer using chimeric cd3 receptor proteins
|
JP2018522907A
(ja)
|
2015-08-11 |
2018-08-16 |
セレクティスCellectis |
Cd38抗原を標的とするためおよびcd38遺伝子を不活化するために操作された、免疫療法用の細胞
|
WO2017035251A1
(en)
|
2015-08-25 |
2017-03-02 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
T cells modified to overexpress c-myb
|
US11747346B2
(en)
|
2015-09-03 |
2023-09-05 |
Novartis Ag |
Biomarkers predictive of cytokine release syndrome
|
US10221249B2
(en)
|
2015-09-10 |
2019-03-05 |
Affigen, Llc |
Method of making patient specific anti-idiotype antibodies
|
DK3362569T3
(da)
|
2015-10-16 |
2021-10-18 |
Univ Muenchen Ludwig Maximilians |
Cxcr6-transducerede t-celler til målrettet tumorterapi
|
WO2017070042A1
(en)
|
2015-10-20 |
2017-04-27 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of producing t cell populations using akt inhibitors
|
UY36961A
(es)
*
|
2015-10-23 |
2017-05-31 |
Sorrento Therapeutics Inc |
Receptores celulares universales programables y métodos para usar los mismos
|
US20180362975A1
(en)
|
2015-12-04 |
2018-12-20 |
Novartis Ag |
Compositions and methods for immunooncology
|
EP3397756B1
(en)
|
2015-12-30 |
2023-03-08 |
Novartis AG |
Immune effector cell therapies with enhanced efficacy
|
CN106967684A
(zh)
*
|
2016-01-13 |
2017-07-21 |
北京马力喏生物科技有限公司 |
共表达抗EGFRvIII嵌合抗原受体和无功能EGFR受体的转基因淋巴细胞及其用途
|
CN106967681B
(zh)
*
|
2016-01-13 |
2020-06-05 |
北京马力喏生物科技有限公司 |
治疗脑胶质母细胞瘤的治疗组合物
|
CN108699124A
(zh)
*
|
2016-01-21 |
2018-10-23 |
辉瑞大药厂 |
靶向表皮生长因子受体变体iii的嵌合抗原受体
|
US10221242B2
(en)
|
2016-01-21 |
2019-03-05 |
Pfizer Inc. |
Antibodies specific for epidermal growth factor receptor variant III and their uses
|
WO2017139199A1
(en)
|
2016-02-10 |
2017-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Inducible arginase
|
BR112018067679A2
(pt)
|
2016-03-04 |
2019-01-15 |
Novartis Ag |
células que expressam múltiplas moléculas do receptor de antígeno quimérico (car) e seu uso
|
HRP20230457T1
(hr)
|
2016-04-15 |
2023-07-21 |
Novartis Ag |
Pripravci i postupci za selektivnu ekspresiju kimernih antigenskih receptora
|
US11623958B2
(en)
|
2016-05-20 |
2023-04-11 |
Harpoon Therapeutics, Inc. |
Single chain variable fragment CD3 binding proteins
|
WO2017201488A1
(en)
|
2016-05-20 |
2017-11-23 |
Harpoon Therapeutics, Inc. |
Single domain serum albumin binding protein
|
EP3464375A2
(en)
|
2016-06-02 |
2019-04-10 |
Novartis AG |
Therapeutic regimens for chimeric antigen receptor (car)- expressing cells
|
BR112018077375A2
(pt)
|
2016-06-30 |
2019-10-01 |
F. Hoffmann-La Roche Ag |
kits, moléculas de anticorpo biespecífico trivalente, composição farmacêutica, vetor de expressão, célula hospedeira e método para a produção de uma molécula de anticorpo biespecífico trivalente
|
AU2017295886C1
(en)
|
2016-07-15 |
2024-01-25 |
Novartis Ag |
Treatment and prevention of cytokine release syndrome using a chimeric antigen receptor in combination with a kinase inhibitor
|
US20190151365A1
(en)
|
2016-07-28 |
2019-05-23 |
Novartis Ag |
Combination therapies of chimeric antigen receptors and pd-1 inhibitors
|
US20190161542A1
(en)
|
2016-08-01 |
2019-05-30 |
Novartis Ag |
Treatment of cancer using a chimeric antigen receptor in combination with an inhibitor of a pro-m2 macrophage molecule
|
JP7109789B2
(ja)
|
2016-08-02 |
2022-08-01 |
ティーシーアール2 セラピューティクス インク. |
融合タンパク質を使用したtcrの再プログラム化のための組成物及び方法
|
EP3516045A1
(en)
|
2016-09-23 |
2019-07-31 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Methods of preparing an isolated population of dendritic cells and methods of treating cancer using same
|
WO2018067992A1
(en)
|
2016-10-07 |
2018-04-12 |
Novartis Ag |
Chimeric antigen receptors for the treatment of cancer
|
IL292551B2
(en)
|
2016-10-07 |
2023-10-01 |
Tcr2 Therapeutics Inc |
Preparations and methods for reprogramming T-cell receptors using fusion proteins
|
EP4092049A1
(en)
|
2016-10-20 |
2022-11-23 |
Celgene Corporation |
Cereblon-based heterodimerizable chimeric antigen receptors
|
US11851491B2
(en)
|
2016-11-22 |
2023-12-26 |
TCR2 Therapeutics Inc. |
Compositions and methods for TCR reprogramming using fusion proteins
|
CA3044659A1
(en)
|
2016-11-23 |
2018-05-31 |
Harpoon Therapeutics, Inc. |
Prostate specific membrane antigen binding protein
|
BR112019010602A2
(pt)
|
2016-11-23 |
2019-12-17 |
Harpoon Therapeutics Inc |
proteínas trispecíficas para psma e métodos de uso
|
WO2018111981A1
(en)
|
2016-12-13 |
2018-06-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of preparing an isolated or purified population of thymic emigrant cells and methods of treatment using same
|
WO2018111340A1
(en)
|
2016-12-16 |
2018-06-21 |
Novartis Ag |
Methods for determining potency and proliferative function of chimeric antigen receptor (car)-t cells
|
CN110234343A
(zh)
|
2016-12-21 |
2019-09-13 |
T细胞受体治疗公司 |
用于治疗癌症的经工程改造t细胞
|
BR112019012950A2
(pt)
|
2016-12-23 |
2019-11-26 |
Macrogenics Inc |
molécula de ligação a adam9, composição farmacêutica, uso da molécula de ligação a adam9 e método para tratar uma doença ou condição associada ou caracterizada pela expressão de adam9 em um indivíduo
|
WO2018127585A1
(en)
|
2017-01-06 |
2018-07-12 |
Txcell |
Monospecific regulatory t cell population with cytotoxicity for b cells
|
EP3346001A1
(en)
|
2017-01-06 |
2018-07-11 |
TXCell |
Monospecific regulatory t cell population with cytotoxicity for b cells
|
EP3568474A1
(en)
*
|
2017-01-10 |
2019-11-20 |
Intrexon Corporation |
Modulating expression of polypeptides via new gene switch expression systems
|
GB201700621D0
(en)
|
2017-01-13 |
2017-03-01 |
Guest Ryan Dominic |
Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue
|
CN106636003B
(zh)
*
|
2017-01-24 |
2019-07-12 |
深圳普瑞金生物药业有限公司 |
一种全人源化EGFRvIII嵌合抗原受体T细胞及其制备方法
|
EP4043485A1
(en)
|
2017-01-26 |
2022-08-17 |
Novartis AG |
Cd28 compositions and methods for chimeric antigen receptor therapy
|
EP3577134A1
(en)
|
2017-01-31 |
2019-12-11 |
Novartis AG |
Treatment of cancer using chimeric t cell receptor proteins having multiple specificities
|
US11649288B2
(en)
|
2017-02-07 |
2023-05-16 |
Seattle Children's Hospital |
Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents
|
WO2018160622A1
(en)
|
2017-02-28 |
2018-09-07 |
Endocyte, Inc. |
Compositions and methods for car t cell therapy
|
EP3589662A4
(en)
|
2017-02-28 |
2020-12-30 |
Harpoon Therapeutics, Inc. |
INDUCTIBLE MONOVALENT ANTIGBINDING PROTEIN
|
WO2018160731A1
(en)
|
2017-02-28 |
2018-09-07 |
Novartis Ag |
Shp inhibitor compositions and uses for chimeric antigen receptor therapy
|
CA3054621A1
(en)
|
2017-03-22 |
2018-09-27 |
Novartis Ag |
Compositions and methods for immunooncology
|
WO2018183842A1
(en)
|
2017-03-31 |
2018-10-04 |
The Board Of Trustees Of The Leland Standford Junior University |
Methods of treating t cell exhaustion by inhibiting or modulating t cell receptor signaling
|
CA3059444A1
(en)
*
|
2017-04-14 |
2018-10-18 |
The General Hospital Corporation |
Chimeric antigen receptor t cells targeting the tumor microenvironment
|
KR20190142775A
(ko)
|
2017-04-19 |
2019-12-27 |
보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 |
조작된 항원 수용체를 발현하는 면역 세포
|
EP3615055A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
JP7090347B2
(ja)
|
2017-05-12 |
2022-06-24 |
ハープーン セラピューティクス,インク. |
メソテリン結合タンパク質
|
CA3063362A1
(en)
|
2017-05-12 |
2018-11-15 |
Harpoon Therapeutics, Inc. |
Msln targeting trispecific proteins and methods of use
|
US11883431B2
(en)
|
2017-06-05 |
2024-01-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
T-cells modified to overexpress PHF19
|
WO2018232020A1
(en)
|
2017-06-13 |
2018-12-20 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
CN107338224A
(zh)
*
|
2017-07-04 |
2017-11-10 |
成都克里斯博生物科技有限公司 |
PD‑1敲除EGFRvIIICAR‑T细胞的制备
|
AU2018338423A1
(en)
|
2017-09-20 |
2020-04-09 |
Sangamo Therapeutics France |
Novel anti-HLA-A2 antibodies and uses thereof
|
US20190092818A1
(en)
*
|
2017-09-22 |
2019-03-28 |
Kite Pharma, Inc. |
Chimeric polypeptides and uses thereof
|
WO2019075055A1
(en)
|
2017-10-11 |
2019-04-18 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
METHODS FOR PRODUCING T-CELL POPULATIONS USING P38 MAPK INHIBITORS
|
BR112020007196A2
(pt)
|
2017-10-13 |
2020-12-01 |
Harpoon Therapeutics, Inc. |
proteínas triespecíficas e métodos de uso
|
CR20200195A
(es)
|
2017-10-13 |
2020-08-14 |
Harpoon Therapeutics Inc |
Proteínas de unión a antigenos de maduraciòn de celulas b
|
BR112020007576A2
(pt)
|
2017-10-18 |
2020-09-24 |
Novartis Ag |
composições e métodos para degradação de proteína seletiva
|
CA3078270A1
(en)
|
2017-10-25 |
2019-05-02 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
CN108203732B
(zh)
*
|
2017-10-27 |
2021-07-27 |
上海交通大学医学院附属仁济医院 |
Trim24在胶质瘤诊断中的应用
|
US20210179709A1
(en)
|
2017-10-31 |
2021-06-17 |
Novartis Ag |
Anti-car compositions and methods
|
AU2018369883A1
(en)
|
2017-11-15 |
2020-05-28 |
Novartis Ag |
BCMA-targeting chimeric antigen receptor, CD19-targeting chimeric antigen receptor, and combination therapies
|
WO2019129054A1
(zh)
|
2017-12-27 |
2019-07-04 |
信达生物制药(苏州)有限公司 |
三链抗体、其制备方法及其用途
|
CN112218651A
(zh)
|
2018-01-08 |
2021-01-12 |
诺华公司 |
用于与嵌合抗原受体疗法组合的免疫增强rna
|
US11311576B2
(en)
|
2018-01-22 |
2022-04-26 |
Seattle Children's Hospital |
Methods of use for CAR T cells
|
CA3090249A1
(en)
|
2018-01-31 |
2019-08-08 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
TWI732176B
(zh)
|
2018-02-01 |
2021-07-01 |
大陸商信達生物製藥(蘇州)有限公司 |
全人源的抗b細胞成熟抗原(bcma)單鏈抗體及其應用
|
AU2019218785A1
(en)
|
2018-02-09 |
2020-09-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Tethered interleukin-15 and interleukin-21
|
EP3752203A1
(en)
|
2018-02-13 |
2020-12-23 |
Novartis AG |
Chimeric antigen receptor therapy in combination with il-15r and il15
|
WO2019184909A1
(zh)
|
2018-03-27 |
2019-10-03 |
信达生物制药(苏州)有限公司 |
新型抗体分子、其制备方法及其用途
|
CN110305210B
(zh)
|
2018-03-27 |
2023-02-28 |
信达生物制药(苏州)有限公司 |
新型抗体分子、其制备方法及其用途
|
WO2019197678A1
(en)
|
2018-04-13 |
2019-10-17 |
Sangamo Therapeutics France |
Chimeric antigen receptor specific for interleukin-23 receptor
|
AU2019260656A1
(en)
|
2018-04-24 |
2020-12-10 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of producing T cell populations using hydroxycitric acid and/or a salt thereof
|
EP3784351A1
(en)
|
2018-04-27 |
2021-03-03 |
Novartis AG |
Car t cell therapies with enhanced efficacy
|
EP3788369A1
(en)
|
2018-05-01 |
2021-03-10 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
US20210213063A1
(en)
|
2018-05-25 |
2021-07-15 |
Novartis Ag |
Combination therapy with chimeric antigen receptor (car) therapies
|
CN108707199A
(zh)
*
|
2018-05-29 |
2018-10-26 |
廊坊康宝汇泰生物技术有限公司 |
靶向tem8的嵌合抗原受体t细胞及其应用
|
CN108676098A
(zh)
*
|
2018-05-29 |
2018-10-19 |
段海峰 |
靶向wt1的嵌合抗原受体t细胞及其应用
|
EP3802825A1
(en)
|
2018-06-08 |
2021-04-14 |
Intellia Therapeutics, Inc. |
Compositions and methods for immunooncology
|
EP3806888B1
(en)
|
2018-06-12 |
2024-01-31 |
Obsidian Therapeutics, Inc. |
Pde5 derived regulatory constructs and methods of use in immunotherapy
|
EP3806962A1
(en)
|
2018-06-13 |
2021-04-21 |
Novartis AG |
Bcma chimeric antigen receptors and uses thereof
|
JPWO2020017479A1
(ja)
*
|
2018-07-17 |
2021-08-02 |
ノイルイミューン・バイオテック株式会社 |
抗gpc3一本鎖抗体を含むcar
|
AU2019318135A1
(en)
|
2018-08-10 |
2021-03-04 |
Sangamo Therapeutics France |
New car constructs comprising TNFR2 domains
|
MX2021002225A
(es)
|
2018-08-30 |
2021-07-16 |
Tcr2 Therapeutics Inc |
Composiciones y metodos para la reprogramacion de tcr mediante el uso de proteinas de fusion.
|
US20210171909A1
(en)
|
2018-08-31 |
2021-06-10 |
Novartis Ag |
Methods of making chimeric antigen receptor?expressing cells
|
CA3109959A1
(en)
|
2018-08-31 |
2020-03-05 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
US10815311B2
(en)
|
2018-09-25 |
2020-10-27 |
Harpoon Therapeutics, Inc. |
DLL3 binding proteins and methods of use
|
US20220047633A1
(en)
|
2018-09-28 |
2022-02-17 |
Novartis Ag |
Cd22 chimeric antigen receptor (car) therapies
|
EP3856782A1
(en)
|
2018-09-28 |
2021-08-04 |
Novartis AG |
Cd19 chimeric antigen receptor (car) and cd22 car combination therapies
|
EP3870600A1
(en)
|
2018-10-24 |
2021-09-01 |
Obsidian Therapeutics, Inc. |
Er tunable protein regulation
|
CN111218465A
(zh)
*
|
2018-11-26 |
2020-06-02 |
上海恒润达生生物科技有限公司 |
一种靶向cd22的嵌合抗原受体方法及用途
|
WO2020123691A2
(en)
|
2018-12-12 |
2020-06-18 |
Kite Pharma, Inc |
Chimeric antigen and t cell receptors and methods of use
|
TWI756621B
(zh)
|
2019-01-25 |
2022-03-01 |
大陸商信達生物製藥(蘇州)有限公司 |
新型雙特異性抗體分子以及同時結合pd-l1和lag-3的雙特異性抗體
|
EP3927371A1
(en)
|
2019-02-22 |
2021-12-29 |
Novartis AG |
Combination therapies of egfrviii chimeric antigen receptors and pd-1 inhibitors
|
EP3935151A1
(en)
|
2019-03-08 |
2022-01-12 |
Klinikum der Universität München |
Ccr8 expressing lymphocytes for targeted tumor therapy
|
WO2020191316A1
(en)
|
2019-03-21 |
2020-09-24 |
Novartis Ag |
Car-t cell therapies with enhanced efficacy
|
BR112021019571A2
(pt)
|
2019-04-19 |
2021-12-07 |
Chugai Pharmaceutical Co Ltd |
Receptor quimérico que reconhece o sítio de modificação do anticorpo
|
US20220251152A1
(en)
|
2019-04-24 |
2022-08-11 |
Novartis Ag |
Compositions and methods for selective protein degradation
|
KR20220017430A
(ko)
|
2019-06-05 |
2022-02-11 |
추가이 세이야쿠 가부시키가이샤 |
항체 절단 부위 결합 분자
|
GB201909283D0
(en)
|
2019-06-27 |
2019-08-14 |
Cancer Research Tech Ltd |
Fusion proteins with enzyme activity
|
BR112021026832A2
(pt)
|
2019-07-02 |
2022-05-10 |
Hutchinson Fred Cancer Res |
Vetores ad35 recombinantes e aprimoramentos da terapia gênica relacionada
|
EP3769816A1
(en)
|
2019-07-25 |
2021-01-27 |
Ospedale Pediatrico Bambino Gesù |
Car-cd123 vector and uses thereof
|
WO2021019706A1
(ja)
|
2019-07-31 |
2021-02-04 |
国立大学法人信州大学 |
Car発現免疫細胞を含む細胞集団の製造方法
|
WO2021028359A1
(en)
|
2019-08-09 |
2021-02-18 |
Sangamo Therapeutics France |
Controlled expression of chimeric antigen receptors in t cells
|
WO2021030182A1
(en)
|
2019-08-09 |
2021-02-18 |
A2 Biotherapeutics, Inc. |
Bifunctional single variable domain t cell receptors and uses thereof
|
WO2021035170A1
(en)
|
2019-08-21 |
2021-02-25 |
Precision Biosciences, Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
WO2021046451A1
(en)
|
2019-09-06 |
2021-03-11 |
Obsidian Therapeutics, Inc. |
Compositions and methods for dhfr tunable protein regulation
|
JP2022550599A
(ja)
|
2019-10-03 |
2022-12-02 |
アーティサン ディベロップメント ラブズ インコーポレイテッド |
操作されたデュアルガイド核酸を有するcrisprシステム
|
EP3808766A1
(en)
|
2019-10-15 |
2021-04-21 |
Sangamo Therapeutics France |
Chimeric antigen receptor specific for interleukin-23 receptor
|
WO2021096868A1
(en)
|
2019-11-12 |
2021-05-20 |
A2 Biotherapeutics, Inc. |
Engineered t cell receptors and uses thereof
|
US11975026B2
(en)
|
2019-11-26 |
2024-05-07 |
Novartis Ag |
CD19 and CD22 chimeric antigen receptors and uses thereof
|
CN114761037A
(zh)
|
2019-11-26 |
2022-07-15 |
诺华股份有限公司 |
结合bcma和cd19的嵌合抗原受体及其用途
|
WO2021123832A1
(en)
|
2019-12-20 |
2021-06-24 |
Instil Bio (Uk) Limited |
Devices and methods for isolating tumor infiltrating lymphocytes and uses thereof
|
US20230141511A1
(en)
|
2019-12-20 |
2023-05-11 |
Ludwig Institute For Cancer Research Ltd |
Car-t cell therapy targeting ngcgm3
|
JP7088902B2
(ja)
*
|
2019-12-27 |
2022-06-21 |
クレージュ メディカル カンパニー,リミテッド |
キメラ抗原受容体タンパク質をコードする核酸およびキメラ抗原受容体タンパク質を発現するtリンパ球
|
EP4104187A1
(en)
|
2020-02-14 |
2022-12-21 |
Novartis AG |
Method of predicting response to chimeric antigen receptor therapy
|
CN115768463A
(zh)
|
2020-02-21 |
2023-03-07 |
哈普恩治疗公司 |
Flt3结合蛋白及使用方法
|
WO2021173995A2
(en)
|
2020-02-27 |
2021-09-02 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
CA3173394A1
(en)
|
2020-02-27 |
2021-09-02 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
KR20220150353A
(ko)
|
2020-03-05 |
2022-11-10 |
네오티엑스 테라퓨틱스 엘티디. |
면역 세포를 사용하여 암을 치료하기 위한 방법 및 조성물
|
AU2021237790A1
(en)
|
2020-03-20 |
2022-10-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Chimeric antigen receptor specific for human CD45RC and uses thereof
|
AU2021246112A1
(en)
|
2020-04-03 |
2022-11-10 |
Cellvie Inc. |
Enhancement of adoptive cell transfer
|
WO2021221783A1
(en)
|
2020-05-01 |
2021-11-04 |
Massachusetts Institute Of Technology |
Methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
|
JP2023529211A
(ja)
|
2020-06-11 |
2023-07-07 |
ノバルティス アーゲー |
Zbtb32阻害剤及びその使用
|
EP4196493A1
(en)
|
2020-08-13 |
2023-06-21 |
A2 Biotherapeutics, Inc. |
Gene fusions for control of genetically modified cells
|
EP4211228A1
(en)
|
2020-09-08 |
2023-07-19 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
T cell phenotypes associated with response to adoptive cell therapy
|
US20220090015A1
(en)
|
2020-09-21 |
2022-03-24 |
A2 Biotherapeutics, Inc. |
Engineered immune cells with multiplex and localized activity
|
EP4243937A2
(en)
|
2020-11-13 |
2023-09-20 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Enhanced antigen reactivity of immune cells expressing a mutant non-signaling cd3 zeta chain
|
CA3198447A1
(en)
|
2020-11-13 |
2022-05-19 |
Novartis Ag |
Combination therapies with chimeric antigen receptor (car)-expressing cells
|
GB202018554D0
(en)
|
2020-11-25 |
2021-01-06 |
Cancer Research Tech Ltd |
Nucleic acid constructs and cells
|
US11661459B2
(en)
|
2020-12-03 |
2023-05-30 |
Century Therapeutics, Inc. |
Artificial cell death polypeptide for chimeric antigen receptor and uses thereof
|
US11883432B2
(en)
|
2020-12-18 |
2024-01-30 |
Century Therapeutics, Inc. |
Chimeric antigen receptor system with adaptable receptor specificity
|
CN114807042A
(zh)
*
|
2021-01-22 |
2022-07-29 |
南京助天中科科技发展有限公司 |
一种嵌合抗原受体改造的nk细胞及其制备方法与应用
|
WO2022256448A2
(en)
|
2021-06-01 |
2022-12-08 |
Artisan Development Labs, Inc. |
Compositions and methods for targeting, editing, or modifying genes
|
TW202307210A
(zh)
|
2021-06-01 |
2023-02-16 |
瑞士商諾華公司 |
Cd19和cd22嵌合抗原受體及其用途
|
WO2022266538A2
(en)
|
2021-06-18 |
2022-12-22 |
Artisan Development Labs, Inc. |
Compositions and methods for targeting, editing or modifying human genes
|
KR20240026507A
(ko)
|
2021-06-29 |
2024-02-28 |
플래그쉽 파이어니어링 이노베이션스 브이, 인크. |
타노트랜스미션을 촉진시키도록 엔지니어링된 면역 세포 및 이의 용도
|
WO2023021113A1
(en)
|
2021-08-18 |
2023-02-23 |
Julius-Maximilians-Universität Würzburg |
Hybrid tumor/cancer therapy based on targeting the resolution of or inducing transcription-replication conflicts (trcs)
|
TW202323521A
(zh)
|
2021-08-20 |
2023-06-16 |
瑞士商諾華公司 |
製備表現嵌合抗原受體的細胞之方法
|
WO2023041717A1
(en)
|
2021-09-16 |
2023-03-23 |
Aboleris Pharma |
Anti-human cd45rc binding domains and uses thereof
|
CA3233989A1
(en)
|
2021-10-06 |
2023-04-13 |
Nina DUMAUTHIOZ |
Enhancing adoptive cell transfer by promoting a superior population of adaptive immune cells
|
WO2023130040A2
(en)
|
2021-12-31 |
2023-07-06 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
T cell therapy with vaccination as a combination immunotherapy against cancer
|
WO2023167882A1
(en)
|
2022-03-01 |
2023-09-07 |
Artisan Development Labs, Inc. |
Composition and methods for transgene insertion
|
WO2024056809A1
(en)
|
2022-09-15 |
2024-03-21 |
Novartis Ag |
Treatment of autoimmune disorders using chimeric antigen receptor therapy
|