HK1245840A1 - 使用嵌合細胞因子受體逆轉腫瘤微環境的影響 - Google Patents

使用嵌合細胞因子受體逆轉腫瘤微環境的影響

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Publication number
HK1245840A1
HK1245840A1 HK18105460.0A HK18105460A HK1245840A1 HK 1245840 A1 HK1245840 A1 HK 1245840A1 HK 18105460 A HK18105460 A HK 18105460A HK 1245840 A1 HK1245840 A1 HK 1245840A1
Authority
HK
Hong Kong
Prior art keywords
reversing
effects
tumor microenvironment
cytokine receptors
chimeric cytokine
Prior art date
Application number
HK18105460.0A
Other languages
English (en)
Inventor
Ann Marie Leen
Juan F Vera
Original Assignee
Baylor College Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baylor College Medicine filed Critical Baylor College Medicine
Publication of HK1245840A1 publication Critical patent/HK1245840A1/zh

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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
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HK18105460.0A 2011-04-08 2014-08-07 使用嵌合細胞因子受體逆轉腫瘤微環境的影響 HK1245840A1 (zh)

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US (2) US10548921B2 (zh)
EP (2) EP2694640B1 (zh)
JP (3) JP6066991B2 (zh)
CN (2) CN103582699B (zh)
AU (3) AU2012240135B2 (zh)
CA (1) CA2832569A1 (zh)
DK (1) DK2694640T3 (zh)
ES (1) ES2649967T3 (zh)
HK (1) HK1245840A1 (zh)
MX (1) MX347656B (zh)
NO (1) NO2724929T3 (zh)
NZ (3) NZ616405A (zh)
WO (1) WO2012138858A1 (zh)

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US10155038B2 (en) 2007-02-02 2018-12-18 Yale University Cells prepared by transient transfection and methods of use thereof
US9249423B2 (en) 2007-02-02 2016-02-02 Yale University Method of de-differentiating and re-differentiating somatic cells using RNA
US8956860B2 (en) 2009-12-08 2015-02-17 Juan F. Vera Methods of cell culture for adoptive cell therapy
JP5947311B2 (ja) 2010-12-09 2016-07-06 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア 癌を治療するためのキメラ抗原受容体改変ｔ細胞の使用
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