HK1215261A1 - 針對與肝素複合的抗凝血酶β的單克隆抗體 - Google Patents

針對與肝素複合的抗凝血酶β的單克隆抗體 Download PDF

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Publication number
HK1215261A1
HK1215261A1 HK16103100.3A HK16103100A HK1215261A1 HK 1215261 A1 HK1215261 A1 HK 1215261A1 HK 16103100 A HK16103100 A HK 16103100A HK 1215261 A1 HK1215261 A1 HK 1215261A1
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HK
Hong Kong
Prior art keywords
seq
antibody
amino acids
amino acid
nos
Prior art date
Application number
HK16103100.3A
Other languages
English (en)
Chinese (zh)
Inventor
Ye Jin
John E. Murphy
Terry Hermiston
Timothy MYLES
Frank Dittmer
Michael Strerath
Uwe Gritzan
Original Assignee
Bayer Healthcare Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50680168&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1215261(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Healthcare Llc filed Critical Bayer Healthcare Llc
Publication of HK1215261A1 publication Critical patent/HK1215261A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/38—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/32—Immunoglobulins specific features characterized by aspects of specificity or valency specific for a neo-epitope on a complex, e.g. antibody-antigen or ligand-receptor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK16103100.3A 2013-03-14 2014-03-14 針對與肝素複合的抗凝血酶β的單克隆抗體 HK1215261A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361784590P 2013-03-14 2013-03-14
US61/784590 2013-03-14
PCT/US2014/029541 WO2014153195A1 (en) 2013-03-14 2014-03-14 Monoclonal antibodies against antithrombin beta complexed with heparin

Publications (1)

Publication Number Publication Date
HK1215261A1 true HK1215261A1 (zh) 2016-08-19

Family

ID=50680168

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16103100.3A HK1215261A1 (zh) 2013-03-14 2014-03-14 針對與肝素複合的抗凝血酶β的單克隆抗體

Country Status (18)

Country Link
US (4) US9908942B2 (cg-RX-API-DMAC7.html)
EP (1) EP2970500A1 (cg-RX-API-DMAC7.html)
JP (1) JP2016519081A (cg-RX-API-DMAC7.html)
KR (1) KR20150127202A (cg-RX-API-DMAC7.html)
CN (1) CN105229033B (cg-RX-API-DMAC7.html)
AR (1) AR095499A1 (cg-RX-API-DMAC7.html)
AU (1) AU2014236198A1 (cg-RX-API-DMAC7.html)
BR (1) BR112015021399A2 (cg-RX-API-DMAC7.html)
CA (1) CA2916421A1 (cg-RX-API-DMAC7.html)
HK (1) HK1215261A1 (cg-RX-API-DMAC7.html)
MX (1) MX2015012441A (cg-RX-API-DMAC7.html)
PE (1) PE20160533A1 (cg-RX-API-DMAC7.html)
RU (1) RU2015143696A (cg-RX-API-DMAC7.html)
SG (1) SG11201506886TA (cg-RX-API-DMAC7.html)
TW (1) TW201529602A (cg-RX-API-DMAC7.html)
UY (1) UY35457A (cg-RX-API-DMAC7.html)
WO (1) WO2014153195A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201507628B (cg-RX-API-DMAC7.html)

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* Cited by examiner, † Cited by third party
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UY35457A (es) 2013-03-14 2014-10-31 Bayer Healthcare Llc ANTICUERPOS MONOCLONALES CONTRA ANTITROMBINA ß
EP3146759B1 (en) * 2014-05-19 2021-04-07 Nokia Solutions and Networks Oy Re-establishment procedure in dual connectivity networks
MY193078A (en) 2015-06-24 2022-09-26 Hoffmann La Roche Anti-transferrin receptor antibodies with tailored affinity
CN108137697A (zh) 2015-10-02 2018-06-08 豪夫迈·罗氏有限公司 双特异性抗人cd20/人转铁蛋白受体抗体及使用方法
AR106189A1 (es) 2015-10-02 2017-12-20 Hoffmann La Roche ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO
JP2019516347A (ja) * 2016-03-18 2019-06-20 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル 抗アンチトロンビン単一ドメイン抗体及びそれを含むポリペプチド

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Also Published As

Publication number Publication date
TW201529602A (zh) 2015-08-01
BR112015021399A2 (pt) 2017-07-18
RU2015143696A (ru) 2017-04-19
ZA201507628B (en) 2017-11-29
US9908942B2 (en) 2018-03-06
US10144784B2 (en) 2018-12-04
MX2015012441A (es) 2016-08-08
US9593166B2 (en) 2017-03-14
PE20160533A1 (es) 2016-06-09
CN105229033A (zh) 2016-01-06
US20160024222A1 (en) 2016-01-28
CN105229033B (zh) 2019-04-23
US20140271660A1 (en) 2014-09-18
AR095499A1 (es) 2015-10-21
US20140271661A1 (en) 2014-09-18
WO2014153195A1 (en) 2014-09-25
AU2014236198A1 (en) 2015-10-15
CA2916421A1 (en) 2014-09-25
EP2970500A1 (en) 2016-01-20
US20180244799A1 (en) 2018-08-30
JP2016519081A (ja) 2016-06-30
KR20150127202A (ko) 2015-11-16
UY35457A (es) 2014-10-31
SG11201506886TA (en) 2015-09-29

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