HK1213494A1 - 治療阿爾茨海默病及相關疾病的組合療法 - Google Patents
治療阿爾茨海默病及相關疾病的組合療法Info
- Publication number
- HK1213494A1 HK1213494A1 HK16101610.0A HK16101610A HK1213494A1 HK 1213494 A1 HK1213494 A1 HK 1213494A1 HK 16101610 A HK16101610 A HK 16101610A HK 1213494 A1 HK1213494 A1 HK 1213494A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- treatment
- related disorders
- combination therapies
- alzheimers disease
- alzheimers
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/047—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/075—Ethers or acetals
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- A61K31/13—Amines
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
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- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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- A61K31/425—Thiazoles
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
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- A61K51/04—Organic compounds
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- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
- A61K51/0453—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
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- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
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- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261718303P | 2012-10-25 | 2012-10-25 | |
PCT/US2013/066069 WO2014066318A1 (en) | 2012-10-25 | 2013-10-22 | Combination therapies for the treatment of alzheimer's disease and related disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1213494A1 true HK1213494A1 (zh) | 2016-07-08 |
Family
ID=50545170
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16100526.5A HK1212603A1 (zh) | 2012-10-25 | 2016-01-18 | 治療阿爾茨海默病及相關疾病的組合療法 |
HK16101610.0A HK1213494A1 (zh) | 2012-10-25 | 2016-02-15 | 治療阿爾茨海默病及相關疾病的組合療法 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK16100526.5A HK1212603A1 (zh) | 2012-10-25 | 2016-01-18 | 治療阿爾茨海默病及相關疾病的組合療法 |
Country Status (9)
Country | Link |
---|---|
US (17) | US9855276B2 (zh) |
EP (2) | EP3563849A3 (zh) |
JP (3) | JP6499077B2 (zh) |
CN (2) | CN109846862A (zh) |
AU (3) | AU2013334874B2 (zh) |
CA (2) | CA3111941A1 (zh) |
ES (1) | ES2749096T3 (zh) |
HK (2) | HK1212603A1 (zh) |
WO (1) | WO2014066318A1 (zh) |
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US9925282B2 (en) | 2009-01-29 | 2018-03-27 | The General Hospital Corporation | Cromolyn derivatives and related methods of imaging and treatment |
US10058530B2 (en) | 2012-10-25 | 2018-08-28 | The General Hospital Corporation | Combination therapies for the treatment of Alzheimer's disease and related disorders |
JP6499077B2 (ja) | 2012-10-25 | 2019-04-10 | ザ ジェネラル ホスピタル コーポレイション | アルツハイマー病と関連疾患の治療のための併用療法 |
CA2913235C (en) * | 2013-05-23 | 2021-07-13 | Aztherapies, Inc. | Methods for delivering cromolyn |
US10525005B2 (en) | 2013-05-23 | 2020-01-07 | The General Hospital Corporation | Cromolyn compositions and methods thereof |
EP3751283A3 (en) | 2013-07-11 | 2021-03-24 | University of North Texas Health Science Center at Fort Worth | Blood-based screen for detecting neurological diseases in primary care settings |
CN110305095A (zh) * | 2013-10-22 | 2019-10-08 | 综合医院公司 | 色甘酸衍生物以及成像和治疗的相关方法 |
WO2022187670A1 (en) * | 2021-03-05 | 2022-09-09 | University Of North Texas Health Science Center At Fort Worth | Personalized medicine approach for treating cognitive loss |
EP3074525B1 (en) | 2013-11-26 | 2024-06-26 | University of North Texas Health Science Center at Fort Worth | Personalized medicine approach for treating cognitive loss |
PT3104853T (pt) | 2014-02-10 | 2020-01-14 | Respivant Sciences Gmbh | Tratamento com estabilizadores de mastócitos para distúrbios sistémicos |
ES2792682T3 (es) | 2014-02-10 | 2020-11-11 | Respivant Sciences Gmbh | Métodos para el tratamiento de enfermedades pulmonares con estabilizadores de mastocitos |
GB201512203D0 (en) | 2015-07-13 | 2015-08-19 | Lundbeck & Co As H | Agents,uses and methods |
US10265296B2 (en) | 2015-08-07 | 2019-04-23 | Respivant Sciences Gmbh | Methods for the treatment of systemic disorders treatable with mast cell stabilizers, including mast cell related disorders |
EP3331522A1 (en) | 2015-08-07 | 2018-06-13 | Patara Pharma LLC | Methods for the treatment of mast cell related disorders with mast cell stabilizers |
CN114042061A (zh) * | 2015-11-19 | 2022-02-15 | 通用医院有限公司 | 包含色甘酸的组合物在制备用于治疗非遗忘性轻度认知障碍的药物中的用途 |
JP2018538273A (ja) * | 2015-11-23 | 2018-12-27 | エーゼットセラピーズ, インコーポレイテッド | 虚血性脳卒中を処置するための組成物および方法 |
WO2017096158A1 (en) | 2015-12-04 | 2017-06-08 | 10X Genomics, Inc. | Methods and compositions for nucleic acid analysis |
CA3035528A1 (en) | 2016-08-31 | 2018-03-08 | Respivant Sciences Gmbh | Cromolyn compositions for treatment of chronic cough due to idiopathic pulmonary fibrosis |
JP2019524865A (ja) * | 2016-08-31 | 2019-09-05 | ザ ジェネラル ホスピタル コーポレイション | 神経変性疾患と関連する神経炎症におけるマクロファージ/ミクログリア |
CN109803724A (zh) | 2016-10-07 | 2019-05-24 | 瑞思皮万特科学有限责任公司 | 用于治疗肺纤维化的色甘酸组合物 |
RU2019114679A (ru) * | 2016-11-15 | 2020-12-17 | Х. Лундбекк А/С | Средства, пути применения и способы лечения синуклеопатии |
AU2017423862A1 (en) | 2017-07-20 | 2020-02-06 | Aztherapies, Inc. | Powdered formulations of cromolyn sodium and ibuprofen |
CN111629719A (zh) * | 2017-12-04 | 2020-09-04 | 通用医疗公司 | 色甘酸组合物及其方法 |
JP7412003B2 (ja) * | 2018-01-18 | 2024-01-12 | ユニバーシティー オブ ノース テキサス ヘルス サイエンス センター アット フォートワース | アルツハイマー病に罹患している患者の特定の亜集団を治療するためのnsaid及びドネペジルについてのコンパニオン診断 |
EP3746057B1 (en) * | 2018-01-31 | 2024-03-20 | Olatec Therapeutics, Inc. | Dapansutrile for preventing or treating alzheimer's disease |
WO2019199776A1 (en) * | 2018-04-09 | 2019-10-17 | The General Hospital Corporation | Combination therapies for the treatment of amyotropic lateral sclerosis and related disorders |
JP2021529771A (ja) | 2018-07-02 | 2021-11-04 | ザ ジェネラル ホスピタル コーポレイション | クロモリンナトリウムおよびα−ラクトースの粉末製剤 |
US20220218652A1 (en) * | 2018-09-05 | 2022-07-14 | The General Hospital Corporation | Methods of treating cytokine release syndrome |
CU24626B1 (es) | 2019-12-26 | 2022-11-07 | Centro Nac De Biopreparados | Composición farmacéutica a base de proteínas con actividad neuroprotectora, inmunomoduladora, antiinflamatoria y antimicrobiana |
WO2023283425A1 (en) | 2021-07-09 | 2023-01-12 | Plexium, Inc. | Aryl compounds and pharmaceutical compositions that modulate ikzf2 |
WO2024050028A1 (en) * | 2022-08-31 | 2024-03-07 | Bioxcel Therapeutics, Inc. | Methods and compositions for treating acute stress disorder |
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