HK1209134A1 - Non-natural consensus albumin binding domains - Google Patents

Non-natural consensus albumin binding domains

Info

Publication number
HK1209134A1
HK1209134A1 HK15109729.2A HK15109729A HK1209134A1 HK 1209134 A1 HK1209134 A1 HK 1209134A1 HK 15109729 A HK15109729 A HK 15109729A HK 1209134 A1 HK1209134 A1 HK 1209134A1
Authority
HK
Hong Kong
Prior art keywords
binding domains
albumin binding
natural consensus
consensus albumin
natural
Prior art date
Application number
HK15109729.2A
Other languages
English (en)
Chinese (zh)
Inventor
Steven Jacobs
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of HK1209134A1 publication Critical patent/HK1209134A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/31Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
HK15109729.2A 2012-05-25 2015-10-06 Non-natural consensus albumin binding domains HK1209134A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261651642P 2012-05-25 2012-05-25
US201361776918P 2013-03-12 2013-03-12
PCT/US2013/042429 WO2013177398A2 (en) 2012-05-25 2013-05-23 Non-natural consensus albumin binding domains

Publications (1)

Publication Number Publication Date
HK1209134A1 true HK1209134A1 (en) 2016-03-24

Family

ID=49622071

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15109729.2A HK1209134A1 (en) 2012-05-25 2015-10-06 Non-natural consensus albumin binding domains

Country Status (16)

Country Link
US (3) US9156887B2 (ko)
EP (1) EP2855509B1 (ko)
JP (3) JP2015519345A (ko)
KR (1) KR102053674B1 (ko)
CN (1) CN104470944B (ko)
AU (2) AU2013266215B2 (ko)
BR (1) BR112014029409B1 (ko)
CA (1) CA2874646C (ko)
DK (1) DK2855509T3 (ko)
EA (1) EA036487B1 (ko)
ES (1) ES2670442T3 (ko)
HK (1) HK1209134A1 (ko)
IL (2) IL235808A (ko)
MX (1) MX355041B (ko)
PT (1) PT2855509T (ko)
WO (1) WO2013177398A2 (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9695228B2 (en) 2012-11-21 2017-07-04 Janssen Biotech, Inc. EGFR and c-Met fibronectin type III domain binding molecules
CA2902789A1 (en) * 2013-03-14 2014-09-18 The Governing Council Of The University Of Toronto Scaffolded peptidic libraries and methods of making and screening the same
SI3288965T1 (sl) * 2015-04-29 2019-10-30 Mediolanum Farm S P A Topljiv himerni receptor interleukina-10 in njegova terapevtska uporaba
US10456442B2 (en) * 2015-06-18 2019-10-29 Albert Einstein College Of Medicine FGF receptor ligands for treating diabetes and obesity
CN106699842B (zh) * 2015-11-17 2020-06-12 上海交通大学 一种新的抗炎小分子多肽及其应用
CA3054286A1 (en) 2016-03-01 2017-09-08 The Board Of Trustees Of The University Of Illinois L-asparaginase variants and fusion proteins with reduced l-glutaminase activity and enhanced stability
JP7104703B2 (ja) 2016-12-14 2022-07-21 ヤンセン バイオテツク,インコーポレーテツド Cd8a結合フィブロネクチンiii型ドメイン
US10611823B2 (en) 2016-12-14 2020-04-07 Hanssen Biotech, Inc CD137 binding fibronectin type III domains
WO2018140456A1 (en) 2017-01-24 2018-08-02 Northwestern University Active low molecular weight variants of angiotensin converting enzyme 2 (ace2)
AU2018313253A1 (en) 2017-08-11 2020-02-27 The Board Of Trustees Of The University Of Illinois Truncated guinea pig L-asparaginase variants and methods of use
US11505576B2 (en) 2018-03-13 2022-11-22 Affibody Ab Polypeptides based on a scaffold
KR102282240B1 (ko) * 2018-12-06 2021-07-28 경상국립대학교산학협력단 지속형 엑센딘-4 및 이의 용도
US11781138B2 (en) 2019-10-14 2023-10-10 Aro Biotherapeutics Company FN3 domain-siRNA conjugates and uses thereof
JP2022551204A (ja) 2019-10-14 2022-12-07 アロ・バイオセラピューティクス・カンパニー Cd71結合フィブロネクチンiii型ドメイン
AU2020405107A1 (en) * 2019-12-18 2022-07-14 Aro Biotherapeutics Company Serum albumin-binding fibronectin type III domains and uses thereof
CN113336860B (zh) * 2021-06-02 2022-07-01 北京大学 一种具有靶向和长效功能的重组水蛭素融合蛋白及其编码基因和应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6267964B1 (en) 1989-08-01 2001-07-31 Affibody Technology Sweden Ab Stabilized protein or peptide conjugates able to bond albumin having extended biological half-lives
WO1993022439A1 (en) * 1992-05-07 1993-11-11 Microbiological Research Authority Immunoglobulin binding proteins derived from l protein and their uses
WO1994012520A1 (en) 1992-11-20 1994-06-09 Enzon, Inc. Linker for linked fusion polypeptides
US6670127B2 (en) 1997-09-16 2003-12-30 Egea Biosciences, Inc. Method for assembly of a polynucleotide encoding a target polypeptide
DK1538206T3 (da) 1997-09-16 2010-07-12 Centocor Ortho Biotech Inc Fremgangsmåde til fuldstændig kemisk syntese og samling af gener og genomer
ATE422369T1 (de) 1999-12-24 2009-02-15 Genentech Inc Verfahren und zusammensetzungen zur verlängerung der entsorgungshalbwertszeit von biowirksamen verbindungen
US20050287153A1 (en) 2002-06-28 2005-12-29 Genentech, Inc. Serum albumin binding peptides for tumor targeting
CN104710518A (zh) 2007-07-31 2015-06-17 阿菲博迪公司 新白蛋白结合组合物、方法及应用
JP5425775B2 (ja) 2008-06-30 2014-02-26 協和発酵キリン株式会社 抗cd27抗体
ES2705714T3 (es) * 2008-10-31 2019-03-26 Janssen Biotech Inc Métodos y usos de dominio de Fibronectina tipo III basado en estructuras de composiciones
EP2397547A4 (en) * 2009-02-10 2012-09-05 Univ Ryukyus ACTIVE TRANSPORT, AS WELL AS AUXILIARY AND VACCINATE THEREOF
DK2396011T3 (en) 2009-02-12 2016-04-25 Janssen Biotech Inc Fibronectin TYPE III DOMAIN-BASED SCAFFOLD COMPOSITIONS, METHODS AND USES
ES2548030T3 (es) * 2009-06-01 2015-10-13 Medimmune, Llc Moléculas con semividas prolongadas y usos de las mismas
ES2608475T3 (es) 2010-04-13 2017-04-11 Celldex Therapeutics, Inc. Anticuerpos que se unen a cd27 humana y usos de los mismos
HUE029622T2 (en) * 2010-04-30 2017-03-28 Janssen Biotech Inc Stabilized fibronectin preparations, processes and applications
US9695228B2 (en) 2012-11-21 2017-07-04 Janssen Biotech, Inc. EGFR and c-Met fibronectin type III domain binding molecules

Also Published As

Publication number Publication date
WO2013177398A3 (en) 2014-03-27
EP2855509A2 (en) 2015-04-08
JP2018171063A (ja) 2018-11-08
US20160083436A1 (en) 2016-03-24
PT2855509T (pt) 2018-08-03
IL235808A0 (en) 2015-01-29
ES2670442T3 (es) 2018-05-30
EA036487B1 (ru) 2020-11-16
KR20150016585A (ko) 2015-02-12
EP2855509B1 (en) 2018-05-02
MX2014014384A (es) 2015-05-11
IL254652A0 (en) 2017-11-30
AU2013266215A1 (en) 2014-12-04
IL254652B (en) 2019-12-31
DK2855509T3 (en) 2018-07-23
CN104470944B (zh) 2021-09-14
IL235808A (en) 2017-10-31
AU2017261625A1 (en) 2017-12-07
JP7166081B2 (ja) 2022-11-07
AU2013266215B2 (en) 2017-12-07
CN104470944A (zh) 2015-03-25
JP2021019595A (ja) 2021-02-18
US20180009854A1 (en) 2018-01-11
US20130316952A1 (en) 2013-11-28
US10280200B2 (en) 2019-05-07
JP2015519345A (ja) 2015-07-09
WO2013177398A2 (en) 2013-11-28
MX355041B (es) 2018-03-28
BR112014029409A2 (ko) 2017-08-15
CA2874646C (en) 2020-12-01
KR102053674B1 (ko) 2019-12-09
AU2017261625B2 (en) 2019-11-21
BR112014029409B1 (pt) 2022-11-29
CA2874646A1 (en) 2013-11-28
EA201590136A1 (ru) 2016-02-29
US9156887B2 (en) 2015-10-13
EP2855509A4 (en) 2016-01-13

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