PT2855509T - Domínios de ligação à albumina de consenso não-natural - Google Patents

Domínios de ligação à albumina de consenso não-natural

Info

Publication number
PT2855509T
PT2855509T PT137935649T PT13793564T PT2855509T PT 2855509 T PT2855509 T PT 2855509T PT 137935649 T PT137935649 T PT 137935649T PT 13793564 T PT13793564 T PT 13793564T PT 2855509 T PT2855509 T PT 2855509T
Authority
PT
Portugal
Prior art keywords
binding domains
albumin binding
natural consensus
consensus albumin
natural
Prior art date
Application number
PT137935649T
Other languages
English (en)
Inventor
Jacobs Steven
Original Assignee
Janssen Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Biotech Inc filed Critical Janssen Biotech Inc
Publication of PT2855509T publication Critical patent/PT2855509T/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76Albumins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K19/00Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/31Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
PT137935649T 2012-05-25 2013-05-23 Domínios de ligação à albumina de consenso não-natural PT2855509T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261651642P 2012-05-25 2012-05-25
US201361776918P 2013-03-12 2013-03-12

Publications (1)

Publication Number Publication Date
PT2855509T true PT2855509T (pt) 2018-08-03

Family

ID=49622071

Family Applications (1)

Application Number Title Priority Date Filing Date
PT137935649T PT2855509T (pt) 2012-05-25 2013-05-23 Domínios de ligação à albumina de consenso não-natural

Country Status (16)

Country Link
US (3) US9156887B2 (pt)
EP (1) EP2855509B1 (pt)
JP (3) JP2015519345A (pt)
KR (1) KR102053674B1 (pt)
CN (1) CN104470944B (pt)
AU (2) AU2013266215B2 (pt)
BR (1) BR112014029409B1 (pt)
CA (1) CA2874646C (pt)
DK (1) DK2855509T3 (pt)
EA (1) EA036487B1 (pt)
ES (1) ES2670442T3 (pt)
HK (1) HK1209134A1 (pt)
IL (2) IL235808A (pt)
MX (1) MX355041B (pt)
PT (1) PT2855509T (pt)
WO (1) WO2013177398A2 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9695228B2 (en) 2012-11-21 2017-07-04 Janssen Biotech, Inc. EGFR and c-Met fibronectin type III domain binding molecules
CN105247118A (zh) * 2013-03-14 2016-01-13 多伦多大学管理委员会 支架化肽文库以及其制备和筛选方法
EP3288965B1 (en) * 2015-04-29 2019-06-26 Mediolanum Farmaceutici S.p.A. A soluble chimeric interleukin-10 receptor and therapeutic use thereof
US10456442B2 (en) * 2015-06-18 2019-10-29 Albert Einstein College Of Medicine FGF receptor ligands for treating diabetes and obesity
CN106699842B (zh) * 2015-11-17 2020-06-12 上海交通大学 一种新的抗炎小分子多肽及其应用
CA3054286A1 (en) 2016-03-01 2017-09-08 The Board Of Trustees Of The University Of Illinois L-asparaginase variants and fusion proteins with reduced l-glutaminase activity and enhanced stability
EP3554561B1 (en) 2016-12-14 2023-06-28 Janssen Biotech, Inc. Cd137 binding fibronectin type iii domains
US10626165B2 (en) 2016-12-14 2020-04-21 Janssen Biotech, Inc. CD8a-binding fibronectin type III domains
JP7332157B2 (ja) * 2017-01-24 2023-08-23 ノースウェスタン ユニバーシティ アンジオテンシン変換酵素2(ace2)の活性な低分子量変異体
EP3664832B1 (en) 2017-08-11 2023-10-18 The Board of Trustees of the University of Illinois Truncated guinea pig l-asparaginase variants and methods of use
EP3765496A1 (en) 2018-03-13 2021-01-20 Affibody AB Polypeptides based on a novel scaffold
KR102282240B1 (ko) * 2018-12-06 2021-07-28 경상국립대학교산학협력단 지속형 엑센딘-4 및 이의 용도
US11781138B2 (en) 2019-10-14 2023-10-10 Aro Biotherapeutics Company FN3 domain-siRNA conjugates and uses thereof
WO2021076546A1 (en) 2019-10-14 2021-04-22 Aro Biotherapeutics Company Cd71 binding fibronectin type iii domains
AU2020405107A1 (en) * 2019-12-18 2022-07-14 Aro Biotherapeutics Company Serum albumin-binding fibronectin type III domains and uses thereof
CN113336860B (zh) * 2021-06-02 2022-07-01 北京大学 一种具有靶向和长效功能的重组水蛭素融合蛋白及其编码基因和应用

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6267964B1 (en) 1989-08-01 2001-07-31 Affibody Technology Sweden Ab Stabilized protein or peptide conjugates able to bond albumin having extended biological half-lives
WO1993022439A1 (en) * 1992-05-07 1993-11-11 Microbiological Research Authority Immunoglobulin binding proteins derived from l protein and their uses
AU5670194A (en) 1992-11-20 1994-06-22 Enzon, Inc. Linker for linked fusion polypeptides
ATE462004T1 (de) 1997-09-16 2010-04-15 Centocor Inc Methoden zur kompletten chemischen synthese und zusammensetzung von genen und genomen
US6670127B2 (en) 1997-09-16 2003-12-30 Egea Biosciences, Inc. Method for assembly of a polynucleotide encoding a target polypeptide
PT1240337E (pt) 1999-12-24 2007-01-31 Genentech Inc Métodos e composições para prolongar as meias-vidas de eliminação de compostos bioactivos
US20050287153A1 (en) 2002-06-28 2005-12-29 Genentech, Inc. Serum albumin binding peptides for tumor targeting
ES2346178T3 (es) 2007-07-31 2015-11-02 Affibody Ab Nuevas composiciones, procedimientos y usos de unión de la albúmina
AU2009267294B2 (en) 2008-06-30 2014-06-26 Kyowa Kirin Co., Ltd. Anti-CD27 antibody
CN102307896B (zh) * 2008-10-31 2016-10-12 森托科尔奥索生物科技公司 基于iii型纤连蛋白结构域的支架组合物、方法及用途
EP2397547A4 (en) * 2009-02-10 2012-09-05 Univ Ryukyus ACTIVE TRANSPORT, AS WELL AS AUXILIARY AND VACCINATE THEREOF
EP2396011B1 (en) 2009-02-12 2016-04-13 Janssen Biotech, Inc. Fibronectin type iii domain based scaffold compositions, methods and uses
WO2010141329A1 (en) * 2009-06-01 2010-12-09 Medimmune, Llc Molecules with extended half-lives and uses thereof
ES2608475T3 (es) 2010-04-13 2017-04-11 Celldex Therapeutics, Inc. Anticuerpos que se unen a cd27 humana y usos de los mismos
EP3103478B1 (en) * 2010-04-30 2019-04-17 Janssen Biotech, Inc. Stabilized fibronectin domain compositions, methods and uses
US9695228B2 (en) 2012-11-21 2017-07-04 Janssen Biotech, Inc. EGFR and c-Met fibronectin type III domain binding molecules

Also Published As

Publication number Publication date
JP2018171063A (ja) 2018-11-08
CA2874646C (en) 2020-12-01
KR20150016585A (ko) 2015-02-12
JP7166081B2 (ja) 2022-11-07
CN104470944B (zh) 2021-09-14
KR102053674B1 (ko) 2019-12-09
IL235808A (en) 2017-10-31
JP2015519345A (ja) 2015-07-09
IL235808A0 (en) 2015-01-29
WO2013177398A3 (en) 2014-03-27
AU2013266215B2 (en) 2017-12-07
HK1209134A1 (en) 2016-03-24
BR112014029409B1 (pt) 2022-11-29
US10280200B2 (en) 2019-05-07
BR112014029409A2 (pt) 2017-08-15
IL254652A0 (en) 2017-11-30
US9156887B2 (en) 2015-10-13
EP2855509A2 (en) 2015-04-08
MX2014014384A (es) 2015-05-11
IL254652B (en) 2019-12-31
AU2017261625A1 (en) 2017-12-07
ES2670442T3 (es) 2018-05-30
CN104470944A (zh) 2015-03-25
MX355041B (es) 2018-03-28
WO2013177398A2 (en) 2013-11-28
CA2874646A1 (en) 2013-11-28
EP2855509A4 (en) 2016-01-13
US20130316952A1 (en) 2013-11-28
US20160083436A1 (en) 2016-03-24
AU2013266215A1 (en) 2014-12-04
EP2855509B1 (en) 2018-05-02
AU2017261625B2 (en) 2019-11-21
EA036487B1 (ru) 2020-11-16
DK2855509T3 (en) 2018-07-23
JP2021019595A (ja) 2021-02-18
EA201590136A1 (ru) 2016-02-29
US20180009854A1 (en) 2018-01-11

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