HK1150728A1 - Quinolone analogs and methods related thereto - Google Patents

Quinolone analogs and methods related thereto

Info

Publication number
HK1150728A1
HK1150728A1 HK11104885.7A HK11104885A HK1150728A1 HK 1150728 A1 HK1150728 A1 HK 1150728A1 HK 11104885 A HK11104885 A HK 11104885A HK 1150728 A1 HK1150728 A1 HK 1150728A1
Authority
HK
Hong Kong
Prior art keywords
methods related
quinolone analogs
quinolone
analogs
methods
Prior art date
Application number
HK11104885.7A
Other languages
English (en)
Chinese (zh)
Inventor
‧納卡薩瓦
‧皮埃爾
‧哈達奇
‧施瓦貝比
‧達加尼亞
‧惠藤
Original Assignee
生華生物科技股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 生華生物科技股份有限公司 filed Critical 生華生物科技股份有限公司
Publication of HK1150728A1 publication Critical patent/HK1150728A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
    • C07D513/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/16—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epidemiology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK11104885.7A 2007-10-05 2011-05-17 Quinolone analogs and methods related thereto HK1150728A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US97804207P 2007-10-05 2007-10-05
US3868108P 2008-03-21 2008-03-21
US4593308P 2008-04-17 2008-04-17
PCT/US2008/078859 WO2009046383A1 (en) 2007-10-05 2008-10-03 Quinolone analogs and methods related thereto

Publications (1)

Publication Number Publication Date
HK1150728A1 true HK1150728A1 (en) 2012-01-13

Family

ID=40523786

Family Applications (1)

Application Number Title Priority Date Filing Date
HK11104885.7A HK1150728A1 (en) 2007-10-05 2011-05-17 Quinolone analogs and methods related thereto

Country Status (19)

Country Link
US (2) US7928100B2 (no)
EP (2) EP2214491B1 (no)
JP (2) JP5824213B2 (no)
KR (2) KR101682867B1 (no)
CN (1) CN101888780B (no)
AU (1) AU2008308485B2 (no)
BR (1) BRPI0817806A2 (no)
CA (1) CA2701630C (no)
DK (1) DK3092901T3 (no)
ES (2) ES2791305T3 (no)
HK (1) HK1150728A1 (no)
IL (2) IL204844A (no)
MX (1) MX2010003685A (no)
NO (1) NO20100596L (no)
NZ (1) NZ584892A (no)
PL (2) PL2214491T3 (no)
PT (2) PT3092901T (no)
RU (1) RU2549895C2 (no)
WO (1) WO2009046383A1 (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110065687A1 (en) * 2007-04-17 2011-03-17 Michael Schwaebe Hydrazide compounds and uses thereof
RU2549895C2 (ru) * 2007-10-05 2015-05-10 Сенхва Байосайенсиз,Инк. Аналоги хинолона и относящиеся к ним способы
AR077974A1 (es) 2009-08-28 2011-10-05 Takeda Pharmaceutical Compuestos de hexahidrooxazinopterina para uso como inhibidores de mtor
ES2528948T3 (es) 2009-09-21 2015-02-13 Chemocentryx, Inc. Derivados de pirrolidinona carboxamida como moduladores de quemerina-R (ChemR23)
CN103384672B (zh) 2011-02-25 2016-09-28 武田药品工业株式会社 N-取代的噁嗪并喋啶和噁嗪并喋啶酮
WO2012123938A1 (en) 2011-03-17 2012-09-20 Tel Hashomer Medical Research Infrastructure And Services Ltd. Quinolone analogs for treating autoimmune diseases
GB201206384D0 (en) * 2012-04-11 2012-05-23 Redx Pharma Ltd Antibacterial drug derivatives
CN104177379B (zh) * 2013-05-22 2016-12-28 中国科学院上海药物研究所 一种喹诺酮类化合物或其立体化学异构体、包含该化合物的药物组合物及其用途
EP3074391B1 (en) * 2013-11-28 2019-07-31 Tel Hashomer Medical Research Infrastructure And Services Ltd. Rna polymerase i inhibitors and uses thereof
AU2015255738C1 (en) 2014-05-09 2017-09-28 Pimera, Inc. Novel compositions, uses and methods for making them
US9758518B2 (en) 2015-03-04 2017-09-12 Pimera, Inc. Compositions, uses and methods for making them
TWI730013B (zh) 2015-11-20 2021-06-11 生華生物科技股份有限公司 用於治療癌症的四環喹諾酮類似物組合療法
EP3394070B1 (en) * 2015-12-14 2023-08-02 Senhwa Biosciences, Inc. Crystalline forms of quinolone analogs and their salts
US9957282B2 (en) 2015-12-14 2018-05-01 Senhwa Biosciences, Inc. Crystalline forms of quinolone analogs and their salts
TWI765848B (zh) * 2015-12-14 2022-06-01 生華生物科技股份有限公司 喹諾酮類似物及其鹽的結晶形式
CA3057741A1 (en) 2017-03-28 2018-10-04 Pimera, Inc. Novel crystal forms of a pol1 inhibitor
US11071727B2 (en) 2018-01-26 2021-07-27 Northwestern University Therapeutic targeting of proteolytic cleavage of the mixed lineage leukemia gene product (MLL1) by taspase1 using kinase inhibitors
KR20200131251A (ko) * 2018-02-15 2020-11-23 센화 바이오사이언시즈 인코포레이티드 퀴놀론 유사체 및 이의 염, 조성물, 및 이들의 사용 방법
WO2020051342A1 (en) * 2018-09-06 2020-03-12 Cornell University Methods for treating metastatic disease using ribosome biogenesis inhibitor cx 5461
EP4013422A4 (en) * 2019-08-14 2023-08-09 Senhwa Biosciences, Inc. CRYSTALLINE FORMS OF QUINOLINE ANALOGUES AND THEIR SALTS, COMPOSITIONS AND THEIR METHODS OF USE
EP4013421A4 (en) * 2019-08-14 2023-08-23 Senhwa Biosciences, Inc. TETRACYCLIC COMPOUNDS AND THEIR SALTS, COMPOSITIONS AND METHODS OF USE
JP2020189888A (ja) * 2020-08-28 2020-11-26 センワ バイオサイエンシズ インコーポレイテッド キノロン類似体及びその塩の結晶形
CN114573604B (zh) * 2020-12-01 2024-06-18 中国科学院上海药物研究所 一类基于喹诺酮的化合物、其制备方法、包含其的药物组合物及其用途
AU2022239614A1 (en) 2021-03-19 2023-10-12 Icahn School Of Medicine At Mount Sinai Compounds for regulating trained immunity, and their methods of use
CN114409681A (zh) * 2022-03-18 2022-04-29 信义核新(北京)生物科技有限公司 用于治疗dna损伤修复缺陷肿瘤的喹诺酮类似物及其应用

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4559157A (en) 1983-04-21 1985-12-17 Creative Products Resource Associates, Ltd. Cosmetic applicator useful for skin moisturizing
LU84979A1 (fr) 1983-08-30 1985-04-24 Oreal Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux
US4820508A (en) 1987-06-23 1989-04-11 Neutrogena Corporation Skin protective composition
US4992478A (en) 1988-04-04 1991-02-12 Warner-Lambert Company Antiinflammatory skin moisturizing composition and method of preparing same
US4938949A (en) 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
EG20543A (en) * 1992-10-30 1999-07-31 Procter & Gamble Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones
JP4932994B2 (ja) 1999-04-07 2012-05-16 ユニバーシテイ・オブ・バージニア・パテント・フアウンデーシヨン 抗癌性カルシウムチャンネル遮断薬
JP2005511743A (ja) 2001-12-13 2005-04-28 ウォックハート・リミテッド 新世代の三重標的化したキラルな広域スペクトラム抗菌性の７位置換ピペリジノ−キノロンカルボン酸誘導体、その調製方法、組成物、および医薬としての使用
US6900224B2 (en) 2002-07-31 2005-05-31 The Procter & Gamble Company Antimicrobial quinolones, their compositions and uses
WO2005033108A1 (en) * 2003-09-22 2005-04-14 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
WO2006034113A2 (en) * 2004-09-17 2006-03-30 Cylene Pharmaceuticals, Inc. Quinolone analogs as cell proliferation inhibitors
DK1928887T3 (en) * 2005-08-05 2015-03-23 Senhwa Biosciences Inc Methods for preparing quinolonanaloger
WO2007022474A2 (en) * 2005-08-19 2007-02-22 Cylene Pharmaceuticals, Inc. HUMAN RIBOSOMAL DNA(rDNA) AND RIBOSOMAL RNA (rRNA) NUCLEIC ACIDS AND USES THEREOF
AR057555A1 (es) * 2005-10-27 2007-12-05 Merck Frosst Canada Ltd Un inhibidor de fosfodiesterasa-4 4-oxo-1-(3-sustituido fenil-1,4-dihidro-1,8-naftiridin-3-carboxamida y un procedimiento de preparacion del mismo
US20090291437A1 (en) * 2005-11-02 2009-11-26 O'brien Sean Methods for targeting quadruplex sequences
EP2023720A4 (en) * 2006-05-17 2009-06-10 Cylene Pharmaceuticals Inc TETRACYCLIC IMIDAZOLE ANALOGS
US20110112086A1 (en) 2006-06-08 2011-05-12 Cylene Pharmaceuticals, Inc. Pyridinone analogs
US20100305136A1 (en) * 2006-06-08 2010-12-02 Johnny Yasuo Nagasawa Quinolone analogs derivatized with sulfonic acid, sulfonate or sulfonamide
GB0701992D0 (en) 2007-02-02 2007-03-14 7Tm Pharma As Grehlin Receptor Modulators
US20110065687A1 (en) * 2007-04-17 2011-03-17 Michael Schwaebe Hydrazide compounds and uses thereof
RU2549895C2 (ru) * 2007-10-05 2015-05-10 Сенхва Байосайенсиз,Инк. Аналоги хинолона и относящиеся к ним способы

Also Published As

Publication number Publication date
KR101682867B1 (ko) 2016-12-05
ES2582662T3 (es) 2016-09-14
WO2009046383A1 (en) 2009-04-09
PL2214491T3 (pl) 2016-11-30
IL204844A (en) 2017-01-31
KR20100064392A (ko) 2010-06-14
IL204844A0 (en) 2010-11-30
EP3092901A1 (en) 2016-11-16
JP5824213B2 (ja) 2015-11-25
AU2008308485B2 (en) 2014-08-07
US7928100B2 (en) 2011-04-19
PT3092901T (pt) 2020-05-21
IL249906B (en) 2020-10-29
IL249906A0 (en) 2017-03-30
EP2214491B1 (en) 2016-07-13
PT2214491T (pt) 2016-10-25
AU2008308485A1 (en) 2009-04-09
CA2701630A1 (en) 2009-04-09
PL3092901T3 (pl) 2020-10-19
EP2214491A1 (en) 2010-08-11
RU2549895C2 (ru) 2015-05-10
MX2010003685A (es) 2010-06-02
NO20100596L (no) 2010-06-10
ES2791305T3 (es) 2020-11-03
DK3092901T3 (da) 2020-05-18
JP2014159474A (ja) 2014-09-04
BRPI0817806A2 (pt) 2014-10-07
EP3092901B1 (en) 2020-04-29
EP2214491A4 (en) 2010-11-10
JP2010540663A (ja) 2010-12-24
KR20160020578A (ko) 2016-02-23
US8853234B2 (en) 2014-10-07
CN101888780B (zh) 2014-08-13
US20110218184A1 (en) 2011-09-08
KR101601332B1 (ko) 2016-03-08
NZ584892A (en) 2012-06-29
CN101888780A (zh) 2010-11-17
RU2010117225A (ru) 2011-11-10
CA2701630C (en) 2016-10-25
US20090093455A1 (en) 2009-04-09

Similar Documents

Publication Publication Date Title
IL249906B (en) Quinolone analogs and methods related thereto
GB0706709D0 (en) Methods
EP2194044A4 (en) QUINOLONE DERIVATIVE
HK1132673A1 (en) Novel methods
GB2471221B (en) Methods
GB0818650D0 (en) Methods
ZA200906490B (en) New methods
HK1212698A1 (zh) 噻唑基和噁唑基異喹哪啶以及它們的使用方法
TWI370107B (en) Novel methods for making and using halosilylgermanes
GB0718160D0 (en) Methods
GB0811360D0 (en) Methods
IL205308A0 (en) Compounds and methods
EP2470022A4 (en) COMPOUNDS AND METHODS
GB201008346D0 (en) Methods and compounds for phototransfer
EP2161998A4 (en) NOVEL PROCEDURE
GB0903348D0 (en) Compounds and methods relating thereto
GB0715502D0 (en) Methods
GB0714842D0 (en) Methods
GB0707735D0 (en) Methods
GB0719252D0 (en) Methods
GB0713673D0 (en) Methods
GB0711140D0 (en) New methods
GB0712401D0 (en) Methods
GB0701417D0 (en) Methods
GB0700966D0 (en) Methods