HK1148006A1 - Isoquinoline modulators of atp-binding cassette transporters atp - Google Patents
Isoquinoline modulators of atp-binding cassette transporters atpInfo
- Publication number
- HK1148006A1 HK1148006A1 HK11102136A HK11102136A HK1148006A1 HK 1148006 A1 HK1148006 A1 HK 1148006A1 HK 11102136 A HK11102136 A HK 11102136A HK 11102136 A HK11102136 A HK 11102136A HK 1148006 A1 HK1148006 A1 HK 1148006A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- atp
- modulators
- binding cassette
- isoquinoline
- present
- Prior art date
Links
- 108010006533 ATP-Binding Cassette Transporters Proteins 0.000 title abstract 2
- 102000005416 ATP-Binding Cassette Transporters Human genes 0.000 title abstract 2
- AWJUIBRHMBBTKR-UHFFFAOYSA-N isoquinoline Chemical compound C1=NC=CC2=CC=CC=C21 AWJUIBRHMBBTKR-UHFFFAOYSA-N 0.000 title 2
- 102000012605 Cystic Fibrosis Transmembrane Conductance Regulator Human genes 0.000 abstract 2
- 108010079245 Cystic Fibrosis Transmembrane Conductance Regulator Proteins 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 108010078791 Carrier Proteins Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Neurology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Reproductive Health (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Obesity (AREA)
- Gynecology & Obstetrics (AREA)
- Oncology (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Otolaryngology (AREA)
- Cardiology (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US98855907P | 2007-11-16 | 2007-11-16 | |
PCT/US2008/083517 WO2009064959A1 (en) | 2007-11-16 | 2008-11-14 | Isoquinoline modulators of atp-binding cassette transporters |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1148006A1 true HK1148006A1 (en) | 2011-08-26 |
Family
ID=40303494
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK11102136A HK1148006A1 (en) | 2007-11-16 | 2011-03-03 | Isoquinoline modulators of atp-binding cassette transporters atp |
HK13104040.7A HK1177137A1 (en) | 2007-11-16 | 2013-04-02 | Isoquinoline modulators of atp-binding cassette transporters atp |
HK16110974.1A HK1222847A1 (zh) | 2007-11-16 | 2016-09-19 | 結合盒轉運蛋白的異喹啉調節劑 |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK13104040.7A HK1177137A1 (en) | 2007-11-16 | 2013-04-02 | Isoquinoline modulators of atp-binding cassette transporters atp |
HK16110974.1A HK1222847A1 (zh) | 2007-11-16 | 2016-09-19 | 結合盒轉運蛋白的異喹啉調節劑 |
Country Status (17)
Country | Link |
---|---|
US (4) | US8507524B2 (es) |
EP (3) | EP3012250B1 (es) |
JP (3) | JP5646338B2 (es) |
CN (2) | CN101952254B (es) |
AU (1) | AU2008322616B2 (es) |
CA (1) | CA2705562C (es) |
CY (1) | CY1115318T1 (es) |
DK (2) | DK2217572T3 (es) |
ES (3) | ES2556080T3 (es) |
HK (3) | HK1148006A1 (es) |
HR (2) | HRP20140103T1 (es) |
HU (1) | HUE026334T2 (es) |
NZ (2) | NZ598941A (es) |
PL (2) | PL2217572T3 (es) |
PT (2) | PT2578571E (es) |
SI (2) | SI2217572T1 (es) |
WO (1) | WO2009064959A1 (es) |
Families Citing this family (57)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
ZA200602755B (en) | 2003-09-06 | 2007-06-27 | Vertex Pharma | Modulators of ATP-binding cassette transporters |
CN101675928A (zh) * | 2003-11-14 | 2010-03-24 | 沃泰克斯药物股份有限公司 | 可用作atp-结合弹夹转运蛋白调控剂的噻唑和噁唑 |
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