HK1143823A1 - A gene encoding a multidrug resistance human p-glycoprotein homologue on chromosome 7p15-21 and uses thereof 7p15-21 p- - Google Patents

A gene encoding a multidrug resistance human p-glycoprotein homologue on chromosome 7p15-21 and uses thereof 7p15-21 p-

Info

Publication number
HK1143823A1
HK1143823A1 HK10110380.5A HK10110380A HK1143823A1 HK 1143823 A1 HK1143823 A1 HK 1143823A1 HK 10110380 A HK10110380 A HK 10110380A HK 1143823 A1 HK1143823 A1 HK 1143823A1
Authority
HK
Hong Kong
Prior art keywords
multidrug resistance
chromosome
glycoprotein
gene encoding
methods
Prior art date
Application number
HK10110380.5A
Other languages
English (en)
Chinese (zh)
Inventor
Markus H Frank
Mohamed H Sayegh
Original Assignee
Brigham & Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham & Womens Hospital Inc filed Critical Brigham & Womens Hospital Inc
Publication of HK1143823A1 publication Critical patent/HK1143823A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
HK10110380.5A 2000-06-05 2010-11-05 A gene encoding a multidrug resistance human p-glycoprotein homologue on chromosome 7p15-21 and uses thereof 7p15-21 p- HK1143823A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20891300P 2000-06-05 2000-06-05

Publications (1)

Publication Number Publication Date
HK1143823A1 true HK1143823A1 (en) 2011-01-14

Family

ID=22776565

Family Applications (2)

Application Number Title Priority Date Filing Date
HK10110380.5A HK1143823A1 (en) 2000-06-05 2010-11-05 A gene encoding a multidrug resistance human p-glycoprotein homologue on chromosome 7p15-21 and uses thereof 7p15-21 p-
HK18116046.0A HK1257165A1 (zh) 2000-06-05 2018-12-13 在染色體 7p15-21 上編碼多藥耐藥性人 p-糖蛋白同源染色體的基因及其用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK18116046.0A HK1257165A1 (zh) 2000-06-05 2018-12-13 在染色體 7p15-21 上編碼多藥耐藥性人 p-糖蛋白同源染色體的基因及其用途

Country Status (11)

Country Link
US (6) US6846883B2 (es)
EP (5) EP2230253B1 (es)
AT (1) ATE452909T1 (es)
CA (1) CA2411101C (es)
CY (2) CY1109941T1 (es)
DE (1) DE60140868D1 (es)
DK (4) DK2298799T3 (es)
ES (4) ES2338756T3 (es)
HK (2) HK1143823A1 (es)
PT (4) PT2182005E (es)
WO (1) WO2001094400A2 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2298799T3 (en) 2000-06-05 2018-02-19 Brigham & Womens Hospital Inc Gene encoding a human multi-resistance β-glycoprotein homolog on chromosome 7p15-21, and uses thereof
WO2003025174A2 (en) * 2001-09-06 2003-03-27 Bayer Healthcare Ag Regulation of human mrp1-like protein
PT2035549E (pt) 2006-05-31 2014-10-06 Childrens Medical Center Células estaminais mesenquimais abcb5 positivas como imunomoduladores
US7928202B2 (en) 2007-04-12 2011-04-19 The Brigham And Women's Hospital, Inc. Targeting ABCB5 for cancer therapy
US11542328B2 (en) 2008-11-14 2023-01-03 The Brigham And Women's Hospital, Inc. Therapeutic and diagnostic methods relating to cancer stem cells
EP3734281A3 (en) 2008-11-14 2021-01-27 The Brigham and Women's Hospital, Inc. Therapeutic and diagnostic methods relating to cancer stem cells
AU2014219026B2 (en) 2013-02-19 2018-11-29 Children's Medical Center Corporation ABCB5(+) stem cells for treating ocular disease
AU2014262590B2 (en) 2013-05-10 2018-05-10 Children's Medical Center Corporation Wound healing and tissue engineering
US11382931B2 (en) * 2016-07-14 2022-07-12 University Of Southern California Methods and composition for producing and using immune cells and stem cells for cell-based therapies
CN116096753A (zh) * 2020-04-30 2023-05-09 儿童医学中心公司 对abcb5具有特异性的抗体及其用途

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EP0174810B1 (en) * 1984-09-10 1993-07-21 HSC Research Development Corporation Multidrug resistance in mammalian cell lines and isolation of determinant glycoprotein dna
US4837306A (en) * 1985-02-25 1989-06-06 The Ontario Cancer Institute Method for selecting hybridomas producing antibodies specific to the P-glycoprotein cell suface antigen and a cDNA clone encoding the C-terminal portion of the antigen
US5693622A (en) 1989-03-21 1997-12-02 Vical Incorporated Expression of exogenous polynucleotide sequences cardiac muscle of a mammal
US5399483A (en) 1989-03-30 1995-03-21 Suntory Limited Expression of MDR-related gene in yeast cell
US5264618A (en) 1990-04-19 1993-11-23 Vical, Inc. Cationic lipids for intracellular delivery of biologically active molecules
US5434075A (en) * 1992-03-20 1995-07-18 Board Of Trustees Of The University Of Illinois Monoclonal antibody to a human MDR1 multidrug resistance gene product, and uses
IT1257893B (it) * 1992-06-17 1996-02-16 Ist Superiore Sanita Anticorpi monoclonali che riconoscono un epitopo della p-glicoproteina umana.
WO1994009363A1 (en) * 1992-10-14 1994-04-28 Board Of Regents, The University Of Texas System Cancer diagnosis and therapy
ES2351684T3 (es) 1996-10-01 2011-02-09 Kyowa Hakko Kirin Co., Ltd. Compuestos heterocíclicos nitrogenados.
US6020191A (en) 1997-04-14 2000-02-01 Genzyme Corporation Adenoviral vectors capable of facilitating increased persistence of transgene expression
US6008002A (en) * 1997-09-29 1999-12-28 Bodey; Bela Immunomagnetic detection and isolation of cancer cells
SI1659179T1 (sl) * 1998-02-05 2011-10-28 Glaxosmithkline Biolog Sa S tumorjem povezani antigenski derivati iz MAGE druĹľine in zaporedja nukleinskih kislin, ki jih kodirajo, uporabni za pripravo fuzijskih proteinov in sestavkov za cepljenje
DE69922933T2 (de) 1998-03-13 2005-12-29 Osiris Therapeutics, Inc. Anwendungen für humane nicht autologe, mesenchymale stammzellen
AU785363B2 (en) * 1999-09-28 2007-02-01 Gentest Corporation P-glycoproteins and uses thereof
EP1290217A2 (en) * 2000-02-04 2003-03-12 Aeomica, Inc. Methods and apparatus for predicting, confirming, and displaying functional information derived from genomic sequence
DK2298799T3 (en) 2000-06-05 2018-02-19 Brigham & Womens Hospital Inc Gene encoding a human multi-resistance β-glycoprotein homolog on chromosome 7p15-21, and uses thereof
CA2412494C (en) 2000-06-22 2012-10-23 Genentech, Inc. Agonist anti-trk-c monoclonal antibodies
AU2002241569A1 (en) * 2000-10-27 2002-05-27 Incyte Genomics, Inc. Transporters and ion channels
AU2004295680A1 (en) * 2003-11-24 2005-06-16 The Rockefeller University A method for isolating a self-renewing, multipotent slow-cycling cell
US20050186672A1 (en) 2004-01-27 2005-08-25 Reliance Life Sciences Pvt. Ltd. Tissue system with undifferentiated stem cells derived from corneal limbus
CA2629330C (en) 2004-11-12 2018-05-22 Cambridge University Technical Services Ltd. Methods and means related to cancer stem cells
WO2006103685A2 (en) 2005-03-28 2006-10-05 Vision Research Foundation A method for cultivating cells derived from corneal limbal tissue and cells deived from corneal limbal tissue
US20070105133A1 (en) 2005-06-13 2007-05-10 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
PT2035549E (pt) 2006-05-31 2014-10-06 Childrens Medical Center Células estaminais mesenquimais abcb5 positivas como imunomoduladores
US20080118432A1 (en) * 2006-09-07 2008-05-22 Ivan Bergstein Monitoring cancer stem cells
US7928202B2 (en) * 2007-04-12 2011-04-19 The Brigham And Women's Hospital, Inc. Targeting ABCB5 for cancer therapy
EP3734281A3 (en) * 2008-11-14 2021-01-27 The Brigham and Women's Hospital, Inc. Therapeutic and diagnostic methods relating to cancer stem cells
AU2014219026B2 (en) 2013-02-19 2018-11-29 Children's Medical Center Corporation ABCB5(+) stem cells for treating ocular disease
AU2014262590B2 (en) 2013-05-10 2018-05-10 Children's Medical Center Corporation Wound healing and tissue engineering

Also Published As

Publication number Publication date
ATE452909T1 (de) 2010-01-15
DK2182005T3 (en) 2015-06-29
US20090162873A1 (en) 2009-06-25
US8076091B2 (en) 2011-12-13
EP1290028A2 (en) 2003-03-12
EP2230253A1 (en) 2010-09-22
EP2298799A1 (en) 2011-03-23
PT2230253E (pt) 2013-11-11
HK1257165A1 (zh) 2019-10-18
EP2230253B1 (en) 2013-08-07
CA2411101A1 (en) 2001-12-13
DK2230253T3 (da) 2013-11-18
WO2001094400A2 (en) 2001-12-13
US20020037522A1 (en) 2002-03-28
DE60140868D1 (de) 2010-02-04
US20120034196A1 (en) 2012-02-09
US20100145030A1 (en) 2010-06-10
CY1109941T1 (el) 2014-09-10
ES2338756T3 (es) 2010-05-12
PT2182005E (pt) 2015-07-20
EP2182005A1 (en) 2010-05-05
US20050049185A1 (en) 2005-03-03
WO2001094400A3 (en) 2002-07-04
US8507273B2 (en) 2013-08-13
ES2434721T3 (es) 2013-12-17
EP3333182A1 (en) 2018-06-13
DK2298799T3 (en) 2018-02-19
PT2298799T (pt) 2018-02-16
ES2540102T3 (es) 2015-07-08
ES2659877T3 (es) 2018-03-19
CA2411101C (en) 2018-01-16
US20130287785A1 (en) 2013-10-31
EP1290028B1 (en) 2009-12-23
EP2298799B1 (en) 2017-11-15
PT1290028E (pt) 2010-03-12
US6846883B2 (en) 2005-01-25
EP2182005B1 (en) 2015-03-25
US9561264B2 (en) 2017-02-07
CY1121053T1 (el) 2019-12-11
DK1290028T3 (da) 2010-04-26
US8425876B2 (en) 2013-04-23
US7465554B2 (en) 2008-12-16

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Legal Events

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PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20190604