ATE452909T1 - Für ein homologes des humanen, für mehrfachresistenz verantwortlichen, p- glykoproteins auf chromosom 7p15-21 kodierendes gen sowie verwendungen dafür - Google Patents

Für ein homologes des humanen, für mehrfachresistenz verantwortlichen, p- glykoproteins auf chromosom 7p15-21 kodierendes gen sowie verwendungen dafür

Info

Publication number
ATE452909T1
ATE452909T1 AT01941884T AT01941884T ATE452909T1 AT E452909 T1 ATE452909 T1 AT E452909T1 AT 01941884 T AT01941884 T AT 01941884T AT 01941884 T AT01941884 T AT 01941884T AT E452909 T1 ATE452909 T1 AT E452909T1
Authority
AT
Austria
Prior art keywords
chromosome
homologue
glycoproteins
multidrug resistance
human gene
Prior art date
Application number
AT01941884T
Other languages
English (en)
Inventor
Markus Frank
Mohamed Sayegh
Original Assignee
Brigham & Womens Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham & Womens Hospital filed Critical Brigham & Womens Hospital
Application granted granted Critical
Publication of ATE452909T1 publication Critical patent/ATE452909T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
AT01941884T 2000-06-05 2001-06-05 Für ein homologes des humanen, für mehrfachresistenz verantwortlichen, p- glykoproteins auf chromosom 7p15-21 kodierendes gen sowie verwendungen dafür ATE452909T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20891300P 2000-06-05 2000-06-05
PCT/US2001/018032 WO2001094400A2 (en) 2000-06-05 2001-06-05 A GENE ENCODING A MULTIDRUG RESISTANCE HUMAN P-GLYCOPROTEIN HOMOLOGUE ON CHROMOSOME 7p15-21 AND USES THEREOF

Publications (1)

Publication Number Publication Date
ATE452909T1 true ATE452909T1 (de) 2010-01-15

Family

ID=22776565

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01941884T ATE452909T1 (de) 2000-06-05 2001-06-05 Für ein homologes des humanen, für mehrfachresistenz verantwortlichen, p- glykoproteins auf chromosom 7p15-21 kodierendes gen sowie verwendungen dafür

Country Status (11)

Country Link
US (6) US6846883B2 (de)
EP (5) EP1290028B1 (de)
AT (1) ATE452909T1 (de)
CA (1) CA2411101C (de)
CY (2) CY1109941T1 (de)
DE (1) DE60140868D1 (de)
DK (4) DK1290028T3 (de)
ES (4) ES2434721T3 (de)
HK (2) HK1143823A1 (de)
PT (4) PT1290028E (de)
WO (1) WO2001094400A2 (de)

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DE60140868D1 (de) * 2000-06-05 2010-02-04 Brigham & Womens Hospital Für ein homologes des humanen, für mehrfachresistenz verantwortlichen, p-glykoproteins auf chromosom 7p15-21 kodierendes gen sowie verwendungen dafür
WO2003025174A2 (en) * 2001-09-06 2003-03-27 Bayer Healthcare Ag Regulation of human mrp1-like protein
EP2035549B1 (de) 2006-05-31 2014-07-09 Children's Medical Center Corporation Abcb5-positive mesenchymale stammzellen als immunmodulatoren
EP2644205B1 (de) 2007-04-12 2018-06-13 The Brigham and Women's Hospital, Inc. Anzielen von ABCB5 zur Krebstherapie
US11542328B2 (en) 2008-11-14 2023-01-03 The Brigham And Women's Hospital, Inc. Therapeutic and diagnostic methods relating to cancer stem cells
EP2356446A4 (de) 2008-11-14 2014-03-19 Brigham & Womens Hospital Therapeutische und diagnostische verfahren im zusammenhang mit krebsstammzellen
CA2901931C (en) 2013-02-19 2023-03-07 Children's Medical Center Corporation Abcb5(+) stem cells for treating ocular disease
JP6600299B2 (ja) 2013-05-10 2019-10-30 ザ チルドレンズ メディカル センター コーポレーション 創傷治癒および組織工学
CA3030603A1 (en) * 2016-07-14 2018-01-18 University Of Southern California Methods and composition for producing and using immune cells and stem cells for cell-based therapies
CN116096753A (zh) * 2020-04-30 2023-05-09 儿童医学中心公司 对abcb5具有特异性的抗体及其用途

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US4837306A (en) * 1985-02-25 1989-06-06 The Ontario Cancer Institute Method for selecting hybridomas producing antibodies specific to the P-glycoprotein cell suface antigen and a cDNA clone encoding the C-terminal portion of the antigen
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IT1257893B (it) * 1992-06-17 1996-02-16 Ist Superiore Sanita Anticorpi monoclonali che riconoscono un epitopo della p-glicoproteina umana.
WO1994009363A1 (en) * 1992-10-14 1994-04-28 Board Of Regents, The University Of Texas System Cancer diagnosis and therapy
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US6020191A (en) 1997-04-14 2000-02-01 Genzyme Corporation Adenoviral vectors capable of facilitating increased persistence of transgene expression
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ES2255248T3 (es) * 1998-02-05 2006-06-16 Glaxosmithkline Biologicals S.A. Derivados de antigenos asociados a tumor de la familia mage, y secuencias de acidos nucleicos que los codifican, usados para la preparacion de proteinas de fusion y de composiciones para vacunas.
DE69922933T2 (de) 1998-03-13 2005-12-29 Osiris Therapeutics, Inc. Anwendungen für humane nicht autologe, mesenchymale stammzellen
EP1220911B1 (de) * 1999-09-28 2006-11-29 Becton Dickinson and Company P-glycoproteine und ihre verwendungen
WO2001057252A2 (en) * 2000-02-04 2001-08-09 Aeomica, Inc. Methods and apparatus for high-throughput detection and characterization of alternatively spliced genes
DE60140868D1 (de) 2000-06-05 2010-02-04 Brigham & Womens Hospital Für ein homologes des humanen, für mehrfachresistenz verantwortlichen, p-glykoproteins auf chromosom 7p15-21 kodierendes gen sowie verwendungen dafür
AU2001271422B2 (en) 2000-06-22 2005-12-22 Genentech, Inc. Agonist anti-trk-C monoclonal antibodies
CA2427010A1 (en) * 2000-10-27 2002-05-23 Incyte Genomics, Inc. Transporters and ion channels
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WO2006103685A2 (en) 2005-03-28 2006-10-05 Vision Research Foundation A method for cultivating cells derived from corneal limbal tissue and cells deived from corneal limbal tissue
AU2006259583A1 (en) 2005-06-13 2006-12-28 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
EP2035549B1 (de) 2006-05-31 2014-07-09 Children's Medical Center Corporation Abcb5-positive mesenchymale stammzellen als immunmodulatoren
WO2008030616A2 (en) * 2006-09-07 2008-03-13 Stemline Therapeutics, Inc. Monitoring cancer stem cells
EP2644205B1 (de) * 2007-04-12 2018-06-13 The Brigham and Women's Hospital, Inc. Anzielen von ABCB5 zur Krebstherapie
EP2356446A4 (de) 2008-11-14 2014-03-19 Brigham & Womens Hospital Therapeutische und diagnostische verfahren im zusammenhang mit krebsstammzellen
CA2901931C (en) 2013-02-19 2023-03-07 Children's Medical Center Corporation Abcb5(+) stem cells for treating ocular disease
JP6600299B2 (ja) 2013-05-10 2019-10-30 ザ チルドレンズ メディカル センター コーポレーション 創傷治癒および組織工学

Also Published As

Publication number Publication date
US7465554B2 (en) 2008-12-16
HK1257165A1 (zh) 2019-10-18
EP2298799B1 (de) 2017-11-15
US6846883B2 (en) 2005-01-25
EP2298799A1 (de) 2011-03-23
CY1121053T1 (el) 2019-12-11
WO2001094400A2 (en) 2001-12-13
EP1290028B1 (de) 2009-12-23
ES2434721T3 (es) 2013-12-17
ES2338756T3 (es) 2010-05-12
PT2298799T (pt) 2018-02-16
HK1143823A1 (en) 2011-01-14
PT1290028E (pt) 2010-03-12
US20090162873A1 (en) 2009-06-25
US9561264B2 (en) 2017-02-07
CA2411101A1 (en) 2001-12-13
WO2001094400A3 (en) 2002-07-04
CY1109941T1 (el) 2014-09-10
US8425876B2 (en) 2013-04-23
US20130287785A1 (en) 2013-10-31
ES2540102T3 (es) 2015-07-08
ES2659877T3 (es) 2018-03-19
US20050049185A1 (en) 2005-03-03
PT2182005E (pt) 2015-07-20
US8076091B2 (en) 2011-12-13
US20100145030A1 (en) 2010-06-10
EP2182005B1 (de) 2015-03-25
DE60140868D1 (de) 2010-02-04
DK1290028T3 (da) 2010-04-26
EP1290028A2 (de) 2003-03-12
DK2298799T3 (en) 2018-02-19
CA2411101C (en) 2018-01-16
US8507273B2 (en) 2013-08-13
DK2230253T3 (da) 2013-11-18
DK2182005T3 (en) 2015-06-29
EP2230253B1 (de) 2013-08-07
US20120034196A1 (en) 2012-02-09
EP2230253A1 (de) 2010-09-22
EP2182005A1 (de) 2010-05-05
EP3333182A1 (de) 2018-06-13
PT2230253E (pt) 2013-11-11
US20020037522A1 (en) 2002-03-28

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