HK1137448A1 - Serine-threonine protein kinase and parp modulators - parp - Google Patents

Serine-threonine protein kinase and parp modulators - parp

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Publication number
HK1137448A1
HK1137448A1 HK10102364.2A HK10102364A HK1137448A1 HK 1137448 A1 HK1137448 A1 HK 1137448A1 HK 10102364 A HK10102364 A HK 10102364A HK 1137448 A1 HK1137448 A1 HK 1137448A1
Authority
HK
Hong Kong
Prior art keywords
parp
serine
protein kinase
modulators
threonine protein
Prior art date
Application number
HK10102364.2A
Other languages
English (en)
Chinese (zh)
Inventor
‧楚埃
‧皮埃爾
‧惠藤
Original Assignee
生華生物科技股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 生華生物科技股份有限公司 filed Critical 生華生物科技股份有限公司
Publication of HK1137448A1 publication Critical patent/HK1137448A1/xx

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
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    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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    • C07D221/06—Ring systems of three rings
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
HK10102364.2A 2006-09-01 2010-03-05 Serine-threonine protein kinase and parp modulators - parp HK1137448A1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US84206106P 2006-09-01 2006-09-01
US84454206P 2006-09-13 2006-09-13
US84668306P 2006-09-22 2006-09-22
US87393606P 2006-12-07 2006-12-07
US89571607P 2007-03-19 2007-03-19
PCT/US2007/077464 WO2008028168A2 (fr) 2006-09-01 2007-08-31 Sérine-thréonine protéine kinase et modulateurs parp

Publications (1)

Publication Number Publication Date
HK1137448A1 true HK1137448A1 (en) 2010-07-30

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
HK10102364.2A HK1137448A1 (en) 2006-09-01 2010-03-05 Serine-threonine protein kinase and parp modulators - parp

Country Status (17)

Country Link
US (2) US7956064B2 (fr)
EP (1) EP2061765B1 (fr)
JP (1) JP5399905B2 (fr)
KR (1) KR20090050094A (fr)
AU (1) AU2007289065B2 (fr)
BR (1) BRPI0719123A2 (fr)
CA (2) CA2974246C (fr)
DK (1) DK2061765T3 (fr)
ES (1) ES2528316T3 (fr)
HK (1) HK1137448A1 (fr)
IL (1) IL197088A0 (fr)
MX (1) MX2009002298A (fr)
NO (1) NO20090854L (fr)
PL (1) PL2061765T3 (fr)
PT (1) PT2061765E (fr)
RU (1) RU2681209C2 (fr)
WO (1) WO2008028168A2 (fr)

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CA2647391C (fr) 2006-04-04 2015-12-29 The Regents Of The University Of California Antagonistes de la kinase
AU2007289065B2 (en) 2006-09-01 2013-03-14 Senhwa Biosciences, Inc. Serine-threonine protein kinase and PARP modulators
US20110160232A1 (en) 2007-10-04 2011-06-30 Pingda Ren Certain chemical entities and therapeutic uses thereof
KR101897881B1 (ko) 2008-01-04 2018-09-12 인텔리카인, 엘엘씨 특정 화학 물질, 조성물 및 방법
US8193182B2 (en) 2008-01-04 2012-06-05 Intellikine, Inc. Substituted isoquinolin-1(2H)-ones, and methods of use thereof
EP2259678A4 (fr) * 2008-02-29 2011-07-27 Cylene Pharmaceuticals Inc Modulateurs de protéines kinases
WO2009114874A2 (fr) 2008-03-14 2009-09-17 Intellikine, Inc. Inhibiteurs de kinases (benzothiazole) et procédés d’utilisation associés
US8637542B2 (en) 2008-03-14 2014-01-28 Intellikine, Inc. Kinase inhibitors and methods of use
EP2303890A4 (fr) * 2008-06-19 2012-04-11 Progenics Pharm Inc Inhibiteurs de phosphatidylinositol 3 kinase
CN102124009B (zh) 2008-07-08 2014-07-23 因特利凯公司 激酶抑制剂及其使用方法
WO2010006072A2 (fr) 2008-07-08 2010-01-14 The Regents Of The University Of California Modulateurs de mtor et leurs utilisations
CA2735782A1 (fr) * 2008-09-02 2010-03-11 Novartis Ag Inhibiteurs heterocycliques de la kinase pim
US8703778B2 (en) 2008-09-26 2014-04-22 Intellikine Llc Heterocyclic kinase inhibitors
WO2010045542A2 (fr) 2008-10-16 2010-04-22 The Regents Of The University Of California Inhibiteurs d'hétéroarylkinase à noyau fusionné
US8476431B2 (en) 2008-11-03 2013-07-02 Itellikine LLC Benzoxazole kinase inhibitors and methods of use
BRPI0915273B1 (pt) * 2008-11-11 2021-08-03 Je Il Pharmaceutical Co., Ltd Derivado tricíclico ou seus sais farmaceuticamente aceitáveis e seus métodos de preparação
EP2367821B1 (fr) * 2008-12-17 2015-09-16 Merck Patent GmbH Inhibiteurs de protéines kinases de type benzonaphtyridinones tricycliques modifiées sur le noyau c et leur utilisation
EP2381942A1 (fr) * 2009-01-08 2011-11-02 Cylene Pharmaceuticals, Inc. Traitements combinés pour troubles néoplasiques
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