JPH0637520B2
(ja)
|
1985-07-03 |
1994-05-18 |
味の素株式会社 |
ポリペプチド
|
AU597574B2
(en)
|
1986-03-07 |
1990-06-07 |
Massachusetts Institute Of Technology |
Method for enhancing glycoprotein stability
|
US4973577A
(en)
|
1986-04-04 |
1990-11-27 |
The Salk Institute For Biological Studies |
FSH-releasing peptides
|
US5080891A
(en)
|
1987-08-03 |
1992-01-14 |
Ddi Pharmaceuticals, Inc. |
Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols
|
US5223409A
(en)
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
US5198346A
(en)
|
1989-01-06 |
1993-03-30 |
Protein Engineering Corp. |
Generation and selection of novel DNA-binding proteins and polypeptides
|
US5096815A
(en)
|
1989-01-06 |
1992-03-17 |
Protein Engineering Corporation |
Generation and selection of novel dna-binding proteins and polypeptides
|
EP0548276A4
(en)
|
1990-09-13 |
1993-12-29 |
Children's Hospital Medical Center Of Northern California |
Method for increasing red blood cell production by treatment with activin or activin-related peptides
|
US5118667A
(en)
|
1991-05-03 |
1992-06-02 |
Celtrix Pharmaceuticals, Inc. |
Bone growth factors and inhibitors of bone resorption for promoting bone formation
|
US6162896A
(en)
|
1991-05-10 |
2000-12-19 |
The Salk Institute For Biological Studies |
Recombinant vertebrate activin receptors
|
US5885794A
(en)
|
1991-05-10 |
1999-03-23 |
The Salk Institute For Biological Studies |
Recombinant production of vertebrate activin receptor polypeptides and identification of receptor DNAs in the activin/TGF-β superfamily
|
US20050186593A1
(en)
|
1991-05-10 |
2005-08-25 |
The Salk Institute For Biological Studies |
Cloning and recombinant production of CRF receptor(s)
|
WO1992020793A1
(en)
|
1991-05-10 |
1992-11-26 |
The Salk Institute For Biological Studies |
CLONING AND RECOMBINANT PRODUCTION OF RECEPTOR(S) OF THE ACTIVIN/TGF-β SUPERFAMILY
|
US6287816B1
(en)
|
1991-06-25 |
2001-09-11 |
Genetics Institute, Inc. |
BMP-9 compositions
|
JP3485917B2
(ja)
|
1991-06-25 |
2004-01-13 |
ジェネティックス・インスチチュート・リミテッド・ライアビリティ・カンパニー |
Bmp−9蛋白
|
AU3968793A
(en)
*
|
1992-04-02 |
1993-11-08 |
United States Of America, As Represented By The Secretary Of Health And Human Services |
Use of restriction endonucleases against viruses, including HIV
|
US6692925B1
(en)
|
1992-11-17 |
2004-02-17 |
Ludwig Institute For Cancer Research |
Proteins having serine/threonine kinase domains, corresponding nucleic acid molecules, and their use
|
WO1994015965A1
(en)
|
1993-01-12 |
1994-07-21 |
Johns Hopkins University School Of Medicine |
Growth differentiation factor-3
|
ATE265529T1
(de)
|
1993-05-12 |
2004-05-15 |
Inst Genetics Llc |
Bmp-10 zusammensetzungen
|
US5637480A
(en)
|
1993-05-12 |
1997-06-10 |
Genetics Institute, Inc. |
DNA molecules encoding bone morphogenetic protein-10
|
US5677196A
(en)
|
1993-05-18 |
1997-10-14 |
University Of Utah Research Foundation |
Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
|
US5831050A
(en)
|
1993-06-07 |
1998-11-03 |
Creative Biomolecules, Inc. |
Morphogen cell surface receptor
|
EP0726948B1
(en)
|
1993-10-14 |
2007-02-28 |
President And Fellows Of Harvard College |
Method of inducing and maintaining neuronal cells
|
US5525490A
(en)
|
1994-03-29 |
1996-06-11 |
Onyx Pharmaceuticals, Inc. |
Reverse two-hybrid method
|
US5658876A
(en)
|
1994-04-28 |
1997-08-19 |
The General Hospital Corporation |
Activin antagonists as novel contraceptives
|
DE69535641D1
(de)
*
|
1994-04-29 |
2007-12-27 |
Curis Inc |
Morphogene protein-spezifische zelloberflächenrezeptoren und ihre verwendungen
|
IL114397A0
(en)
*
|
1994-07-01 |
1995-10-31 |
Bioph Biotech Entw Pharm Gmbh |
Growth/differentiation factor of the TGF-beta-family
|
US5760010A
(en)
|
1995-01-01 |
1998-06-02 |
Klein; Ira |
Method of treating liver disorders with a macrolide antibiotic
|
IL117175A
(en)
*
|
1995-02-20 |
2005-11-20 |
Sankyo Co |
Osteoclastogenesis inhibitory factor protein
|
US5814565A
(en)
|
1995-02-23 |
1998-09-29 |
University Of Utah Research Foundation |
Integrated optic waveguide immunosensor
|
CA2217545A1
(en)
|
1995-04-11 |
1996-10-17 |
Marc Vidal |
Reverse two-hybrid systems
|
EP0771873A3
(en)
*
|
1995-10-27 |
1998-03-04 |
Takeda Chemical Industries, Ltd. |
Neuronal cell-specific receptor protein
|
GB9526131D0
(en)
|
1995-12-21 |
1996-02-21 |
Celltech Therapeutics Ltd |
Recombinant chimeric receptors
|
US20050244867A1
(en)
|
1996-03-26 |
2005-11-03 |
Human Genome Sciences, Inc. |
Growth factor HTTER36
|
US6004780A
(en)
|
1996-03-26 |
1999-12-21 |
Human Genome Sciences, Inc. |
Growth factor HTTER36
|
AU721196B2
(en)
|
1996-10-25 |
2000-06-29 |
G.D. Searle & Co. |
Circularly permuted erythropoietin receptor agonists
|
US6605699B1
(en)
*
|
1997-01-21 |
2003-08-12 |
Human Genome Sciences, Inc. |
Galectin-11 polypeptides
|
US6034062A
(en)
|
1997-03-13 |
2000-03-07 |
Genetics Institute, Inc. |
Bone morphogenetic protein (BMP)-9 compositions and their uses
|
US6231880B1
(en)
|
1997-05-30 |
2001-05-15 |
Susan P. Perrine |
Compositions and administration of compositions for the treatment of blood disorders
|
AU745122B2
(en)
|
1997-07-30 |
2002-03-14 |
Emory University |
Novel bone mineralization proteins, DNA, vectors, expression systems
|
US6656475B1
(en)
|
1997-08-01 |
2003-12-02 |
The Johns Hopkins University School Of Medicine |
Growth differentiation factor receptors, agonists and antagonists thereof, and methods of using same
|
WO1999006559A1
(en)
|
1997-08-01 |
1999-02-11 |
The Johns Hopkins University School Of Medicine |
Methods to identify growth differentiation factor (gdf) receptors
|
US6891082B2
(en)
|
1997-08-01 |
2005-05-10 |
The Johns Hopkins University School Of Medicine |
Transgenic non-human animals expressing a truncated activintype II receptor
|
US6696260B1
(en)
*
|
1997-08-01 |
2004-02-24 |
The Johns Hopkins University School Of Medicine |
Methods to identify growth differentiation factor (GDF) binding proteins
|
WO1999010364A1
(en)
|
1997-08-29 |
1999-03-04 |
Human Genome Sciences, Inc. |
Follistatin-3
|
US6953662B2
(en)
|
1997-08-29 |
2005-10-11 |
Human Genome Sciences, Inc. |
Follistatin-3
|
RU2221809C2
(ru)
|
1997-10-03 |
2004-01-20 |
Тугаи Сейяку Кабусики Кайся |
Способ получения природного гуманизированного антитела
|
US6696411B1
(en)
|
1998-04-22 |
2004-02-24 |
Cornell Research Foundation, Inc. |
Canine erythropoietin gene and recombinant protein
|
WO1999065948A1
(en)
|
1998-06-16 |
1999-12-23 |
Biogen, Inc. |
Variant type ii tgf-beta receptor fusion proteins and methods
|
US6440930B1
(en)
*
|
1998-09-17 |
2002-08-27 |
Eli Lilly And Company |
Protein formulations
|
DE69934995T2
(de)
|
1998-09-22 |
2007-11-22 |
Long Yu |
Für den menschlichen wachstums-differenzierungsfaktor kodierende sequenz und polypeptid, welches durch solche dna-sequenz kodiert wird und verfahren zur herstellung
|
US6472179B2
(en)
*
|
1998-09-25 |
2002-10-29 |
Regeneron Pharmaceuticals, Inc. |
Receptor based antagonists and methods of making and using
|
US6548634B1
(en)
|
1998-09-30 |
2003-04-15 |
Chiron Corporation |
Synthetic peptides having FGF receptor affinity
|
US6238860B1
(en)
|
1998-11-05 |
2001-05-29 |
Dyax Corp. |
Binding moieties for human parvovirus B19
|
US6777205B1
(en)
|
1998-11-06 |
2004-08-17 |
Sterrenbeld Biotechnologie North America, Inc. |
Host cells expressing recombinant human erythropoietin
|
DK1721979T3
(da)
*
|
1998-11-27 |
2010-12-13 |
Ucb Pharma Sa |
Sammensætninger og fremgangsmåder til forøgelse af knoglemineralisering
|
US20040009535A1
(en)
|
1998-11-27 |
2004-01-15 |
Celltech R&D, Inc. |
Compositions and methods for increasing bone mineralization
|
CA2359242C
(en)
|
1999-01-21 |
2009-12-08 |
Metamorphix, Inc. |
Growth differentiation factor inhibitors and uses therefor
|
US6914128B1
(en)
|
1999-03-25 |
2005-07-05 |
Abbott Gmbh & Co. Kg |
Human antibodies that bind human IL-12 and methods for producing
|
EP1174149A1
(en)
|
1999-04-19 |
2002-01-23 |
Kyowa Hakko Kogyo Co., Ltd. |
Proliferation inhibitor for androgen-independent tumor
|
US6468543B1
(en)
|
1999-05-03 |
2002-10-22 |
Zymogenetics, Inc. |
Methods for promoting growth of bone using ZVEGF4
|
WO2001036001A2
(en)
|
1999-11-12 |
2001-05-25 |
Maxygen Holdings Ltd |
Interferon gamma conjugates
|
EP1237565B1
(en)
|
1999-12-15 |
2006-03-08 |
Research Development Foundation |
Betaglycan as an inhibin receptor and uses thereof
|
US20030224501A1
(en)
|
2000-03-17 |
2003-12-04 |
Young Paul E. |
Bone morphogenic protein polynucleotides, polypeptides, and antibodies
|
JP4487376B2
(ja)
|
2000-03-31 |
2010-06-23 |
味の素株式会社 |
腎疾患治療剤
|
BRPI0110914B8
(pt)
|
2000-05-15 |
2021-05-25 |
Hoffmann La Roche |
'composição farmacêutica líquida, processo para preparação da mesma e uso de uma composicão farmacêutica'
|
US6627424B1
(en)
|
2000-05-26 |
2003-09-30 |
Mj Bioworks, Inc. |
Nucleic acid modifying enzymes
|
EP1303605A2
(en)
|
2000-07-19 |
2003-04-23 |
Eli Lilly And Company |
Nucleic acids, vectors, host cells, polypeptides, and uses thereof
|
US6632180B1
(en)
|
2000-09-07 |
2003-10-14 |
John H. Laragh |
Method for evaluating and treating hypertension
|
DE10045591A1
(de)
|
2000-09-15 |
2002-04-04 |
Klaus Pfizenmaier |
Ortsspezifische, antikörpervermittelte Aktivierung proapoptotischer Zytokine - AMAIZe (Antibody-Mediated Apoptosis Inducing Zytokine)
|
EP1356075A4
(en)
|
2000-10-16 |
2005-04-13 |
Compound Therapeutics Inc |
PROTEIN EQUIPMENT FOR ANTIBODY MIMETICS AND OTHER TIE PROTEINS
|
US7087224B2
(en)
|
2000-10-31 |
2006-08-08 |
Amgen Inc. |
Method of treating anemia by administering IL-1ra
|
AU2002225670B2
(en)
|
2000-11-20 |
2006-05-11 |
The Board Of Trustees Of The University Of Illinois |
Membrane scaffold proteins
|
AU2002236558A1
(en)
|
2000-12-01 |
2002-06-11 |
Regents Of The University Of California |
Method and composition for modulating bone growth
|
US20030082233A1
(en)
|
2000-12-01 |
2003-05-01 |
Lyons Karen M. |
Method and composition for modulating bone growth
|
US20030133939A1
(en)
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
TWI329129B
(en)
|
2001-02-08 |
2010-08-21 |
Wyeth Corp |
Modified and stabilized gdf propeptides and uses thereof
|
US20040132971A1
(en)
*
|
2001-02-09 |
2004-07-08 |
Haaning Jesper Mortensen |
Rank ligand-binding polypeptides
|
US20040132675A1
(en)
|
2002-02-08 |
2004-07-08 |
Calvin Kuo |
Method for treating cancer and increasing hematocrit levels
|
US7294472B2
(en)
*
|
2001-03-14 |
2007-11-13 |
Caden Biosciences |
Method for identifying modulators of G protein coupled receptor signaling
|
US20040121008A1
(en)
|
2001-03-16 |
2004-06-24 |
Keiko Shiraishi |
Process for producing sustained release preparation
|
EP1390535B1
(en)
|
2001-04-26 |
2010-06-30 |
Amgen Mountain View Inc. |
Combinatorial libraries of monomer domains
|
DK1436003T3
(da)
|
2001-05-24 |
2010-03-15 |
Zymogenetics Inc |
TACI-immunoglobulin-fusionsproteiner
|
EP1390497A2
(en)
|
2001-05-25 |
2004-02-25 |
Genset |
Human cdnas and proteins and uses thereof
|
AUPR638101A0
(en)
*
|
2001-07-13 |
2001-08-09 |
Bioa Pty Limited |
Composition and method for treatment of disease
|
US6855344B2
(en)
|
2001-07-17 |
2005-02-15 |
Integrated Chinese Medicine Holdings, Ltd. |
Compositions and methods for prostate and kidney health and disorders, an herbal preparation
|
KR100912852B1
(ko)
|
2001-07-17 |
2009-08-18 |
데이진 가부시키가이샤 |
PPAR δ활성화 작용을 측정하는 것을 특징으로 하는물질의 선택방법 및 약제
|
KR100453877B1
(ko)
|
2001-07-26 |
2004-10-20 |
메덱스젠 주식회사 |
연쇄체화에 의한 면역 글로블린 융합 단백질의 제조 방법 및 이 방법에 의해 제조된 TNFR/Fc 융합 단백질, 상기 단백질을 코딩하는 DNA, 상기 DNA를 포함하는벡터, 및 상기 벡터에 의한 형질전환체
|
US7320789B2
(en)
|
2001-09-26 |
2008-01-22 |
Wyeth |
Antibody inhibitors of GDF-8 and uses thereof
|
US6784154B2
(en)
|
2001-11-01 |
2004-08-31 |
University Of Utah Research Foundation |
Method of use of erythropoietin to treat ischemic acute renal failure
|
CN102552261A
(zh)
|
2001-12-06 |
2012-07-11 |
法布罗根股份有限公司 |
提高内源性红细胞生成素(epo)的方法
|
US20030144203A1
(en)
|
2001-12-19 |
2003-07-31 |
Voyager Pharmaceutical Corporation |
Methods for slowing senescence and treating and preventing diseases associated with senescence
|
US20060234918A1
(en)
|
2001-12-19 |
2006-10-19 |
Voyager Pharmaceutical Corporation |
Methods for treating and preventing cancers that express the hypothalamic-pituitary-gonadal axis of hormones and receptors
|
US6998118B2
(en)
|
2001-12-21 |
2006-02-14 |
The Salk Institute For Biological Studies |
Targeted retrograde gene delivery for neuronal protection
|
BR0307548A
(pt)
|
2002-02-11 |
2006-01-17 |
Genentech Inc |
Método de produção de uma variante de anticorpo, variante de anticorpo, composição, ácido nucléico isolado, vetor, célula hospedeira, processo para a produção de uma variante de anticorpo e método de determinação do coeficiente de associação de antìgeno de um anticorpo
|
PL375045A1
(en)
|
2002-02-21 |
2005-11-14 |
Wyeth |
Gasp1: a follistatin domain containing protein
|
US20030219846A1
(en)
|
2002-02-28 |
2003-11-27 |
Pfizer Inc. |
Assay for activity of the ActRIIB kinase
|
WO2003087162A2
(en)
*
|
2002-04-18 |
2003-10-23 |
Mtm Laboratories Ag |
Neopeptides and methods useful for detection and treatment of cancer
|
DE10234192B4
(de)
|
2002-07-26 |
2009-11-26 |
Epoplus Gmbh Co.Kg |
Verwendung von Erythropoetin
|
KR20050083635A
(ko)
|
2002-08-16 |
2005-08-26 |
와이어쓰 |
Bmp-2 에스트로겐 반응 요소 및 이의 사용 방법
|
US7261893B2
(en)
|
2002-10-22 |
2007-08-28 |
Wyeth |
Neutralizing antibodies against GDF-8 and uses therefor
|
US20040223966A1
(en)
|
2002-10-25 |
2004-11-11 |
Wolfman Neil M. |
ActRIIB fusion polypeptides and uses therefor
|
AU2002953327A0
(en)
|
2002-12-12 |
2003-01-09 |
Monash University |
Methods of diagnosing prognosing and treating activin associated diseases and conditions
|
DK1592416T3
(da)
|
2003-02-07 |
2009-04-20 |
Prometic Biosciences Inc |
Fedtsyrer med middel kædelængde, glycerider og analoger som stimulatorer af erythropoiesis
|
US20040197828A1
(en)
|
2003-03-26 |
2004-10-07 |
Gaddy Dana P. |
Method for diagnosis and treatment of bone turnover
|
WO2005028517A2
(en)
*
|
2003-05-09 |
2005-03-31 |
The General Hospital Corporation |
SOLUBLE TGF-β TYPE III RECEPTOR FUSION PROTEINS
|
CN1829532A
(zh)
|
2003-06-02 |
2006-09-06 |
惠氏公司 |
肌肉抑制素(gdf8)抑制剂和皮质类固醇联合用于治疗神经肌肉紊乱的用途
|
NO345763B1
(no)
|
2003-06-16 |
2021-07-19 |
Celltech R&D Inc |
Immunogen og antistoffer spesifikke for sklerostin, samt farmasøytiske preparater for å øke benmineralisering.
|
WO2005009460A2
(en)
|
2003-07-25 |
2005-02-03 |
Medexis, S.A. |
Pharmaceutical composition comprising activin a, alk-4 or derivatives thereof for the treatment of ophthalmic disorders or cancer
|
US8895540B2
(en)
|
2003-11-26 |
2014-11-25 |
DePuy Synthes Products, LLC |
Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
|
PT1706428E
(pt)
*
|
2004-01-22 |
2009-12-29 |
Merck Patent Gmbh |
Anticorpos anticancerígenos com fixação de complemento reduzida
|
US20050197292A1
(en)
*
|
2004-01-30 |
2005-09-08 |
Glennda Smithson |
Compositions and methods for treating T-cell mediated pathological conditions
|
JP2007530055A
(ja)
*
|
2004-03-26 |
2007-11-01 |
アクセルロン ファーマ インコーポレーテッド |
Bmp−3プロペプチドおよび関連する方法
|
EP1730186A2
(en)
*
|
2004-03-31 |
2006-12-13 |
Xencor, Inc. |
Bmp-7 variants with improved properties
|
US7741284B2
(en)
|
2004-05-12 |
2010-06-22 |
Acceleron Pharma Inc. |
BMP10 propeptides and related methods
|
AU2005258286A1
(en)
|
2004-06-24 |
2006-01-05 |
Acceleron Pharma Inc. |
GDF3 propeptides and related methods
|
EP3489257A1
(en)
|
2004-07-23 |
2019-05-29 |
Acceleron Pharma Inc. |
Actrii receptor polypeptides, methods and compositions
|
EP1794191B1
(en)
|
2004-08-05 |
2016-05-18 |
The Regents of The University of California |
Molecules with effects on cellular development and function
|
JP2008509927A
(ja)
|
2004-08-12 |
2008-04-03 |
ワイス |
Gdf−8阻害剤を使用する、糖尿病、肥満、および心臓血管疾患のための併用療法
|
EP1804824B1
(en)
|
2004-09-29 |
2017-01-04 |
Icahn School of Medicine at Mount Sinai |
Fsh and fsh receptor modulator compositions and methods for inhibiting osteoclastic bone resorption and bone loss in osteoporosis
|
JP2008520207A
(ja)
|
2004-11-16 |
2008-06-19 |
アヴィディア リサーチ インスティテュート |
タンパク質骨格およびその使用
|
NL1027887C2
(nl)
|
2004-12-24 |
2006-06-27 |
Bosch Gmbh Robert |
Transmissie met gebombeerde poelieschijven en een drijfriem.
|
NZ538097A
(en)
|
2005-02-07 |
2006-07-28 |
Ovita Ltd |
Method and compositions for improving wound healing
|
EP2335719B1
(en)
|
2005-02-16 |
2015-06-24 |
The General Hospital Corporation |
Use of hemojuvelin fusion proteins to regulate hepcidin-mediated iron metabolism
|
AU2006239860B2
(en)
|
2005-04-25 |
2012-01-19 |
Amgen Fremont Inc. |
Antibodies to myostatin
|
JPWO2006115274A1
(ja)
|
2005-04-26 |
2008-12-18 |
味の素株式会社 |
骨髄赤血球前駆細胞分化促進剤
|
JP2007099764A
(ja)
|
2005-09-09 |
2007-04-19 |
Ajinomoto Co Inc |
血糖低下剤
|
EA015351B1
(ru)
|
2005-09-28 |
2011-06-30 |
Займодженетикс, Инк. |
Антагонисты il-17a и il-17f и способы их применения
|
US8067562B2
(en)
|
2005-11-01 |
2011-11-29 |
Amgen Inc. |
Isolated nucleic acid molecule comprising the amino acid sequence of SEQ ID NO:1
|
EP1973559B1
(en)
|
2005-11-23 |
2013-01-09 |
Acceleron Pharma Inc. |
Activin-actriia antagonists and uses for promoting bone growth
|
US8128933B2
(en)
|
2005-11-23 |
2012-03-06 |
Acceleron Pharma, Inc. |
Method of promoting bone growth by an anti-activin B antibody
|
JP2009518422A
(ja)
|
2005-12-06 |
2009-05-07 |
アムジェン インコーポレイテッド |
ミオスタチン・アンタゴニストの使用
|
CA2632936A1
(en)
|
2005-12-20 |
2007-06-28 |
Merck Frosst Canada Ltd. |
Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
|
JP2009521452A
(ja)
|
2005-12-21 |
2009-06-04 |
シェーリング コーポレイション |
コレステロール降下剤およびh3受容体アンタゴニスト/逆アゴニストを使用する非アルコール性脂肪性肝疾患の処置
|
WO2007076127A2
(en)
|
2005-12-22 |
2007-07-05 |
Biogen Idec Ma Inc |
Condensed imidazoles or pyrazoles and their use as transforming growth factor modulators
|
JP4925364B2
(ja)
|
2006-01-20 |
2012-04-25 |
ベックマン コールター, インコーポレイテッド |
鉄欠乏を検出する方法
|
CA2637375A1
(en)
|
2006-01-25 |
2007-08-02 |
Wellstat Therapeutics Corporation |
Compounds for the treatment of metabolic disorders
|
EP1988772B1
(en)
|
2006-02-28 |
2011-10-26 |
Wellstat Therapeutics Corporation |
Compounds for the treatment of metabolic disorders
|
EP2007813A2
(en)
|
2006-04-14 |
2008-12-31 |
Amgen Inc. |
Agonist erythropoietin receptor antibodies
|
WO2007123391A1
(en)
|
2006-04-20 |
2007-11-01 |
Academisch Ziekenhuis Leiden |
Therapeutic intervention in a genetic disease in an individual by modifying expression of an aberrantly expressed gene.
|
EP2023913A2
(en)
|
2006-05-09 |
2009-02-18 |
Colorado State University Research Foundation |
Methods for treating blood disorders
|
TW200803123A
(en)
*
|
2006-06-02 |
2008-01-01 |
Delta Electronics Inc |
Power converter and magnetic structure thereof
|
JP5335674B2
(ja)
|
2006-07-21 |
2013-11-06 |
ライン ラボラトリーズ |
酢酸カルシウムの液体組成物
|
GB0615129D0
(en)
|
2006-07-29 |
2006-09-06 |
Univ Cardiff |
Anti-cancer activity of BMP-9 and BMP-10 and their use in cancer therapies
|
CL2007002567A1
(es)
|
2006-09-08 |
2008-02-01 |
Amgen Inc |
Proteinas aisladas de enlace a activina a humana.
|
US7547781B2
(en)
|
2006-09-11 |
2009-06-16 |
Curis, Inc. |
Quinazoline based EGFR inhibitors containing a zinc binding moiety
|
WO2008060139A1
(en)
|
2006-11-17 |
2008-05-22 |
Erasmus University Medical Center Rotterdam |
Methods for controlling mineralization of extracellular matrix, therapeutic methods based thereon and medicaments for use therein
|
WO2008073292A2
(en)
|
2006-12-08 |
2008-06-19 |
Caritas St. Elizabeth's Medical Center Of Boston, Inc. |
Method for protecting renal tubular epithelial cells from radiocontrast nephro parhy (rcn)
|
CA2672581A1
(en)
|
2006-12-14 |
2008-06-19 |
Forerunner Pharma Research Co., Ltd. |
Anti-claudin 3 monoclonal antibody and treatment and diagnosis of cancer using the same
|
PL2468290T3
(pl)
|
2006-12-18 |
2015-08-31 |
Acceleron Pharma Inc |
Antagoniści aktywiny-ActRII do stosowania w leczeniu niedokrwistości
|
US20100028332A1
(en)
|
2006-12-18 |
2010-02-04 |
Acceleron Pharma Inc. |
Antagonists of actriib and uses for increasing red blood cell levels
|
US8895016B2
(en)
|
2006-12-18 |
2014-11-25 |
Acceleron Pharma, Inc. |
Antagonists of activin-actriia and uses for increasing red blood cell levels
|
RU2473362C2
(ru)
*
|
2007-02-01 |
2013-01-27 |
Акселерон Фарма Инк. |
АНТАГОНИСТЫ АКТИВИНА-ActRIIa-Fc И ИХ ПРИМЕНЕНИЕ ДЛЯ ЛЕЧЕНИЯ ИЛИ ПРОФИЛАКТИКИ РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ
|
TW201940502A
(zh)
|
2007-02-02 |
2019-10-16 |
美商艾瑟勒朗法瑪公司 |
衍生自ActRIIB的變體與其用途
|
EP2120999B1
(en)
*
|
2007-02-09 |
2012-08-29 |
Acceleron Pharma, Inc. |
Pharmaceutical compositions comprising Activin-ActRIIA antagonists and use thereof in preventing or treating multiple myeloma
|
TW201718635A
(zh)
|
2007-03-06 |
2017-06-01 |
安美基公司 |
變異之活動素受體多肽及其用途
|
US8501678B2
(en)
|
2007-03-06 |
2013-08-06 |
Atara Biotherapeutics, Inc. |
Variant activin receptor polypeptides and uses thereof
|
EP2150560A1
(en)
|
2007-06-01 |
2010-02-10 |
Wyeth |
Methods and compositions for modulating bmp-10 activity
|
WO2009009059A1
(en)
|
2007-07-09 |
2009-01-15 |
Biogen Idec Ma Inc. |
Spiro compounds as antagonists of tgf-beta
|
US20090025308A1
(en)
*
|
2007-07-26 |
2009-01-29 |
Deans Brian W |
Seismic support and reinforcement systems
|
GB0715087D0
(en)
|
2007-08-03 |
2007-09-12 |
Summit Corp Plc |
Drug combinations for the treatment of duchenne muscular dystrophy
|
HUE033195T2
(en)
|
2007-08-03 |
2017-11-28 |
Summit (Oxford) Ltd |
Combinations of drugs for the treatment of Duchenne muscular dystrophy
|
GB0715938D0
(en)
|
2007-08-15 |
2007-09-26 |
Vastox Plc |
Method of treatment of duchenne muscular dystrophy
|
WO2009025651A1
(en)
|
2007-08-17 |
2009-02-26 |
University Of Maine System Board Of Trustees |
Biologically active peptide and method of using the same
|
US20100279409A1
(en)
|
2007-09-13 |
2010-11-04 |
Neil Robson |
Method for modifying celluar immune resonse by modulating activin activity
|
WO2009038745A1
(en)
*
|
2007-09-18 |
2009-03-26 |
Acceleron Pharma Inc. |
Activin-actriia antagonists and uses for decreasing or inhibiting fsh secretion
|
PE20091163A1
(es)
|
2007-11-01 |
2009-08-09 |
Wyeth Corp |
Anticuerpos para gdf8
|
CA2705879A1
(en)
|
2007-11-21 |
2009-06-04 |
Amgen Inc. |
Wise binding agents and epitopes
|
CA2718403A1
(en)
|
2008-03-13 |
2009-09-17 |
The General Hospital Corporation |
Inhibitors of the bmp signaling pathway
|
CA2725208A1
(en)
|
2008-05-06 |
2009-11-12 |
Joslin Diabetes Center, Inc. |
Methods and compositions for inducing brown adipogenesis
|
WO2009137075A1
(en)
*
|
2008-05-06 |
2009-11-12 |
Acceleron Pharma Inc. |
Anti-activin antibodies and uses for promoting bone growth
|
KR20220002710A
(ko)
|
2008-06-26 |
2022-01-06 |
악셀레론 파마 인코포레이티드 |
액티빈-actriia 길항물질을 투약하는 방법 및 치료된 환자의 모니터링
|
NZ602471A
(en)
|
2008-06-26 |
2014-10-31 |
Acceleron Pharma Inc |
Antagonists of activin-actriia and uses for increasing red blood cell levels
|
DK3494986T3
(da)
|
2008-08-14 |
2020-08-03 |
Acceleron Pharma Inc |
GDF fanger
|
US8216997B2
(en)
|
2008-08-14 |
2012-07-10 |
Acceleron Pharma, Inc. |
Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
|
US20110293526A1
(en)
|
2008-11-20 |
2011-12-01 |
University Of Southern California |
Compositions and methods to modulate hair growth
|
NZ604818A
(en)
|
2008-11-26 |
2014-07-25 |
Amgen Inc |
Variants of activin iib receptor polypeptides and uses thereof
|
AU2010204985A1
(en)
|
2009-01-13 |
2011-08-04 |
Acceleron Pharma Inc. |
Methods for increasing adiponectin
|
US8110355B2
(en)
|
2009-02-20 |
2012-02-07 |
GenRemedy, LLC |
Methods for identifying agents that inhibit cell migration, promote cell adhesion and prevent metastasis
|
ES2655877T3
(es)
|
2009-04-27 |
2018-02-22 |
Novartis Ag |
Composiciones y métodos para aumentar el crecimiento muscular
|
MX2011013172A
(es)
|
2009-06-08 |
2012-04-02 |
Acceleron Pharma Inc |
Metodos para aumentar adipocitos termogenicos.
|
EP3805259A1
(en)
|
2009-06-12 |
2021-04-14 |
Acceleron Pharma Inc. |
Truncated actriib-fc fusion proteins
|
CN113577291A
(zh)
|
2009-08-13 |
2021-11-02 |
阿塞勒隆制药公司 |
Gdf捕获物和促红细胞生成素受体激活剂联合应用以增加红细胞水平
|
CN102781518A
(zh)
|
2009-09-09 |
2012-11-14 |
阿塞勒隆制药公司 |
Actriib拮抗剂及其给药和用途
|
EP2496247B1
(en)
|
2009-11-03 |
2017-08-23 |
Acceleron Pharma, Inc. |
Methods for treating fatty liver disease
|
CA2781152A1
(en)
|
2009-11-17 |
2011-05-26 |
Acceleron Pharma Inc. |
Actriib proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy
|
WO2012027065A2
(en)
|
2010-08-27 |
2012-03-01 |
Celgene Corporation |
Combination therapy for treatment of disease
|
US8580922B2
(en)
|
2011-03-04 |
2013-11-12 |
Shire Human Genetic Therapies, Inc. |
Peptide linkers for polypeptide compositions and methods for using same
|
US9365651B2
(en)
|
2011-07-01 |
2016-06-14 |
Novartis Ag |
Method for treating metabolic disorders by administration of an anti-ActRIIB antibody
|
EP3520805B1
(en)
|
2011-10-17 |
2021-03-10 |
Acceleron Pharma Inc. |
Compositions for treating myelofibrosis
|
US8765385B2
(en)
|
2011-10-27 |
2014-07-01 |
Ravindra Kumar |
Method of detection of neutralizing anti-actriib antibodies
|
WO2013063536A1
(en)
|
2011-10-27 |
2013-05-02 |
Acceleron Pharma, Inc. |
Actriib binding agents and uses thereof
|
US20140303068A1
(en)
|
2011-10-28 |
2014-10-09 |
Paranta Biosciences Limited |
Method of treating mucus hypersecretion
|
KR20140108562A
(ko)
|
2011-12-19 |
2014-09-11 |
암젠 인코퍼레이티드 |
변이체 액티빈 수용체 폴리펩티드 단독 또는 화학 치료법과의 결합, 및 그들의 용도
|
US9254311B2
(en)
|
2012-04-02 |
2016-02-09 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of proteins
|
EP3521310A1
(en)
|
2012-06-14 |
2019-08-07 |
The Medical Research, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center |
Use of blocking agents of bone morphogenic protein (bmp) signaling for the treatment of neuroinflammatory and neurodegenerative diseases
|
WO2014007198A1
(ja)
|
2012-07-02 |
2014-01-09 |
協和発酵キリン株式会社 |
抗bmp9抗体を有効成分とする、腎性貧血、がん性貧血などの貧血に対する治療剤
|
CN104981250A
(zh)
|
2012-10-24 |
2015-10-14 |
细胞基因公司 |
用于治疗贫血的方法
|
EP3608419A1
(en)
|
2012-10-24 |
2020-02-12 |
Celgene Corporation |
Biomarker for use in treating anemia
|
WO2014064292A1
(en)
|
2012-10-26 |
2014-05-01 |
Universite Pierre Et Marie Curie (Paris 6) |
A method for preventing or treating atrial fibrillation
|
NZ707477A
(en)
|
2012-11-02 |
2019-09-27 |
Celgene Corp |
Activin-actrii antagonists and uses for treating bone and other disorders
|
CA3240136A1
(en)
|
2012-11-08 |
2014-05-15 |
Clearside Biomedical, Inc. |
Methods and devices for the treatment of ocular diseases in human subjects
|
US20150328249A1
(en)
|
2012-12-11 |
2015-11-19 |
Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center |
Modulation of myofiber repair by anti-myostatin strategies and/or ppar gamma ligands, alone or in combination with stem cells, for the therapy of critical limb ischemia and other ischemic processes affecting the skeletal muscle
|
US20140220033A1
(en)
|
2013-02-01 |
2014-08-07 |
Santa Maria Biotherapeutics, Inc. |
Administration of an Anti-Activin-A Compound to a Subject
|
EP3431592A1
(en)
|
2013-03-14 |
2019-01-23 |
Translate Bio, Inc. |
Mrna therapeutic compositions and use to treat diseases and disorders
|
TWI655207B
(zh)
|
2013-07-30 |
2019-04-01 |
再生元醫藥公司 |
抗活化素a之抗體及其用途
|
SG10201801063TA
(en)
|
2013-08-14 |
2018-04-27 |
Novartis Ag |
Methods of treating sporadic inclusion body myositis
|
US20160313349A1
(en)
|
2013-12-16 |
2016-10-27 |
Paranta Biosciences Limited |
Method of diagnosis and treatment
|
WO2015108972A1
(en)
|
2014-01-14 |
2015-07-23 |
Santa Maria Biotherapeutics, Inc. |
Activin inhibitor response prediction and uses for treatment
|
US20170248609A1
(en)
|
2014-01-27 |
2017-08-31 |
Novartis Ag |
Biomarkers predictive of muscle atrophy, method and use
|
JP6601687B2
(ja)
|
2014-03-31 |
2019-11-06 |
大日本住友製薬株式会社 |
進行性骨化性線維異形成症の予防剤及び治療剤
|
MA52909A
(fr)
|
2014-04-18 |
2021-04-21 |
Acceleron Pharma Inc |
Procédés d'augmentation des taux de globules rouges et de traitement de la drépanocytose
|
TW201622746A
(zh)
|
2014-04-24 |
2016-07-01 |
諾華公司 |
改善或加速髖部骨折術後身體復原之方法
|
WO2015187977A1
(en)
|
2014-06-04 |
2015-12-10 |
Acceleron Pharma, Inc. |
Methods and compositions for treatment of disorders with follistatin polypeptides
|
KR20170035891A
(ko)
|
2014-06-13 |
2017-03-31 |
산타 마리아 바이오테라퓨틱스, 인코포레이티드 |
제형화된 수용체 폴리펩타이드 및 관련 방법
|
IL284686B2
(en)
|
2015-05-13 |
2023-05-01 |
Celgene Corp |
Treatment of beta-thalassemia using actrii ligand traps
|