HK1106778A1 - Tripeptide and tetrapeptide sulfones - Google Patents

Tripeptide and tetrapeptide sulfones

Info

Publication number
HK1106778A1
HK1106778A1 HK07114049A HK07114049A HK1106778A1 HK 1106778 A1 HK1106778 A1 HK 1106778A1 HK 07114049 A HK07114049 A HK 07114049A HK 07114049 A HK07114049 A HK 07114049A HK 1106778 A1 HK1106778 A1 HK 1106778A1
Authority
HK
Hong Kong
Prior art keywords
tripeptide
tetrapeptide
sulfones
tetrapeptide sulfones
Prior art date
Application number
HK07114049A
Other languages
English (en)
Inventor
Steven R Schow
Natalia Aurrecoechea
Original Assignee
Telik Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Telik Inc filed Critical Telik Inc
Publication of HK1106778A1 publication Critical patent/HK1106778A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK07114049A 2005-01-06 2007-12-21 Tripeptide and tetrapeptide sulfones HK1106778A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64193205P 2005-01-06 2005-01-06
PCT/US2006/000532 WO2006074409A1 (en) 2005-01-06 2006-01-05 Tripeptide and tetrapeptide sulfones

Publications (1)

Publication Number Publication Date
HK1106778A1 true HK1106778A1 (en) 2008-03-20

Family

ID=36123437

Family Applications (2)

Application Number Title Priority Date Filing Date
HK07114049A HK1106778A1 (en) 2005-01-06 2007-12-21 Tripeptide and tetrapeptide sulfones
HK07114048A HK1106796A1 (en) 2005-01-06 2007-12-21 Tripeptide and tetrapeptide thioethers

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK07114048A HK1106796A1 (en) 2005-01-06 2007-12-21 Tripeptide and tetrapeptide thioethers

Country Status (25)

Country Link
US (2) US7129215B2 (pl)
EP (2) EP1833978B1 (pl)
JP (2) JP4903716B2 (pl)
KR (2) KR101244609B1 (pl)
CN (2) CN101090977B (pl)
AR (2) AR051889A1 (pl)
AT (2) ATE410520T1 (pl)
AU (2) AU2006204022B2 (pl)
BR (2) BRPI0606520A2 (pl)
CA (2) CA2587284C (pl)
DE (2) DE602006003064D1 (pl)
DK (2) DK1833978T3 (pl)
EA (2) EA200701398A1 (pl)
ES (2) ES2314890T3 (pl)
HK (2) HK1106778A1 (pl)
HR (2) HRP20090128T3 (pl)
IL (2) IL182836A (pl)
MX (2) MX2007008255A (pl)
NZ (2) NZ555362A (pl)
PL (2) PL1833978T3 (pl)
PT (2) PT1833978E (pl)
SI (2) SI1833978T1 (pl)
TW (2) TWI317739B (pl)
WO (2) WO2006074249A1 (pl)
ZA (2) ZA200704487B (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8198247B2 (en) * 2004-12-21 2012-06-12 Telik, Inc. Process for and intermediates in the preparation of canfosfamide and its salts
KR101244609B1 (ko) * 2005-01-06 2013-03-25 텔리크 인코포레이티드 트리펩티드 및 테트라펩티드 티오에테르
US20070154963A1 (en) * 2005-12-30 2007-07-05 Danying Cai Method to determine whether a compound is a cellular GSTpi inhibitor
US20090238763A1 (en) 2006-07-09 2009-09-24 Chongxi Yu High penetration compositions and uses thereof
US20090221703A1 (en) 2006-07-09 2009-09-03 Chongxi Yu High penetration composition and uses thereof
AU2016213759B2 (en) * 2006-11-08 2018-03-29 Chongxi Yu Transdermal delivery systems of peptides and related compounds
JP5424887B2 (ja) * 2006-11-08 2014-02-26 チョンシー ユー ペプチド及び関連化合物の経皮送達システム
WO2008149181A1 (en) 2007-06-04 2008-12-11 Techfields Inc Pro-drugs of nsaias with very high skin and membranes penetration rates and their new medicinal uses
WO2010065936A1 (en) 2008-12-04 2010-06-10 Chongxi Yu High penetration compositions and their applications
DE102008060888A1 (de) 2008-12-09 2010-06-10 Evonik Stockhausen Gmbh Verfahren zur Herstellung von Acrolein umfassend die Aufarbeitung einer Rohglycerin-Phase
DK2427475T3 (da) 2009-05-08 2021-02-01 Techfields Biochem Co Ltd Prodrug-sammensætninger med høj gennemtrængelighed af peptider og peptid-relaterede forbindelser
JP2013528214A (ja) 2010-06-07 2013-07-08 テリック，インコーポレイテッド 結晶性エザチオスタット塩酸塩非溶媒和物ｄ型の調製
CN102917694A (zh) * 2010-06-07 2013-02-06 泰立克公司 依泽替米贝的片剂制剂
US20130035389A1 (en) * 2011-08-05 2013-02-07 Telik, Inc. Methods for treating myelodysplastic syndrome with ezatiostat
JP5970439B2 (ja) * 2013-09-20 2016-08-17 チョンシー ユー ペプチド及び関連化合物の経皮送達システム
CN106146616A (zh) * 2015-04-03 2016-11-23 浙江海正药业股份有限公司 环肽类化合物及其制备和用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5599903A (en) * 1992-04-03 1997-02-04 Terrapin Technologies, Inc. Glutathione analogs and paralog panels comprising glutathione mimics
US5786336A (en) * 1991-04-29 1998-07-28 Terrapin Technologies, Inc. Target-selective protocols based on mimics
US5556942A (en) 1991-04-29 1996-09-17 Terrapin Technologies, Inc. Glutathione S-transferase-activated compounds
US5767086A (en) * 1992-04-03 1998-06-16 Terrapin Technologies, Inc. Bone marrow stimulation by certain glutathione analogs
US5955432A (en) * 1992-04-03 1999-09-21 Terrapin Technologies, Inc. Metabolic effects of certain glutathione analogs
CA2105492C (en) * 1993-09-03 2000-02-01 Lawrence M. Kauvar Glutathione analogs and paralog panels comprising glutathione mimics
US5908919A (en) * 1993-10-01 1999-06-01 Terrapin Technologies Urethane mediated, GST specific molecular release systems
ATE280582T1 (de) * 1995-06-07 2004-11-15 Telik Inc Stoffwechseleffekt von bestimmten glutation analogen
AU4124697A (en) 1996-09-02 1998-03-26 Manchester Metropolitan University, The S-blocked glutathiones
CA2328731A1 (en) * 1998-04-16 1999-10-28 Atsushi Imaizumi Glutathione derivatives and dosage forms thereof
ATE286741T1 (de) * 1999-01-27 2005-01-15 Telik Inc Glutathioneanaloge enthaltende therapeutische zusammensetzungen
US7029695B2 (en) * 2001-07-10 2006-04-18 Telik, Inc. Therapeutic compositions containing glutathione analogs
TWI323662B (en) * 2002-11-15 2010-04-21 Telik Inc Combination cancer therapy with a gst-activated anticancer compound and another anticancer therapy
KR101244609B1 (ko) * 2005-01-06 2013-03-25 텔리크 인코포레이티드 트리펩티드 및 테트라펩티드 티오에테르

Also Published As

Publication number Publication date
ES2314891T3 (es) 2009-03-16
PT1833978E (pt) 2008-12-02
AR051890A1 (es) 2007-02-14
EP1833978B1 (en) 2008-10-08
EP1833842B1 (en) 2008-10-08
KR20070091611A (ko) 2007-09-11
TW200635949A (en) 2006-10-16
BRPI0606520A2 (pt) 2009-06-30
JP2008526859A (ja) 2008-07-24
NZ555361A (en) 2009-05-31
DE602006003063D1 (de) 2008-11-20
AR051889A1 (es) 2007-02-14
EA200701399A1 (ru) 2008-02-28
PL1833978T3 (pl) 2009-04-30
DK1833978T3 (da) 2009-02-09
AU2006204022A1 (en) 2006-07-13
DK1833842T3 (da) 2009-02-09
US7129215B2 (en) 2006-10-31
JP4903717B2 (ja) 2012-03-28
US20060160749A1 (en) 2006-07-20
KR20070104391A (ko) 2007-10-25
ATE410440T1 (de) 2008-10-15
HRP20090134T3 (en) 2009-04-30
EP1833842A1 (en) 2007-09-19
CN101090977A (zh) 2007-12-19
HRP20090128T3 (en) 2009-04-30
WO2006074409A9 (en) 2006-12-14
SI1833978T1 (sl) 2009-04-30
ES2314890T3 (es) 2009-03-16
TWI317739B (en) 2009-12-01
MX2007008254A (es) 2007-09-11
PT1833842E (pt) 2008-12-11
EA200701398A1 (ru) 2007-12-28
IL182836A (en) 2010-11-30
KR101244609B1 (ko) 2013-03-25
DE602006003064D1 (en) 2008-11-20
HK1106796A1 (en) 2008-03-20
ZA200704487B (en) 2008-09-25
US7192918B2 (en) 2007-03-20
PL1833842T3 (pl) 2009-04-30
CA2587310A1 (en) 2006-07-13
ZA200704488B (en) 2008-09-25
IL182836A0 (en) 2007-08-19
ATE410520T1 (de) 2008-10-15
AU2006203901B2 (en) 2011-06-02
AU2006203901A1 (en) 2006-07-13
AU2006204022B2 (en) 2011-01-20
IL183107A (en) 2010-11-30
TWI317738B (en) 2009-12-01
BRPI0606396A2 (pt) 2009-06-23
EP1833978A1 (en) 2007-09-19
CA2587310C (en) 2013-11-12
CN101090977B (zh) 2013-04-10
WO2006074249A1 (en) 2006-07-13
US20060148719A1 (en) 2006-07-06
TW200635948A (en) 2006-10-16
WO2006074409A1 (en) 2006-07-13
SI1833842T1 (sl) 2009-04-30
CA2587284C (en) 2014-03-25
JP4903716B2 (ja) 2012-03-28
MX2007008255A (es) 2007-09-11
NZ555362A (en) 2009-05-31
IL183107A0 (en) 2007-09-20
JP2008526880A (ja) 2008-07-24
CA2587284A1 (en) 2006-07-13
CN101080418A (zh) 2007-11-28

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130105