HK1102808A1 - (r/s) rifamycin derivatives, their preparation and pharmaceutical compositions - Google Patents
(r/s) rifamycin derivatives, their preparation and pharmaceutical compositionsInfo
- Publication number
- HK1102808A1 HK1102808A1 HK07110800.2A HK07110800A HK1102808A1 HK 1102808 A1 HK1102808 A1 HK 1102808A1 HK 07110800 A HK07110800 A HK 07110800A HK 1102808 A1 HK1102808 A1 HK 1102808A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- sub
- rifamycin derivatives
- preparation
- humans
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/02—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing not further condensed quinolizine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59019004P | 2004-07-22 | 2004-07-22 | |
PCT/US2005/025924 WO2006012443A1 (en) | 2004-07-22 | 2005-07-21 | (r/s) rifamycin derivatives, their preparation and pharmaceutical compositions |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1102808A1 true HK1102808A1 (en) | 2007-12-07 |
Family
ID=35355764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK07110800.2A HK1102808A1 (en) | 2004-07-22 | 2007-10-04 | (r/s) rifamycin derivatives, their preparation and pharmaceutical compositions |
Country Status (11)
Country | Link |
---|---|
US (2) | US7226931B2 (xx) |
EP (2) | EP1768987B1 (xx) |
JP (2) | JP5153329B2 (xx) |
CN (2) | CN101031572B (xx) |
AT (1) | ATE427311T1 (xx) |
AU (1) | AU2005267054B2 (xx) |
CA (2) | CA2574301C (xx) |
DE (1) | DE602005013671D1 (xx) |
HK (1) | HK1102808A1 (xx) |
NZ (1) | NZ565002A (xx) |
WO (2) | WO2006012443A1 (xx) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6544555B2 (en) * | 2000-02-24 | 2003-04-08 | Advancis Pharmaceutical Corp. | Antibiotic product, use and formulation thereof |
US6541014B2 (en) * | 2000-10-13 | 2003-04-01 | Advancis Pharmaceutical Corp. | Antiviral product, use and formulation thereof |
US20020068078A1 (en) * | 2000-10-13 | 2002-06-06 | Rudnic Edward M. | Antifungal product, use and formulation thereof |
US20020197314A1 (en) * | 2001-02-23 | 2002-12-26 | Rudnic Edward M. | Anti-fungal composition |
JP2006528185A (ja) * | 2003-07-21 | 2006-12-14 | アドバンシス ファーマスーティカル コーポレイション | 抗生物質製剤、その使用法及び作成方法 |
JP2006528189A (ja) * | 2003-07-21 | 2006-12-14 | アドバンシス ファーマスーティカル コーポレイション | 抗生物質産物、その使用法および製剤 |
JP2006528190A (ja) * | 2003-07-21 | 2006-12-14 | アドバンシス ファーマスーティカル コーポレイション | 抗生物質製剤、その使用法及び作成方法 |
WO2005016311A1 (en) | 2003-08-11 | 2005-02-24 | Advancis Pharmaceutical Corporation | Robust pellet |
CA2535398C (en) | 2003-08-12 | 2013-11-12 | Advancis Pharmaceuticals Corporation | Antibiotic product, use and formulation thereof |
CA2535780A1 (en) * | 2003-08-29 | 2005-03-17 | Advancis Pharmaceuticals Corporation | Antibiotic product, use and formulation thereof |
JP2007513869A (ja) * | 2003-09-15 | 2007-05-31 | アドバンシス ファーマスーティカル コーポレイション | 抗生物質製剤、その使用法及び作成方法 |
WO2005056526A1 (ja) | 2003-12-12 | 2005-06-23 | Daiichi Pharmaceutical Co., Ltd. | 光学活性なシクロプロピルアミン誘導体の製造中間体およびその製造法 |
JP2008505124A (ja) * | 2004-07-02 | 2008-02-21 | アドバンシス ファーマスーティカル コーポレイション | パルス送達用錠剤 |
GB0505909D0 (en) * | 2005-03-23 | 2005-04-27 | Univ Leeds | Formulations |
EA016059B1 (ru) | 2005-08-11 | 2012-01-30 | Тарганта Терапьютикс Инк. | Фосфонированные рифамицины и их применение для профилактики и лечения костных и суставных инфекций |
WO2007021683A2 (en) | 2005-08-15 | 2007-02-22 | Janssen Pharmaceutica N.V. | Human cell clones useful for functional analyses of the biological activity of an endogeneous urotensin ii receptor and uses thereof |
US8778924B2 (en) * | 2006-12-04 | 2014-07-15 | Shionogi Inc. | Modified release amoxicillin products |
US8357394B2 (en) | 2005-12-08 | 2013-01-22 | Shionogi Inc. | Compositions and methods for improved efficacy of penicillin-type antibiotics |
US8299052B2 (en) * | 2006-05-05 | 2012-10-30 | Shionogi Inc. | Pharmaceutical compositions and methods for improved bacterial eradication |
TWI454262B (zh) | 2006-11-02 | 2014-10-01 | Targacept Inc | 菸鹼乙醯膽鹼受體亞型選擇性之二氮雜雙環烷類醯胺 |
WO2009064792A1 (en) * | 2007-11-16 | 2009-05-22 | Cumbre Pharmaceuticals Inc. | Quinolone carboxylic acid-substituted rifamycin derivatives |
CN104650114A (zh) | 2008-02-25 | 2015-05-27 | 萨利克斯药品有限公司 | 利福昔明的多种形式及其用途 |
US8486956B2 (en) * | 2008-02-25 | 2013-07-16 | Salix Pharmaceuticals, Ltd | Forms of rifaximin and uses thereof |
EP2257549A1 (en) * | 2008-03-05 | 2010-12-08 | Targacept Inc. | Nicotinic acetylcholine receptor sub-type selective amides of diazabicycloal kanes |
US8278313B2 (en) * | 2008-03-11 | 2012-10-02 | Abbott Laboratories | Macrocyclic spiro pyrimidine derivatives |
WO2010019511A2 (en) | 2008-08-13 | 2010-02-18 | Targanta Therapeutics Corp. | Phosphonated rifamycins and uses thereof for the prevention and treatment of bone and joint infections |
CN101875658B (zh) * | 2009-04-28 | 2013-01-09 | 上海药明康德新药开发有限公司 | 3-羰基-2,8-二氮杂螺[4.5] 癸烷-8-羧酸叔丁酯的制备方法 |
AU2010310595B2 (en) | 2009-10-23 | 2015-07-16 | Janssen Pharmaceutica Nv | Disubstituted octahy - dropyrrolo [3,4-c] pyrroles as orexin receptor modulators |
CA2801074A1 (en) | 2010-06-04 | 2011-12-08 | Albany Molecular Research, Inc. | Glycine transporter-1 inhibitors, methods of making them, and uses thereof |
MX2015001963A (es) * | 2012-08-13 | 2015-06-04 | Adipharm Ead | Formulaciones farmaceuticas que contienen derivados con 3-(4-cinamil-1-piperazinil)-amino de 3-formilrifamicinas sv y 3-formilrifamicina s y un proceso para su preparacion. |
CN104955457A (zh) * | 2012-09-12 | 2015-09-30 | 萨利克斯药品公司 | 给予利福昔明而不产生抗生素耐药性的方法 |
CN103709177B (zh) * | 2013-12-20 | 2016-02-24 | 武汉工程大学 | 利福霉素类沃尼妙林杂合抗生素及其制备方法 |
CN104710439B (zh) * | 2015-03-06 | 2017-11-07 | 丹诺医药(苏州)有限公司 | 一种利福霉素‑喹嗪酮双靶标分子的晶型i及其制备方法 |
CN104628745B (zh) * | 2015-03-06 | 2017-03-08 | 丹诺医药(苏州)有限公司 | 一种利福霉素‑喹嗪酮双靶标分子的富马酸盐及其制备方法 |
HUE058759T2 (hu) | 2016-03-10 | 2022-09-28 | Janssen Pharmaceutica Nv | Módszerek depresszió kezelésére orexin-2 receptor antagonisták alkalmazásával |
CN105879009A (zh) * | 2016-04-18 | 2016-08-24 | 丹诺医药(苏州)有限公司 | 一种用于治疗革兰氏阴性菌感染的抗菌药物组合物 |
AU2017279027A1 (en) | 2016-06-08 | 2018-12-20 | Glaxosmithkline Intellectual Property Development Limited | Chemical Compounds |
CN106902116B (zh) * | 2017-02-28 | 2021-03-23 | 丹诺医药(苏州)有限公司 | 一种利福霉素-喹嗪酮双靶标分子的应用 |
CN106822125A (zh) * | 2017-02-28 | 2017-06-13 | 丹诺医药(苏州)有限公司 | 一种利福霉素‑喹嗪酮双靶标分子的新用途 |
CN109251258B (zh) * | 2017-07-13 | 2021-06-01 | 中国石油天然气股份有限公司 | 宽分布聚丙烯催化组分、组分制备方法及其催化剂 |
WO2019027860A1 (en) * | 2017-08-01 | 2019-02-07 | Boehringer Ingelheim International Gmbh | INTERMEDIATE COMPOUNDS AND METHODS |
CN108310393A (zh) * | 2018-02-12 | 2018-07-24 | 丹诺医药(苏州)有限公司 | 一种利福霉素-喹嗪酮偶联分子的应用 |
CN109464673A (zh) * | 2019-01-08 | 2019-03-15 | 丹诺医药(苏州)有限公司 | 利福霉素-喹嗪酮偶联分子及其盐的应用和制剂 |
CN109529045B (zh) * | 2019-01-08 | 2021-05-18 | 丹诺医药(苏州)有限公司 | 利福霉素-喹嗪酮偶联分子及其药学上可接受的盐的应用 |
CN109942474B (zh) * | 2019-03-04 | 2020-09-18 | 华中科技大学 | 一种邻叠氮-肼类化合物及其制备方法 |
CN115501230B (zh) * | 2022-08-05 | 2023-11-21 | 丹诺医药(苏州)有限公司 | 利福霉素-喹嗪酮偶联分子软膏剂及其制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2088870T3 (es) * | 1988-03-18 | 1996-10-01 | Kanegafuchi Chemical Ind | Un derivado de benzoxazinorrifamicina sustituida, un procedimiento para preparar el mismo y un agente antibacteriano que contiene el mismo. |
DK0700399T3 (da) | 1993-05-24 | 2001-11-26 | Lepetit Spa | Derivater i 36-stilling af rifamyciner og anvendelse af sådanne som antimikrobemidler |
EP1453837A4 (en) * | 2001-11-21 | 2007-11-07 | Activbiotics Inc | TARGETED THERAPEUTIC AGENTS AND USES THEREOF |
WO2005070941A1 (en) | 2004-01-13 | 2005-08-04 | Cumbre Pharmaceuticals Inc. | Rifamycin imino derivatives effective against drug-resistant microbes |
US7247634B2 (en) | 2004-01-13 | 2007-07-24 | Cumbre Pharmaceuticals Inc. | Rifamycin derivatives effective against drug-resistant microbes |
-
2005
- 2005-07-21 DE DE602005013671T patent/DE602005013671D1/de active Active
- 2005-07-21 CA CA2574301A patent/CA2574301C/en active Active
- 2005-07-21 US US11/186,425 patent/US7226931B2/en active Active
- 2005-07-21 JP JP2007522765A patent/JP5153329B2/ja active Active
- 2005-07-21 AT AT05791212T patent/ATE427311T1/de not_active IP Right Cessation
- 2005-07-21 JP JP2007522780A patent/JP5236944B2/ja active Active
- 2005-07-21 CN CN2005800308596A patent/CN101031572B/zh active Active
- 2005-07-21 EP EP05791212A patent/EP1768987B1/en active Active
- 2005-07-21 CA CA002574307A patent/CA2574307A1/en not_active Abandoned
- 2005-07-21 AU AU2005267054A patent/AU2005267054B2/en active Active
- 2005-07-21 NZ NZ565002A patent/NZ565002A/en active Application Filing
- 2005-07-21 WO PCT/US2005/025924 patent/WO2006012443A1/en active Application Filing
- 2005-07-21 CN CNA2005800316554A patent/CN101065385A/zh active Pending
- 2005-07-21 US US11/186,187 patent/US7229996B2/en active Active
- 2005-07-21 EP EP05773711A patent/EP1781670A1/en not_active Withdrawn
- 2005-07-21 WO PCT/US2005/025969 patent/WO2006012470A1/en active Application Filing
-
2007
- 2007-10-04 HK HK07110800.2A patent/HK1102808A1/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CA2574301A1 (en) | 2006-02-02 |
WO2006012443A1 (en) | 2006-02-02 |
CA2574301C (en) | 2013-09-10 |
NZ565002A (en) | 2009-08-28 |
AU2005267054B2 (en) | 2011-06-23 |
CA2574307A1 (en) | 2006-02-02 |
EP1768987B1 (en) | 2009-04-01 |
US7229996B2 (en) | 2007-06-12 |
JP2008507549A (ja) | 2008-03-13 |
JP2008507548A (ja) | 2008-03-13 |
AU2005267054A1 (en) | 2006-02-02 |
DE602005013671D1 (de) | 2009-05-14 |
CN101065385A (zh) | 2007-10-31 |
WO2006012470A1 (en) | 2006-02-02 |
US20060019985A1 (en) | 2006-01-26 |
CN101031572B (zh) | 2010-12-08 |
US20060019986A1 (en) | 2006-01-26 |
JP5236944B2 (ja) | 2013-07-17 |
JP5153329B2 (ja) | 2013-02-27 |
EP1781670A1 (en) | 2007-05-09 |
CN101031572A (zh) | 2007-09-05 |
ATE427311T1 (de) | 2009-04-15 |
EP1768987A1 (en) | 2007-04-04 |
US7226931B2 (en) | 2007-06-05 |
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