HK1098124A1 - Novel method for the preparation of intermediates useful for the synthesis of vitamin d analogues - Google Patents

Novel method for the preparation of intermediates useful for the synthesis of vitamin d analogues

Info

Publication number
HK1098124A1
HK1098124A1 HK07104323.3A HK07104323A HK1098124A1 HK 1098124 A1 HK1098124 A1 HK 1098124A1 HK 07104323 A HK07104323 A HK 07104323A HK 1098124 A1 HK1098124 A1 HK 1098124A1
Authority
HK
Hong Kong
Prior art keywords
analogues
vitamin
synthesis
preparation
novel method
Prior art date
Application number
HK07104323.3A
Other languages
English (en)
Inventor
Erik Torngard Hansen
Thomas Peter Sabroe
Martin John Calverley
Hendrik Pedersen
Heinz-Jozef Wilhelm Deussen
Original Assignee
Leo Pharma As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharma As filed Critical Leo Pharma As
Publication of HK1098124A1 publication Critical patent/HK1098124A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B37/00—Reactions without formation or introduction of functional groups containing hetero atoms, involving either the formation of a carbon-to-carbon bond between two carbon atoms not directly linked already or the disconnection of two directly linked carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/72—Benzo[c]thiophenes; Hydrogenated benzo[c]thiophenes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK07104323.3A 2004-04-02 2007-04-24 Novel method for the preparation of intermediates useful for the synthesis of vitamin d analogues HK1098124A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55854604P 2004-04-02 2004-04-02
PCT/DK2005/000203 WO2005095336A2 (en) 2004-04-02 2005-03-23 Novel method for the preparation of intermediates useful for the synthesis of vitamin d analogues

Publications (1)

Publication Number Publication Date
HK1098124A1 true HK1098124A1 (en) 2007-07-13

Family

ID=34961754

Family Applications (1)

Application Number Title Priority Date Filing Date
HK07104323.3A HK1098124A1 (en) 2004-04-02 2007-04-24 Novel method for the preparation of intermediates useful for the synthesis of vitamin d analogues

Country Status (19)

Country Link
US (1) US20070135395A1 (ru)
EP (1) EP1735276B1 (ru)
JP (1) JP4744507B2 (ru)
KR (1) KR20070056001A (ru)
CN (1) CN1938268B (ru)
AR (1) AR048462A1 (ru)
AT (1) ATE498609T1 (ru)
BR (1) BRPI0508704A (ru)
CA (1) CA2561590C (ru)
DE (2) DE05715124T1 (ru)
ES (1) ES2361389T3 (ru)
HK (1) HK1098124A1 (ru)
IL (1) IL177357A (ru)
MX (1) MXPA06010824A (ru)
MY (1) MY146099A (ru)
RU (1) RU2378252C2 (ru)
TW (1) TWI322800B (ru)
UA (1) UA94568C2 (ru)
WO (1) WO2005095336A2 (ru)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1948283B (zh) * 2005-10-14 2010-12-29 台耀化学股份有限公司 维生素d衍生物的制备方法
EP1844010B1 (en) 2006-03-17 2013-02-13 Leo Pharma A/S Isomerisation of pharmaceutical intermediates
WO2009057136A2 (en) * 2007-08-03 2009-05-07 Glenmark Generics Limited Epimerization by stereoselective synthesis of vitamin d analogues
WO2009153782A1 (en) * 2008-06-17 2009-12-23 Ben Gurion University Of The Negev R&D Authority Substituted cyclohexylidene-ethylidene-octahydro-indene compounds
US20120184514A1 (en) * 2009-07-01 2012-07-19 Vitamin Derivatives Inc. Vitamin d compounds and methods for preparing same
CN101607932B (zh) * 2009-07-23 2012-05-09 青岛正大海尔制药有限公司 一种光化学反应制备骨化三醇的方法及其装置
CN103980172A (zh) * 2014-04-26 2014-08-13 湖南华腾制药有限公司 一种1α,25-二羟基维生素D2的制备方法
CN103980173A (zh) * 2014-04-26 2014-08-13 湖南华腾制药有限公司 一种帕立骨化醇中间体的制备方法
CN105624215B (zh) * 2014-10-27 2020-10-27 天津金耀集团有限公司 一种卡泊三醇合成新方法
CN104447211A (zh) * 2014-12-12 2015-03-25 重庆华邦制药有限公司 维生素d类药物的中间体化合物及制备方法
CN105777665B (zh) * 2014-12-17 2018-11-06 上虞京新药业有限公司 卡泊三醇的中间体化合物及其制备方法
ES2575744B1 (es) * 2014-12-30 2017-02-09 Laboratorios Viñas S.A. Procedimiento para proteger derivados de vitamina D con SO2 y uso correspondiente
CN106905358B (zh) * 2015-12-23 2020-12-01 重庆华邦胜凯制药有限公司 一种制备维生素d3类似物中间体的方法
CN105717206B (zh) * 2016-01-27 2018-02-06 重庆华邦制药有限公司 分离测定卡泊三醇中间体f及其杂质的方法
CN107643354B (zh) * 2016-07-22 2022-02-01 重庆华邦胜凯制药有限公司 卡泊三醇起始原料a及相关杂质的分离与测定方法
ES2674336B1 (es) * 2016-12-28 2019-04-11 Laboratorios Vinas S A Procedimiento para reducir derivados carbonilicos de vitamina d y uso correspondiente
CN113845541B (zh) * 2021-10-19 2023-11-07 重庆华邦胜凯制药有限公司 一种制备维生素d3类似物的方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU603340B2 (en) * 1985-08-02 1990-11-15 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Novel vitamin d analogues
US5247104A (en) * 1992-11-04 1993-09-21 Wisconsin Alumni Research Foundation Preparation of 1α, 24-dihydroxyvitamin D analogs
JPH08325226A (ja) * 1995-05-30 1996-12-10 Teijin Ltd ビタミンｄ３ 誘導体の製造法
KR20050055784A (ko) * 2002-10-23 2005-06-13 레오 파마 에이/에스 비타민 디 유사체, 이 유사체를 포함하는 조성물 및 이들의용도
ES2233209B1 (es) * 2003-11-28 2006-04-01 Laboratorios Viñas S.A. Compuestos monohalogenovinilderivados de vitamina d.
EP1730108B1 (en) * 2004-03-18 2008-03-26 Leo Pharma A/S Stereoselective synthesis of vitamin d analogues

Also Published As

Publication number Publication date
CN1938268A (zh) 2007-03-28
DE602005026378D1 (de) 2011-03-31
DE05715124T1 (de) 2008-02-21
RU2006138613A (ru) 2008-05-10
MXPA06010824A (es) 2007-01-17
KR20070056001A (ko) 2007-05-31
MY146099A (en) 2012-06-29
CA2561590A1 (en) 2005-10-13
EP1735276B1 (en) 2011-02-16
UA94568C2 (ru) 2011-05-25
IL177357A (en) 2008-04-13
BRPI0508704A (pt) 2007-08-07
ATE498609T1 (de) 2011-03-15
CN1938268B (zh) 2010-06-02
TWI322800B (en) 2010-04-01
JP2007530602A (ja) 2007-11-01
US20070135395A1 (en) 2007-06-14
EP1735276A2 (en) 2006-12-27
TW200613257A (en) 2006-05-01
JP4744507B2 (ja) 2011-08-10
WO2005095336A2 (en) 2005-10-13
CA2561590C (en) 2008-11-18
RU2378252C2 (ru) 2010-01-10
ES2361389T3 (es) 2011-06-16
AR048462A1 (es) 2006-04-26
WO2005095336A3 (en) 2005-11-10

Similar Documents

Publication Publication Date Title
HK1098124A1 (en) Novel method for the preparation of intermediates useful for the synthesis of vitamin d analogues
KR101434673B9 (ko) 할리콘드린 ｂ 유사체의 제조를 위한 중간체
PT1778618E (pt) Síntese de trietilenotetraminas
HK1108157A1 (en) Intermediates for the preparation of dioxane-2-alkyl carbamates
SI1807395T1 (sl) Proces za sintezo N-alkoksiaminov
EP1711484A4 (en) SYNTHESIS OF CYANOIMINO-BENZOIMIDAZOLES
EG25686A (en) Method of producing aminophenol compounds
HUP0500537A2 (en) Process for the preparation of rosuvastatin via new intermediates
IL181185A0 (en) Novel polymorphs of azabicyclohexane
HK1098122A1 (en) Stereoselective synthesis of vitamin d analogues
IL184715A0 (en) Process for the preparation of intermediates
EP2147916A4 (en) PROCESS FOR THE PREPARATION OF SYNTHETIC TAXANES
IL178184A0 (en) Synthesis of pyrrole-2-carbonitriles
EP1598360A4 (en) NEW INTERMEDIATES FOR THE SYNTHESIS OF DERIVATIVES OF VITAMIN D
IL162071A (en) Process for synthesis of dinitrotetraoxadiazaisowurtzitane (dtiw)
SI1622926T1 (sl) Nov postopek in intermediati za pripravo 17-halogen-19-nor-steroidnih spojin
IL179724A0 (en) Method for producing acetamidopyrrolidine derivatives and novel benzamidoacetic acid derivatives as intermediates therefor
GB0412744D0 (en) Methods for the synthesis of dictyostatin and derivatives and analogues thereofand novel dictyostatin compounds and synthetic intermediates
IL201472A0 (en) Intermediates for the preparation of dioxane-2-alkyl carbamates
PL1591434T3 (pl) Nowe 1-metoksy-2-fenylo-etyleny przydatne do otrzymywania 5-karboksyaldehydu-2-3-dihydrobenzoksepin
AU2004901802A0 (en) Process for the preparation of intermediates
SI1709057T1 (sl) Sinteza spongozina

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20230323