HK1097859A1 - Anti-cd38 human antibodies and uses therefor -cd38 - Google Patents
Anti-cd38 human antibodies and uses therefor -cd38Info
- Publication number
- HK1097859A1 HK1097859A1 HK07104826.5A HK07104826A HK1097859A1 HK 1097859 A1 HK1097859 A1 HK 1097859A1 HK 07104826 A HK07104826 A HK 07104826A HK 1097859 A1 HK1097859 A1 HK 1097859A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- human antibodies
- uses therefor
- therefor
- antibodies
- human
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/005—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Rheumatology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54191104P | 2004-02-06 | 2004-02-06 | |
US54758404P | 2004-02-26 | 2004-02-26 | |
US55394804P | 2004-03-18 | 2004-03-18 | |
US59901404P | 2004-08-06 | 2004-08-06 | |
US61447104P | 2004-10-01 | 2004-10-01 | |
PCT/IB2005/002476 WO2005103083A2 (en) | 2004-02-06 | 2005-02-07 | Anti-cd38 human antibodies and uses therefor |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1097859A1 true HK1097859A1 (en) | 2007-07-06 |
Family
ID=37054659
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK07104826.5A HK1097859A1 (en) | 2004-02-06 | 2007-05-07 | Anti-cd38 human antibodies and uses therefor -cd38 |
Country Status (19)
Country | Link |
---|---|
EP (3) | EP2511297B1 (xx) |
JP (4) | JP2008504013A (xx) |
KR (2) | KR20140066259A (xx) |
BR (1) | BRPI0507489A (xx) |
CY (1) | CY1116458T1 (xx) |
DK (2) | DK1720907T3 (xx) |
ES (2) | ES2541436T3 (xx) |
HK (1) | HK1097859A1 (xx) |
HR (1) | HRP20150641T1 (xx) |
HU (1) | HUE025369T2 (xx) |
IL (1) | IL177242A (xx) |
ME (1) | ME02245B (xx) |
NO (1) | NO20063986L (xx) |
NZ (1) | NZ548990A (xx) |
PL (1) | PL2511297T3 (xx) |
PT (1) | PT2511297E (xx) |
RS (1) | RS54056B1 (xx) |
SG (1) | SG142330A1 (xx) |
WO (1) | WO2005103083A2 (xx) |
Families Citing this family (94)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7658924B2 (en) | 2001-10-11 | 2010-02-09 | Amgen Inc. | Angiopoietin-2 specific binding agents |
CA2555185C (en) | 2004-02-06 | 2020-03-24 | Morphosys Ag | Anti-cd38 human antibodies and uses therefor |
US9200061B2 (en) | 2004-02-06 | 2015-12-01 | Morpho Sys AG | Generation and profiling of fully human HuCAL gold®-derived therapeutic antibodies specific for human CD3i |
NZ548990A (en) | 2004-02-06 | 2009-06-26 | Morphosys Ag | Anti-CD38 human antibodies and uses therefor |
EP2551282A3 (en) | 2005-03-23 | 2013-02-13 | Genmab A/S | Antibodies against CD38 for treatment of multiple myeloma |
CN103554260A (zh) | 2005-10-12 | 2014-02-05 | 莫佛塞斯公司 | 特异性针对人CD38的完全人HuCAL GOLD-衍生治疗抗体的生成和鉴定 |
EA035459B1 (ru) | 2005-12-29 | 2020-06-19 | Сентокор, Инк. | Антитело против il-23p19 |
WO2007142241A1 (ja) * | 2006-06-05 | 2007-12-13 | Hiroshima University | 抗cd38抗体を細胞表面に有する免疫担当細胞 |
EP3753576A1 (en) * | 2006-09-26 | 2020-12-23 | Genmab A/S | Combination treatment of cd38-expressing tumors |
EP1914242A1 (en) | 2006-10-19 | 2008-04-23 | Sanofi-Aventis | Novel anti-CD38 antibodies for the treatment of cancer |
AU2013209322A1 (en) * | 2006-10-19 | 2013-08-15 | Sanofi-Aventis | Novel anti-cd38 antibodies for the treatment of cancer |
JO2913B1 (en) | 2008-02-20 | 2015-09-15 | امجين إنك, | Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses |
EP2191841A1 (en) | 2008-11-28 | 2010-06-02 | Sanofi-Aventis | Antitumor combinations containing antibodies recognizing specifically CD38 and vincristine |
EP2191840A1 (en) | 2008-11-28 | 2010-06-02 | Sanofi-Aventis | Antitumor combinations containing antibodies recognizing specifically CD38 and melphalan |
WO2010079189A1 (en) | 2009-01-09 | 2010-07-15 | Morphosys Ag | Display vectors and methods and uses thereof |
LT2580243T (lt) | 2010-06-09 | 2020-01-27 | Genmab A/S | Antikūnai prieš žmogaus cd38 |
WO2012041800A1 (en) | 2010-09-27 | 2012-04-05 | Morphosys Ag | Anti-cd38 antibody and lenalidomide or bortezomib for the treatment of multiple myeloma and nhl |
MX2013003828A (es) * | 2010-10-05 | 2013-06-28 | Daiichi Sankyo Co Ltd | Anticuerpo dirigido a la proteina lectina tipo inmunoglobulina de union a acido sialico-15 relacionada con osteoclastos. |
UA112170C2 (uk) | 2010-12-10 | 2016-08-10 | Санофі | Протипухлинна комбінація, що містить антитіло, яке специфічно розпізнає cd38, і бортезоміб |
KR102037541B1 (ko) | 2011-10-28 | 2019-10-29 | 테바 파마슈티컬즈 오스트레일리아 피티와이 엘티디 | 폴리펩티드 구축물 및 이의 용도 |
DK2900232T3 (en) | 2012-09-25 | 2018-02-05 | Morphosys Ag | Combinations and use thereof |
EP2914302B1 (en) | 2012-11-05 | 2017-01-04 | MorphoSys AG | Radiolabelled antibody and uses thereof |
JP2014117191A (ja) * | 2012-12-13 | 2014-06-30 | Fisheries Research Agency | リン酸化中性スフィンゴミエリナーゼ1、抗リン酸化中性スフィンゴミエリナーゼ1抗体、中性スフィンゴミエリナーゼ1変異体、及びそれらの用途 |
WO2014110601A1 (en) | 2013-01-14 | 2014-07-17 | Xencor, Inc. | Novel heterodimeric proteins |
US10858417B2 (en) | 2013-03-15 | 2020-12-08 | Xencor, Inc. | Heterodimeric proteins |
US11117975B2 (en) | 2013-04-29 | 2021-09-14 | Teva Pharmaceuticals Australia Pty Ltd | Anti-CD38 antibodies and fusions to attenuated interferon alpha-2B |
FI3677591T3 (fi) * | 2013-04-29 | 2023-04-03 | Teva Pharmaceuticals Australia Pty Ltd | Anti-cd38-vasta-aineet ja fuusiot heikennetylle interferonille alfa-2b |
SG10201909806SA (en) | 2013-11-04 | 2019-11-28 | Glenmark Pharmaceuticals Sa | Production of t cell retargeting hetero-dimeric immunoglobulins |
US9732154B2 (en) | 2014-02-28 | 2017-08-15 | Janssen Biotech, Inc. | Anti-CD38 antibodies for treatment of acute lymphoblastic leukemia |
US9603927B2 (en) | 2014-02-28 | 2017-03-28 | Janssen Biotech, Inc. | Combination therapies with anti-CD38 antibodies |
PL3122781T3 (pl) * | 2014-03-28 | 2020-06-15 | Xencor, Inc. | Dwuswoiste przeciwciała, które wiążą się z CD38 i CD3 |
UA119352C2 (uk) | 2014-05-01 | 2019-06-10 | Тева Фармасьютикалз Острейліа Пті Лтд | Комбінація леналідоміду або помалідоміду і конструкції анти-cd38 антитіло-атенуйований інтерферон альфа-2b та спосіб лікування суб'єкта, який має cd38-експресуючу пухлину |
WO2015195555A1 (en) | 2014-06-16 | 2015-12-23 | The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Blocking cd38 using anti-cd38 antibody conjugated to protein g to protect nk cells |
US10106620B2 (en) | 2014-06-16 | 2018-10-23 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Blocking CD38 using anti-CD38 F(ab′)2 to protect NK cells |
WO2016040294A2 (en) | 2014-09-09 | 2016-03-17 | Janssen Biotech, Inc. | Combination therapies with anti-cd38 antibodies |
UA125637C2 (uk) | 2014-10-29 | 2022-05-11 | Тева Фармасьютікалз Острейліа Пті Лтд | ЗЛИТИЙ ПОЛІПЕПТИД ІНТЕРФЕРОНУ <font face="Symbol">a2</font>b |
MA40894A (fr) * | 2014-11-04 | 2017-09-12 | Glenmark Pharmaceuticals Sa | Immunoglobulines hétéro-dimères reciblant des lymphocytes t cd3/cd38 et leurs procédés de production |
US11773166B2 (en) | 2014-11-04 | 2023-10-03 | Ichnos Sciences SA | CD3/CD38 T cell retargeting hetero-dimeric immunoglobulins and methods of their production |
BR112017011092A2 (pt) | 2014-11-26 | 2017-12-26 | Xencor Inc | anticorpos heterodiméricos que ligam cd3 e antígenos de tumor |
US10259887B2 (en) | 2014-11-26 | 2019-04-16 | Xencor, Inc. | Heterodimeric antibodies that bind CD3 and tumor antigens |
CA2969717A1 (en) | 2014-12-04 | 2016-06-09 | Janssen Biotech, Inc. | Anti-cd38 antibodies for treatment of acute myeloid leukemia |
EP4180058A1 (en) * | 2015-04-08 | 2023-05-17 | Sorrento Therapeutics, Inc. | Antibody therapeutics that bind cd38 |
HUE054271T2 (hu) | 2015-05-13 | 2021-08-30 | Morphosys Ag | Mielóma Multiplex (MM) kezelése |
JP6827426B2 (ja) | 2015-05-20 | 2021-02-10 | ヤンセン バイオテツク,インコーポレーテツド | 軽鎖アミロイドーシス及びその他のcd38陽性血液悪性疾患の治療のための抗cd38抗体 |
KR102647100B1 (ko) | 2015-05-30 | 2024-03-13 | 몰레큘러 템플레이츠, 인코퍼레이션. | 탈면역된 시가 독소 a 서브유닛 스캐폴드 및 이를 포함하는 세포-표적화 분자 |
MX2018000265A (es) | 2015-06-22 | 2018-05-23 | Janssen Biotech Inc | Terapias de combinacion para enfermedades malignas hematologicas con anticuerpos anti-cd38 e inhibidores de survivina. |
US20170044265A1 (en) | 2015-06-24 | 2017-02-16 | Janssen Biotech, Inc. | Immune Modulation and Treatment of Solid Tumors with Antibodies that Specifically Bind CD38 |
PE20181090A1 (es) | 2015-06-24 | 2018-07-09 | Janssen Biotech Inc | Modulacion y tratamiento inmunes de tumores solidos con anticuerpos que se unen especificamente a cd38 |
US10781261B2 (en) | 2015-11-03 | 2020-09-22 | Janssen Biotech, Inc. | Subcutaneous formulations of anti-CD38 antibodies and their uses |
RS63210B1 (sr) | 2015-11-03 | 2022-06-30 | Janssen Biotech Inc | Potkožne formulacije anti-cd38 antitela i njihova upotreba |
JP7362250B2 (ja) | 2016-03-04 | 2023-10-17 | モルフォシス・アーゲー | 多発性骨髄腫におけるmタンパク質反応の臨床評価 |
WO2018002181A1 (en) | 2016-06-28 | 2018-01-04 | Umc Utrecht Holding B.V. | TREATMENT OF IgE-MEDIATED DISEASES WITH ANTIBODIES THAT SPECIFICALLY BIND CD38 |
EP3487506A1 (en) | 2016-07-20 | 2019-05-29 | Hybrigenics SA | Combinations of inecalcitol with an anti-cd38 agent and their uses for treating cancer |
CN117534754A (zh) | 2017-06-08 | 2024-02-09 | 黑带医疗有限公司 | Cd38调节抗体 |
EP3641831A1 (en) | 2017-06-20 | 2020-04-29 | Sorrento Therapeutics, Inc. | Cd38 antibody drug conjugate |
US10899798B2 (en) | 2017-06-26 | 2021-01-26 | Bicyclerd Limited | Bicyclic peptide ligands with detectable moieties and uses thereof |
US11236173B2 (en) | 2017-08-16 | 2022-02-01 | Black Belt Therapeutics Limited | CD38 antibody |
US11542338B2 (en) | 2017-08-16 | 2023-01-03 | Black Belt Therapeutics Limited | CD38 modulating antibody |
KR20200061402A (ko) * | 2017-10-10 | 2020-06-02 | 사노피 | 항-cd38 항체 및 항-cd3 및 항-cd28 항체와의 조합 |
JP2021502961A (ja) | 2017-10-31 | 2021-02-04 | ヤンセン バイオテツク,インコーポレーテツド | 高リスク多発性骨髄腫の治療方法 |
TWI825046B (zh) | 2017-12-19 | 2023-12-11 | 英商拜西可泰克斯有限公司 | Epha2特用之雙環胜肽配位基 |
GB201721265D0 (en) | 2017-12-19 | 2018-01-31 | Bicyclerd Ltd | Bicyclic peptide ligands specific for EphA2 |
WO2019149743A1 (en) | 2018-01-30 | 2019-08-08 | Cellectis | Combination comprising allogeneic immune cells deficient for an antigen present on both t-cells and pathological cells and therapeutic antibody against said antigen |
CN110144008B (zh) | 2018-02-12 | 2021-03-19 | 杭州尚健生物技术有限公司 | Cd38蛋白抗体及其应用 |
GB201810320D0 (en) | 2018-06-22 | 2018-08-08 | Bicycletx Ltd | Peptide ligands for binding to CD38 |
US11180531B2 (en) | 2018-06-22 | 2021-11-23 | Bicycletx Limited | Bicyclic peptide ligands specific for Nectin-4 |
GB201810316D0 (en) | 2018-06-22 | 2018-08-08 | Bicyclerd Ltd | Peptide ligands for binding to EphA2 |
CN113195540A (zh) | 2018-10-17 | 2021-07-30 | 詹森生物科技公司 | 提供皮下施用抗cd38抗体的方法 |
CN113395979A (zh) | 2018-11-20 | 2021-09-14 | 詹森生物科技公司 | 用抗il-23特异性抗体治疗银屑病的安全且有效的方法 |
CN113194925A (zh) | 2018-12-14 | 2021-07-30 | 莫佛塞斯公司 | 抗体制剂 |
GB201900530D0 (en) | 2019-01-15 | 2019-03-06 | Bicyclerd Ltd | Bicyclic peptide ligands specific for CD38 |
GB201900529D0 (en) | 2019-01-15 | 2019-03-06 | Bicycletx Ltd | Bicyclic peptide ligands specific for CD38 |
SG11202107319PA (en) | 2019-03-15 | 2021-08-30 | Morphosys Ag | Anti-cd38 antibodies and pharmaceutical compositions thereof for the treatment of autoantibody-mediated autoimmune disease |
US11780911B2 (en) | 2019-05-23 | 2023-10-10 | Janssen Biotech, Inc. | Method of treating inflammatory bowel disease with a combination therapy of antibodies to IL-23 and TNF alpha |
WO2020261219A1 (en) | 2019-06-27 | 2020-12-30 | Crispr Therapeutics Ag | Use of chimeric antigen receptor t cells and nk cell inhibitors for treating cancer |
MX2021015433A (es) | 2019-07-02 | 2022-06-08 | Hutchinson Fred Cancer Res | Vectores ad35 recombinantes y mejoras de la terapia génica relacionadas. |
TW202110485A (zh) | 2019-07-30 | 2021-03-16 | 英商拜西可泰克斯有限公司 | 異質雙環肽複合物 |
WO2021260657A1 (en) | 2020-06-26 | 2021-12-30 | Crispr Therapeutics Ag | Allogeneic cell therapy of b cell malignancies using genetically engineered t cells targeting cd19 |
CN114075283A (zh) * | 2020-08-12 | 2022-02-22 | 三生国健药业(上海)股份有限公司 | 结合人cd38的抗体、其制备方法和用途 |
CN114195893A (zh) * | 2020-09-17 | 2022-03-18 | 百奥泰生物制药股份有限公司 | 抗整联蛋白抗体或抗原结合片段及其应用 |
GB202016331D0 (en) | 2020-10-15 | 2020-12-02 | Bicyclerd Ltd | Bicyclic peptide ligand drug conjugates |
WO2022137186A1 (en) | 2020-12-23 | 2022-06-30 | Crispr Therapeutics Ag | Cancer treatment using cd38 inhibitor and/or lenalidomide and t-cells expressing a chimeric antigen receptor |
US20240109977A1 (en) | 2021-01-14 | 2024-04-04 | Morphosys Ag | Anti-cd38 antibodies and their uses |
US20220275090A1 (en) | 2021-02-22 | 2022-09-01 | Janssen Biotech, Inc. | Combination Therapies with Anti-CD38 Antibodies and PARP or Adenosine Receptor Inhibitors |
TW202302642A (zh) | 2021-03-01 | 2023-01-16 | 德商莫菲西斯公司 | 用於治療抗體介導移植物排斥用途之抗cd38抗體 |
KR20230156079A (ko) | 2021-03-09 | 2023-11-13 | 젠코어 인코포레이티드 | Cd3과 cldn6에 결합하는 이종이량체 항체 |
US11859012B2 (en) | 2021-03-10 | 2024-01-02 | Xencor, Inc. | Heterodimeric antibodies that bind CD3 and GPC3 |
US20220378829A1 (en) | 2021-05-12 | 2022-12-01 | Crispr Therapeutics Ag | Genetically engineered immune cells targeting cd70 for use in treating solid tumors |
TW202310870A (zh) | 2021-05-12 | 2023-03-16 | 瑞士商Crispr治療公司 | 用於治療造血惡性腫瘤之靶向cd70的基因工程化免疫細胞 |
TW202321303A (zh) | 2021-07-19 | 2023-06-01 | 德商莫菲西斯公司 | 抗pla2r自體抗體媒介膜性腎病變之治療 |
WO2023079494A1 (en) | 2021-11-03 | 2023-05-11 | Janssen Biotech, Inc. | Corticosteriod reduction in treatment with anti-cd38 antibodies |
CN116547307A (zh) * | 2021-12-03 | 2023-08-04 | 南京维立志博生物科技有限公司 | 结合cd38的抗体及其用途 |
WO2023144303A1 (en) | 2022-01-31 | 2023-08-03 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Cd38 as a biomarker and biotarget in t-cell lymphomas |
WO2024079010A1 (en) | 2022-10-10 | 2024-04-18 | F. Hoffmann-La Roche Ag | Combination therapy of a gprc5d tcb and cd38 antibodies |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020164788A1 (en) | 1994-12-02 | 2002-11-07 | The Wellcome Foundation Limited | Humanized antibodies to CD38 |
GB9424449D0 (en) | 1994-12-02 | 1995-01-18 | Wellcome Found | Antibodies |
JP4436457B2 (ja) | 1995-08-18 | 2010-03-24 | モルフォシス アイピー ゲーエムベーハー | 蛋白質/(ポリ)ペプチドライブラリー |
JP2000316578A (ja) * | 1999-05-12 | 2000-11-21 | Bml Inc | 糖尿病発症危険因子の検出方法 |
EP1144607B1 (en) | 1999-07-20 | 2008-12-17 | MorphoSys AG | Methods for displaying (poly)peptides/proteins on bacteriophage particles via disulfide bonds |
EP1174440A1 (en) | 2000-07-19 | 2002-01-23 | U-BISys B.V. | A selectively-expressed epitope on the human CD38 molecule detected by a phage display library-derived human scFv antibody fragment |
CA2445168A1 (en) * | 2001-04-24 | 2002-10-31 | Bayer Corporation | Human timp-1 antibodies |
AR038568A1 (es) * | 2002-02-20 | 2005-01-19 | Hoffmann La Roche | Anticuerpos anti-a beta y su uso |
NZ548990A (en) * | 2004-02-06 | 2009-06-26 | Morphosys Ag | Anti-CD38 human antibodies and uses therefor |
AR053489A1 (es) | 2005-05-24 | 2007-05-09 | Morphosys Ag | Generacion perfilado de anticuerpos terapeuticos totalmente derivados de hucal gold humanos especificos para cd38 humano |
DK2500360T3 (en) | 2005-10-31 | 2015-10-26 | Oncomed Pharm Inc | Compositions and methods for the diagnosis and treatment of cancer |
JP2012022417A (ja) * | 2010-07-12 | 2012-02-02 | Humony Co Ltd | 電子請求処理サービスシステム及び該電子請求処理サービスシステム用のアプリケーション |
JP6257929B2 (ja) * | 2013-06-13 | 2018-01-10 | 東芝メディカルシステムズ株式会社 | X線コンピュータ断層撮影装置 |
-
2005
- 2005-02-07 NZ NZ548990A patent/NZ548990A/en not_active IP Right Cessation
- 2005-02-07 PT PT111961728T patent/PT2511297E/pt unknown
- 2005-02-07 SG SG200803286-4A patent/SG142330A1/en unknown
- 2005-02-07 WO PCT/IB2005/002476 patent/WO2005103083A2/en active Application Filing
- 2005-02-07 RS RS20150390A patent/RS54056B1/en unknown
- 2005-02-07 DK DK05769690.8T patent/DK1720907T3/en active
- 2005-02-07 BR BRPI0507489-4A patent/BRPI0507489A/pt not_active Application Discontinuation
- 2005-02-07 EP EP11196172.8A patent/EP2511297B1/en not_active Revoked
- 2005-02-07 DK DK11196172.8T patent/DK2511297T3/en active
- 2005-02-07 EP EP05769690.8A patent/EP1720907B1/en active Active
- 2005-02-07 PL PL11196172T patent/PL2511297T3/pl unknown
- 2005-02-07 ES ES05769690.8T patent/ES2541436T3/es active Active
- 2005-02-07 HU HUE11196172A patent/HUE025369T2/en unknown
- 2005-02-07 EP EP15151492.4A patent/EP2915820A1/en not_active Ceased
- 2005-02-07 JP JP2006551957A patent/JP2008504013A/ja not_active Withdrawn
- 2005-02-07 ES ES11196172.8T patent/ES2541489T3/es active Active
- 2005-02-07 KR KR1020147011314A patent/KR20140066259A/ko not_active Application Discontinuation
- 2005-02-07 KR KR1020137028482A patent/KR20130126747A/ko not_active IP Right Cessation
-
2006
- 2006-08-02 IL IL177242A patent/IL177242A/en active IP Right Grant
- 2006-09-05 NO NO20063986A patent/NO20063986L/no not_active Application Discontinuation
-
2007
- 2007-05-07 HK HK07104826.5A patent/HK1097859A1/xx unknown
-
2012
- 2012-02-03 JP JP2012022417A patent/JP5926568B2/ja not_active Expired - Fee Related
-
2015
- 2015-01-05 JP JP2015000102A patent/JP2015110597A/ja active Pending
- 2015-06-15 HR HRP20150641TT patent/HRP20150641T1/hr unknown
- 2015-07-02 CY CY20151100576T patent/CY1116458T1/el unknown
-
2016
- 2016-05-17 ME MEP-2015-350A patent/ME02245B/me unknown
- 2016-06-03 JP JP2016111794A patent/JP2016164198A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ES2541489T3 (es) | 2015-07-21 |
NZ548990A (en) | 2009-06-26 |
ME02245B (me) | 2015-10-30 |
KR20130126747A (ko) | 2013-11-20 |
HRP20150641T1 (hr) | 2015-07-17 |
PT2511297E (pt) | 2015-08-24 |
RS54056B1 (en) | 2015-10-30 |
KR20140066259A (ko) | 2014-05-30 |
CY1116458T1 (el) | 2017-03-15 |
EP2511297A1 (en) | 2012-10-17 |
WO2005103083A8 (en) | 2006-10-05 |
JP2016164198A (ja) | 2016-09-08 |
DK2511297T3 (en) | 2015-06-15 |
ES2541436T3 (es) | 2015-07-20 |
PL2511297T3 (pl) | 2015-08-31 |
EP2511297B1 (en) | 2015-04-08 |
DK1720907T3 (en) | 2015-06-15 |
BRPI0507489A (pt) | 2007-07-10 |
EP1720907B1 (en) | 2015-04-08 |
HUE025369T2 (en) | 2016-02-29 |
IL177242A0 (en) | 2006-12-10 |
EP2915820A1 (en) | 2015-09-09 |
JP2012116856A (ja) | 2012-06-21 |
NO20063986L (no) | 2006-11-06 |
IL177242A (en) | 2011-09-27 |
JP5926568B2 (ja) | 2016-05-25 |
EP1720907A2 (en) | 2006-11-15 |
WO2005103083A3 (en) | 2006-11-16 |
JP2008504013A (ja) | 2008-02-14 |
JP2015110597A (ja) | 2015-06-18 |
SG142330A1 (en) | 2008-05-28 |
WO2005103083A2 (en) | 2005-11-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ME02245B (me) | Anti-cd38 humana antitjela i njihove upotrebe | |
SI2511297T1 (sl) | Proti -CD38 humana protitelesa in njihova uporaba | |
IL182554A0 (en) | Anti-addl antibodies and uses thereof | |
IL178356A0 (en) | Dr5 antibodies and uses thereof | |
IL178277A0 (en) | Irta-5 antibodies and their uses | |
IL179476A0 (en) | Antibodies against human interleukin-13 and uses therefor | |
HK1102600A1 (en) | Novel anti-igf-ir antibodies and uses thereof | |
HRP20140271T1 (hr) | Humana antitijela protiv bjesnoä†e i njihova uporaba | |
IL172871A0 (en) | Rg1 antibodies and uses thereof | |
IL222922A (en) | Antibodies against neurophilin-1 and their use | |
ZA200606319B (en) | Anti-CD38 human antibodies and uses therefor | |
IL183458A0 (en) | Anti-il-1r1 single domain antibodies and therapeutic uses | |
IL178593A (en) | Specific antibodies of fcγriib and methods for their use | |
ZA200507067B (en) | Antibodies against human IL-21 receptor and uses therefor | |
ZA200800636B (en) | Novel anti-IGF-IR antibodies and uses thereof | |
EP1787998A4 (en) | ANTIBODIES AND USE RELATING THERETO | |
AP2008004471A0 (en) | Anti-Alpha2 Intergin antibodies and their uses | |
IL184024A0 (en) | Irta-5 antibodies and their uses | |
ZA200703406B (en) | Anti-ADDL antibodies and uses thereof | |
IL179497A0 (en) | Carboranylporphyrins and uses thereof | |
EP1699485A4 (en) | ANTI-HYDROLYSATE ANTIBODIES AND ITS USES | |
IL172510A0 (en) | Antibodies and uses thereof | |
IL180365A0 (en) | Carboranylporphyrins and uses thereof | |
IL172511A0 (en) | Specific human antibodies | |
ZA200702281B (en) | IRTA-4 antibodies and their uses |