HRP20140271T1 - Humana antitijela protiv bjesnoä†e i njihova uporaba - Google Patents

Humana antitijela protiv bjesnoä†e i njihova uporaba

Info

Publication number
HRP20140271T1
HRP20140271T1 HRP20140271TT HRP20140271T HRP20140271T1 HR P20140271 T1 HRP20140271 T1 HR P20140271T1 HR P20140271T T HRP20140271T T HR P20140271TT HR P20140271 T HRP20140271 T HR P20140271T HR P20140271 T1 HRP20140271 T1 HR P20140271T1
Authority
HR
Croatia
Prior art keywords
human antibodies
antibodies against
against rabies
rabies
human
Prior art date
Application number
HRP20140271TT
Other languages
English (en)
Inventor
William D. Thomas
Donna Ambrosino
Robert Mandell
Susan Schonhoff
Gregory J. Babcock
Charles Rupprecht
Original Assignee
University Of Massachusetts
Centers For Disease Control And Prevention
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Massachusetts, Centers For Disease Control And Prevention filed Critical University Of Massachusetts
Publication of HRP20140271T1 publication Critical patent/HRP20140271T1/hr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/205—Rhabdoviridae, e.g. rabies virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14—Specific host cells or culture conditions, e.g. components, pH or temperature
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
HRP20140271TT 2005-02-02 2014-03-21 Humana antitijela protiv bjesnoä†e i njihova uporaba HRP20140271T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64951205P 2005-02-02 2005-02-02
PCT/US2006/003644 WO2006084006A1 (en) 2005-02-02 2006-02-02 Human antibodies against rabies and uses thereof

Publications (1)

Publication Number Publication Date
HRP20140271T1 true HRP20140271T1 (hr) 2014-05-23

Family

ID=36589118

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20140271TT HRP20140271T1 (hr) 2005-02-02 2014-03-21 Humana antitijela protiv bjesnoä†e i njihova uporaba

Country Status (17)

Country Link
US (4) US7727532B2 (hr)
EP (1) EP1851315B1 (hr)
CN (2) CN102936284A (hr)
BR (1) BRPI0606790C8 (hr)
CA (1) CA2596697C (hr)
DK (1) DK1851315T3 (hr)
ES (1) ES2453973T3 (hr)
HK (1) HK1104060A1 (hr)
HR (1) HRP20140271T1 (hr)
ME (1) ME01785B (hr)
MX (1) MX2007009273A (hr)
PL (1) PL1851315T3 (hr)
PT (1) PT1851315E (hr)
RS (1) RS53239B (hr)
SI (1) SI1851315T1 (hr)
WO (1) WO2006084006A1 (hr)
ZA (1) ZA200707339B (hr)

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US8481043B2 (en) * 2001-06-22 2013-07-09 Cpex Pharmaceuticals, Inc. Nasal immunization
RS53239B (en) 2005-02-02 2014-08-29 University Of Massachusetts HUMAN ANTI-ANTIBODY ANTIBODIES AND THEIR USES
CA2666974A1 (en) * 2006-10-20 2008-11-06 Schering Corporation Fully human anti-vegf antibodies and methods of using
CN101235086B (zh) * 2007-02-02 2011-06-15 吉林圣元科技有限责任公司 重组人抗狂犬病毒抗体
WO2009042917A1 (en) * 2007-09-28 2009-04-02 The General Hospital Corporation Methods and compositions for antibody production
CN101812130B (zh) * 2010-05-06 2012-07-04 中国疾病预防控制中心病毒病预防控制所 人源抗狂犬病毒糖蛋白中和性抗体(RVFab5)
CN101812131B (zh) * 2010-05-06 2012-07-04 中国疾病预防控制中心病毒病预防控制所 人源抗狂犬病毒糖蛋白中和性抗体(RVFab8)
EP2630242B1 (en) 2010-10-19 2017-08-02 The Government of the United States of America as Represented by the Secretary of the Department of Health and Human Services, Identification of antibodies specific for lyssaviruses
EP4338750A2 (en) 2011-03-11 2024-03-20 Beth Israel Deaconess Medical Center Inc. Anti-cd40 antibodies and uses thereof
WO2013048130A2 (ko) * 2011-09-30 2013-04-04 (주)셀트리온 광견병 바이러스를 중화시킬 수 있는 결합 분자
CN103374069B (zh) * 2012-04-24 2015-06-03 中国科学院上海生命科学研究院 一种抗狂犬病毒的结合分子2e1
CN103374070B (zh) * 2012-04-24 2016-01-27 中国科学院上海生命科学研究院 一种抗狂犬病毒的结合分子2f5
WO2015024665A1 (en) * 2013-08-21 2015-02-26 Curevac Gmbh Rabies vaccine
CN103954777A (zh) * 2014-05-20 2014-07-30 北京凯思百奥科技发展有限公司 一种狂犬病病毒单克隆抗体及其应用
EP3220947B1 (en) 2014-11-18 2020-10-28 Humabs Biomed S.A. Antibodies that potently neutralize rabies virus and other lyssaviruses and uses thereof
CN104722449A (zh) * 2015-04-09 2015-06-24 京东方科技集团股份有限公司 胶涂布头、涂胶设备及触控显示面板的制备方法
CN107709360B (zh) * 2015-06-10 2021-10-19 赛特瑞恩股份有限公司 狂犬病毒g蛋白表位及与其特异性结合的中和狂犬病毒的结合分子
CN108135999B (zh) * 2015-08-13 2022-05-31 马萨诸塞大学 针对狂犬病的人抗体及其用途
AU2016315873B2 (en) 2015-09-04 2022-08-18 Primatope Therapeutics Inc. Humanized anti-CD40 antibodies and uses thereof
ZA201604024B (en) * 2015-09-26 2017-08-30 Serum Institute Of India Pvt Ltd Improved feeding strategies and purification processes for monoclonal antibody production
RU2661028C2 (ru) * 2016-11-11 2018-07-11 федеральное государственное бюджетное учреждение "Национальный исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф.Гамалеи" Министерства здравоохранения Российской Федедерации Фармацевтическая композиция для пассивной иммунизации против бешенства, фармацевтический набор, способ применения фармацевтического набора
CA3047530A1 (en) * 2016-12-23 2018-06-28 Serum Institute Of India Private Limited Improved methods for enhancing antibody productivity in mammalian cell culture and minimizing aggregation during downstream, formulation processes and stable antibody formulationsobtained thereof
CN108359640B (zh) * 2018-01-31 2020-12-01 武汉枢密脑科学技术有限公司 一种标记全脑区神经网络结构的狂犬病毒、其制备和应用
WO2019227039A1 (en) * 2018-05-24 2019-11-28 Lankenau Institute For Medical Research Compositions comprising antibodies to rabies virus and the uses thereof
CN111171145B (zh) * 2020-01-21 2021-11-05 兰州生物制品研究所有限责任公司 一种抗狂犬病病毒单克隆抗体、制备方法及用途

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WO1995009249A1 (en) * 1993-09-30 1995-04-06 Thomas Jefferson University Oral vaccination of mammals
US5840300A (en) * 1995-09-11 1998-11-24 Trustees Of The University Of Pennsylvania Methods and compositions comprising single chain recombinant antibodies
US20040013672A1 (en) * 2000-05-16 2004-01-22 Thomas Jefferson University Recombinant antibodies, and compositions and methods for making and using the same
US6890532B2 (en) * 2000-05-16 2005-05-10 Thomas Jefferson University Rabies virus-specific neutralizing human monoclonal antibodies and nucleic acids and related methods
JP3665316B2 (ja) * 2001-05-18 2005-06-29 麒麟麦酒株式会社 抗ｔｒａｉｌ−ｒ抗体
AU2004270409A1 (en) * 2003-09-04 2005-03-17 Crucell Holland B.V. Antigenic peptides of rabies virus and uses thereof
RS53239B (en) * 2005-02-02 2014-08-29 University Of Massachusetts HUMAN ANTI-ANTIBODY ANTIBODIES AND THEIR USES

Also Published As

Publication number Publication date
EP1851315B1 (en) 2013-12-25
ZA200707339B (en) 2014-04-30
ME01785B (me) 2014-09-20
US20090041777A1 (en) 2009-02-12
RS53239B (en) 2014-08-29
WO2006084006A1 (en) 2006-08-10
CN101133158B (zh) 2012-12-05
BRPI0606790C8 (pt) 2021-05-25
ES2453973T3 (es) 2014-04-09
US20110008360A1 (en) 2011-01-13
US20130039926A1 (en) 2013-02-14
US7727532B2 (en) 2010-06-01
CN101133158A (zh) 2008-02-27
BRPI0606790C1 (pt) 2019-08-06
CA2596697C (en) 2019-04-09
US8226952B2 (en) 2012-07-24
MX2007009273A (es) 2008-02-19
HK1104060A1 (en) 2008-01-04
SI1851315T1 (sl) 2014-06-30
DK1851315T3 (en) 2014-03-24
EP1851315A1 (en) 2007-11-07
BRPI0606790A2 (pt) 2009-07-14
PL1851315T3 (pl) 2014-06-30
US20150315266A1 (en) 2015-11-05
PT1851315E (pt) 2014-03-25
CA2596697A1 (en) 2006-08-10
CN102936284A (zh) 2013-02-20
BRPI0606790B1 (pt) 2018-10-09

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