HK1091131A1 - Use of rotigotine for the treatment of depression - Google Patents
Use of rotigotine for the treatment of depressionInfo
- Publication number
- HK1091131A1 HK1091131A1 HK06111851.9A HK06111851A HK1091131A1 HK 1091131 A1 HK1091131 A1 HK 1091131A1 HK 06111851 A HK06111851 A HK 06111851A HK 1091131 A1 HK1091131 A1 HK 1091131A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- rotigotine
- depression
- treatment
- naphthol
- prodrugs
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10334188A DE10334188B4 (de) | 2003-07-26 | 2003-07-26 | Verwendung von Rotigotin zur Behandlung von Depressionen |
PCT/EP2004/008168 WO2005009424A1 (de) | 2003-07-26 | 2004-07-22 | Verwendung von rotigotin zur behandlung von depressionen |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1091131A1 true HK1091131A1 (en) | 2007-01-12 |
Family
ID=34088862
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK06111851.9A HK1091131A1 (en) | 2003-07-26 | 2006-10-26 | Use of rotigotine for the treatment of depression |
Country Status (23)
Country | Link |
---|---|
US (1) | US8754119B2 (ko) |
EP (1) | EP1648432B1 (ko) |
JP (1) | JP5001651B2 (ko) |
KR (1) | KR101140510B1 (ko) |
CN (1) | CN100430050C (ko) |
AT (1) | ATE478660T1 (ko) |
AU (1) | AU2004258697B2 (ko) |
BR (1) | BRPI0413000A (ko) |
CA (1) | CA2532859C (ko) |
DE (2) | DE10334188B4 (ko) |
DK (1) | DK1648432T3 (ko) |
EA (1) | EA009784B1 (ko) |
ES (1) | ES2351190T3 (ko) |
HK (1) | HK1091131A1 (ko) |
IL (1) | IL173028A (ko) |
IS (1) | IS8229A (ko) |
MX (1) | MXPA06000782A (ko) |
NO (1) | NO335666B1 (ko) |
NZ (1) | NZ545063A (ko) |
PL (1) | PL1648432T3 (ko) |
UA (1) | UA83493C2 (ko) |
WO (1) | WO2005009424A1 (ko) |
ZA (1) | ZA200600341B (ko) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19814084B4 (de) | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
DE10041479A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923 |
US20030026830A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
US20030027793A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
US20040048779A1 (en) * | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
US8246979B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
US8246980B2 (en) * | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
US8211462B2 (en) | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
DE10234673B4 (de) | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
DE10261696A1 (de) | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
DE10334188B4 (de) | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
DE10334187A1 (de) * | 2003-07-26 | 2005-03-03 | Schwarz Pharma Ag | Substituierte 2-Aminotetraline zur Behandlung von Depressionen |
DE10359528A1 (de) * | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
EP1547592A1 (en) | 2003-12-23 | 2005-06-29 | Schwarz Pharma Ag | Intranasal formulation of rotigotine |
DE10361258A1 (de) | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
US20050197385A1 (en) * | 2004-02-20 | 2005-09-08 | Schwarz Pharma Ag | Use of rotigotine for treatment or prevention of dopaminergic neuron loss |
DE102004014841B4 (de) * | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
WO2006032202A1 (en) | 2004-09-21 | 2006-03-30 | Shandong Luye Pharmaceutical Co., Ltd. | Long acting sustained-release formulation containing dopamine receptor agonist and the preparation method thereof |
TWI392670B (zh) * | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的2-胺基萘滿之於製造用於預防、減緩及/或治療各種類型疼痛之藥物上的用途 |
EP1987815A1 (en) * | 2007-05-04 | 2008-11-05 | Schwarz Pharma Ag | Oronasopharyngeally deliverable pharmaceutical compositions of dopamine agonists for the prevention and/or treatment of restless limb disorders |
CN101970422B (zh) * | 2007-11-28 | 2014-10-22 | Ucb制药有限公司 | 罗替高汀的多晶型物 |
MX2011006680A (es) * | 2008-12-24 | 2011-07-12 | Astrazeneca Ab | Compuestos etanaminicos y su uso para tratar la depresion. |
EP2201941A1 (de) | 2008-12-29 | 2010-06-30 | UCB Pharma GmbH | Pflaster-Herstellungstechnologie |
EP2281559A1 (en) | 2009-06-26 | 2011-02-09 | UCB Pharma GmbH | Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis |
ME03053B (me) | 2009-12-22 | 2018-10-20 | Ucb Biopharma Sprl | Polivinilpirolidon za stabilizaciju čvrste disperzije nekristalnog oblika rotigotina |
IN2012DN06562A (ko) | 2010-02-05 | 2015-10-23 | Ucb Pharma Gmbh | |
EP2585428B1 (en) | 2010-06-25 | 2017-05-10 | UCB Biopharma SPRL | Processes for the resolution of nitrogen substituted (s)-5-alkoxy-2-aminotetralin derivatives |
EP2559435A1 (en) | 2011-08-19 | 2013-02-20 | UCB Pharma GmbH | Rotigotine in the treatment of hemispatial neglect, stroke and deficits following stroke |
DE102012013421A1 (de) | 2012-07-03 | 2014-01-09 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System (TTS) mit Rotigotin |
DE102012013439A1 (de) | 2012-07-03 | 2014-01-23 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermales therapeutisches System umfassend Rotigotin und Kristallisationsinhibitor |
WO2013075823A1 (en) | 2011-11-22 | 2013-05-30 | Alfred E. Tiefenbacher (Gmbh & Co. Kg) | Transdermal therapeutic system comprising rotigotine and crystallization inhibitor |
TW201431570A (zh) | 2012-11-22 | 2014-08-16 | Ucb Pharma Gmbh | 用於經皮投服羅替戈汀(Rotigotine)之多天式貼片 |
BR112015032929B1 (pt) | 2013-07-03 | 2022-08-23 | Lts Lohmann Therapie-Systeme Ag | Sistema terapêutico transdérmico com componente eletrônico e métodos de produção de um sistema terapêutico transdérmico |
US11752110B2 (en) | 2014-05-20 | 2023-09-12 | Lts Lohmann Therapie-Systeme Ag | Transdermal delivery system including an interface mediator |
CN106456566B (zh) | 2014-05-20 | 2020-06-16 | Lts勒曼治疗系统股份公司 | 含罗替戈汀的经皮递送系统 |
CN106456567A (zh) | 2014-05-20 | 2017-02-22 | Lts勒曼治疗系统股份公司 | 在经皮递送系统中调节活性剂释放的方法 |
US9956201B2 (en) | 2014-07-21 | 2018-05-01 | Spriaso Llc | Compositions comprising bioreversible derivatives of hydroxy N-substituted-2-aminotetralins, and related dosage forms |
HUE055000T2 (hu) | 2015-02-27 | 2021-10-28 | Dechra Ltd | Étvágy stimulálása, tömegvesztés kézbentartása és anorexia kezelése kutyák és macskák esetében |
WO2018022967A1 (en) * | 2016-07-28 | 2018-02-01 | Regeneron Pharmaceuticals, Inc. | Gpr156 variants and uses thereof |
GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
WO2020212948A1 (en) | 2019-04-17 | 2020-10-22 | Compass Pathfinder Limited | Methods of treating neurocognitive disorders, chronic pain and reducing inflammation |
ES2966170T3 (es) | 2020-01-24 | 2024-04-18 | Luye Pharma Switzerland Ag | Sistema terapéutico transdérmico que comprende rotigotina y al menos un adhesivo de silicona no resistente a las aminas |
Family Cites Families (97)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US326830A (en) * | 1885-09-22 | Agitator for washing-machines | ||
DE3062971D1 (en) | 1979-09-14 | 1983-06-09 | Sandoz Ag | Derivatives of tetraline, their preparation and medicaments containing these compounds |
US4556676A (en) | 1979-11-01 | 1985-12-03 | Pfizer Inc. | Antidepressant derivatives of trans-4-phenyl-1,2,3,4-tetrahydro-1-naphthalenamine |
US4320148A (en) * | 1980-11-24 | 1982-03-16 | Smithkline Corporation | 2-Aminotetralin compounds, pharmaceutical compositions and method of producing central alpha1 agonist activity |
CH649300A5 (de) | 1981-08-07 | 1985-05-15 | Sandoz Ag | Ergopeptinderivate, ihre herstellung und verwendung. |
US5177112A (en) | 1983-01-03 | 1993-01-05 | Whitby Research, Inc. | Substituted 2-aminotetralins |
US4722933A (en) | 1985-12-20 | 1988-02-02 | Nelson Research & Development Co. | Substituted 2-aminotetralins |
US4564628A (en) * | 1983-01-03 | 1986-01-14 | Nelson Research & Development Co. | Substituted 2-aminotetralins |
DE3315272C2 (de) * | 1983-04-27 | 1986-03-27 | Lohmann Gmbh & Co Kg, 5450 Neuwied | Pharmazeutisches Produkt und Verfahren zu seiner Herstellung |
US4501890A (en) * | 1983-09-26 | 1985-02-26 | Eli Lilly And Company | Trans-(±)-2,4,6-substituted-5,5a,6,7,8,9,9a,10-octahydro-pyrimido[4,5-g]quinolines |
US4996226A (en) | 1984-08-13 | 1991-02-26 | Whitby Research, Inc. | Method and compositions for treatment of parkinsonism syndrome in mammels |
US4885308A (en) | 1984-08-13 | 1989-12-05 | Nelson Research & Development Co. | Method and compositions for treatment of parkinsonism syndrome in mammals |
DE3535929A1 (de) | 1985-10-04 | 1987-04-09 | Schering Ag | 1,2-disubstituierte ergolinderivate |
US4863970A (en) | 1986-11-14 | 1989-09-05 | Theratech, Inc. | Penetration enhancement with binary system of oleic acid, oleins, and oleyl alcohol with lower alcohols |
DE3718317A1 (de) * | 1986-12-10 | 1988-06-16 | Bayer Ag | Substituierte basische 2-aminotetraline |
FR2613365B1 (fr) | 1987-04-01 | 1989-07-28 | Adir | Nouveaux derives de l'amino tetrahydro-5, 6, 7, 8 naphto (2, 3b) furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
GB8712073D0 (en) | 1987-05-21 | 1987-06-24 | Smith Kline French Lab | Medicament |
US5656286A (en) | 1988-03-04 | 1997-08-12 | Noven Pharmaceuticals, Inc. | Solubility parameter based drug delivery system and method for altering drug saturation concentration |
CA1331191C (en) | 1988-03-25 | 1994-08-02 | Bengt Ronny Andersson | Therapeutically useful tetralin derivatives |
US5214156A (en) | 1988-03-25 | 1993-05-25 | The Upjohn Company | Therapeutically useful tetralin derivatives |
US5545755A (en) * | 1989-05-31 | 1996-08-13 | The Upjohn Company | Therapeutically useful 2-aminotetralin derivatives |
RU2086535C1 (ru) | 1989-05-31 | 1997-08-10 | Дзе Апджон Компани | Производные 1,2,3,4-тетрагидро-2-нафтиламина |
US5486611A (en) | 1989-07-13 | 1996-01-23 | The Upjohn Company | Carboxamido-(1,2N)-carbocyclic-2-aminotetralin derivatives |
US5151446A (en) | 1989-09-25 | 1992-09-29 | Northwestern University | Substituted 2-amidotetralins as melatonin agonists and antagonists |
US5071875A (en) | 1989-09-25 | 1991-12-10 | Northwestern University | Substituted 2-amidotetralins as melatonin agonists and antagonists |
US5681956A (en) | 1990-12-28 | 1997-10-28 | Neurogen Corporation | 4-aryl substituted piperazinylmethyl phenylimidazole derivatives; a new class of dopamine receptor subtype specific ligands |
US5633376A (en) | 1990-12-28 | 1997-05-27 | Neurogen Corporation | Certain aminomethyl phenylimidazole derivatives; and 4-aryl substituted piperazinyl and piperidinylmethyl phenylimidazole derivatives; a new class of dopamine receptor subtype ligands |
JP3176063B2 (ja) | 1991-04-17 | 2001-06-11 | ファルマシア・アンド・アップジョン・カンパニー | 新規中枢神経作用性置換フェニルアザシクロアルカン類 |
EP0591426A4 (en) | 1991-06-27 | 1996-08-21 | Univ Virginia Commonwealth | Sigma receptor ligands and the use thereof |
GB9202915D0 (en) | 1992-02-12 | 1992-03-25 | Wellcome Found | Chemical compounds |
DK55192D0 (da) | 1992-04-28 | 1992-04-28 | Lundbeck & Co As H | 1-piperazino-1,2-dihydroindenderivater |
US5989586A (en) | 1992-10-05 | 1999-11-23 | Cygnus, Inc. | Two-phase matrix for sustained release drug delivery device |
US5663167A (en) | 1992-12-09 | 1997-09-02 | The United States Of America As Represented By The Department Of Health And Human Services | Antipsychotic composition and method of treatment |
EP0710106A4 (en) | 1993-03-17 | 1999-07-21 | Pietr Hitzig | METHOD FOR TREATING ADDICTIVE BEHAVIOR |
SE9301732D0 (sv) | 1993-05-18 | 1993-05-18 | Haakan Wilhelm Wikstroem | New centrally acting 5-,6-,7-, and 8-substituted sulphone esters of n-monosubstituted 2-aminotetralins |
DE4325855A1 (de) | 1993-08-02 | 1995-02-09 | Boehringer Ingelheim Kg | Neue Benzoesäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
US5382596A (en) | 1993-08-05 | 1995-01-17 | Whitby Research, Inc. | Substituted 2-aminotetralins |
TW280819B (ko) | 1993-11-17 | 1996-07-11 | Sumitomo Pharma | |
GB9324018D0 (en) | 1993-11-23 | 1994-01-12 | Merck Sharp & Dohme | Therapeutic agents |
US5658955A (en) | 1994-11-01 | 1997-08-19 | Hitzig; Pietr | Combined use of dopamine and serotonin agonists in the treatment of immune disorders |
IT1276522B1 (it) | 1995-04-07 | 1997-10-31 | Elena Benincasa | Uso dello zolpidem per il trattamento terapeudico di sindromi neuropsichiatriche associate a disfunsione e di circuiti neurali dei |
US5906830A (en) | 1995-09-08 | 1999-05-25 | Cygnus, Inc. | Supersaturated transdermal drug delivery systems, and methods for manufacturing the same |
US5902603A (en) | 1995-09-14 | 1999-05-11 | Cygnus, Inc. | Polyurethane hydrogel drug reservoirs for use in transdermal drug delivery systems, and associated methods of manufacture and use |
WO1997009971A2 (en) | 1995-09-14 | 1997-03-20 | Cygnus, Inc. | High capacity, superabsorbent drug reservoirs for use in transdermal drug delivery systems |
AUPN814496A0 (en) | 1996-02-19 | 1996-03-14 | Monash University | Dermal penetration enhancer |
US6010877A (en) | 1997-01-10 | 2000-01-04 | Smithkline Beecham Corporation | cDNA clone HE8CS41 that encodes a novel 7-transmembrane receptor |
US6001861A (en) | 1998-01-16 | 1999-12-14 | Pharmacia & Upjohn Company | Use of pramipexole in the treatment of restless legs syndrome |
US6221627B1 (en) | 1997-02-24 | 2001-04-24 | Smithkline Beecham Corporation | cDNA clone HDPB130 that encodes a novel human 7-transmembrane receptor |
IT1292155B1 (it) | 1997-06-13 | 1999-01-25 | Zambon Spa | Derivati naftotiazolonici attivi sul recettore dopaminergico d 3 |
EP1021204B1 (en) | 1997-09-26 | 2005-12-28 | Noven Pharmaceuticals, Inc. | Bioadhesive compositions and methods for topical administration of active agents |
DE19814084B4 (de) | 1998-03-30 | 2005-12-22 | Lts Lohmann Therapie-Systeme Ag | D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung |
DE19830201A1 (de) | 1998-07-07 | 2000-01-13 | Boehringer Ingelheim Pharma | Mittel mit antidepressiver Wirkung |
AU5325000A (en) | 1999-06-05 | 2000-12-28 | David Houze | Solubility enhancement of drugs in transdermal drug delivery systems and methodsof use |
AR026505A1 (es) | 1999-11-23 | 2003-02-12 | Aderis Pharmaceuticals Inc | Proceso mejorado para la preparacion de aminotetralinas sustituidas con nitrogeno |
US6350773B1 (en) * | 1999-12-10 | 2002-02-26 | American Home Products Corporation | Therapeutic combinations of (S)-2-(benzylamino-methyl)-2,3,8,9,-tetrahydro 7H-1,4-dioxino{2,3-e}indol-8-one and neuroleptics for the treatment or prevention of psychotic disorders |
US6277875B1 (en) | 2000-07-17 | 2001-08-21 | Andrew J. Holman | Use of dopamine D2/D3 receptor agonists to treat fibromyalgia |
DE10041479A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung zur Verabreichung von N-0923 |
DE10041478A1 (de) * | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
US20050260577A1 (en) | 2000-10-09 | 2005-11-24 | Kay Double | Detection of neurodegenerative disorders |
DE10055742B4 (de) | 2000-11-10 | 2006-05-11 | Schwarz Pharma Ag | Neue Polyester, Verfahren zu ihrer Herstellung und aus den Polyestern hergestellte Depot-Arzneiformen |
US20020177626A1 (en) | 2001-01-19 | 2002-11-28 | Cook Graham D. | Treatment of sleep disturbances |
US20030026830A1 (en) | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
DK1256339T3 (da) * | 2001-05-08 | 2004-02-09 | Sanol Arznei Schwarz Gmbh | Transdermalt terapeutisk system for opnåelse af høje plasmaniveauer af rotigotin i behandlingen af Parkinsons sygdom |
US20030027793A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
DE60100595T2 (de) | 2001-05-08 | 2004-06-24 | Lts Lohmann Therapie-Systeme Ag | Verbessertes transdermales therapeutisches System zur Behandlung von Morbus Parkinson |
FR2829028B1 (fr) | 2001-08-29 | 2004-12-17 | Aventis Pharma Sa | Association d'un antagoniste du recepteur cb1 et d'un produit qui active la neurotransmission dopaminergique dans le cerveau, les compositions pharmaceutiques les contenant et leur utilisation pour le traitement de la maladie de |
DE10148233A1 (de) | 2001-09-28 | 2003-04-10 | Boehringer Ingelheim Pharma | Verbindungen zur Reduzierung übermäßiger Nahrungsaufnahme |
HU227543B1 (en) | 2001-09-28 | 2011-08-29 | Richter Gedeon Nyrt | N-[4-(2-piperazin- and 2-piperidin-1-yl-ethyl)-cyclohexyl]-sulfon- and sulfamides, process for their preparation, their use and pharmaceutical compositions containing them |
EP1336406A1 (en) * | 2002-02-14 | 2003-08-20 | Solvay Pharmaceuticals B.V. | Partial dopamine-D2 receptor agonist plus serotonin and/or noradrenaline inhibitory activity |
PL372393A1 (en) | 2002-02-26 | 2005-07-25 | Ortho-Mcneil Pharmaceutical Inc. | Co-therapy for the treatment of migraine comprising anticonvulsant derivatives and antimigraine agents |
US20060263419A1 (en) | 2002-03-12 | 2006-11-23 | Hans-Michael Wolff | Transdermal therapeutic system for Parkinson's Disease |
EP1494664A2 (en) | 2002-04-18 | 2005-01-12 | Pharmacia Corporation | Combinations of cox-2 inhibitors and other agents for the treatment of parkinson's disease |
US20040048779A1 (en) | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
US20060216336A1 (en) | 2002-05-07 | 2006-09-28 | Hans-Michael Wolff | Transdermal therapeutic system for Parkinson's Disease |
US8246979B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system for the administration of rotigotine |
US8246980B2 (en) | 2002-07-30 | 2012-08-21 | Ucb Pharma Gmbh | Transdermal delivery system |
DE10234673B4 (de) | 2002-07-30 | 2007-08-16 | Schwarz Pharma Ag | Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren |
US8211462B2 (en) | 2002-07-30 | 2012-07-03 | Ucb Pharma Gmbh | Hot-melt TTS for administering rotigotine |
JP4288263B2 (ja) | 2002-10-25 | 2009-07-01 | コレジウム ファーマシューティカル, インク. | p−ヒドロキシ−ミルナシプランの立体異性体およびその使用方法 |
DE60204229T2 (de) | 2002-12-02 | 2006-02-02 | Schwarz Pharma Ag | Verabreichung von Rotigotine zur Behandlung der Parkinson'schen Krankheit durch Iontophorese |
DE10261696A1 (de) | 2002-12-30 | 2004-07-15 | Schwarz Pharma Ag | Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base |
US20050037983A1 (en) * | 2003-03-11 | 2005-02-17 | Timothy Dinan | Compositions and methods for the treatment of depression and other affective disorders |
DE10334187A1 (de) | 2003-07-26 | 2005-03-03 | Schwarz Pharma Ag | Substituierte 2-Aminotetraline zur Behandlung von Depressionen |
DE10334188B4 (de) | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
US20050032873A1 (en) | 2003-07-30 | 2005-02-10 | Wyeth | 3-Amino chroman and 2-amino tetralin derivatives |
DE10359528A1 (de) | 2003-12-18 | 2005-07-28 | Schwarz Pharma Ag | (S)-2-N-Propylamino-5-hydroxytetralin als D3-agonistisches Therapeutikum |
EP1547592A1 (en) | 2003-12-23 | 2005-06-29 | Schwarz Pharma Ag | Intranasal formulation of rotigotine |
DE10361258A1 (de) | 2003-12-24 | 2005-07-28 | Schwarz Pharma Ag | Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson |
JP2007518754A (ja) | 2004-01-22 | 2007-07-12 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | モノアミン神経伝達物質再取込みインヒビターとドーパミンアゴニストを含む医薬組成物 |
US20050197385A1 (en) | 2004-02-20 | 2005-09-08 | Schwarz Pharma Ag | Use of rotigotine for treatment or prevention of dopaminergic neuron loss |
DE102004014841B4 (de) | 2004-03-24 | 2006-07-06 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms |
EA200700368A1 (ru) | 2004-08-02 | 2007-08-31 | Шварц Фарма Аг | Карбоксамиды индолизина и их аза- и диазапроизводных |
TWI392670B (zh) | 2006-06-22 | 2013-04-11 | Ucb Pharma Gmbh | 經取代的2-胺基萘滿之於製造用於預防、減緩及/或治療各種類型疼痛之藥物上的用途 |
EP1987815A1 (en) | 2007-05-04 | 2008-11-05 | Schwarz Pharma Ag | Oronasopharyngeally deliverable pharmaceutical compositions of dopamine agonists for the prevention and/or treatment of restless limb disorders |
CN101970422B (zh) | 2007-11-28 | 2014-10-22 | Ucb制药有限公司 | 罗替高汀的多晶型物 |
EP2281559A1 (en) | 2009-06-26 | 2011-02-09 | UCB Pharma GmbH | Pharmaceutical composition comprising rotigotine salts (acid or Na), especially for iontophoresis |
ME03053B (me) | 2009-12-22 | 2018-10-20 | Ucb Biopharma Sprl | Polivinilpirolidon za stabilizaciju čvrste disperzije nekristalnog oblika rotigotina |
-
2003
- 2003-07-26 DE DE10334188A patent/DE10334188B4/de not_active Expired - Fee Related
-
2004
- 2004-07-22 NZ NZ545063A patent/NZ545063A/en not_active IP Right Cessation
- 2004-07-22 UA UAA200600333A patent/UA83493C2/uk unknown
- 2004-07-22 WO PCT/EP2004/008168 patent/WO2005009424A1/de active Application Filing
- 2004-07-22 ES ES04741204T patent/ES2351190T3/es active Active
- 2004-07-22 AT AT04741204T patent/ATE478660T1/de active
- 2004-07-22 KR KR1020067001785A patent/KR101140510B1/ko not_active IP Right Cessation
- 2004-07-22 EA EA200600222A patent/EA009784B1/ru not_active IP Right Cessation
- 2004-07-22 CA CA2532859A patent/CA2532859C/en not_active Expired - Fee Related
- 2004-07-22 DK DK04741204.4T patent/DK1648432T3/da active
- 2004-07-22 AU AU2004258697A patent/AU2004258697B2/en not_active Ceased
- 2004-07-22 MX MXPA06000782A patent/MXPA06000782A/es active IP Right Grant
- 2004-07-22 US US10/565,699 patent/US8754119B2/en not_active Expired - Fee Related
- 2004-07-22 BR BRPI0413000-6A patent/BRPI0413000A/pt active Search and Examination
- 2004-07-22 JP JP2006521476A patent/JP5001651B2/ja not_active Expired - Fee Related
- 2004-07-22 PL PL04741204T patent/PL1648432T3/pl unknown
- 2004-07-22 CN CNB2004800217910A patent/CN100430050C/zh not_active Expired - Fee Related
- 2004-07-22 EP EP04741204A patent/EP1648432B1/de not_active Revoked
- 2004-07-22 DE DE502004011581T patent/DE502004011581D1/de active Active
-
2006
- 2006-01-09 IL IL173028A patent/IL173028A/en not_active IP Right Cessation
- 2006-01-12 IS IS8229A patent/IS8229A/is unknown
- 2006-02-21 NO NO20060846A patent/NO335666B1/no not_active IP Right Cessation
- 2006-09-01 ZA ZA200600341A patent/ZA200600341B/xx unknown
- 2006-10-26 HK HK06111851.9A patent/HK1091131A1/xx not_active IP Right Cessation
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL173028A0 (en) | Use of rotigotine for the treatment of depression | |
HK1100765A1 (en) | Use of rotigotine for treating and preventing parkinson's plus syndrome | |
GEP20074208B (en) | Substituted amides active at the cannabinoid-1 receptor | |
GEP20074047B (en) | Pramipexole once-daily dosage form | |
UA90518C2 (ru) | Фармацевтическая композиция в форме таблетки, которая имеет улучшеное всасывание при трансбукальном введение, которая содержит наркотический активный ингредиент и амин | |
NO20065878L (no) | Terapeutiske forbindelser | |
GEP20094723B (en) | Tetraazabenzo [e] azulene derivatives and analogs thereof | |
BR0314308A (pt) | Composto, composição farmacêutica, métodos para bloquear uma combinação de mu, kappa, delta ou receptor (heterodìmero) dos mesmos em mamìferos, para tratar ou prevenir obesidade e doenças relacionadas, para suprimir o apetite em um paciente em necessidade deste, e para realizar a perda de peso em um paciente obeso, e, uso de um composto | |
MA26939A1 (fr) | Forme posologique de medicament commandee par un hydrogel | |
RS54050B1 (en) | FORMULATIONS AND METHODS FOR THE TREATMENT OF AMYLOIDOSIS | |
BR0315580A (pt) | Derivados de metileno uréia | |
PL370529A1 (en) | Use of 2-oxo-1-pyrrolidine derivatives for the preparation of a drug | |
WO2002056745A3 (en) | Method of treating parkinson's disease | |
PT1150704E (pt) | Melagatran para o tratamento da inflamacao | |
EP1262197A3 (en) | Combination treatment for sleep disorders including sleep apnea | |
CA2432177A1 (en) | Drug for prevention and/or therapy of endometriosis | |
SI1596841T1 (sl) | Terapevtski sistem amoksicilina in klavulanske kisline | |
WO2006076568A3 (en) | Thiazolopyridines as cannabinoid receptor modulators | |
MX2008011178A (es) | Agente profilàctico o terapèutico para enfermedad oftàlmica alèrgica o enfermedad nasal alèrgica, que comprende derivado tricìclico de triazolobenzacepina. | |
WO2004073627A3 (en) | Novel therapeutic method and compositions for topical administration | |
HUP0202098A3 (en) | Use of 2-aminotetralin derivatives for production of pharmaceutical composition for the therapy of glaucoma | |
AU2003294834A1 (en) | Anthranilic acid amide derivatives and their pharmaceutical use | |
PL367628A1 (en) | Use of an alkanoyl l-carnitine for the preparation of a medication to treat anhedonia | |
TW200626129A (en) | Combinations of N-(indolecarbonyl-)piperazine derivatives and serotonin reuptake inhibitors | |
UA38697A (uk) | Спосіб лікування генералізованого пародонтиту |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20150722 |