HK1086829A1 - 4-tetrazolyl-4-phenylpiperidine derivatives for treating pain - Google Patents
4-tetrazolyl-4-phenylpiperidine derivatives for treating painInfo
- Publication number
- HK1086829A1 HK1086829A1 HK06106822.5A HK06106822A HK1086829A1 HK 1086829 A1 HK1086829 A1 HK 1086829A1 HK 06106822 A HK06106822 A HK 06106822A HK 1086829 A1 HK1086829 A1 HK 1086829A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- tetrazolyl
- treating pain
- phenylpiperidine derivatives
- phenylpiperidine
- derivatives
- Prior art date
Links
- OGPKTRWLBLRODW-UHFFFAOYSA-N 4-phenyl-4-(2h-tetrazol-5-yl)piperidine Chemical class C1CNCCC1(C=1C=CC=CC=1)C1=NNN=N1 OGPKTRWLBLRODW-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42738102P | 2002-11-18 | 2002-11-18 | |
| US46027803P | 2003-04-03 | 2003-04-03 | |
| US48848803P | 2003-07-17 | 2003-07-17 | |
| US10/714,066 US7202259B2 (en) | 2002-11-18 | 2003-11-13 | Therapeutic agents useful for treating pain |
| PCT/US2003/036742 WO2004046132A1 (en) | 2002-11-18 | 2003-11-17 | 4-tetrazolyl-4phenylpiperidine derivatives for treating pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1086829A1 true HK1086829A1 (en) | 2006-09-29 |
Family
ID=32777221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK06106822.5A HK1086829A1 (en) | 2002-11-18 | 2006-06-14 | 4-tetrazolyl-4-phenylpiperidine derivatives for treating pain |
Country Status (37)
| Country | Link |
|---|---|
| US (3) | US7202259B2 (de) |
| EP (2) | EP1803718B1 (de) |
| JP (2) | JP4601429B2 (de) |
| KR (1) | KR20050115221A (de) |
| CN (2) | CN101648941A (de) |
| AP (1) | AP2210A (de) |
| AR (1) | AR047008A1 (de) |
| AT (2) | ATE402167T1 (de) |
| AU (2) | AU2003294313B2 (de) |
| BR (1) | BR0316305A (de) |
| CA (1) | CA2506242C (de) |
| CO (1) | CO5690588A2 (de) |
| CR (2) | CR7877A (de) |
| CY (2) | CY1107682T1 (de) |
| DE (2) | DE60313021T2 (de) |
| DK (2) | DK1803718T3 (de) |
| EA (1) | EA008621B1 (de) |
| EC (1) | ECSP055840A (de) |
| ES (2) | ES2285235T3 (de) |
| GE (1) | GEP20084539B (de) |
| HK (1) | HK1086829A1 (de) |
| IL (1) | IL209352A0 (de) |
| IS (2) | IS2720B (de) |
| MA (1) | MA27565A1 (de) |
| ME (1) | MEP48108A (de) |
| MX (1) | MXPA05004669A (de) |
| MY (1) | MY135647A (de) |
| NI (1) | NI200500087A (de) |
| NO (1) | NO20052894L (de) |
| NZ (2) | NZ540068A (de) |
| OA (1) | OA13010A (de) |
| PT (2) | PT1803718E (de) |
| RS (1) | RS51047B (de) |
| SG (1) | SG165998A1 (de) |
| SI (2) | SI1562932T1 (de) |
| TW (2) | TWI343917B (de) |
| WO (1) | WO2004046132A1 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US7202259B2 (en) * | 2002-11-18 | 2007-04-10 | Euro-Celtique S.A. | Therapeutic agents useful for treating pain |
| CA2522529C (en) | 2003-04-30 | 2015-10-20 | Purdue Pharma L.P. | Tamper resistant transdermal dosage form |
| US8790689B2 (en) * | 2003-04-30 | 2014-07-29 | Purdue Pharma L.P. | Tamper resistant transdermal dosage form |
| WO2005075455A2 (en) | 2004-01-30 | 2005-08-18 | Euro-Celtique S.A. | Methods for making 4-tetrazolyl-4-phenylpiperidine compounds |
| SE0401656D0 (sv) * | 2004-06-24 | 2004-06-24 | Astrazeneca Ab | Chemical compounds |
| CA2628750C (en) * | 2005-11-21 | 2013-02-12 | Purdue Pharma L.P. | 4-oxadiazolyl-piperidine compounds and use thereof |
| US20080051380A1 (en) | 2006-08-25 | 2008-02-28 | Auerbach Alan H | Methods and compositions for treating cancer |
| WO2011056561A1 (en) | 2009-10-27 | 2011-05-12 | Beth Israel Deaconess Medical Center | Methods and compositions for the generation and use of conformation-specific antibodies |
| HUE027195T2 (en) | 2010-09-21 | 2016-10-28 | Purdue Pharma Lp | Buprenorphine analogues as opioid receptor agonists and / or antagonists |
| CN102648915B (zh) * | 2011-02-28 | 2015-04-15 | 鲁南制药集团股份有限公司 | 一种治疗或预防神经病理性疼痛的药物组合物 |
| WO2012149334A2 (en) | 2011-04-27 | 2012-11-01 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for the generation and use of conformation-specific antibodies |
| WO2014072809A2 (en) | 2012-11-09 | 2014-05-15 | Purdue Pharma L.P. | Benzomorphan analogs and the use thereof |
| AR094641A1 (es) | 2012-12-07 | 2015-08-19 | Purdue Pharma Lp | Análogos de buprenorfina |
| CA2894963A1 (en) | 2012-12-14 | 2014-06-19 | Purdue Pharma L.P. | Pyridonemorphinan analogs and biological activity on opioid receptors |
| ES2621305T3 (es) | 2012-12-14 | 2017-07-03 | Purdue Pharma Lp | Morfinanos espirocíclicos y su uso |
| US9056836B2 (en) | 2013-01-31 | 2015-06-16 | Purdue Pharma L.P. | Benzomorphan analogs and the use thereof |
| US8969358B2 (en) | 2013-03-15 | 2015-03-03 | Purdue Pharma L.P. | Buprenorphine analogs |
| WO2015097548A1 (en) | 2013-12-26 | 2015-07-02 | Purdue Pharma L.P. | 7-beta-alkyl analogs of orvinols |
| WO2015097547A1 (en) | 2013-12-26 | 2015-07-02 | Purdue Pharma L.P. | 10-substituted morphinan hydantoins |
| EP3087079B1 (de) | 2013-12-26 | 2019-04-03 | Purdue Pharma LP | Opioidrezeptormodulierende oxabicyclo[2.2.2]oktanmorphinane |
| CA2934913A1 (en) | 2013-12-26 | 2015-07-02 | Purdue Pharma L.P. | Ring-contracted morphinans and the use thereof |
| US9340542B2 (en) | 2013-12-26 | 2016-05-17 | Purdue Pharma L.P. | Propellane-based compounds and the use thereof |
| US10550088B2 (en) | 2013-12-27 | 2020-02-04 | Purdue Pharma L.P. | 6-substituted and 7-substituted morphinan analogs and the use thereof |
| US10030021B2 (en) | 2014-05-27 | 2018-07-24 | Purdue Pharma L.P. | Spirocyclic morphinans and use thereof |
| CA2951697A1 (en) | 2014-06-13 | 2015-12-17 | Purdue Pharma L.P. | Azamophinan derivatives and use thereof |
| MA41125A (fr) | 2014-12-05 | 2017-10-10 | Purdue Pharma Lp | Dérivés de 6.7-cyclomorphinane et leur utilisation |
| AU2017238208B2 (en) | 2016-03-22 | 2022-01-06 | Regents Of The University Of Minnesota | Combination for treating pain |
| JP2019522032A (ja) | 2016-07-29 | 2019-08-08 | ヤンセン ファーマシューティカ エヌ．ベー． | 前立腺癌の治療方法 |
| WO2018125716A1 (en) | 2017-01-02 | 2018-07-05 | Purdue Pharma L.P. | Morphinan derivatives and use thereof |
| JP2024518804A (ja) * | 2021-05-21 | 2024-05-02 | パーデュー、ファーマ、リミテッド、パートナーシップ | 間質性膀胱炎／膀胱痛症候群を処置する方法 |
| WO2023250190A1 (en) * | 2022-06-24 | 2023-12-28 | Purdue Pharma L.P. | Methods of treating or preventing overactive bladder syndrome |
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-
2003
- 2003-11-13 US US10/714,066 patent/US7202259B2/en active Active
- 2003-11-17 AT AT07006697T patent/ATE402167T1/de active
- 2003-11-17 ES ES03789796T patent/ES2285235T3/es not_active Expired - Lifetime
- 2003-11-17 SI SI200330814T patent/SI1562932T1/sl unknown
- 2003-11-17 SI SI200331358T patent/SI1803718T1/sl unknown
- 2003-11-17 AT AT03789796T patent/ATE358674T1/de active
- 2003-11-17 DK DK07006697T patent/DK1803718T3/da active
- 2003-11-17 WO PCT/US2003/036742 patent/WO2004046132A1/en active Search and Examination
- 2003-11-17 DE DE60313021T patent/DE60313021T2/de not_active Expired - Lifetime
- 2003-11-17 AP AP2005003297A patent/AP2210A/xx active
- 2003-11-17 JP JP2004570427A patent/JP4601429B2/ja not_active Expired - Fee Related
- 2003-11-17 PT PT07006697T patent/PT1803718E/pt unknown
- 2003-11-17 CN CN200910173679A patent/CN101648941A/zh active Pending
- 2003-11-17 RS YUP-2005/0375A patent/RS51047B/sr unknown
- 2003-11-17 NZ NZ540068A patent/NZ540068A/en not_active IP Right Cessation
- 2003-11-17 DK DK03789796T patent/DK1562932T3/da active
- 2003-11-17 OA OA1200500145A patent/OA13010A/en unknown
- 2003-11-17 SG SG200703631-2A patent/SG165998A1/en unknown
- 2003-11-17 AU AU2003294313A patent/AU2003294313B2/en not_active Ceased
- 2003-11-17 EP EP07006697A patent/EP1803718B1/de not_active Expired - Lifetime
- 2003-11-17 NZ NZ572685A patent/NZ572685A/en not_active IP Right Cessation
- 2003-11-17 ES ES07006697T patent/ES2312150T3/es not_active Expired - Lifetime
- 2003-11-17 DE DE60322451T patent/DE60322451D1/de not_active Expired - Lifetime
- 2003-11-17 PT PT03789796T patent/PT1562932E/pt unknown
- 2003-11-17 EA EA200500726A patent/EA008621B1/ru not_active IP Right Cessation
- 2003-11-17 CN CNB2003801035027A patent/CN100567288C/zh not_active Expired - Fee Related
- 2003-11-17 CA CA2506242A patent/CA2506242C/en not_active Expired - Fee Related
- 2003-11-17 ME MEP-481/08A patent/MEP48108A/xx unknown
- 2003-11-17 MX MXPA05004669A patent/MXPA05004669A/es active IP Right Grant
- 2003-11-17 EP EP03789796A patent/EP1562932B9/de not_active Expired - Lifetime
- 2003-11-17 BR BR0316305-9A patent/BR0316305A/pt not_active IP Right Cessation
- 2003-11-17 KR KR1020057008903A patent/KR20050115221A/ko active IP Right Grant
- 2003-11-17 GE GEAP20038846A patent/GEP20084539B/en unknown
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2005
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- 2005-04-22 NI NI200500087A patent/NI200500087A/es unknown
- 2005-05-20 CO CO05048789A patent/CO5690588A2/es not_active Application Discontinuation
- 2005-06-07 EC EC2005005840A patent/ECSP055840A/es unknown
- 2005-06-13 MA MA28335A patent/MA27565A1/fr unknown
- 2005-06-14 NO NO20052894A patent/NO20052894L/no not_active Application Discontinuation
- 2005-06-16 CR CR7877A patent/CR7877A/es unknown
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2006
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2007
- 2007-03-28 US US11/729,660 patent/US7687518B2/en not_active Expired - Lifetime
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2008
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2009
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- 2009-11-10 US US12/615,510 patent/US8026254B2/en not_active Expired - Lifetime
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2010
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20131117 |