HK1079549A1 - Muteins of placental growth factor type 1, preparation method and application thereof - Google Patents

Muteins of placental growth factor type 1, preparation method and application thereof

Info

Publication number
HK1079549A1
HK1079549A1 HK05111674A HK05111674A HK1079549A1 HK 1079549 A1 HK1079549 A1 HK 1079549A1 HK 05111674 A HK05111674 A HK 05111674A HK 05111674 A HK05111674 A HK 05111674A HK 1079549 A1 HK1079549 A1 HK 1079549A1
Authority
HK
Hong Kong
Prior art keywords
preparation
growth factor
muteins
placental growth
application
Prior art date
Application number
HK05111674A
Other languages
English (en)
Inventor
Domenico Maglione
Mauro Battisti
Ettore Conti
Giuseppe Salvia
Marina Tucci
Alberto Mion
Original Assignee
Geymonat Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11456311&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1079549(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Geymonat Spa filed Critical Geymonat Spa
Publication of HK1079549A1 publication Critical patent/HK1079549A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK05111674A 2002-05-17 2005-12-19 Muteins of placental growth factor type 1, preparation method and application thereof HK1079549A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2002RM000277A ITRM20020277A1 (it) 2002-05-17 2002-05-17 Muteine del fattore di crescita placentare tipo 1, metodo di preparazione e loro applicazioni.
PCT/IT2003/000296 WO2003097688A2 (en) 2002-05-17 2003-05-19 Muteins of placental growth factor type 1, preparation method and application thereof

Publications (1)

Publication Number Publication Date
HK1079549A1 true HK1079549A1 (en) 2006-04-07

Family

ID=11456311

Family Applications (1)

Application Number Title Priority Date Filing Date
HK05111674A HK1079549A1 (en) 2002-05-17 2005-12-19 Muteins of placental growth factor type 1, preparation method and application thereof

Country Status (22)

Country Link
US (1) US7314734B2 (pl)
EP (1) EP1506295B1 (pl)
JP (1) JP4230450B2 (pl)
KR (1) KR101022934B1 (pl)
CN (1) CN1323167C (pl)
AT (1) ATE488590T1 (pl)
AU (1) AU2003234066B2 (pl)
BR (1) BR0309966A (pl)
CA (1) CA2485587C (pl)
CY (1) CY1111431T1 (pl)
DE (1) DE60334986D1 (pl)
DK (1) DK1506295T3 (pl)
ES (1) ES2356360T3 (pl)
HK (1) HK1079549A1 (pl)
HR (1) HRP20041178B1 (pl)
IT (1) ITRM20020277A1 (pl)
MX (1) MXPA04011405A (pl)
PL (1) PL209955B1 (pl)
PT (1) PT1506295E (pl)
RU (1) RU2344172C2 (pl)
WO (1) WO2003097688A2 (pl)
ZA (1) ZA200409943B (pl)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8409815B2 (en) 2002-11-16 2013-04-02 Siemens Healthcare Diagnostics Products Gmbh sCD40L and placental growth factor (PLGF) used as a biochemical marker combination in cardiovascular diseases
DE102005022047A1 (de) 2005-05-09 2006-11-30 Dade Behring Marburg Gmbh Bindungspartner des Plazentalen Wachstumsfaktors insbesondere gegen den Plazentalen Wachstumsfaktor gerichtete Antikörper, ihre Herstellung und Verwendung
JP2009100680A (ja) * 2007-10-23 2009-05-14 Univ Nagoya ヒト全身性強皮症動物モデルの作製方法、ヒト全身性強皮症動物モデル及びその用途
CN101918834B (zh) 2008-01-07 2014-05-28 奥索临床诊断有限公司 用于同时分析能够彼此络合的蛋白质的校准物/对照物
RU2010133157A (ru) 2008-01-07 2012-02-20 Орто-Клиникал Дайэгностикс, Инк. (Us) Определение комплекса sflt-1:ангиогенный фактор
EP2295449A1 (en) * 2009-09-09 2011-03-16 Dompe PHA.R.MA S.p.A. PLGF-1 in homodimeric form
CN103087153B (zh) * 2011-10-28 2015-05-06 上海市第一人民医院 一类新的抑制新生血管的小肽及其应用
WO2014191553A2 (en) 2013-05-31 2014-12-04 Cobiores Nv Heart failure treatment
CN109134650A (zh) * 2018-09-10 2019-01-04 宁波奥丞生物科技有限公司 抗人plgf单克隆抗体的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1242149B (it) 1990-09-27 1994-02-16 Consiglio Nazionale Ricerche Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi
EP0506477B1 (en) * 1991-03-28 1999-06-23 Merck & Co. Inc. Vascular endothelial cell growth factor C subunit
SE9601245D0 (sv) * 1996-03-29 1996-03-29 Pharmacia Ab Chimeric superantigens and their use
DE19748734A1 (de) * 1997-11-05 1999-05-06 Biotechnolog Forschung Gmbh Verfahren zur Gewinnung von biologisch aktiven Dimeren von rekombinanten humanen Wachstumsfaktoren aus der Cystein-Knoten-Familie sowie Verwendung der gewonnenen Dimere
CN1402733A (zh) * 1999-06-03 2003-03-12 人体基因组科学有限公司 血管生成蛋白及其应用
ES2260234T3 (es) * 2000-05-12 2006-11-01 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw. Utilizacion de inhibidores del factor de crecimiento placentario para el tratamiento de la angiogenesis patologica, de la arteriogenesis patologica, de la inflamacion, de la formacion tumoral y/o de la perdida vascular.

Also Published As

Publication number Publication date
PL209955B1 (pl) 2011-11-30
CN1653177A (zh) 2005-08-10
MXPA04011405A (es) 2005-02-14
US20050176634A1 (en) 2005-08-11
KR101022934B1 (ko) 2011-03-16
WO2003097688A3 (en) 2004-02-26
AU2003234066B2 (en) 2009-04-23
CN1323167C (zh) 2007-06-27
AU2003234066A1 (en) 2003-12-02
DK1506295T3 (da) 2011-03-07
KR20040111639A (ko) 2004-12-31
ITRM20020277A1 (it) 2003-11-17
RU2344172C2 (ru) 2009-01-20
PL372492A1 (pl) 2005-07-25
JP4230450B2 (ja) 2009-02-25
HRP20041178A2 (en) 2005-10-31
CY1111431T1 (el) 2015-08-05
ITRM20020277A0 (it) 2002-05-17
PT1506295E (pt) 2011-02-23
HRP20041178B1 (hr) 2013-11-22
WO2003097688A2 (en) 2003-11-27
DE60334986D1 (de) 2010-12-30
WO2003097688A9 (en) 2005-01-06
ES2356360T3 (es) 2011-04-07
US7314734B2 (en) 2008-01-01
CA2485587C (en) 2012-08-21
BR0309966A (pt) 2005-03-01
CA2485587A1 (en) 2003-11-27
EP1506295A2 (en) 2005-02-16
ZA200409943B (en) 2005-09-28
JP2006508637A (ja) 2006-03-16
ATE488590T1 (de) 2010-12-15
RU2004137000A (ru) 2005-06-10
EP1506295B1 (en) 2010-11-17

Similar Documents

Publication Publication Date Title
HK1079549A1 (en) Muteins of placental growth factor type 1, preparation method and application thereof
RU2009100884A (ru) Пептидные фрагменты для индукции синтеза белков внеклеточного матрикса
WO2003083485A3 (en) Protein for use in hypoxia related conditions
HUP0004560A2 (hu) Törést gyógyító PTHrP analógok
ATE502953T1 (de) Peptide zur förderung des haarwachstums und zur verbesserung von falten und kosmetische zusammensetzungen, die diese enthalten
EP1614675A3 (en) Amino acids with affinity for the alpha-2-delta protein
HUP0302026A2 (hu) Növekedési hormon szekrécióját fokozó triptofánszármazékok, azokat tartalmazó gyógyszerkészítmények és alkalmazásuk
DE69900756D1 (de) Verwendung von hmg proteinen zur herstellung von arzneimitteln mit zytotoxischer wirkung
NO331277B1 (no) Farmasoytisk sammensetning omfattende polypetid/nukleinsyre for behandling av retinale degenererende sykdommer, vektor, isolert polypeptid, renset antistoff og anvendelse av polypeptid, nukleinsyre og antistoff, samt fremgangsmater og kit
JP2021080273A (ja) ミノキシジルとペプチドの結合体
KR950032165A (ko) 토코페롤 유도체
FR2846883B1 (fr) Composition cosmetique comprenant, comme ingredient actif, au moins un peptide et utilisation de ce peptide
DE60100500D1 (de) Suspension enthaltend ein epi-hne protein, verfahren zu ihrer herstellung, daraus hergestelltes trockenpulveraerosol, arzneimittelzusammensetzungen enthaltend diese suspension oder dieses aerosol und ihre verwendungen
AU2003271811A8 (en) Novel derivatives of 4,4'-dithiobis-(3-aminobutane-1-sulphonates) and compositions containing same
WO2004016741A3 (en) Prenylation inhibitors containing dimethyl-cyclobutane and methods of their synthesis and use
WO2002004487A3 (de) Verfahren zur gewinnung und anwendung neuer humaner defensine als biologisch aktive eiweisstoffe zur behandlung von infektionen und anderen erkrankungen
AU2003292326A1 (en) Cosmetic or pharmaceutical composition comprising peptides with the sequence arg-gly-ser
ATE391510T1 (de) Verwendung eines lupinkonglutins für die behandlung von diabetes typ ii
DE69834929D1 (de) Verwendung eines organspezifischen ernährungmittels
SE9403055D0 (sv) A new human peptide antibiotic (FALL-39) and its use
CA2165039A1 (en) Cyclohexapeptides and their mixtures, a process for preparing them, and their use
WO2002007676A3 (en) Compounds having affinity for the granulocyte-colony stimulating factor receptor (g-csfr)
JP6312191B2 (ja) 血管弛緩作用を有するペプチド及び血管弛緩剤
GB2391548A (en) Polypeptides derived from amyloid precursor peptide (APP) and their uses
DK0423326T3 (da) Hidtil ukendt fysiologisk aktivt peptid og calcium-metabolisme-regulerende middel, der omfatter peptidet som effektiv besta

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20160519