DE60334986D1 - Muteine des placental growth factor type 1, herstellungsmethode und anwendung davon - Google Patents

Muteine des placental growth factor type 1, herstellungsmethode und anwendung davon

Info

Publication number
DE60334986D1
DE60334986D1 DE60334986T DE60334986T DE60334986D1 DE 60334986 D1 DE60334986 D1 DE 60334986D1 DE 60334986 T DE60334986 T DE 60334986T DE 60334986 T DE60334986 T DE 60334986T DE 60334986 D1 DE60334986 D1 DE 60334986D1
Authority
DE
Germany
Prior art keywords
growth factor
placental growth
mutines
manufacturing
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60334986T
Other languages
English (en)
Inventor
Domenico Maglione
Mauro Battisti
Ettore Conti
Giuseppe Salvia
Marina Tucci
Alberto Mion
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Geymonat SpA
Original Assignee
Geymonat SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11456311&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60334986(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Geymonat SpA filed Critical Geymonat SpA
Application granted granted Critical
Publication of DE60334986D1 publication Critical patent/DE60334986D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Urology & Nephrology (AREA)
  • Plant Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60334986T 2002-05-17 2003-05-19 Muteine des placental growth factor type 1, herstellungsmethode und anwendung davon Expired - Lifetime DE60334986D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2002RM000277A ITRM20020277A1 (it) 2002-05-17 2002-05-17 Muteine del fattore di crescita placentare tipo 1, metodo di preparazione e loro applicazioni.
PCT/IT2003/000296 WO2003097688A2 (en) 2002-05-17 2003-05-19 Muteins of placental growth factor type 1, preparation method and application thereof

Publications (1)

Publication Number Publication Date
DE60334986D1 true DE60334986D1 (de) 2010-12-30

Family

ID=11456311

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60334986T Expired - Lifetime DE60334986D1 (de) 2002-05-17 2003-05-19 Muteine des placental growth factor type 1, herstellungsmethode und anwendung davon

Country Status (22)

Country Link
US (1) US7314734B2 (de)
EP (1) EP1506295B1 (de)
JP (1) JP4230450B2 (de)
KR (1) KR101022934B1 (de)
CN (1) CN1323167C (de)
AT (1) ATE488590T1 (de)
AU (1) AU2003234066B2 (de)
BR (1) BR0309966A (de)
CA (1) CA2485587C (de)
CY (1) CY1111431T1 (de)
DE (1) DE60334986D1 (de)
DK (1) DK1506295T3 (de)
ES (1) ES2356360T3 (de)
HK (1) HK1079549A1 (de)
HR (1) HRP20041178B1 (de)
IT (1) ITRM20020277A1 (de)
MX (1) MXPA04011405A (de)
PL (1) PL209955B1 (de)
PT (1) PT1506295E (de)
RU (1) RU2344172C2 (de)
WO (1) WO2003097688A2 (de)
ZA (1) ZA200409943B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004046722A2 (de) 2002-11-16 2004-06-03 Dade Behring Marburg Gmbh Scd40l, papp-a und plazentaler-wachstumsfaktor (pigf) als biochemische markerkombinationen bei kardiovaskulären erkrankungen
DE102005022047A1 (de) * 2005-05-09 2006-11-30 Dade Behring Marburg Gmbh Bindungspartner des Plazentalen Wachstumsfaktors insbesondere gegen den Plazentalen Wachstumsfaktor gerichtete Antikörper, ihre Herstellung und Verwendung
JP2009100680A (ja) * 2007-10-23 2009-05-14 Univ Nagoya ヒト全身性強皮症動物モデルの作製方法、ヒト全身性強皮症動物モデル及びその用途
CN101918834B (zh) 2008-01-07 2014-05-28 奥索临床诊断有限公司 用于同时分析能够彼此络合的蛋白质的校准物/对照物
CN101918839A (zh) * 2008-01-07 2010-12-15 奥索临床诊断有限公司 sFlt-1:血管生成因子络合物的测定
EP2295449A1 (de) * 2009-09-09 2011-03-16 Dompe PHA.R.MA S.p.A. PLGF-1 in homodimerer Form
CN103087153B (zh) 2011-10-28 2015-05-06 上海市第一人民医院 一类新的抑制新生血管的小肽及其应用
AU2014273027B2 (en) 2013-05-31 2019-07-04 Cobiores Nv Human PlGF-2 for the prevention or treatment of heart failure
CN109134650A (zh) * 2018-09-10 2019-01-04 宁波奥丞生物科技有限公司 抗人plgf单克隆抗体的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1242149B (it) * 1990-09-27 1994-02-16 Consiglio Nazionale Ricerche Sequenza di nucleotidi codificante per una proteina umana con proprieta' regolative dell'angiogenesi
DE69229454T2 (de) * 1991-03-28 2000-01-05 Merck & Co Inc Untereinheit-C des vaskulären endothelialen Zellwachstumsfaktors
SE9601245D0 (sv) * 1996-03-29 1996-03-29 Pharmacia Ab Chimeric superantigens and their use
DE19748734A1 (de) * 1997-11-05 1999-05-06 Biotechnolog Forschung Gmbh Verfahren zur Gewinnung von biologisch aktiven Dimeren von rekombinanten humanen Wachstumsfaktoren aus der Cystein-Knoten-Familie sowie Verwendung der gewonnenen Dimere
KR20020092779A (ko) * 1999-06-03 2002-12-12 휴먼 게놈 사이언시즈, 인코포레이티드 혈관형성 단백질 및 이의 용도
AU2001265953B2 (en) * 2000-05-12 2005-09-29 D. Collen Research Foundation Vzw Use of inhibitors of placental growth factor for the treatment of pathological angiogenesis, pathological arteriogenesis, inflammation, tumour formation and/or vascular leakage

Also Published As

Publication number Publication date
DK1506295T3 (da) 2011-03-07
ITRM20020277A0 (it) 2002-05-17
JP4230450B2 (ja) 2009-02-25
EP1506295A2 (de) 2005-02-16
PL372492A1 (en) 2005-07-25
US20050176634A1 (en) 2005-08-11
KR20040111639A (ko) 2004-12-31
EP1506295B1 (de) 2010-11-17
WO2003097688A9 (en) 2005-01-06
ATE488590T1 (de) 2010-12-15
KR101022934B1 (ko) 2011-03-16
CA2485587C (en) 2012-08-21
HK1079549A1 (en) 2006-04-07
US7314734B2 (en) 2008-01-01
AU2003234066B2 (en) 2009-04-23
JP2006508637A (ja) 2006-03-16
HRP20041178A2 (en) 2005-10-31
ITRM20020277A1 (it) 2003-11-17
RU2004137000A (ru) 2005-06-10
BR0309966A (pt) 2005-03-01
PT1506295E (pt) 2011-02-23
RU2344172C2 (ru) 2009-01-20
PL209955B1 (pl) 2011-11-30
HRP20041178B1 (hr) 2013-11-22
MXPA04011405A (es) 2005-02-14
WO2003097688A3 (en) 2004-02-26
CN1323167C (zh) 2007-06-27
WO2003097688A2 (en) 2003-11-27
ES2356360T3 (es) 2011-04-07
AU2003234066A1 (en) 2003-12-02
CY1111431T1 (el) 2015-08-05
CA2485587A1 (en) 2003-11-27
CN1653177A (zh) 2005-08-10
ZA200409943B (en) 2005-09-28

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