HK1049167B - 替利霉素的球狀附聚物、其製備方法及其在製備藥劑中的用途 - Google Patents

替利霉素的球狀附聚物、其製備方法及其在製備藥劑中的用途 Download PDF

Info

Publication number
HK1049167B
HK1049167B HK03101349.3A HK03101349A HK1049167B HK 1049167 B HK1049167 B HK 1049167B HK 03101349 A HK03101349 A HK 03101349A HK 1049167 B HK1049167 B HK 1049167B
Authority
HK
Hong Kong
Prior art keywords
telithromycin
spherical
preparation
agglomerates
acetone
Prior art date
Application number
HK03101349.3A
Other languages
English (en)
Chinese (zh)
Other versions
HK1049167A1 (en
Inventor
Godard Jean-Yves
Rognon Valerie
Original Assignee
Aventis Pharma S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9549351&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1049167(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Aventis Pharma S.A. filed Critical Aventis Pharma S.A.
Publication of HK1049167A1 publication Critical patent/HK1049167A1/xx
Publication of HK1049167B publication Critical patent/HK1049167B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK03101349.3A 1999-08-26 2000-08-28 替利霉素的球狀附聚物、其製備方法及其在製備藥劑中的用途 HK1049167B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9910810A FR2797875B1 (fr) 1999-08-26 1999-08-26 Agglomerats spheriques de telithromycine, leur procede de preparation et leur application dans la preparation de formes pharmaceutiques
FR99/10810 1999-08-26
PCT/FR2000/002393 WO2001014393A2 (fr) 1999-08-26 2000-08-28 Agglomerats spheriques de telithromycine, leur procede de preparation et leur application dans la preparation de formes pharmaceutiques

Publications (2)

Publication Number Publication Date
HK1049167A1 HK1049167A1 (en) 2003-05-02
HK1049167B true HK1049167B (zh) 2005-08-19

Family

ID=9549351

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03101349.3A HK1049167B (zh) 1999-08-26 2000-08-28 替利霉素的球狀附聚物、其製備方法及其在製備藥劑中的用途

Country Status (34)

Country Link
US (1) US6825218B1 (https=)
EP (1) EP1212336B1 (https=)
JP (1) JP4871467B2 (https=)
KR (1) KR100718222B1 (https=)
CN (1) CN1183151C (https=)
AR (1) AR025398A1 (https=)
AT (1) ATE255590T1 (https=)
AU (1) AU774385B2 (https=)
BR (1) BR0013569B1 (https=)
CA (1) CA2382497C (https=)
CO (1) CO5190666A1 (https=)
CZ (1) CZ2002594A3 (https=)
DE (1) DE60006976T2 (https=)
DK (1) DK1212336T3 (https=)
EA (1) EA005080B1 (https=)
ES (1) ES2209970T3 (https=)
FR (1) FR2797875B1 (https=)
HK (1) HK1049167B (https=)
HR (1) HRP20020167B1 (https=)
HU (1) HU229075B1 (https=)
IL (2) IL148128A0 (https=)
ME (2) MEP20108A (https=)
MX (1) MXPA02001988A (https=)
NO (1) NO322622B1 (https=)
PL (1) PL204100B1 (https=)
PT (1) PT1212336E (https=)
RS (1) RS50433B (https=)
SI (1) SI1212336T1 (https=)
SK (1) SK287588B6 (https=)
TR (1) TR200200506T2 (https=)
TW (1) TWI272949B (https=)
UA (1) UA73523C2 (https=)
WO (1) WO2001014393A2 (https=)
ZA (1) ZA200201599B (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9902202D0 (sv) * 1999-06-10 1999-06-10 Astra Ab Production of aggregates
FR2821747B1 (fr) * 2001-03-09 2004-07-02 Ethypharm Lab Prod Ethiques Suspension de telithromycine a gout masque
JP2005533121A (ja) * 2002-07-19 2005-11-04 アベンティス・ファーマ・ソシエテ・アノニム テリスロマイシンの味覚マスキングされた経口組成物
WO2004009059A1 (en) * 2002-07-19 2004-01-29 Aventis Pharma S.A. Taste masked oral composition of telithromycin
US20040013737A1 (en) * 2002-07-19 2004-01-22 Philippe Becourt Taste masked oral composition of telithromycin
PL224720B1 (pl) * 2003-02-21 2017-01-31 Univ Bath Sposób wytwarzania cząstek krystalicznych, cząstki krystaliczne oraz kompozycja farmaceutyczna je zawierająca
WO2005007143A2 (en) * 2003-07-14 2005-01-27 The Board Of Trustees Of The University Of Illinois Use of makrolides and ketolides for the treatment of tuberculosis
WO2007039914A2 (en) * 2005-10-06 2007-04-12 Alembic Limited Novel polymorphs of telithromycin
US20090075917A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched telithromycin
KR101324862B1 (ko) * 2011-07-12 2013-11-01 (주)에이에스텍 클로피도그렐 황산수소염의 구형 입자, 이를 포함하는 약학적 조성물 및 이의 제조방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0130160B1 (en) * 1983-06-22 1988-01-07 The Ohio State University Research Foundation Small particle formation
JPH02227130A (ja) * 1989-02-28 1990-09-10 Taisho Pharmaceut Co Ltd 球形微小凍結粒子の製造法
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Also Published As

Publication number Publication date
CO5190666A1 (es) 2002-08-29
CA2382497A1 (fr) 2001-03-01
CA2382497C (fr) 2011-06-28
WO2001014393A2 (fr) 2001-03-01
PL204100B1 (pl) 2009-12-31
JP2003507484A (ja) 2003-02-25
DK1212336T3 (da) 2004-03-15
TR200200506T2 (tr) 2002-08-21
MEP20108A (en) 2010-06-10
NO20020926D0 (no) 2002-02-26
SK2532002A3 (en) 2002-09-10
ZA200201599B (en) 2003-04-30
HRP20020167B1 (en) 2006-06-30
YU13202A (sh) 2004-09-03
FR2797875A1 (fr) 2001-03-02
NO322622B1 (no) 2006-11-06
SI1212336T1 (en) 2004-04-30
BR0013569A (pt) 2002-05-14
ME00112B (me) 2010-10-10
FR2797875B1 (fr) 2001-10-19
EP1212336B1 (fr) 2003-12-03
IL148128A (en) 2006-10-31
EA005080B1 (ru) 2004-10-28
PL353137A1 (en) 2003-10-20
AR025398A1 (es) 2002-11-27
AU7018100A (en) 2001-03-19
US6825218B1 (en) 2004-11-30
TWI272949B (en) 2007-02-11
ATE255590T1 (de) 2003-12-15
KR20020033771A (ko) 2002-05-07
HK1049167A1 (en) 2003-05-02
UA73523C2 (uk) 2005-08-15
HUP0202842A3 (en) 2003-03-28
EP1212336A2 (fr) 2002-06-12
HRP20020167A2 (en) 2003-06-30
AU774385B2 (en) 2004-06-24
CN1371386A (zh) 2002-09-25
CN1183151C (zh) 2005-01-05
CZ2002594A3 (cs) 2002-09-11
NO20020926L (no) 2002-02-26
PT1212336E (pt) 2004-04-30
ES2209970T3 (es) 2004-07-01
HUP0202842A2 (hu) 2003-01-28
EA200200294A1 (ru) 2002-08-29
IL148128A0 (en) 2002-09-12
DE60006976D1 (de) 2004-01-15
HU229075B1 (hu) 2013-07-29
DE60006976T2 (de) 2004-10-21
BR0013569B1 (pt) 2014-02-25
SK287588B6 (sk) 2011-03-04
WO2001014393A3 (fr) 2001-06-21
MXPA02001988A (es) 2002-08-20
RS50433B (sr) 2009-12-31
JP4871467B2 (ja) 2012-02-08
KR100718222B1 (ko) 2007-05-15

Similar Documents

Publication Publication Date Title
DE68903442T2 (de) Feste und poroese einheitsform, enthaltend mikropartikel und/oder nanopartikel und verfahren zu ihrer herstellung.
HK1049167A1 (en) Spherical telithromycin clusters, method for the producing and use thereof in the preparation of pharmaceutical forms
HK79791A (en) Solid galenical forms for oral application containing 9-deoxo-11-deoxy-9,11-(imino(2-(2-methoxyethoxy)ethyliden)-oxy)-(9s)-erythromycin, and process for their preparation
CN1244869A (zh) 克拉霉素的o型结晶
CN1249686A (zh) 帕罗西丁制剂
CN1518449A (zh) 盖敌伏赛星的儿科制剂
EP1189690B1 (en) Method for production of microcapsules
JP2002501903A (ja) アミノ酸ベースの材料を含有する薬剤組成物の噴霧乾燥
JPH10505822A (ja) 共−乾燥されたスクラルファートゲル及びポリアルコールを含む製薬学的組成物
CN1474828A (zh) 具有新的结晶结构的红霉素衍生物及其制备方法
EP0982348B1 (de) Polymerzusammensetzung und Verfahren zu deren Herstellung
CN1365732A (zh) 纳米生肌制剂药物及其制备方法
JP2550340B2 (ja) 安定なセラペプタ−ゼ複合体
HK1059937B (en) Erythromycin derivative having novel crystal structures and processes for their production
WO2009116960A1 (ru) Фармацевтическая композиция и способ её получения
CN1368134A (zh) 纳米四圣制剂药物及其制备方法
CN1368331A (zh) 纳米药墨制剂药物及其制备方法

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150828