HK1048257A1 - 用於治療人體炎症的6-甲氧基-2-萘乙酸前驅藥 - Google Patents

用於治療人體炎症的6-甲氧基-2-萘乙酸前驅藥

Info

Publication number
HK1048257A1
HK1048257A1 HK03100400.1A HK03100400A HK1048257A1 HK 1048257 A1 HK1048257 A1 HK 1048257A1 HK 03100400 A HK03100400 A HK 03100400A HK 1048257 A1 HK1048257 A1 HK 1048257A1
Authority
HK
Hong Kong
Prior art keywords
methoxy
treating inflammation
naphthylacetic acid
acid prodrugs
prodrugs
Prior art date
Application number
HK03100400.1A
Other languages
English (en)
Inventor
N Ekwuribe Nnochiri
A Dyakonov Tatyana
Original Assignee
Biocon Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocon Ltd filed Critical Biocon Ltd
Publication of HK1048257A1 publication Critical patent/HK1048257A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/265—Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic, or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK03100400.1A 1999-10-27 2003-01-16 用於治療人體炎症的6-甲氧基-2-萘乙酸前驅藥 HK1048257A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16186499P 1999-10-27 1999-10-27
PCT/US2000/041692 WO2001030338A2 (en) 1999-10-27 2000-10-27 6-methoxy-2-naphthylacetic acid prodrugs for treating inflammation

Publications (1)

Publication Number Publication Date
HK1048257A1 true HK1048257A1 (zh) 2003-03-28

Family

ID=22583099

Family Applications (2)

Application Number Title Priority Date Filing Date
HK03100399.4A HK1048256A1 (zh) 1999-10-27 2003-01-16 用於治療人體炎症的6-甲氧基-2-萘乙酸前驅藥組合物
HK03100400.1A HK1048257A1 (zh) 1999-10-27 2003-01-16 用於治療人體炎症的6-甲氧基-2-萘乙酸前驅藥

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK03100399.4A HK1048256A1 (zh) 1999-10-27 2003-01-16 用於治療人體炎症的6-甲氧基-2-萘乙酸前驅藥組合物

Country Status (20)

Country Link
US (3) US6525098B1 (zh)
EP (2) EP1223926A2 (zh)
JP (2) JP2003512424A (zh)
KR (2) KR20020043248A (zh)
CN (2) CN1413108A (zh)
AU (2) AU1576101A (zh)
BR (2) BR0015121A (zh)
CA (2) CA2389181A1 (zh)
CZ (2) CZ20021435A3 (zh)
HK (2) HK1048256A1 (zh)
HU (2) HUP0203321A2 (zh)
IL (2) IL149257A0 (zh)
MX (2) MXPA02004355A (zh)
NO (2) NO20022000L (zh)
NZ (2) NZ518554A (zh)
PL (2) PL354895A1 (zh)
RU (2) RU2002113657A (zh)
TW (1) TWI262791B (zh)
WO (2) WO2001030338A2 (zh)
ZA (2) ZA200203229B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI262791B (en) * 1999-10-27 2006-10-01 Nobex Corp 6-methoxy-2-naphthylacetic acid prodrugs
CA2491127A1 (en) 2002-07-03 2004-01-15 Nitromed, Inc. Nitrosated nonsteroidal antiinflammatory compounds, compositions and methods of use
CA2493156A1 (en) * 2002-07-29 2004-02-05 Nitromed, Inc. Cyclooxygenase-2 selective inhibitors, compositions and methods of use
US8062653B2 (en) 2009-02-18 2011-11-22 Bezwada Biomedical, Llc Controlled release of nitric oxide and drugs from functionalized macromers and oligomers
EP2398761A4 (en) * 2009-02-18 2015-11-04 Bezwada Biomedical Llc CONTROLLED RELEASE OF NITRIC OXIDE AND MEDICINES FROM FUNCTIONALIZED MACROMERS AND OLIGOMERS
JP2012522796A (ja) * 2009-04-02 2012-09-27 アラーガン インコーポレイテッド プロスタグランジンｅレセプター拮抗薬
CN101928227A (zh) * 2009-12-16 2010-12-29 天津工业大学 6-甲氧基-2-萘乙酸与水杨酰苯胺类化合物的互联体前药制备方法及应用

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Also Published As

Publication number Publication date
EP1223922A2 (en) 2002-07-24
NO20022000D0 (no) 2002-04-26
NO20022001D0 (no) 2002-04-26
HK1048256A1 (zh) 2003-03-28
AU2919601A (en) 2001-05-08
HUP0203790A2 (hu) 2003-04-28
NZ518554A (en) 2004-05-28
CZ20021433A3 (cs) 2002-08-14
IL149258A0 (en) 2002-11-10
CA2387098A1 (en) 2001-05-03
IL149257A0 (en) 2002-11-10
TWI262791B (en) 2006-10-01
EP1223926A2 (en) 2002-07-24
NZ518553A (en) 2004-02-27
HUP0203790A3 (en) 2003-05-28
WO2001030338A8 (en) 2002-11-21
WO2001030338A3 (en) 2002-01-31
US6525098B1 (en) 2003-02-25
KR20020043248A (ko) 2002-06-08
WO2001030338A2 (en) 2001-05-03
CZ20021435A3 (cs) 2002-08-14
HUP0203321A2 (hu) 2003-02-28
US20050054735A1 (en) 2005-03-10
NO20022000L (no) 2002-06-27
WO2001030334A3 (en) 2002-03-21
ZA200203231B (en) 2003-07-23
BR0015121A (pt) 2002-07-02
HU0203790D0 (en) 2002-12-28
WO2001030334A2 (en) 2001-05-03
BR0015122A (pt) 2002-07-09
CA2389181A1 (en) 2001-05-03
MXPA02004357A (es) 2002-11-07
JP2003512424A (ja) 2003-04-02
AU1576101A (en) 2001-05-08
CN1413106A (zh) 2003-04-23
JP2003512425A (ja) 2003-04-02
US20030069309A1 (en) 2003-04-10
KR20020043249A (ko) 2002-06-08
CN1413108A (zh) 2003-04-23
RU2002113657A (ru) 2004-01-10
ZA200203229B (en) 2003-07-23
PL354895A1 (en) 2004-03-22
RU2002113661A (ru) 2004-01-10
MXPA02004355A (es) 2002-11-07
NO20022001L (no) 2002-06-25
PL354510A1 (en) 2004-01-26

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