IT1283638B1 - Procedimento per la preparazione di un naftilbutanone - Google Patents
Procedimento per la preparazione di un naftilbutanoneInfo
- Publication number
- IT1283638B1 IT1283638B1 IT96MI001605A ITMI961605A IT1283638B1 IT 1283638 B1 IT1283638 B1 IT 1283638B1 IT 96MI001605 A IT96MI001605 A IT 96MI001605A IT MI961605 A ITMI961605 A IT MI961605A IT 1283638 B1 IT1283638 B1 IT 1283638B1
- Authority
- IT
- Italy
- Prior art keywords
- naftilbutanone
- procedure
- preparation
- ethylenedioxybutene
- dioxybuten
- Prior art date
Links
- RIOQSEWOXXDEQQ-UHFFFAOYSA-N triphenylphosphine Chemical compound C1=CC=CC=C1P(C=1C=CC=CC=1)C1=CC=CC=C1 RIOQSEWOXXDEQQ-UHFFFAOYSA-N 0.000 abstract 2
- WDSDJCZPORLTOK-UHFFFAOYSA-N 2-[2-(6-methoxynaphthalen-2-yl)ethenyl]-1,4-dioxane Chemical compound C1=CC2=CC(OC)=CC=C2C=C1C=CC1COCCO1 WDSDJCZPORLTOK-UHFFFAOYSA-N 0.000 abstract 1
- AYFJBMBVXWNYLT-UHFFFAOYSA-N 2-bromo-6-methoxynaphthalene Chemical compound C1=C(Br)C=CC2=CC(OC)=CC=C21 AYFJBMBVXWNYLT-UHFFFAOYSA-N 0.000 abstract 1
- WJCCNRRUTSLHLJ-UHFFFAOYSA-N 2-ethenyl-1,4-dioxane Chemical compound C=CC1COCCO1 WJCCNRRUTSLHLJ-UHFFFAOYSA-N 0.000 abstract 1
- BLXXJMDCKKHMKV-UHFFFAOYSA-N Nabumetone Chemical compound C1=C(CCC(C)=O)C=CC2=CC(OC)=CC=C21 BLXXJMDCKKHMKV-UHFFFAOYSA-N 0.000 abstract 1
- 229910002666 PdCl2 Inorganic materials 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- PIBWKRNGBLPSSY-UHFFFAOYSA-L palladium(II) chloride Chemical compound Cl[Pd]Cl PIBWKRNGBLPSSY-UHFFFAOYSA-L 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
- C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Catalysts (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT96MI001605A IT1283638B1 (it) | 1996-07-29 | 1996-07-29 | Procedimento per la preparazione di un naftilbutanone |
| US08/900,224 US5777170A (en) | 1996-07-29 | 1997-07-24 | Process for the preparation of a naphthylbutanone |
| AT97202306T ATE193514T1 (de) | 1996-07-29 | 1997-07-24 | Verfahren zur herstellung eines naphthylbutanons |
| DE69702165T DE69702165T2 (de) | 1996-07-29 | 1997-07-24 | Verfahren zur Herstellung eines Naphthylbutanons |
| ES97202306T ES2146066T3 (es) | 1996-07-29 | 1997-07-24 | Procedimiento para la preparacion de una naftilbutanona. |
| EP97202306A EP0822174B1 (en) | 1996-07-29 | 1997-07-24 | Process for the preparation of a naphthylbutanone |
| JP9203238A JPH10139712A (ja) | 1996-07-29 | 1997-07-29 | ナフチルブタノンの製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT96MI001605A IT1283638B1 (it) | 1996-07-29 | 1996-07-29 | Procedimento per la preparazione di un naftilbutanone |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI961605A0 ITMI961605A0 (it) | 1996-07-29 |
| ITMI961605A1 ITMI961605A1 (it) | 1998-01-29 |
| IT1283638B1 true IT1283638B1 (it) | 1998-04-23 |
Family
ID=11374691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT96MI001605A IT1283638B1 (it) | 1996-07-29 | 1996-07-29 | Procedimento per la preparazione di un naftilbutanone |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5777170A (it) |
| EP (1) | EP0822174B1 (it) |
| JP (1) | JPH10139712A (it) |
| AT (1) | ATE193514T1 (it) |
| DE (1) | DE69702165T2 (it) |
| ES (1) | ES2146066T3 (it) |
| IT (1) | IT1283638B1 (it) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6436990B1 (en) | 1999-10-27 | 2002-08-20 | Nobex Corporation | 6-methoxy-2-naphthylacetic acid prodrugs |
| TWI262791B (en) | 1999-10-27 | 2006-10-01 | Nobex Corp | 6-methoxy-2-naphthylacetic acid prodrugs |
| US6552078B2 (en) | 1999-10-27 | 2003-04-22 | Nobex Corp | 6-methoxy-2-naphthylacetic acid prodrugs |
| CN113908883B (zh) * | 2021-10-13 | 2023-08-29 | 安徽美致诚药业有限公司 | 一种1-(4-甲氧基苯基)丙酮的合成方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1497109A (en) * | 1975-10-29 | 1978-01-05 | Beecham Group Ltd | Naphthalene derivatives |
| US4194010A (en) * | 1975-10-29 | 1980-03-18 | Beecham Group Limited | Pharmacologically active enol ether compounds |
| GB2014993B (en) * | 1977-11-03 | 1982-05-12 | Beecham Group Ltd | Chemical compounds |
| CA1142965A (en) * | 1979-06-08 | 1983-03-15 | Alexander C. Goudie | Substituted decalins, their preparation and use |
| GB8603768D0 (en) * | 1986-02-15 | 1986-03-19 | Beecham Group Plc | Process |
| US5225603A (en) * | 1987-07-14 | 1993-07-06 | Hoechst Celanese Corporation | Preparation of 4-(6'-methoxy-2'-naphthyl)-3-buten-2-one |
| CA2004042C (en) * | 1988-12-08 | 1999-11-02 | Napp Technologies, Inc. | Method of preparation of nabumetone |
| US5600009A (en) * | 1996-04-09 | 1997-02-04 | Hoechst Celanese Corporation | Use of 4-substituted 2-butanones to prepare nabumetone |
-
1996
- 1996-07-29 IT IT96MI001605A patent/IT1283638B1/it active IP Right Grant
-
1997
- 1997-07-24 AT AT97202306T patent/ATE193514T1/de not_active IP Right Cessation
- 1997-07-24 US US08/900,224 patent/US5777170A/en not_active Expired - Fee Related
- 1997-07-24 DE DE69702165T patent/DE69702165T2/de not_active Expired - Fee Related
- 1997-07-24 ES ES97202306T patent/ES2146066T3/es not_active Expired - Lifetime
- 1997-07-24 EP EP97202306A patent/EP0822174B1/en not_active Expired - Lifetime
- 1997-07-29 JP JP9203238A patent/JPH10139712A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP0822174B1 (en) | 2000-05-31 |
| JPH10139712A (ja) | 1998-05-26 |
| ATE193514T1 (de) | 2000-06-15 |
| ITMI961605A0 (it) | 1996-07-29 |
| DE69702165D1 (de) | 2000-07-06 |
| ITMI961605A1 (it) | 1998-01-29 |
| EP0822174A1 (en) | 1998-02-04 |
| ES2146066T3 (es) | 2000-07-16 |
| DE69702165T2 (de) | 2000-10-19 |
| US5777170A (en) | 1998-07-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted |