HK1045648B - Aplidine treatment of cancers - Google Patents

Aplidine treatment of cancers Download PDF

Info

Publication number
HK1045648B
HK1045648B HK02106981.6A HK02106981A HK1045648B HK 1045648 B HK1045648 B HK 1045648B HK 02106981 A HK02106981 A HK 02106981A HK 1045648 B HK1045648 B HK 1045648B
Authority
HK
Hong Kong
Prior art keywords
aplidine
dose
patients
infusion
mcg
Prior art date
Application number
HK02106981.6A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1045648A1 (en
Inventor
Glynn Thomas Faircloth
Chris Twelves
Luis Paz-Ares
Original Assignee
Pharma Mar, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9927006.8A external-priority patent/GB9927006D0/en
Priority claimed from GB0005701A external-priority patent/GB0005701D0/en
Priority claimed from GB0007639A external-priority patent/GB0007639D0/en
Priority claimed from GB0015496A external-priority patent/GB0015496D0/en
Priority claimed from GB0025209A external-priority patent/GB0025209D0/en
Application filed by Pharma Mar, S.A. filed Critical Pharma Mar, S.A.
Publication of HK1045648A1 publication Critical patent/HK1045648A1/en
Publication of HK1045648B publication Critical patent/HK1045648B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/15—Depsipeptides; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
HK02106981.6A 1999-11-15 2000-11-15 Aplidine treatment of cancers HK1045648B (en)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
GBGB9927006.8A GB9927006D0 (en) 1999-11-15 1999-11-15 Aplidine treatment of cancers
GB9927006.8 1999-11-15
GB0005701.8 2000-03-09
GB0005701A GB0005701D0 (en) 2000-03-09 2000-03-09 Antitumor utility of aplidine
GB0007639A GB0007639D0 (en) 2000-03-29 2000-03-29 Antitumour and anti-angiogenic compound
GB0007639.8 2000-03-29
GB0015496A GB0015496D0 (en) 2000-06-23 2000-06-23 Antitumour and anti-angiogenic compound
GB0015496.3 2000-06-23
GB0025209A GB0025209D0 (en) 2000-10-13 2000-10-13 Treatment of cancers
GB0025209.8 2000-10-13
PCT/GB2000/004349 WO2001035974A2 (en) 1999-11-15 2000-11-15 Aplidine treatment of cancers

Publications (2)

Publication Number Publication Date
HK1045648A1 HK1045648A1 (en) 2002-12-06
HK1045648B true HK1045648B (en) 2007-09-21

Family

ID=27515929

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02106981.6A HK1045648B (en) 1999-11-15 2000-11-15 Aplidine treatment of cancers

Country Status (27)

Country Link
US (1) US20090298752A1 (https=)
EP (1) EP1229922B1 (https=)
JP (1) JP2003514025A (https=)
KR (1) KR100518986B1 (https=)
CN (1) CN1423564A (https=)
AT (1) ATE363910T1 (https=)
AU (1) AU780417B2 (https=)
BG (1) BG65381B1 (https=)
BR (1) BR0015811A (https=)
CA (1) CA2391502A1 (https=)
CY (1) CY1106825T1 (https=)
CZ (1) CZ302498B6 (https=)
DE (1) DE60035120T2 (https=)
DK (1) DK1229922T3 (https=)
ES (1) ES2288486T3 (https=)
HK (1) HK1045648B (https=)
HU (1) HUP0203906A2 (https=)
IL (1) IL149488A0 (https=)
MX (1) MXPA02004862A (https=)
NO (1) NO330719B1 (https=)
NZ (1) NZ518847A (https=)
PL (1) PL200922B1 (https=)
PT (1) PT1229922E (https=)
RU (1) RU2261104C2 (https=)
SI (1) SI1229922T1 (https=)
SK (1) SK287762B6 (https=)
WO (1) WO2001035974A2 (https=)

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GB9803448D0 (en) 1998-02-18 1998-04-15 Pharma Mar Sa Pharmaceutical formulation
UA76718C2 (uk) 2000-06-30 2006-09-15 Фарма Мар, С.А. Протипухлинні похідні аплідину
CZ2003993A3 (cs) 2000-10-12 2004-02-18 Pharma Mar, S. A. Léčivo pro léčení rakoviny podáváním aplidinu nebo analogu aplidinu a protektoru kosterního svalstva
WO2003033013A1 (en) * 2001-10-19 2003-04-24 Pharma Mar, S.A. Use of aplidine for the treatment of pancreatic cancer
BR0213424A (pt) * 2001-10-19 2004-12-14 Pharma Mar Sa Uso aperfeiçoado de composto antitumoral na terapia contra câncer
WO2004080421A2 (en) * 2003-03-12 2004-09-23 Pharma Mar, S.A. Improved antitumoral treatments
ATE406171T1 (de) * 2003-03-12 2008-09-15 Dana Farber Cancer Inst Inc Aplidine zur behandlung von multiplem myelom
CN101389347B (zh) * 2006-02-28 2013-03-27 法马马有限公司 提高的抗肿瘤治疗
JP5547487B2 (ja) * 2006-11-03 2014-07-16 ネルビアーノ・メデイカル・サイエンシーズ・エツセ・エルレ・エルレ 抗癌化合物の投与方法
RU2360712C1 (ru) * 2007-10-02 2009-07-10 Федеральное государственное учреждение "Ростовский научно-исследовательский онкологический институт Росмедтехнологий" Способ лечения местно-распространенного неоперабельного рака прямой кишки
AU2008313627A1 (en) * 2007-10-19 2009-04-23 Pharma Mar, S.A. Improved antitumoral treatments
US20110009335A1 (en) * 2008-03-07 2011-01-13 Pharma Mar, S.A. Anticancer Treatments
CN103463020B (zh) * 2013-09-23 2015-11-25 李淑兰 Lycojaponicumin A在制备治疗肾癌药物中的应用
HRP20231233T1 (hr) 2017-04-27 2024-01-19 Pharma Mar, S.A. Antitumorski spojevi

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US4493796A (en) * 1980-09-12 1985-01-15 Board Of Trustees, Univ. Of Ill. Didemnins A, B, C, and derivatives thereof, as antiviral agents
IT1153974B (it) * 1982-09-23 1987-01-21 Erba Farmitalia Composizioni farmacologiche a base di cisplatino e metodo per il loro ottenimento
ATE74761T1 (de) * 1985-09-20 1992-05-15 Cernitin Sa Verwendung von pflanzenpollenextrakten zur herstellung von das wachstum von tumorzellen hemmenden pharmazeutischen praeparaten und verfahren zu ihrer herstellung.
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FR2698543B1 (fr) * 1992-12-02 1994-12-30 Rhone Poulenc Rorer Sa Nouvelles compositions à base de taxoides.
US5462726A (en) * 1993-12-17 1995-10-31 Bristol-Myers Squibb Company Method of inhibiting side effects of solvents containing ricinoleic acid or castor oil or derivatives thereof employing a thromboxane A2 receptor antagonist and pharmaceutical compositions containing such solvents
JPH09507233A (ja) * 1993-12-29 1997-07-22 マトリクス ファーマスーティカル，インコーポレイティド 細胞増殖性疾患に罹る宿主の治療方法及び治療のための組成物
US5861439A (en) * 1994-11-14 1999-01-19 Alza Corporation Method for enhanced electrotransport agent delivery
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UA76718C2 (uk) * 2000-06-30 2006-09-15 Фарма Мар, С.А. Протипухлинні похідні аплідину
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CZ2003993A3 (cs) * 2000-10-12 2004-02-18 Pharma Mar, S. A. Léčivo pro léčení rakoviny podáváním aplidinu nebo analogu aplidinu a protektoru kosterního svalstva
AU2002224417A1 (en) * 2000-10-18 2002-04-29 Immunex Corporation Methods for treating il-18 mediated disorders
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WO2003033013A1 (en) * 2001-10-19 2003-04-24 Pharma Mar, S.A. Use of aplidine for the treatment of pancreatic cancer
ATE406171T1 (de) * 2003-03-12 2008-09-15 Dana Farber Cancer Inst Inc Aplidine zur behandlung von multiplem myelom
WO2004080421A2 (en) * 2003-03-12 2004-09-23 Pharma Mar, S.A. Improved antitumoral treatments
CA2519234A1 (en) * 2003-03-21 2004-10-07 Madeleine M. Joullie Tamandarin analogs and fragments thereof and methods of making and using
EP1639090A4 (en) * 2003-06-09 2008-04-16 Univ Michigan COMPOSITIONS AND METHODS OF TREATMENT AND DIAGNOSIS OF CANCER
CN101389347B (zh) * 2006-02-28 2013-03-27 法马马有限公司 提高的抗肿瘤治疗
AU2008313627A1 (en) * 2007-10-19 2009-04-23 Pharma Mar, S.A. Improved antitumoral treatments

Also Published As

Publication number Publication date
CN1423564A (zh) 2003-06-11
CA2391502A1 (en) 2001-05-25
AU1402301A (en) 2001-05-30
BG65381B1 (bg) 2008-05-30
PL355335A1 (en) 2004-04-19
NO330719B1 (no) 2011-06-20
MXPA02004862A (es) 2003-01-28
US20090298752A1 (en) 2009-12-03
ATE363910T1 (de) 2007-06-15
NO20022293D0 (no) 2002-05-14
CZ302498B6 (cs) 2011-06-15
ES2288486T3 (es) 2008-01-16
PL200922B1 (pl) 2009-02-27
BR0015811A (pt) 2002-08-06
PT1229922E (pt) 2007-09-12
AU780417B2 (en) 2005-03-17
BG106714A (en) 2003-02-28
CZ20021697A3 (cs) 2003-02-12
NO20022293L (no) 2002-07-05
NZ518847A (en) 2004-02-27
RU2002115864A (ru) 2004-01-20
SK287762B6 (sk) 2011-09-05
HK1045648A1 (en) 2002-12-06
WO2001035974A3 (en) 2001-11-01
SK6592002A3 (en) 2003-08-05
JP2003514025A (ja) 2003-04-15
KR20020064313A (ko) 2002-08-07
DE60035120D1 (de) 2007-07-19
EP1229922B1 (en) 2007-06-06
EP1229922A2 (en) 2002-08-14
RU2261104C2 (ru) 2005-09-27
SI1229922T1 (sl) 2008-04-30
IL149488A0 (en) 2002-11-10
KR100518986B1 (ko) 2005-10-06
DE60035120T2 (de) 2008-01-31
DK1229922T3 (da) 2007-10-08
WO2001035974A2 (en) 2001-05-25
HUP0203906A2 (en) 2003-03-28
CY1106825T1 (el) 2012-05-23

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20111115